Alkermes plc. — Director's Dealing 2016

Mar 1, 2016

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2016-02-26

Reporting Person: FRATES JAMES M (SVP, Alks Inc; CFO ALKS)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2016-02-26	Ordinary Shares	M	2625	—	Acquired	26659	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2016-02-26	Restricted Stock Unit Award	$0	M	2625	Disposed		Ordinary Shares (2625)	Direct
2016-02-29	Employee Stock Option (Right to Buy)	$32.27	A	76000	Acquired	2026-02-28	Ordinary Shares (76000)	Direct
2016-02-29	Restricted Stock Unit Award	$0	A	18000	Acquired		Ordinary Shares (18000)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	4000	Indirect
Ordinary Shares	50801	Indirect
Ordinary Shares	41423	Indirect
Ordinary Shares	30000	Indirect

Footnotes

F1: Excludes 30,000 shares previously owned directly which were contributed to the James M. Frates Grantor Retained Annuity Trust No. 2 dated November 25, 2015 (the "2015 GRAT No. 2") on November 30, 2015, which was exempt from reporting obligations by virtue of Rule 16a-13 promulgated under the Securities Exchange Act of 1934, as amended.

F2: Shares held by James M. Frates Grantor Retained Annuity Trust dated March 14, 2014 (the "GRAT"). The Reporting Person is a trustee and beneficiary of the GRAT and may be deemed to hold voting and dispositive power with regard to the reported shares held by the GRAT.

F3: Shares held by the James M. Frates Grantor Retained Annuity Trust dated May 29, 2015 (the "2015 GRAT"). The Reporting Person is a trustee and beneficiary of the 2015 GRAT and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2015 GRAT.

F4: Shares held by the 2015 GRAT No. 2. The Reporting Person is a trustee and beneficiary of the 2015 GRAT No. 2 and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2015 GRAT No. 2.

F5: Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing 2/26/2016.

F6: Shares subject to the stock option award vest in four equal annual installments commencing on 3/1/2017.

F7: Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing 3/1/2017.