Alkermes plc. — Director's Dealing 2016

May 23, 2016

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2016-05-21

Reporting Person: BIBERSTEIN KATHRYN L (EVP/CLO/CCO Alks Inc; Sec ALKS)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2016-05-21	Ordinary Shares	M	4500	—	Acquired	36076	Direct
2016-05-21	Ordinary Shares	F	1521	$42.98	Disposed	34555	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2016-05-21	Restricted Stock Unit Award	$0	M	4500	Disposed		Ordinary Shares (4500)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	94000	Indirect

Footnotes

F1: Shares held by the Kathryn L. Biberstein 2015 Annuity Trust dated December 11, 2015 (the "2015 GRAT"). The Reporting Person is a trustee and beneficiary of the 2015 GRAT and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2015 GRAT.

F2: This RSU award is fully vested in accordance with its terms.