Alkermes plc. — Director's Dealing 2015

May 26, 2015

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2015-05-26

Reporting Person: Cooke Shane (President, Alkermes plc)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2015-05-26	Ordinary Shares	M	18000	$14.60	Acquired	55880	Direct
2015-05-26	Ordinary Shares	S	17300	$60.2919	Disposed	38580	Direct
2015-05-26	Ordinary Shares	S	700	$60.8071	Disposed	37880	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2015-05-26	Employee Stock Option (Right to Buy)	$14.60	M	18000	Disposed	2021-10-05	Ordinary Shares (18000)	Direct

Footnotes

F1: This option exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $59.76 to $60.73. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F4: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $60.78 to $60.82. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F5: The option becomes exercisable in equal annual installments over a four year period, at the rate of 25% per year commencing on 10/5/12.