AMGEN INC — Director's Dealing 2022

May 10, 2022

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: AMGEN INC (AMGN)
CIK: 0000318154
Period of Report: 2022-05-05

Reporting Person: Santos Esteban (EVP, Operations)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2022-05-05	Common Stock	F	589	$236.10	Disposed	57661	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	802	Indirect

Footnotes

F1: These shares include the following Restricted Stock Units (RSUs) granted under the Company's equity plans: 1,342 RSUs which vest on 5/3/2023; 2,268 RSUs which vest in installments of 1,117 on 5/5/2023 and 1,151 on 5/5/2024; 3,964 RSUs which vest in two installments of 1,308 on 4/30/2023 and 4/30/2024 and one installment of 1,348 on 4/30/2025; and 3,637 RSUs which will vest in two installments of 1,200 on 5/2/2024 and on 5/2/2025, and one installment of 1,237 on 5/2/2026. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis.

F2: These shares include 396 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited to the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount.

F3: These shares are acquired under the Company's 401(k) Plan and represent interests in the Company's stock fund as of this filing.