Alkermes plc. — Director's Dealing 2023

May 10, 2023

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2023-05-09

Reporting Person: Wysenski Nancy (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2023-05-09	Ordinary Shares	M	35000	$31.13	Acquired	50829	Direct
2023-05-09	Ordinary Shares	M	6250	$31.13	Acquired	57079	Direct
2023-05-09	Ordinary Shares	S	41250	$31.2433	Disposed	15829	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2023-05-09	Non Qualified Stock Option (Right to Buy)	$31.13	M	35000	Disposed	2023-05-15	Ordinary Shares (35000)	Direct
2023-05-09	Non Qualified Stock Option (Right to Buy)	$31.13	M	6250	Disposed	2023-05-15	Ordinary Shares (6250)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	11242	Indirect

Footnotes

F1: This exercise and sale of options was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 26, 2023. These options were scheduled to expire on May 15, 2023.

F2: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $31.23 to $31.33. Full information regarding the number of shares sold at each separate price can be provided to the issuer, any security holder of the issuer or the SEC staff upon request.

F3: The reporting person is a trustee and a beneficiary of The Nancy J. Wysenski Revocable Trust, established on September 23, 2014 ("The Nancy J. Wysenski Revocable Trust").

F4: These options are fully vested in accordance with their terms.