Alkermes plc. — Director's Dealing 2018

Feb 21, 2018

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2018-02-16

Reporting Person: FRATES JAMES M (SVP, Alks Inc; CFO ALKS)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2018-02-17	Ordinary Shares	M	3000	—	Acquired	147039	Direct
2018-02-17	Ordinary Shares	F	929	$67.26	Disposed	146110	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2018-02-16	Restricted Stock Unit Award	$0	A	13500	Acquired		Ordinary Shares (13500)	Direct
2018-02-16	Employee Stock Option (Right to Buy)	$67.26	A	54500	Acquired	2028-02-16	Ordinary Shares (54500)	Direct
2018-02-17	Restricted Stock Unit Award	$0	M	3000	Disposed		Ordinary Shares (3000)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	4000	Indirect
Ordinary Shares	31940	Indirect
Ordinary Shares	11421	Indirect

Footnotes

F1: Shares held by James M. Frates Grantor Retained Annuity Trust dated March 14, 2014 (the "2014 GRAT"). The Reporting Person is a trustee and beneficiary of the 2014 GRAT and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2014 GRAT.

F2: Shares held by the James M. Frates Grantor Retained Annuity Trust No. 2 dated November 25, 2015 (the "2015 GRAT No. 2"). The Reporting Person is a trustee and beneficiary of the 2015 GRAT No. 2 and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2015 GRAT No. 2.

F3: Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing on 2/16/19.

F4: Shares subject to the stock option award vest in four equal annual installments commencing on 2/16/2019.

F5: Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing on 2/17/18.