Alkermes plc. — Director's Dealing 2012

Dec 5, 2012

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2012-12-05

Reporting Person: FRATES JAMES M (SVP & CFO, Alkermes plc)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2012-12-05	Ordinary Shares	M	3002	$7.36	Acquired	102713	Direct
2012-12-05	Ordinary Shares	S	3002	$19.64	Disposed	99711	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2012-12-05	Non Qualified Stock Option (Right to Buy)	$7.36	M	3002	Disposed	2012-12-12	Ordinary Shares (3002)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	4000	Indirect

Footnotes

F1: This option exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $19.61 to $19.71. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F4: These options are fully vested in accordance with their terms.