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ALK-Abelló

Annual Report (ESEF) Feb 10, 2021

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ALK - 2020 Annual Report

Management's review

Introduction

2020 represented the final year of ALK's strategic transformation, and our focus remained on the relentless execution of our goals.

2020 highlights

  • Succeed in North America
  • Complete and commercialise the tablet portfolio for all relevant ages
  • Consumer engagement and new horizons
  • Optimise for excellence
  • Other ALK launches
    • ITULATEK™ tablet for tree pollen allergy in Canada
    • Annual general meeting elects Anders Hedegaard as new Chairman of ALK’s Board
    • RAGWIZAX® for ragweed allergy is approved for children in Europe
    • ALK launches klarify digital platform in Denmark
    • ALK launches klarify digital platform in Ireland
    • COVID begins to impact business operations and clinical activities
    • New clinical Phase III trial for ALK’s house dust mite tablet initiated in China
    • ALK secures rights to market OTIPRIO™ in the USA
    • ALK announces drug discovery partnership with American biotech company X-Chem
    • ALK launches klarify digital platform in Slovakia
    • ALK launches klarify digital platform in the USA
    • ALK updates its full-year financial outlook to reflect improved earnings and cash flow as well as growth at the lower end of the guidance range
    • RAGWITEK® for ragweed allergy is approved for children in Canada
  • Q1 report: Revenue up 10% with tablet sales up 38% and EBITDA up 49%
  • Q2 report: Revenue unchanged with tablet sales up 25% and EBITDA up 213%
  • Q3 report: Revenue up 7% with tablet sales up 52% and EBITDA up 61%
  • Full-year 2020 financial results: Revenue up 8% with tablet sales up 42% and EBITDA up 64%

ALK at a glance

Key figures

  • Established: 1923
  • Employees: ~2,500
  • Markets: 41
  • Production sites: 4
  • Patients in treatment with ALK products*: ~2m
  • Revenue: DKK bn
    • 2011: 2.3
    • 2012: 2.2
    • 2013: 2.3
    • 2014: 2.4
    • 2015: 2.6
    • 2016: 2.9
    • 2017: 2.9
    • 2018: 3.0
    • 2019: 3.3
    • 2020: 3.5
  • Development in revenue: +8%
  • SLIT-tablets (% growth in local currencies)**: +42%
  • SCIT/SLIT-drops (% growth in local currencies)**: +28%
  • Other (% growth in local currencies)**: +45%
  • The number of the most common global respiratory allergies covered by ALK's tablet portfolio: 5
  • Participated in clinical trials for the tablets: >23,000

* Covering AIT and anaphylaxis
** Includes certain milestone payments from partnerships in the period 2011 to 2016

Global presence

ALK is a global allergy solutions company with a wide range of treatments, products and services to meet the unique needs of allergy sufferers, their families and doctors. Headquartered in Hørsholm, Denmark, the company is listed on Nasdaq Copenhagen (ALKB:DC/OMX: ALK B).

  • International markets: ~2,500 employees
  • Revenue:
    • North America: 11%
    • Europe: 73%
    • Other: 16%
  • ALK’s unique manufacturing processes ensure its products meet required quality standards and represent a significant barrier to potential competitors, making them an important factor in maintaining ALK’s market position.

ALK's business model

As a global allergy solutions company with a century of knowledge and expertise, ALK helps people to take control of their allergies and their lives.

Value created

  • Patients: ALK’s tablet portfolio is helping to democratise AIT by covering the most common respiratory allergies, and bringing new treatment options to people without easy access to allergy specialists.
  • Doctors: ALK helps allergists to drive better access and outcomes for all AIT-eligible patients, reaching out with support, disease information and treatment options.
  • Our people: ALK is committed to a sustainable working life and keeps a constant focus on being a safe place to work for motivated and satisfied employees.
  • Society: ALK addresses profound societal challenges by producing medicines for the leading cause of lost productivity and lost work days. The company partners with payers and health authorities to advance registered, documented AIT products and is a signatory of the United Nations Global Compact.
  • Our investors: ALK works to create long-term value for its shareholders.

Key resources

  • Our people and culture: Around 2,500 highly-skilled employees live our cultural beliefs every day in their work to help more people with allergy.
  • Scientific knowledge: ALK continuously applies its scientific knowledge to help people take control of their allergies and their lives.
  • Allergy solutions for life: People with allergies often endure a decade or more of symptoms before turning to AIT. Through information resources, services and products, ALK is working to support people with allergy early in their disease journey, smoothing the path to treatment.
  • Raw materials: Allergenic source materials, such as grass pollen and house dust mites, are the main ingredients of our products. Every year the company grows, collects or harvests several tonnes of allergens.
  • Active Pharmaceutical Ingredient (API) production: Allergens undergo thorough analysis, standardisation and quality control, so that naturally occurring variations are minimised, ensuring quality and consistency in the finished products. APIs are purified, then formulated for subcutaneous injections, sublingual drops or sublingual tablets.
  • Finished production/natural allergens: ALK’s biological medicines are derived from natural resources, such as pollen, which it harvests, standardises and quality controls at its own facilities.
  • Sales and partnerships: In addition to its own sales organisation, ALK partners for growth with leading specialty pharma companies worldwide. ALK is present in 41 markets, either directly or via partnerships.
  • R&D: The completion of the tablet portfolio remains the primary focus of ALK’s R&D efforts. In addition, the company is conducting research into innovative solutions for high-impact allergic conditions – such as food allergies.
  • Packaging and distribution: Following careful quality control, the finished products are labelled, packaged and distributed.

Megatrends shaping allergy

  • Most common chronic disease in the world: ~500m people around the world are affected and consume products and services worth more than DKK 100 billion annually.
  • Shift towards evidence-based medicine: In Europe, authorities, prescribers and payers are increasingly turning to registered and documented products to treat allergies.
  • Food allergy: If you are allergic to a specific food, exposure may trigger an acute allergic reaction – anaphylaxis – for which adrenaline auto-injectors are an effective rescue medication. In addition, recent advances in food AIT hold promise of a better life for people with food allergy.

Letter from the Chairman and CEO

2020 highlights

ALK at a glance

Letter from the Chairman and CEO

2021 outlook

2021 outlook

ALK expects growth across all sales regions in 2020.

Financial highlights and key ratios

Sales and market trends

COVID-19: The defining challenge of 2020

Financial review of 2020

Q4 review

Income statement

Statement of comprehensive income

Cash flow statement

Balance sheet

Statement of changes in equity

Notes

Parent company financial statements

Income statement

Balance sheet

Statement of changes in equity

Notes

Strategic transformation

Strategy update

Succeed in North America

Complete and commercialise the tablet portfolio for all relevant ages

Consumer engagement and new horizons

Optimise for excellence

Lead the way – people and planet

Medium-term financial ambitions

Sustainability

Governance and ownership

Risk management

Remuneration

Board of Directors

Board of Management

Consolidated financial statements

2021 outlook

Financial highlights and key ratios

Sales and market trends

COVID-19: The defining challenge of 2020

Financial review of 2020

Q4 review

Income statement

Statement of comprehensive income

Cash flow statement

Balance sheet

Statement of changes in equity

Notes

Parent company financial statements

Income statement

Balance sheet

Statement of changes in equity

Notes

Corporate matters

Governance and ownership

Risk management

Remuneration

Board of Directors

Board of Management

Delivering sustainable growth and profitability

With the transformation complete, ALK is now entering the next phase of its strategic development.

Cover picture: Collection of catkins from ALK's birch tree orchard in Post Falls, Idaho. Allergenic source materials are the main ingredients of ALK's allergy immunotherapy products.

After collection, the catkins are dried in special areas with carefully controlled environments.

Introduction

2020 highlights

ALK at a glance

Letter from the Chairman and CEO

2021 outlook

Management’s review • Annual report 2020 • ALK 4

2020 highlights

Succeed in North America

Complete and commercialise the tablet portfolio for all relevant ages

Consumer engagement and new horizons

Optimise for excellence

Other ALK launches

ITULATEK™ tablet for tree pollen allergy in Canada

Annual general meeting elects Anders Hedegaard as new Chairman of ALK’s Board

RAGWIZAX® for ragweed allergy is approved for children in Europe

ALK launches klarify digital platform in Denmark

ALK launches klarify digital platform in Ireland

COVID begins to impact business operations and clinical activities

New clinical Phase III trial for ALK’s house dust mite tablet initiated in China

ALK secures rights to market OTIPRIO™ in the USA

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

ALK announces drug discovery partnership with American biotech company X-Chem

ALK launches klarify digital platform in Slovakia

Q2 report: Revenue unchanged with tablet sales up 25% and EBITDA up 213%

RAGWITEK® for ragweed allergy is approved for children in Canada

Q1 report: Revenue up 10% with tablet sales up 38% and EBITDA up 49%

Full-year 2020 financial results: Revenue up 8% with tablet sales up 42% and EBITDA up 64%

ALK launches klarify ALK updates its full-year financial digital platform in the USA outlook to reflect improved earnings and cash flow as well as growth at the lower end of the guidance range

Q3 report: Revenue up 7% with tablet sales up 52% and EBITDA up 61%

Management’s review • Annual report 2020 • ALK 5

ALK at a glance

ALK key figures

Global presence

ALK is a global allergy solutions company with a wide range of treatments, products and services to meet the unique needs of allergy sufferers, their families and doctors. Headquartered in Hørsholm, Denmark, the company is listed on Nasdaq Copenhagen (ALKB:DC/OMX: ALK B)

International markets

North America

Revenue

11%

16%

Europe

Revenue

Established: Employees:

1923 ~2,500

73%

Development in revenue

SLIT-tablets (% growth in local currencies)**

DKK bn

Patients in treatment with ALK products*:

Markets:

Production sites

ALK’s unique manufacturing SCIT/SLIT-drops processes ensure its products meet required quality standards and represent a significant barrier to potential competitors, making them an important factor in maintaining ALK’s market position

Other

41 ~2m

3.5

3.3

3.0

2.9

2.9

2.6

2.4

+45%

+42%

2.3

2.3

2.2

+8%

+28%

The number of the most common global respiratory allergies covered by ALK's tablet portfolio:

Participated in clinical trials for the tablets:

2011

2012

2013

2014

2015

2016

2017

2018

2019

2020

5

23,000

** Includes certain milestone payments from partnerships in the period 2011 to 2016

  • Covering AIT and anaphylaxis

Management’s review • Annual report 2020 • ALK 6

ALK's business model

As a global allergy solutions company with a century of knowledge and expertise, ALK helps people to take control of their allergies and their lives.

Value created

Patients:

ALK’s tablet portfolio is helping to democratise AIT by covering the most common respiratory allergies, and bringing new treatment options to people without easy access to allergy specialists.

Raw materials

Active Pharmaceutical Ingredient (API) production

Allergens undergo thorough analysis, standardisation and quality control, so that naturally occuring variations are minimised, ensuring quality and consistency in the finished products.

Allergenic source materials, such as grass pollen and house dust mites, are the main ingredients of our products. Every year the company grows, collects or harvests several tonnes of allergens.

Doctors:

ALK helps allergists to drive better access and outcomes for all AIT-eligible patients, reaching out with support, disease information and treatment options.

Our people:

ALK is committed to a sustainable working life and keeps a constant focus on being a safe place to work for motivated and satisfied employees.

Key resources

Society:

ALK addresses profound societal challenges by producing medicines for the leading cause of lost productivity and lost work days. The company partners with payers and health authorities to advance registered, documented AIT products and is a signatory of the United Nations Global compact.

Our people and culture:

Around 2,500 highly-skilled employees live our cultural beliefs every day in their work to help more people with allergy.

Finished production

Production/natural allergens:

ALK’s biological medicines are derived from natural resources, such as pollen, which it harvests, standardises and quality controls at its own facilities. APIs are purified, then formulated for subcutaneous injections, sublingual drops or sublingual tablets.

Investors:

ALK works to create long-term value for its shareholders.

Scientific knowledge:

ALK continuously applies its scientific knowledge to help people take control of their allergies and their lives.

Allergy solutions for life

Sales and partnerships:

In addition to its own sales organisation, ALK partners for growth with leading specialty pharma companies worldwide. ALK is present in 41 markets, either directly or via partnerships.

R&D:

The completion of the tablet portfolio remains the primary focus of ALK’s R&D efforts. In addition, the company is conducting research into innovative solutions for high-impact allergic conditions – such as food allergies.

Packaging and distribution

Following careful quality control, the finished products are labelled, packaged and distributed.

Through information resources, services

People with allergies often endure a decade or more of symptoms before turning to AIT.

and products, ALK is working to support people with allergy early in their disease journey, smoothing the path to treatment.

Management’s review • Annual report 2020 • ALK 7

Megatrends shaping allergy

Most common chronic

disease in the world

Shift towards

evidence-based medicine

Food allergy

  • In Europe, authorities, prescribers and payers are increasingly turning to registered and documented products to treat allergies.

If you are allergic to a specific food, exposure may trigger an acute allergic reaction -

anaphylaxis - for which adrenaline auto-injectors are an effective rescue medication. In addition, recent advances in food

AIT hold promise of a better life for people with food allergy.

~500m people around the world are affected and consume products and services worth more than DKK 100 billion annually.# Management’s review • Annual report 2020 • ALK

Letter from the Chairman and CEO

2020 represented the final year of ALK’s strategic transformation, and our focus remained on the relentless execution of our goals. When we first announced this transformation, we said that we wanted to ‘fix and grow’ ALK by cleaning up past issues and establishing strong foundations to support growth. What 2020 clearly demonstrated is that we have been able to deliver on both of those promises, as a refocused ALK delivered 8% revenue growth while also proving resilient to an unprecedented global challenge, without which, growth would have been even stronger. Revenue growth was fuelled in the large part by a further spectacular increase in sales from our tablet portfolio of 42%, with the newly launched ITULAZAX® leading the way. Everyone at ALK can feel justifiably proud of the cultural and “ organisational transformation Throughout the transformation period, we have consistently overperformed relative to our promises, exceeding the cumulative sales forecast for 2018-20 by more than DKK 700 million, delivering EBITDA that was ahead of target, and registering significantly improved cash flow that was more than DKK 700 million ahead of plan. The positive results are also there to see across our four areas of strategic focus: ODACTRA®, although long-standing financial disincentives for prescribers, and the impact of COVID, have challenged commercial progress there. We have invested significantly to improve our patient engagement capabilities by developing our klarify digital ecosystem, which offers help and resources to the millions of people living with allergy so they can better understand and manage their condition. Importantly, klarify also enables us to mobilise patients to seek diagnosis and treatment in greater numbers. In addition to all of the above, we have advanced our site specialisation strategy and significantly pruned our portfolio, while also enhancing manufacturing efficiency, quality, and robustness. Together, these initiatives will secure long-term margin improvements. that they have contributed to over the past three years.

Anders Hedegaard,
Chairman of the Board

Tablets are now the undisputed growth engine of ALK, delivering an average growth of 37% over three years (CAGR). Meanwhile, the addition of ITULAZAX® to our range completed our mission to cover the five major most important respiratory allergies. In North America, we have established a new sales infrastructure and launched ACARIZAX®/

Continues

Management’s review • Annual report 2020 • ALK 9

Sustainable growth and profitability opportunities over the next five-to-10 years – such as an expanded offering in anaphylaxis, an entry into food allergy treatment, and research into innovative new treatments for high-impact allergic conditions. If we repeat our recent success in each of these areas over the coming years, we will establish a much larger ALK capable of continuously generating attractive shareholder returns. Having made the necessary, significant investments to transform ALK, we are now entering the next phase of the company’s development, where we must carefully work to sustain long-term growth, while also returning ALK to profitability. Our overall trajectory remains unchanged, because we are still convinced that the four priorities we established three years ago are the most critical to delivering future growth. Moreover, maintaining this continuity of focus will allow us to build on the foundations that we have now established, using our progress in each of these areas as a springboard from which to drive further growth. The commitment of our employees has been instrumental to delivering on the very ambitious targets we set when the strategy was first announced, and everyone at ALK can feel justifiably proud of the cultural and organisational transformation that they have contributed to over the past three years. Moreover, the work we have done together to strengthen ALK’s foundations has been critical to our ability to withstand the challenge of COVID, in response to which, not only did our employees swiftly implement our contingency plans and keep each other safe, but they also enabled ALK to maintain an uninterrupted supply of medicines for those who rely upon them. Tablets will remain our primary growth driver for the foreseeable future, and effective life-cycle management will be important to supporting their continued strong performance. This means expanding into new countries – such as China, and extending coverage to new patient groups – including children. Clearly, the US market still has largely untapped potential for ALK and will require much creativity and persistence before it fulfils our expectations but, as in other parts of the world, if we support our efforts with an effective commercial strategy by expanding the reach of klarify and establishing a broader, scalable sales model, and we back that up with excellence and robustness within our organisation, there is much more that we can achieve with the assets already at our disposal. Having made the necessary, significant investments to transform “ ALK, we are now entering the We continue to value the trust placed in us by patients, prescribers, and investors, and we will maintain our efforts to sustain and strengthen that trust wherever possible. By successfully executing the next phase of our development, which is designed to deliver sustainable growth and profitability, we can continue our progress towards becoming the 'go-to' allergy company. next phase of the company’s development, where we must carefully work to sustain long-term growth, while also returning ALK to profitability.

Carsten Hellmann,
President & CEO

Nevertheless, we have also taken care to incorporate initiatives that have the ability to accelerate our long-term development. Projects that may not make a significant contribution immediately, but which offer even further growth

Anders Hedegaard
Chairman of the Board

Carsten Hellmann
President & CEO

Management’s review • Annual report 2020 • ALK 10

2021 outlook

ALK expects growth across all sales regions in 2021, and revenue is projected to increase by 8-12% organically in local currencies, with the tablet portfolio expected to remain the key growth driver. growth negatively by approximately 1 percentage point.

2021 expectations

ALK expects broad-based growth across all sales regions. The mid-point of the projected revenue range assumes that sales in Europe will increase by around 10%. Sales in North America are expected to recover from the impact of COVID during 2021, growing in double digits, while sales growth in International markets is projected to temporarily slow to high single digits. This is mainly due to growth in Japan becoming more incremental following the extraordinarily high rates seen when Torii converted patients from an outgoing legacy product to the CEDARCURE™ tablet, and built up its inventories of CEDARCURE™ and MITICURE™.

  • Revenue
    • 8-12% organic growth – in local currencies
    • Growth across all sales regions

As a consequence of significant R&D cost delays from 2020 to 2021 due to the impact of COVID, and a gradual normalisation of capacity costs, operating profit (EBITDA) is expected to be close to that seen in 2020, despite revenue growth and an improved gross margin, attributable to tablet sales growth, and efficiencies.

ALK’s allergy solutions

Allergy can lead to asthma

Asthma is one of the world’s most common chronic childhood diseases. Preventing the progression of allergy into asthma would represent a major health breakthrough for millions of children.

Internet

The internet is the principal source of disease information for people with allergy: allergy is googled >100 million times a year. 1 in 10 AIT candidates receives treatment SLIT-tablets are the best documented AIT treatments ~50m Since 2001, 23,000 people have taken part in ALK’s clinical programmes. Its tablets are now the best documented AIT products in the world and are approved to the highest regulatory standards people with allergy are so seriously affected that they are potential candidates

The COVID effect

In 2020, the coronavirus pandemic and associated containment measures restricted the ability of people with allergy to visit clinics in many countries, increasing interest in telemedicine and home-based treatment options.

Symptoms of respiratory allergies

Respiratory allergies can affect both the upper and lower respiratory tract.

  • Upper respiratory tract – allergic rhinitis

    • Eyes
    • Nose
    • Mouth
    • Throat
    • Runny or blocked nose, itchy eyes, sneezing.
  • Lower respiratory tract – allergic asthma

    • Trachea
    • Bronchus
    • Lungs
    • Shortness of breath, narrowed airways, coughing, wheezing.

Climate change may increase number of people with severe allergy

Climate change means longer pollen seasons and more people suffering from severe allergies. Warmer weather is also causing ragweed to spread to new regions.

Biological products

ALK's SLIT-tablets have been developed from natural ingredients and are strongly protected thanks to unique biological manufacturing processes and standardisation procedures.

Digital engagement

Through ALK’s klarify digital platform, people with allergy are able to get information about their condition and seek treatment in greater numbers.

Included in asthma guidelines

The Global Initiative for Asthma, GINA, recommends sublingual AIT as a treatment option in patients with house dust mite- induced allergic asthma.

Complete tablet portfolio

80% of adults with respiratory allergic disease requiring AIT are now covered by ALK's portfolio of five SLIT-tablets which can be taken at home.

Urbanisation

Increasing migration to cities - especially in Asia - will further drive the prevalence of allergies such that ALK expects it to reach similar levels to Europe and the USA.# Management's review • Annual report 2020 • ALK

11 EBITDA

ALK’s working assumption is that the first half of 2021, and especially Q1, will continue to be impacted by COVID, especially in relation to allergy patients’ ability and willingness to visit healthcare professionals. This is likely to continue to impact the sales of treatments that rely on more frequent clinic visits, while sales of tablets are expected to remain resilient.

DKK 325-425 million Operating profit (EBITDA) – close to that seen in 2020, mainly due to COVID-related delays in R&D activities
Substantial, DKK ~150 million increase in R&D costs

Tablets, ALK’s single largest product category, will remain key to growth in 2021. ALK plans for strong, double-digit tablet sales growth in Europe and North America, while growth in Japan will be slower for the reasons stated above. Taking these factors together, ALK estimates that global tablet sales growth will exceed 20% in 2021, continuing their strong positive trajectory.

Free cash flow

Consequently, and as a result of the quarterly variations in 2020, fluctuations in revenue growth and earnings are likely from quarter to quarter during 2021.

DKK minus 200-300 million vs. DKK +56 million in 2020
Impacted by payments postponed from 2020

Revenue

In addition, ALK expects low single-digit sales growth from the remaining, non-tablet product portfolio, mainly driven by SCIT products, and double-digit sales growth from the Jext® adrenaline auto-injector. Organic growth is projected at 8-12% in local currencies. Discontinuations of legacy products are estimated to impact projected growth by around 2-3 percentage points.

The higher end of the projected revenue range assumes accelerated sales growth across all regions with tablets leading the way and faster market share gains, supported by a continuing regulatory transition towards evidence-based AIT products in key markets. The lower end of the revenue range incorporates pricing pressure, particularly in southern Europe, and/or more pronounced, ongoing negative effects from COVID.

Operating profit

Capacity costs will be influenced by a significant increase in R&D expenses in order to complete the clinical development of the tablet portfolio and gather further evidence for the tablets’ use in children, adolescents and to secure registrations in new geographies. R&D costs for 2021 are estimated at around DKK 650 million, a significant increase over 2020, of which, approximately DKK 100 million relates to activities that were originally scheduled for 2020 but were postponed due to the impact of COVID on patient recruitment for clinical trials.

Free cash flow

Free cash flow is expected to be negative, in the region of DKK 200-300 million. Free cash flow will be impacted by changes in working capital, including a one-off repayment of up to DKK 175 million in accrued rebates, which was originally scheduled for 2020, as well as a deadline extension for the settlement of around DKK 50 million related to 2020 tax payments for employees in Denmark. CAPEX is projected at approximately DKK 300 million with investments focused on streamlining the manufacturing footprint and further specialisation at ALK’s production facilities.

Forward-looking statements

This report contains forward-looking statements, including forecasts of future revenue, operating profit and cash flow, as well as expected business-related events. Such statements are, by their very nature, subject to risks and uncertainties, as various factors, some of which are beyond the control of ALK, may cause actual results and performance to differ materially from the forecasts made in this report. Without being exhaustive, such factors include, e.g., consequences of the global COVID pandemic, general economic and business-related conditions, including: legal issues, uncertainty relating to demand, pricing, reimbursement rules, partners’ plans and forecasts, fluctuations in exchange rates, competitive factors and reliance on suppliers. Additional factors include the risks associated with the sourcing and manufacturing of ALK’s products as well as the potential for side effects from the use of ALK’s existing and future products, as allergy immunotherapy may be associated with allergic reactions of differing extents, durations and severities.

Margins

The gross margin is expected to increase by 1-2 percentage points versus 2020, driven by efficiencies and higher sales – especially from tablets, with higher volumes absorbed by existing capacity. ALK will continue to allocate significant resources to the execution of its portfolio and site strategy, which designates each production facility as a centre of manufacturing excellence and is consolidating the number of active pharmaceutical ingredients used across the portfolio. These activities – in combination with increased sales and efficiencies that come from utilising higher-volume production lines – are expected to lead to substantial, long-term margin improvements. Sales and marketing activities are expected to gradually return to normal as the impact of COVID eases, particularly in the second half of the year. For the full year, costs are expected to rise in line with support for growth initiatives, although ALK will continue to seek to leverage its existing sales and marketing platforms to drive margin improvement.

Other assumptions

The outlook does not include any revenue from acquisitions, new partnerships or the in- licensing of adjacent products and services, nor does it include any sizeable payments related to M&As or in-licensing activities. The outlook is based on current exchange rates, resulting in a negative effect of approximately 1 percentage point on reported revenue growth and an immaterial effect on reported EBITDA. On this basis, ALK expects the operating profit (EBITDA) to be in the range of DKK 325-425 million, which is largely level with 2020's EBITDA of DKK 395 million.

Management’s review • Annual report 2020 • ALK
12 Performance
13 Financial highlights and key ratios
14 Sales and market trends
16 COVID-19: The defining challenge of 2020
17 Financial review of 2020
19 Q4 review

Management’s review • Annual report 2020 • ALK

13 Financial highlights and key ratios for the ALK Group*

DKK 2020 DKK 2019 DKK 2018 DKK 2017 DKK 2016 EUR 2020 EUR 2019
Amounts in DKKm/EURm Amounts in DKKm/EURm Amounts in DKKm/EURm Amounts in DKKm/EURm Amounts in DKKm/EURm Amounts in DKKm/EURm Amounts in DKKm/EURm
Income statement
Revenue 3,491 3,274 2,915 2,910 3,005 479
EBITDA 395 241 136 253 642 51
Operating profit/(loss) (EBIT) 150 (14) (17) (31) (50) 20
Net financial items (49) 101 (7) (42) (7) (7)
Profit/(loss) before tax (EBT) (103) (170) 2,385 (96) (80) (14)
Net profit/(loss) (122) (158) 2,341 (49) 101 (17)
Share capital 111 111 111 111 111 15
Shares in thousands of DKK 10 each 11,141 11,141 11,141 11,141 10,128 1,497
Share price, at year end 336.1 218.9 38.0 38.2 32 45.2
Net asset value per share 920 336.1 218.9 38.0 38.2 123.7
Average number of employees (FTE) 2,419 2,419 2,385 2,500 283 326
Key figures
Gross margin – % 58.1 57.8 56.0 56.4 58.1 58.1
EBITDA margin – % 11.3 7.4 4.7 8.7 21.4 11.3
Balance sheet
Total assets 5,563 5,495 4,865 4,958 4,799 748
Invested capital 2,664 2,759 2,968 2,864 2,353 358
Equity 3,153 3,176 3,179 3,290 2,875 424
Ratio analysis
Return on equity (ROE) – % (1.6) (5.3) (5.1) (1.6) (0.5) (1.6)
ROIC incl. goodwill – % 3.7 3.2 3.2 2.3 2.3 0.5
Pay-out ratio – % - - - - - -
Earnings/(loss) per share (EPS)
Earnings/(loss) per share (DEPS), diluted (356) (61) (46) (7) (2) (48.1)
Cash flow per share (CFPS) 5.7 3.4 2.5 0.3 0.3 0.8
Price earnings ratio (PE) (15.6) (15.9) (39.0) (15.9) (356) (15.6)
Share price/Net asset value (4.6) (4.6) (12.1) (3.4) (5.7) (4.6)
Cash flow and investments
Depreciation, amortisation and impairment 301 333 163 405 34 40
Cash flow from operating activities 1,092 1,092 405 333 132 147
Cash flow from investing activities (358) (245) (157) (199) (204) (48)
– of which investment in intangible assets (20) (147) (52) (126) (27) (3)
– of which investment in tangible assetss (26) (179) (46) (179) (3) (4)
CAPEX (300) (400) (300) (300) (300) (40)
Cash flow from financing activities (240) (26) (3) (3) (3) (32)
Total growth revenue 8 11 1 1 -6 8
Organic growth – % 8 11 1 1 (6) 8
Exchange rate differences (1) (2) (1) (1)
Acquisitions/divestments
– of which acquisitions of companies and operations
Free cash flow 56 (294) (745) 201 8 8
  • Management’s review comprises pages 1-46 as well as ‘Financial highlights and key ratios by quarter for the ALK Group’ on page 97
    ** Financial highlights and key ratios stated in EUR constitute supplementary information to the Management’s review. The exchange rate used in translating from DKK to EUR is the exchange rate prevailing on 31 December 2020 (EUR 100 = DKK 744) (31 December 2019: EUR 100 = DKK 747)

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Management’s review • Annual report 2020 • ALK

14 Sales and market trends

Overall revenue was DKK 3,491 million continuing constraints caused by COVID. Planned product discontinuations reduced growth by 4 percentage points, as numerous older SCIT and SLIT-drops products continued to be phased out in favour of documented, registered products. SCIT treatments rely on more frequent clinic visits, and were disproportionately affected by COVID since patients were either unable or unwilling to visit clinics and, in any case, capacity at many clinics – particularly in southern Europe – was significantly reduced. Revenue grew 8% organically in local currencies, and was in line with the most recent outlook, issued in November 2020. Planned portfolio rationalisations reduced growth by around 3 percentage points in 2020.# ALK Management's Review • Annual report 2020 • ALK 15

ALK also saw an impact on sales from COVID, particularly in the USA, where ALK estimates the total value of missed sales exceeded DKK 100 million. (3,274), which equates to organic growth of 8% in local currencies. Growth was driven by tablets, which is ALK’s largest single product category, and which proved resilient to the effects of COVID – in part due to its suitability as an alternative option for patients who were unable to continue with their usual treatments. Tablet sales grew by 42% with ITULAZAX® leading the way, while SCIT products were negatively affected by the impact of COVID as they are administered during visits to allergy clinics. The COVID- effect impacted sales in the USA in particular, where conditions were challenging, with significantly fewer patients visiting allergy specialists. Revenue growth was largely fuelled by sales of SLIT-tablets, which were up 40% at DKK 1,019 million (735). Sales benefited from the confluence of several factors: resilience to the impact of COVID versus alternative treatment options, the ongoing market shift in favour of evidence-based medicines, the benefits of an ALK sales excellence programme, and the ongoing roll-out of ITULAZAX®. Sales of other products were up 18% at DKK 211 million (179), driven by strong demand for the adrenaline auto-injector Jext®, which registered 42% sales growth and market share gains in key markets. Overall revenue increased in most markets, especially Germany, which delivered double- digit growth following a significant increase in tablet sales with a promising performance by ITULAZAX®. Furthermore, ALK became the first company in Germany to offer a complete product range for major allergens comprised solely of registered AIT treatments, reflecting (Comparative figures for 2019 are shown in brackets. Revenue growth rates are organic and stated in local currencies, unless otherwise indicated) Combined SCIT and SLIT-drops sales were down 9% at DKK 1,320 million (1,454). Of this, 6 percentage points related to product discontinuations, as well as the fact that Europe European revenue increased by 8% to DKK 2,550 million (2,368) despite some Continues Revenue by geography Growth Revenue by geography Revenue by product line Growth Revenue by product line Europe International markets North America SCIT/SLIT-drops Other SLIT-tablets DKKm 2020 (l.c.) 2019 DKKm 2020 (l.c.) 2019 11% (7%) 13% (15%) Europe 2,550 573 8% -10% 58% 8% 2,368 669 SCIT/SLIT-drops SLIT-tablets 1,673 1,370 448 -7% 42% -4% 8% 1,818 973 North America Int'l markets Overall revenue 73% (73%) 48% (55%) 16% (20%) 368 237 Other products Overall revenue 483 3,491 3,274 3,491 3,274 2020 (2019) 2020 (2019) 39% (30%) Management’s review • Annual report 2020 • ALK 15

An ongoing market shift in favour of North America

Full-year sales of tablets in the region grew by 4% to DKK 85 million (85), driven by Canada as US sales stagnated. In volume terms, tablet uptake in North America increased by 28%, but market-building tactics such as rebates and coupons – essential to establishing any new medicine in this region – reduced effective sales prices. Sales of bulk allergen extracts were down 5% at DKK 275 million (306), while sales of diagnostics and other products decreased 19% to DKK 213 million (278) – mainly due to COVID reducing sales of non-allergy related life science products and the use of PRE-PEN® in hospitals. ALK became the first company in Germany registered, evidence-based products, which was further facilitated by a change to the fee model, mitigating unintended disincentives for doctors to prescribe tablets. In France, overall sales were unchanged as growth in tablet sales was offset by lower SLIT-drops sales. However, ALK remains the market leader in terms of the number of patients receiving treatment. Meanwhile, sales in Spain were also impacted by COVID, while the challenging conditions in Italy were further exacerbated. The fallout from the COVID pandemic made market conditions in North America challenging, especially in the USA, and suppressed sales across the portfolio. A major influence on this was patients’ ability and willingness to visit allergy clinics, while a further challenge came from the fact that many clinics were running at a reduced capacity. At one point, during Q2, ALK estimated that up to half of US allergy clinics were fully or partially closed, while those that were open were seeing significantly fewer patients. to offer a complete product “ range for major allergens comprised solely of registered AIT treatments. Overall, market conditions were largely stable, and there were no notable changes affecting the pricing and reimbursement of AIT products, although the risk of pressure in southern Europe remains. In consequence, revenue in North America was down 10% organically in local currencies to DKK 573 million (669). This was despite some improvements in H2, particularly in sales of tablets and bulk SCIT products.

International markets

Revenue from International markets was up 58% in local currencies at DKK 368 million (237) as ALK’s largest markets in the region, Japan and China, resisted and rebounded from COVID, respectively. Revenue in Japan from product supply and sales royalties grew by 80%. ALK’s partner Torii continued to successfully build the 5-year total revenue by geography 5-year total revenue by product line Europe North America SCIT/SLIT-drops Other SLIT-tablets DKKm DKKm 3,500 3,000 2,500 2,000 1,500 1,000 500 3,500 3,000 2,500 2,000 1,500 1,000 500 0 0 2016 2017 2018 2019 2020 2016 2017 2018 2019 2020 market for tablets and MITICURE™ sales were up strongly, while sales of CEDARCURE™ were boosted by the conversion of patients from an outgoing legacy product. Revenue in Japan also benefited from the effects of stock-building by Torii, which provided an extraordinary boost to revenue in Q3 and Q4. ALK sales in China grew by 28%, while growth was also recorded in south-east Asia, Turkey, and Israel. International markets Management’s review • Annual report 2020 • ALK 16

COVID-19: e defining challenge of 2020

by patients at home – proved extremely resilient. Meanwhile ALK made good use of its digital engagement platforms to support healthcare professionals and patients. e emergence of COVID, its global spread, and subsequent measures to contain it, all had a significant effect on ALK’s business in 2020. Regions where COVID first took hold, such as China and later, Europe, were the first to stage a market recovery, meaning that Once the seriousness of the pandemic became clear, in Q1, ALK took immediate action to protect staff, and invoked contingency measures to safeguard business continuity and maintain the supply of ALK products for doctors and their patients. As a result of these measures, ALK’s inventories of both supplies and finished products remained robust throughout the year. patients once again became able to visit healthcare professionals without significant limitations, although, in some countries – notably in southern Europe – capacity was still constrained to some extent. ALK’s working assumption is that the first half of 2021, and especially Q1, will continue to be somewhat impacted by COVID, especially in relation to allergy patients’ ability and willingness to visit healthcare professionals. This is likely to continue to impact treatments that rely on more frequent clinic visits, while tablets are expected to remain resilient. ALK’s COVID task force In February 2020, just a few weeks after reports began appearing of a new coronavirus emerging in China, ALK convened the first meeting of its COVID task force. Its purpose was to anticipate and mitigate the potential consequences of the virus, should it spread further, and to promote global guidelines for the ALK organisation on managing the situation, including initiatives to maintain a sense of togetherness among employees working from home during lockdowns. The impact on sales was greatest for those products that are typically delivered in an allergy clinical or hospital, such as SCIT products, and in specific markets, such as the USA, where it is estimated that the total value of missed sales exceeded DKK 100 million. Outside of the USA, sales of ALK’s SLIT- tablets – which can be self-administered COVID also had a significant effect on ALK’s clinical development activities, particularly on patient recruitment which, at one point, was placed on hold for all trials. The task force’s approach was both proactive in that it developed a wide-ranging contingency plan to safeguard both employees and the ongoing supply of medicines, and conservative in that it applied a ‘safety first’ principle to all the scenarios it considered. One example of this was the construction of a separate, temporary staff restaurant in Denmark solely for the use of manufacturing staff. The task force served a dual role in overseeing business continuity in Denmark, and offering guidance to those coordinating contingency measures in other countries, which were tailored to ensure compliance with the differing local situations and regulations. Two critical successes of ALK’s actions were that, despite many of its employees being quarantined at various times, throughout 2020, there was no uncontrolled chain of infections within the company and that the supply of ALK's products remained uninterrupted throughout the year. The task force will continue to meet in 2021 until the threat of COVID subsides. Continues Management’s review • Annual report 2020 • ALK 17

Financial review of 2020

(Comparative figures for 2019 are shown in brackets.# Management’s review • Annual report 2020 • ALK 18

Revenue growth rates are organic and stated in local currencies, unless otherwise indicated) 58% (58%), and reflected changes in the 2020 guidance history product mix, increased sales – especially from tablets – but also lower sales of legacy products in Europe and significant costs associated with compliance efforts to secure robustness in product supply, as well as the implementation of the product and site strategy. Increased shipments of tablets at a lower gross margin to ALK’s partner for Japan lowered reported gross margin by approximately 1 percentage point.

2020E 2020E

12 August outlook 2020E 5 November outlook 5 February outlook 2020 Actual
DKK 2020 revenue increased organically by 8% in local currencies to DKK 3,491 million (3,274) and was negatively impacted by COVID, predominantly in the USA. Exchange rate fluctuations impacted reported revenue growth negatively by 1 percentage point. The divestment of the US veterinary business in late 2019 reduced reported growth by approximately 0.5 of a percentage point. Revenue +8-12% organic Lower end of +8-12% organic
EBITDA 200-300m ~(300)m 300-350m
Free cash flow

Capacity costs decreased 1% in local currencies to DKK 1,877 million (1,922). R&D expenses increased by 11% in local currencies to DKK 515 million (466) in support of clinical trials, although this was significantly lower than expected following delays to clinical activities due to the COVID pandemic. Particularly affected was the recruitment of patients for clinical trials. Sales and marketing expenses decreased organically by 5% in local currencies to DKK 1,125 million (1,210), reflecting savings as a consequence of COVID restricting sales and marketing activities in many markets, and operational leverage of ALK’s commercial activities. Administrative expenses decreased 4% in local currencies to DKK 237 million (246). Cost of sales increased 7% organically in local currencies to DKK 1,463 million (1,382). The gross profit of DKK 2,028 million (1,892) yielded a gross margin of

Continues

Revenue

DKKm %
3,500 30
3,000 25
2,500 20
2,000 15
1,500 10
1,000 5
500 0
2016 2017 2018

Gross profit

DKKm %
3,500 80
3,000 70
2,500 60
2,000 50
1,500 40
1,000 30
2016 2017 2018

Research and development

DKKm %
500 20
400 16
300 12
200 8
100 4
0 0
2016 2017 2018

Sales, marketing and administration

DKKm %
1,500 70
1,200 60
900 50
600 40
300 30
0 20
2016 2017 2018

Revenue

DKKm %
30 16
20 12
10 8
0 4
-10 0
-20 -4
2016 2017 2018

EBITDA (operating profit before depreciation and amortisation) increased 64% to DKK 395 million (241) and was better than expected, reflecting savings and delayed R&D expenditure due to COVID. Exchange rates did have a small negative impact on operating profit. Cash flow from investment activities was DKK minus 245 million (minus 157) mainly relating to upgrades to legacy production and the build-up of capacity for SLIT-tablet production. Equity totalled DKK 3,153 million (3,176) at the end of the year, and the equity ratio was 57% (58%). Net financials were a loss of DKK 49 million (loss of 17) mainly relating to net interest expenses and currency fluctuations on intercompany loans. Tax on the profit totalled DKK 76 million (19) and net profit was DKK 25 million (a loss of 50). At the end of 2020, ALK held 212,873 of its own shares or 1.9% (2.2%) of the share capital. Free cash flow was positive at DKK 56 million (minus 25), which was better than expected due to higher earnings. Cash flow from financing activities was DKK minus 62 million (minus 57), mainly relating to minor repayments of borrowings and the settlement of incentive programmes. Cash flow from operating activities was positive at DKK 301 million (132) mainly as a consequence of the increased EBITDA. Furthermore, cash flow was negatively impacted by changes in working capital as a consequence of the company’s growth momentum. At the end of 2020, cash and marketable securities totalled DKK 298 million (316). In addition, ALK has an unused credit facility of DKK 600 million which runs until 2022.

EBITDA

DKKm %
1,000 25
800 20
600 15
400 10
200 5
0 0
2016 2017

Management’s review • Annual report 2020 • ALK 19

Q4 review (Comparative figures for 2019 are shown in brackets. Revenue growth rates are organic and stated in local currencies, unless otherwise indicated)

• Total revenue was up 16% organically in local currencies at DKK 991 million (883). Portfolio rationalisations reduced growth by 3 percentage points. In addition, reported growth was negatively impacted by 4 percentage points due to exchange rate fluctuations

• In North America, Q4 revenue was down 2%, which nevertheless reflected a rise in demand after the very challenging market conditions caused by COVID in Q2 and Q3. Tablet sales in the region were up 37%, while sales of bulk allergen extracts (SCIT) decreased 1%. Sales of other products and services declined 13% on the impact of COVID. In December, RAGWITEK® was approved for the treatment of moderate-to-severe ragweed pollen allergy in children age five and older in Canada.

• In Europe, revenue was up 17%, driven by strong uptake of the tablets, for which sales grew 54%. Combined sales of SCIT and SLIT-drops were down 2%, reflecting product discontinuations, patients switching to tablets and COVID-related constraints on clinic visits. Sales of other products increased 18% on high growth in sales of the Jext® adrenaline auto-injector, which were up 45%.

• Combined SCIT and SLIT-drops sales were down 2% at DKK 477 million (501) general inventory stocking at wholesalers ahead of 2021 was observed in selected markets.

• Sales of other products declined 1% to DKK 105 million (113)

Strong Q4 delivers results in line with latest outlook

Some ALK finished 2020 with a strong final quarter, registering 16% in organic revenue growth, fuelled by very strong tablet sales growth of 55% during the peak season for AIT treatment initiations. COVID continued to impact patients’ ability and willingness to visit clinics, especially in the USA and in selected European markets, but the overall impact of the pandemic was reduced.

Tablet sales grew by 55% to DKK 409 million (269) with high, double-digit growth in all sales regions

Income statement

Revenue by geography Q4 Growth Q4 2020 Q4 2019 DKKm 2020 (l.c.) DKKm 2019
Revenue 16% 991 883 734 638
Europe 17% 412 368
International markets 46% 155 149
North America -2% 102 173
Revenue by product line Q4 Growth Q4 2020 Q4 2019 DKKm 2020 (l.c.) DKKm 2019
Revenue 16% 991 883 579 515
SCIT/SLIT-drops -2% 477 501
SLIT-tablets 55% 409 269
Other -1% 105 113
Amounts in DKKm Q4 2020 Q4 2019 DKKm 2020 (l.c.) DKKm 2019
Revenue 991 883
Cost of sales 412 368
Gross profit 579 515
Gross margin 58% 58%
Research and development expenses 173 149
Sales and marketing expenses 102 155
Administrative expenses 72 65
Other operating items, net 0 (9)
Operating profit/(loss) (EBIT) 17 (10)
Net financial items (4) (5)
Profit/(loss) before tax (EBT) 14 (14)
Tax on profit 15 (15)
Net profit/(loss) (31) (29)
Revenue by geography 2020 (2019)
Europe 734 (638)
International markets 155 (149)
North America 102 (173)
Revenue by product line 2020 (2019)
SCIT/SLIT-drops 477 (501)
SLIT-tablets 409 (269)
Other 105 (113)
%
Revenue 16%
-2%
46%
16%
10%
(8%)
11%
(13%)
17%
(20%)
41%
(30%)
16%
(14)
74%
(72%)
48%
(57%)
16%

Operating profit before depreciation and amortisation (EBITDA)

DKKm %
64 48

Management’s review • Annual report 2020 • ALK 20

In International markets, revenue grew by 46%, fuelled by the strong uptake of tablets in Japan including planned, advance stocking by Torii ahead of 2021, which provided an extraordinary boost to revenue during the quarter. Capacity costs increased 11% in local currencies. Sales and marketing expenses increased 7% in local currencies as ALK increasingly focused on its digital platforms while COVID restricted other promotional activities. R&D expenses increased by 21% in local currencies, however, COVID continued to hinder the recruitment of patients for clinical trials. During Q4, ALK saw a clear impact on its clinical development activities from COVID. The anticipated new timelines for ALK's key clinical trials are detailed below. EBITDA of DKK 64 million (48) was in line with the most recent expectations, reflecting higher sales, as well as savings and delayed R&D expenditure due to COVID. Gross margin was 58% (58%), reflecting changes in the product mix, higher tablet sales, and increased lower-gross margin shipments to Japan, but also significant costs for compliance efforts to solidify robustness in product supply, as well as the implementation of the product and site strategy.

Original Expected Trial completion completion Comments
HDM SLIT-tablet Registration trial China 2021 2022
HDM SLIT-tablet Paediatric allergic rhinitis Europe/North America 2022 2023
HDM SLIT-tablet Paediatric allergic asthma Europe/North America 2022 2022
Tree SLIT-tablet Paediatric allergic rhinitis Europe/Canada 2023 2023

After collecting, drying and sieving catkins to release pollen, the lipid layer is removed to prepare the pollen for protein extraction

Management’s review • Annual report 2020 • ALK 21

Strategic transformation 22

Strategy update 26

Succeed in North America 27

Complete and commercialise the tablet portfolio for all relevant ages 29

Consumer engagement and new horizons 30

Optimise for excellence 31

Lead the way – people and planet 32

Medium-term financial ambitions

Management’s review • Annual report 2020 • ALK 22

Strategy update

company’s improved consumer engagement capabilities not only offer help and resources to millions of people with allergy, they also help mobilise consumers towards AIT treatment.# Management's review

Annual report 2020 • ALK 23

Finally, through investments in quality upgrades, ongoing portfolio reduction and its site specialisation strategy, ALK has taken significant steps in improving manufacturing quality, efficiency and robustness. In December 2017, ALK announced a three-year strategic transformation to establish a broader presence in the allergy market and stimulate a new period of sustained growth. Over the past three years, the company has pursued a series of initiatives under four areas of focus: succeed in North America, complete and commercialise the tablet portfolio for all relevant ages, patient engagement and adjacent business opportunities, and optimise and reallocate resources towards growth initiatives. On the next page is a summary of what has been achieved in each of these focus areas.

Continues The USA still holds considerable potential for ALK’s tablets despite long-standing financial disincentives for allergists to prescribe these products. ALK’s approach will be, with creativity and persistence, to continue establishing new and broader sales channels with the aim of gradually unlocking the potential of this market. Meanwhile, progress on the other three priorities has been significant. The SLIT-tablets now cover five of the most common global respiratory allergies and have become ALK’s growth engine, delivering an average growth of 37% over the past three years (CAGR). The Over the past three years, ALK has pursued a series of initiatives under “ four areas of focus. Right: Tablets will remain ALK's primary growth driver for the foreseeable future and will be the focus of efforts to extend coverage to new patient groups – including children

Key achievements 2018-20

Financial results exceed expectations Infrastructure established & ACARIZAX®/ODACTRA® launched Commercial strategy tested & rolled out, execution challenged by market barriers Initial tablet prescriber base established
Succeed in North America Accumulated three-year revenue >DKK 700 million better than expected*
Complete and commercialise tablet portfolio Accumulated three-year EBITDA ~DKK 800 million better than expected Tablets now launched for all five major respiratory allergies Tablets as primary growth drivers with 37% growth (3-year CAGR)
Patient engagement and adjacencies Accumulated three-year free cash flow >DKK 700 million better than expected Digital platforms rolled out in six markets with hundreds of thousands of users US adrenaline strategy in place Small-scale consumer division launched
Optimise and reallocate Ongoing quality and robustness upgrades for legacy products New site strategy implemented Portfolio rationalisation: more than 300 products phased out
(Actual: DKK 9.7 billion) (Actual: DKK 772 million) Ongoing clinical programme for paediatrics/adolescents, asthma, new market entries: on track pre-COVID Life-cycle management of core legacy portfolio: ~3,500 regulatory updates
Cultural transformation in progress
  • Based on the original 2018 outlook of DKK 2.7 billion and 10% growth from 2019 onwards

Continues

Management’s review • Annual report 2020 • ALK 24

Delivering sustainable growth and profitability

ALK’s overall strategy remains unchanged, and is still anchored in the same four areas of focus, albeit with minor adjustments to some of the names to reflect the necessary steps to achieving profitability: succeed in North America, complete and commercialise the tablet portfolio, consumer engagement and new horizons, and finally, optimise for excellence. With the transformation complete, ALK is entering the next phase of its development. The challenge now is to use what has been achieved as the launchpad for future success as ALK seeks to become the allergy company by extending its leadership in respiratory allergy, expanding its position in anaphylaxis, establishing a presence in food allergy, and pursuing new innovations through research. In addition, some longer-term initiatives have been introduced which, as they develop, are designed to provide the additional impetus to accelerate ALK towards its longer-term aspiration of becoming a global allergy leader. The emphasis for the period 2021-23 is on achieving sustainable growth and increasing profitability following the significant investments made to successfully deliver the transformation.

Management’s review • Annual report 2020 • ALK 25

Focus areas during 2021-23

Succeed in North America Complete and commercialise tablet portfolio Consumer engagement and new horizons Optimise for excellence
Sustainable growth and profitability Sales growth of 10% or more Improving EBIT
ALK seeks to become the allergy company by extending its leadership in respiratory allergy, expanding its position in anaphylaxis, establishing a presence in food allergy, and pursuing new innovations through research. Establish broader, scalable sales model for tablets Leverage digital platforms to mobilise patients Drive sales recovery across wider non-tablet product portfolio Complete paediatric development and commercialise across ALK’s markets Sustain commercial momentum of tablets (expand breadth and depth of prescriber base) Complete clinical development and prepare for launch in China, leverage clinical data to enter new markets From consumers to AIT patients – develop and leverage digital ecosystem for consumers, patients and HCPs Drive growth of Jext® in EU and prepare next generation global adrenaline solution Develop innovative new treatments for high-impact allergic conditions, including food allergies Maintain quality excellence and IT robustness Complete portfolio rationalisation and site specialisation Maintain and upgrade core legacy products Lead the way – people and planet

Continues

Management’s review • Annual report 2020 • ALK 26

Succeed in North America

Succeeding in North America – and particularly the USA, which is the world’s largest market for pharmaceuticals – continues to be an important priority for ALK, despite the setbacks caused by the COVID pandemic.

Short-term objectives
Increase total sales in North America
2021 target: ≥+10% p.a. (2020 status: DKK 573m)

ALK will continue to invest in its strategy for North America, developing and adapting its platform there to mobilise allergy patients and deliver accelerated tablet sales, and securing paediatric and adolescent indications for ACARIZAX®/ODACTRA® and RAGWITEK®, as well as introducing other prescription allergy solutions.

How COVID impacted the US AIT market
2021 target: 20,000 (2020 status: ~5,800)

COVID made its first big impact in the USA in March 2020, when a nationwide lockdown was ordered after infection rates spiked. The timing coincided with the start of the spring allergy season which is the peak season for treatment initiations in the USA, when the onset of seasonal allergy symptoms usually prompts a rush to allergy clinics.

Central to this approach will be the further evolution of digital engagement tools, first mobilising patients to seek treatment for their allergies, and second, providing a framework that connects them with ever more healthcare professionals who are willing and able to prescribe ALK products. But by now, many clinics were closed, and where they remained open, patients were either unable or too fearful to visit them such that, during Q2, in-person visits to doctors' offices fell by around 70% versus the same period in 2019.

Secure paediatric and adolescent indications for ACARIZAX®/ODACTRA® and RAGWITEK®

This severely limited the number of new treatment initiations across ALK’s portfolio since, even for the tablets, US labelling requires that first doses should be administered under medical supervision. As a result, ODACTRA® new patient initiations fell by more than 50% between March and May when compared with pre-COVID levels. ALK responded with a range of measures – supporting allergists by phone and online, ramping up direct-to-consumer communications, offering direct mail-outs of maintenance treatment to those already on tablets, and introducing digital tools to support customers, patients and its own sales organisation – so that, by Q4, ODACTRA® new patient initiations were exceeding those of Q1.

Finally, ALK will continue to maintain and promote its bulk allergens and other products that underpin its relationship with, and commitment to, existing customers. These products represent an important commitment to offering a full range of allergy products and treatment options and will continue to play a role in delivering value growth in the region for ALK.

2021 target: RAGWITEK® paediatric approval in the USA, ACARIZAX® adolescents approval in Canada (2020 status: RAGWITEK® paediatric approval in Canada)

By the end of the year, capacity in clinics had returned to around 80% of normal and ALK reverted to a mix of traditional and virtual sales methods. Despite the constrained capacity at clinics during 2020, ALK still saw an overall year-on-year increase in tablet sales volumes and saw further encouraging signs in December, when ODACTRA® prescription volumes substantially outpaced those from the same period in 2019.

Management’s review • Annual report 2020 • ALK 27

Complete and commercialise the tablet portfolio for all relevant ages

The tablet portfolio now covers all five of the allergies that were targeted under this programme – house dust mite, grass, tree, ragweed and Japanese cedar. These tablets remain ALK’s core assets and further development will focus on consolidating and expanding the leadership they give ALK in respiratory AIT. To achieve this, ALK will extend the reach of these products to cover new geographies and new patient groups – such as children and adolescents, and strengthening the evidence for their use in allergic asthma.# Management’s review • Annual report 2020 • ALK 28

What is critical, is that each of these steps goes hand in hand with the ability to successfully commercialise each expanded opportunity, and to fully realise the market potential of these assets.

The transition towards registered products in Germany

The AIT market in Germany has undergone a major transformation over the past decade, as a combination of key opinion leader-recommendations, tighter regulation, and revised rules on reimbursement and the doctors' fee structure have taken effect. Together, these changes have resulted in a market that is now much more favourable for documented, registered allergy treatments, and have resulted in a reduction from more than 6,000 prescription AIT products available in the mid-2000s, to fewer than 200 today.

In addition to key allergy opinion leaders, this shift has had vocal support from Germany’s medical insurance funds, who are keen to see evidence of tangible medical benefits from the treatments they offer reimbursement for. From the pharmaceutical industry’s side, ALK has been a leader of the move towards registered treatments, from the thorough clinical documentation that accompanied its development of the SLIT-tablet portfolio, to the clinical development work it has undertaken in support of key legacy products. To the extent that, in July 2020, ALK became the first company in Germany to offer a complete product range for major allergens comprised solely of registered AIT treatments, which account for more than 90% of all AIT treatments currently administered.

SLIT-tablet portfolio covers five of the most common respiratory allergies

ALK’s SLIT-tablet pipeline

Phase I Phase II Phase III Filing Marketed
GRAZAX® Europe 2007
GRASTEK® North America
GRAZAX® International markets*
RAGWITEK® North America 2014
RAGWIZAX® Europe & Int'l markets
RAGWIZAX® / RAGWITEK® Europe & NA ***
ACARIZAX® Europe 2016/17
ACARIZAX®/ODACTRA® North America
MITICURE™ Japan** 2017/18
ACARIZAX® International markets*
ACARIZAX® China ****
ACARIZAX®/ODACTRA® Europe & NA
ACARIZAX®/ODACTRA® Europe & NA
ODACTRA® North America
CEDARCURE™ Japan** 2018
Adults and children – Allergic rhinitis (grass) Adults and children – Allergic rhinitis (grass) Adults and children – Allergic rhinitis (grass) Adults – Allergic rhinitis (ragweed) Adults – Allergic rhinitis (ragweed) Children – Allergic rhinitis (ragweed) Adults – Allergic rhinitis and allergic asthma (HDM) Adolescents – Allergic rhinitis (HDM) Adults – Allergic rhinitis (HDM) Adults and children – Allergic rhinitis (HDM) Adults and children – Allergic rhinitis (HDM) Adults – Allergic rhinitis (HDM) Children – Allergic asthma (HDM) Children – Allergic rhinitis (HDM) Children – Allergic rhinitis (HDM) Adolescents – Allergic rhinitis (HDM) Adults and children – Allergic rhinitis (Japanese cedar) Adults – Allergic rhinitis (tree: birch family) Adults – Allergic rhinitis (tree: birch family)
GRAZAX® X X X
GRASTEK® X
GRAZAX® X X
RAGWITEK® X
RAGWIZAX® X X
RAGWIZAX® / RAGWITEK® X X
ACARIZAX® X X
ACARIZAX®/ODACTRA® X X
MITICURE™ X X
ACARIZAX® X
ACARIZAX® X
ACARIZAX®/ODACTRA® X X
ACARIZAX®/ODACTRA® X
ODACTRA® X
CEDARCURE™ X X X

~23,000 people participated in clinical development of the tablets which saw 21 Phase III trials.

  • Licensed to Abbott for south-east Asia and Seqirus for Australia/ New Zealand
    ** Licensed to Torii for Japan
    *** Approved in Europe
    **** Already marketed in selected markets

Consumer engagement and new horizons

Over the recent years, ALK has developed a suite of digital tools and platforms as part of its klarify- branded ecosystem for consumers, so that those most suitable for AIT can gain smoother access to a definitive diagnosis and appropriate treatment. Over the next few years, ALK will leverage these assets to further engage with and mobilise people with allergy. Through this engagement, ALK aims to not only promote a wider understanding of allergy, its causes and potential treatments, but also to more easily connect those suitable for treatment with AIT with a competent healthcare professional who can help them.

The previous priority of seeking adjacent business opportunities has been broadened to encompass not just business development and partnership opportunities, but also the work of ALK – through its own research and development – to formulate and refine innovations outside the current respiratory AIT niche in order to establish a broader and more robust presence in the wider allergy segment over the long term. One example of this is the goal of entering the US market with an adrenaline auto-injector that is both affordable and competitive, with a submission to the US FDA no later than 2024. Another is a platform programme to enter the food allergy treatment market, which is an area of significant unmet medical need.

How klarify is connecting with consumers

In Q4, in the USA, ALK added a ‘speak to a doctor’ option to its klarify and branded digital engagement platforms, and saw more than 40,000 US consumers take its digital ‘allergy-control’ test. This allows consumers to test whether their allergy is under control and offers them the option of an online consultation with a qualified allergist who can either issue an appropriate prescription, or refer them for a diagnosis to identify their specific allergy and, potentially, treatment with ALK’s SLIT-tablets. By engaging US consumers in this way, and identifying those who need more help and connecting them with allergists, ALK is connecting the dots for people suffering in silence with their allergy by offering them a convenient, and digitally-driven consumer journey.

Finally, ALK will continue to identify and explore the potential addition of new products and services to its portfolio through an active programme of business development and thorough due diligence. In essence, ALK aims to become better at clarifying the journey and hand-holding eligible treatment candidates along the path from curious consumer, to AIT patient. This type of service is an important way of offering personalised, professional advice on allergy, while helping people with allergy to navigate the often confusing path to a clear diagnosis and treatment. In addition, it ensures referrals are directed to allergists who are willing and able to prescribe the full range of allergy treatment options – from symptomatics, to allergy shots (SCIT) and, importantly for ALK, SLIT-tablets.

Short-term objectives

  • Mobilise consumers globally via digital engagement
  • Progress R&D innovation projects

2021 targets

2021 target 2020 status
Increase global tablet sales in strong double digits annually >20% DKK 1,370m
Clinical development for paediatric use and geographic expansion Progress as planned COVID-affected
Food: Prepare for clinical development 250,000 ~200,000
Anaphylaxis: Decide on US development pathway Research
2021 target 2020 status
Progress R&D innovation projects Meet project milestones On track

While the regulations covering such offerings differ from country to country, ALK is developing a standardised methodology that can be adapted to local requirements. For example, in Germany, ALK is offering users of klarify the option of speaking to a facilitator who can guide them through the process of obtaining a diagnosis and contacting a healthcare professional who is able to prescribe an appropriate treatment for their allergy.

2021 target 2020 status
Food: Prepare for clinical development Development

Management’s review • Annual report 2020 • ALK 30

Optimise for excellence

The fourth focus area will see ALK continue its already established programme of portfolio rationalisation, manufacturing site specialisation, and other initiatives designed to ensure regulatory compliance, robustness of supply, and to improve overall quality and efficiency. This includes an initiative to upgrade and safeguard ALK's core legacy products in Europe, which will continue.

Short-term objectives

  • Contribute to improved overall gross margin by continuing to prune the portfolio and optimising manufacturing operations
  • Upgrade product documentation and facilities to sustain long-term portfolio of legacy products
  • Driving sales excellence across ALK

2021 target

2021 target 2020 status
Contribute to improved overall gross margin +1-2 p.p. 58%
No quality-related major interruptions to supply None None

In addition, ALK will continue its work to drive organisational excellence and to further embed the cultural progress delivered by the transformation effort. Efforts to improve the operational leverage of ALK’s commercial activities will also continue.

The completion of the tablet portfolio and the rationalisation of ALK's legacy portfolio over recent years has significantly standardised the range of products sold by the company. By 2018, this increased standardisation allowed ALK to begin an initiative – known internally as RISE – to significantly strengthen its sales and marketing execution. A 'better practice' analysis was carried out of the company’s approach to preparing, conducting, and following up on customer calls, as well as the materials used to support them. The results of this, together with input from external benchmarking, were used to create and launch a global sales and coaching model for best practice customer interactions. In addition, marketing tools began to be developed with this framework in mind, maximising the ease and impact of local adaption. Behind the scenes, a digital ecosystem of support tools is being implemented, along with a single, global customer relationship management (CRM) system.

All of this has resulted in improved ways of working within the Sales & Marketing organisation, and has established a more uniform approach to selling across ALK, as well as better leveraging of tools and resources. Meanwhile, ALK’s staff have welcomed the training they receive as a valuable investment in their future. The RISE model is now in place across Europe and will be expanded to North America, Russia and China in 2021.# Management’s review

Annual report 2020

Lead the way – people and planet benefit from a strong framework of support

Becoming the allergy company will require ALK to lead the way in many areas, not just scientifically and commercially, but also in the way it develops its people and organisation and in its approach to sustainability. for leadership and talent development. Central to this will be ALK’s cultural beliefs which encourage open dialogue, honest feedback, and strong cross-organisational cooperation. In addition, a renewed commitment to sustainability will see ALK establish a business model that will improve access to allergy care and deliver on ALK’s wider commitments to the environment, sustainability and governance. ALK’s efforts in each of the four focus areas will therefore be underpinned by a ‘platform’ which addresses organisational agility and sustainability. Organisational agility initiatives will ensure that ALK’s future growth is enabled by highly engaged and motivated employees who

Continues Short-term objectives Global talent development programme: ASPIRE New dialogue tool to support organisational development Sustainability progress*
2021 target 2021 target 2021 target 2021 target
Implement (2020 status: N/A) Implement (2020 status: N/A) Meet ALK's goals (2020 status: See *)
  • For a detailed breakdown of ALK’s sustainability performance and goals, please refer to the ESG (Environmental, Social, and Governance) key figures overview on page 36 of this report and the sustainability report available at www.alk.net/sustainability

From EBITDA to EBIT for medium-term financial ambitions

ALK will use EBIT – Earnings Before Interest and Taxes – as the prime indicator of the company’s long-term profitability aspirations. Hence, ALK’s long-term financial indications for operating profit are stated as EBIT rather than the previously applied EBITDA. The change reflects an increasing focus on the underlying earnings generation of the company and the fact that the next phase of the strategy is one of stable capital expenditure.

Medium-term financial ambitions

ALK's updated range of financial indicators for the next phase of its strategic development are:

  • An ALK capable of delivering sustainable revenue growth of 10% or more annually
  • An ALK capable of returning its business to profitability, and ramping up its EBIT-margin to approximately 25% in 2025

These indications include costs for the development of food allergy immunotherapy solutions and new approaches to the treatment of severe allergic conditions. They also assume:

  • A gradually improving gross margin driven by higher sales and greater efficiencies
  • Continued extraordinarily high R&D spend during 2021-22, after which, the spend relative to revenue will decrease in parallel with the completion of large-scale development work on the respiratory tablet portfolio
  • Further leveraging of ALK’s existing sales and marketing platforms meaning that sales and marketing costs relative to revenue will further decrease
  • Annual CAPEX of around DKK 300 million associated with strategic investments, maintenance, optimisation efforts and IT
  • No revenue from acquisitions, new partnerships or the in-licensing of adjacent products and services has been included, nor have any sizeable payments related to M&As or in-licensing activities
Corporate matters Sustainability Governance and ownership Risk management Remuneration Board of Directors Board of Management
34 37 40 43 44 46

Sustainability

In 2020, ALK instigated a step change in its commitment to sustainability with a continuing focus on ensuring good health and well-being for all, the details of which were formalised in a strategy titled ‘Access to Allergy Care for All’.

Materiality assessment chart

Monitoring development and impact
Continuous and systematic approach
Increase strategic efforts to optimise positive impact

ALK’s sustainability activities aim to mitigate risks and adverse impacts related to its business activities while also contributing to solving societal and environmental challenges where possible. To support its sustainability strategy further, ALK conducted a materiality assessment in 2020 to identify those aspects with the highest impact on its business and stakeholders. The assessment was based on a business analysis as well as input from relevant internal and external stakeholders, and it now forms the basis for target-setting and the prioritisation of resources.

ALK business impact

Access to medicines

These include policies on sustainability, environment, health and safety (EHS), tax, diversity, investor relations, remuneration, as well as anti-corruption and bribery policies.

Performance highlights 2020

The materiality assessment identified access to medicines, and helping as many people with allergy as possible, as key priorities for ALK’s sustainability activities. Over the years, ALK’s solutions have helped many people around the world. However, many more still lack access to modern medical care for their allergies and related asthma.

38% of all consumed energy came from
renewable energy sources
CO2 emissions were reduced by 32% compared to a 2017-baseline
Women made up 46% of all managers
94% of employees were trained in business ethics compliance

ALK aims to improve this by partnering with healthcare systems and professionals around the world, and through the wider democratisation and dissemination of its allergy solutions. This ambition covers the full range of ALK’s research, its diagnosis, treatment, disease modification and prevention solutions, as well as its training, education and awareness-raising expertise. The ultimate goal is an introduction of allergy solutions earlier in the patient journey in order to achieve better treatment outcomes for ever more people, wherever they may be.

In addition, ALK’s Code of Conduct outlines the company’s expectations when it comes to professionalism, honesty and integrity. Every ALK manager is tasked with ensuring that each employee is familiar with the code and its importance. Furthermore, all employees are required to read and sign off on their commitment to it every year, and to complete an online training programme covering various aspects of the code.

Policies and guidelines

ALK has various policies and guidelines in place to ensure its everyday activities support the commitments it has made. At the same time, ALK remains committed to the UN Global Compact Principles and contributes to addressing 11 of the UN Sustainable Development Goals. ALK’s statutory annual report on sustainability and the gender diversity of management (as required by §99a, §99b and §107d of the Danish Financial Statements Act) is available at www.alk.net/ sustainability. This report also highlights important actions taken in 2020 to support the UN Sustainable Development Goals.

ESG key figures overview

Unit 2020 2019 2018 2017 2016
Environmental data
CO2e scope 1 Tonnes 3,232 3,380 3,134 6,443
CO2e scope 2 Tonnes 6,239 4,419 5,238 3,729
Energy consumption GJ 163,580 169,398* 168,035 169,275
Renewable energy share % 38 20 13 13
Water consumption 110,530 122,461 117,252 120,960
Social data
Workforce Headcount 2,486 2,406 2,369 2,284
Gender diversity, percentage of women % 63 62 62 62
Gender diversity, percentage of women at all management levels % 46 47 46 47
Gender pay ratio of men to women Times 1.14 1.13 1.12 1.16
Employee turnover ratio, voluntary and involuntary % 10 11 11 12
Absence due to sickness % 3.1 2.7 n/a n/a
Governance data
Gender diversity, women as a percentage of shareholder-elected Board % 20 17 20 17
Board meeting attendance rate % 98 97 98 96
CEO pay ratio Times 34 33 49 n/a**

* A reporting discrepancy was found post-publication of the 2020 annual report. The figure is updated to 169,398 from 164,639 reported last year
** In 2016, ALK did not have a CEO for the full year

Environment
CO2 Scope 1 + 2 emissions include all material types of fuels and refrigerants, including HFCs, gas oil, diesel, heating etc. Renewable energy is subtracted from reported total CO2-emissions. Energy consumption in GJ is calculated as MWh*3.6. All environmental data is reported for production sites only (Hørsholm, Madrid, Vandeuil, Varennes, Port Washington, Post Falls and Oklahoma)

Social
Workforce is calculated as the headcount of permanent + temporary employees on 31 December 2020. All data is downloaded from ALK's internal HR system Workday. The gender pay ratio is calculated by comparing the median total compensation of men to women. The CEO is excluded. The turnover ratio is calculated by dividing the number of employees who left the company by the average number of employees in the reporting year. Absence is calculated as number of working days with absence due to sickness, divided by total working days

Governance
The CEO pay ratio is calculated as total compensation divided by median staff total compensation. The board meeting attendance rate is calculated as (number of meetingsnumber of members)-meetings not attended/(number of meetingsnumber of members)*100

Governance and ownership

ALK share price up 53%
Corporate governance statement furthermore describes key elements of ALK’s internal controls and risk management systems relating to financial reporting processes.# ALK’s statutory corporate governance statement for the financial year 2020

The full Board of Directors’ ‘comply or explain’ review is available at https://ir.alk.net/corporate-governance. ALK’s statutory corporate governance statement for the financial year 2020, pursuant to section 107b of the Danish Financial Statement Act, is available at https://ir.alk.net/financial-reporting/risk-management.

since 1 January 2020

At the annual general meeting in March 2020, Anders Hedegaard was elected as the new Chairman of the Board of Directors and Lene Skole was re-elected as Vice Chairman. Lars Holmqvist, Jakob Riis and Vincent Warnery were all re-elected as members of the Board of Directors.

As a listed company, ALK is subject to the recommendations of the Danish Committee on Corporate Governance. ALK fulfils this obligation either by complying with its recommendations or by explaining the reason for non-compliance. ALK complies with 45 of the 47 recommendations. The exceptions in 2020 being that there was an overweight of non-independent directors on the Board (three out of five) and that the majority of members of the Audit Committee and Remuneration Committee were non-independent.

Major shareholder

The statement provides a detailed account of ALK’s management structure, including the Board of Directors’ composition, activities, remuneration and self-assessment.

The Lundbeck Foundation owns 40.3% of ALK’s shares. As announced on 6 November 2020, the Board of Directors will propose the election of Gitte Pugholm Aabo, CEO of GN Hearing A/S and Bertil Lindmark, Chief Medical Officer of Galecto A/S as new, independent members of the Board at the Company’s annual general meeting on 18 March 2021.

The Board has proposed establishing an adequate balance between independent and non-independent directors in 2021 by nominating two new, independent members to the Board of Directors, thus increasing the number of shareholder-elected members to seven. If the nominations are approved at the annual general meeting on 18 March 2021, the majority of the shareholder-elected members will be independent.

ALK’s statutory corporate governance statement for the financial year 2020, pursuant to section 107b of the Danish Financial Statement Act Available at: https://ir.alk.net/financial-reporting/risk-management

The Board of Directors’ ‘comply or explain’ review Available at: https://ir.alk.net/corporate-governance

For the Audit and Remuneration Committees, ALK took an approach of selecting the best possible options in terms of experience and capabilities.

Core data for the share

Share capital Nominal value Number of A shares Number of AA shares Number of B shares Stock exchange Ticker symbol Indices ISIN Bloomberg code Reuters code ADR ticker symbol LEI code
DKK 111,411,960 DKK 10 per share 920,760 units with 10 votes per share 92,076 units with 10 votes per share 10,128,360 units with 1 vote per share Nasdaq Copenhagen ALK B X4500 (healthcare), OMXCLCPI (LargeCap) and OMXCPI (all) DK0060027142 ALKB_CO AKABY 529900SGCREUZCZ7P020

Management’s review • Annual report 2020 • ALK 38

Shareholder information

(98%). As at 31 December 2020, two shareholders had notified shareholdings of 5% or more: the Lundbeck Foundation had a 40.3% interest (including A shares and AA shares) and ATP had a 7.5% interest. Of the 30 largest registered shareholders, the vast majority were institutional investors – from North America, the UK and Scandinavia in particular. In the shareholder register, the international ownership was estimated at approximately 23% (23%), representing 36% of the free float of the B share capital (36%), excluding the Lundbeck Foundation’s holding and treasury shares.

Major shareholders* and treasury shares as at 31 December 2020

Shareholder Registered office Number of shares Interest Votes
The Lundbeck Foundation Copenhagen, Denmark 920,720 A shares 92,072 AA shares 3,474,827 B shares 40.3% 67.2%
ATP** Hillerød, Denmark 830,794 B shares 7.5% 1.9%
ALK – own shares Hørsholm, Denmark 212,873 B shares 4.1% -
  • Notified shareholdings of 5% or more of the company’s shares
    ** The Danish Labour Market Supplementary Pension

The aim is that the share price should offer a fair representation of ALK and reflect the company’s actual and expected ability to create shareholder value. ALK would further like the share to be liquid and to have a sound foundation, allowing for fair pricing and trading in the share.

Ownership

The total share capital is divided into A shares, AA shares and B shares (cf. core data table on the previous page). The A shares and AA shares are not listed and are predominantly held by the Lundbeck Foundation, while all B shares are listed and freely negotiable. At the end of 2020, ALK had 17,697 registered shareholders, versus 12,979 at the end of 2019. The registered shareholders owned 98% of the share obligations related to ALK’s long-term incentive programmes.

2020 at DKK 2,500. The daily trading liquidity improved further during 2020 and averaged DKK 31 million (20). ALK’s holding of its own shares was reduced following the settlement of share option and conditional share programmes. At the end of the year, ALK held 212,873 or 1.9% of its own shares (2.2% at the end of 2019) which is considered sufficient to cover current

Return and liquidity

ALK aims to provide long-term shareholder return through an increased share price, the paying-out of dividends, and the purchase of its own shares. At the end of 2019, the share price was DKK 1,635 and the share closed

Dividend and capital structure

The Board of Directors considers that ALK’s financial resources, including credit facilities, still constitute a sufficient financial basis for implementing the next stage of ALK’s strategy. In support of the strategy, the Board of Directors is extending its recommendation that dividend payments be temporarily suspended until business profitability improves further. In line with this decision, at the annual general meeting in March 2021, the Board of Directors will propose that no dividend be declared.

The Board of Directors will revisit the dividend policy and ALK’s capital structure on an ongoing basis during the next phase of the strategy.

The ALK share in 2020

Index 160 140 120 100 80
ALK OMXC20 CAP (indexed)
Pharma, biotech and life sciences (NBI-NAS, indexed)
40.3%
50.3%
7.5%
1.9%
60
Jan Feb Mar Apr May
2020

Management’s review • Annual report 2020 • ALK 39

Investor relations

Financial calendar 2021

Based on its investor relations (IR) policy (https://ir.alk.net/corporate-governance/ ir-policy), ALK seeks to provide timely, accurate and relevant information on matters of importance to the assessment of the share, including strategy, operations, performance, expectations, goals, pipeline, market development, and other matters. ALK continuously works to strengthen its dialogue with all financial stakeholders in accordance with good IR practice and the provisions for companies listed on Nasdaq Copenhagen.

  • Annual general meeting: 18 March
  • Three-month interim report (Q1): 5 May
  • Six-month interim report (Q2): 11 August
  • Nine-month interim report (Q3): 11 November

Find out more

Visit Investor Relations at https://ir.alk.net/investors

Besides hosting regular telephone conferences, ALK representatives held a large number of individual meetings and briefing calls with analysts and investors in 2020 and also presented at various investor conferences.

Contact Investor Relations:
Per Plotnikof
Tel. +45 4574 7527

The Lundbeck Foundation

As one of the largest commercial foundations in Denmark, the Lundbeck Foundation lives its purpose every day through engaged ownership of its three subsidiaries and an annual spend of at least DKK 500 million in grants to support biomedical research with a special focus on neuroscience. Founded in 1954 by the widow of the founder of the Danish pharmaceutical company, H. Lundbeck A/S, the Foundation is the largest and controlling shareholder of ALK, owning 67% of the votes (40% of the capital). In addition, the Foundation is the majority shareholder of two other large Danish companies, Lundbeck and Falck, and manages securities of about DKK 19 billion. The Lundbeck Foundation also invests in European and American life-science companies and supports a range of early-stage investment projects based on Danish research. Every year, the Foundation awards The Brain Prize, a personal research prize of DKK 10 million. The prize is awarded to one or more scientists who have distinguished themselves through an outstanding contribution to global neuroscience and who are still active in research. For further information on the Foundation, please visit www.lundbeckfonden.com.

During the year, ALK published 13 company announcements (22), including reports on transactions by managerial staff. All announcements are available on ALK’s website together with reports, presentations, access to telephone conferences, share price information, estimates from analysts following the share, and related information. Registered shareholders are encouraged to sign up at the InvestorPortal.

The Lundbeck Foundation’s business activities encompass three large subsidiaries, an international portfolio of 17 venture companies, a portfolio of seven biotech start-ups based on research from Danish universities, and internal management of securities of around DKK 19 billion. www.lundbeckfonden.com

Management’s review • Annual report 2020 • ALK 40

Risk management

Production and sub-supplier issues impacting product supply

Quality issues impacting patient safety and product supply

ALK’s Board of Management is responsible for the ongoing management of risks throughout the value chain, including risk mapping, the assessment of probabilities and potential consequences, and the Description Description

ALK has concentrated its key in-house production capacity at plants in Denmark, France, Spain and the USA.# Management's review

Annual report 2020 • ALK 41

Although the plants are located in areas that have not historically been hit by natural disasters, this geographical spread calls for risk planning in order to avoid emergencies, such as lack of, or poor access to raw materials: for instance, pollen. ALK’s products are subject to a large number of statutory and regulatory requirements with respect to issues such as safety, efficacy and production. Meeting high product quality standards is a prerequisite for the company’s ability to supply products and hence its competitive strength. Introduction of risk-reducing measures. As ALK works to rationalise its portfolio, there may be risks associated with the discontinuation of its products. Among others, these may include potential disruption at manufacturing sites during decommissioning work, the loss of sales from products for which no suitable ALK substitute product exists, or the inability to meet sudden spikes in demand for other products due to patients switching from discontinued products. ALK’s products may be associated with allergic reactions of varying extents, durations and severities. If such events occur in unexpected situations, they may have an impact on the company’s earnings and sales.

The Board of Management has established a risk committee to assist it in meeting its overall responsibility for risk management. The Risk Committee comprises dependency on third parties for supplying input for key production processes and commercialising the company’s products in several markets entails risks that ALK would not be subject to if the company possessed the necessary in-house capabilities. representatives from each functional area relevant to ALK’s risk profile. It meets twice a year or more, as required, to perform its tasks. Risks are systematically assessed according to a two-dimensional matrix, rating the impact and probability of each risk. A risk management report with key risks and recommended mitigation plans is presented to Board of Management before it is submitted to the Board of Directors on an annual basis for their review and approval.

Risk mitigation

ALK conducts risk planning including for the prevention of unwanted events, and preventative inventory management, such as the build- up of contingency stocks in order to ensure an unbroken chain of production and supply. Production and manufacturing processes are subject to periodic and routine inspections by regulatory authorities as a regular part of their monitoring processes to ensure that ALK observes the prescribed requirements and standards. ALK’s production processes and quality standards have been developed and optimised over many years. ALK has invested significantly to increase the robustness and compliance of the legacy business by reducing manufacturing complexity, and all possible steps are taken during portfolio rationalisation work to mitigate any potential impact on other areas of manufacturing or the wider business. ALK stringently monitors product quality and safety, both in clinical development and in sales and marketing activities. If, despite the high levels of quality and safety, a situation should occur in which it is necessary to recall a product, ALK has procedures in place to ensure that this can be managed swiftly and effectively and in accordance with regulatory requirements. ALK manages third party dependency risks through contractual stipulations, planning, monitoring, and joint steering committees.

Failures or delays in product development

Description: The future success of ALK depends on the company’s ability to maintain current products and to successfully identify, develop and market new, innovative drugs, which involves significant risks. A pharmaceutical drug must be subjected to extensive and lengthy clinical trials to document qualities such as safety and efficacy before it can be approved for marketing. During the development process, the outcomes of these trials are subject to significant risks. Even though substantial resources are invested in the development process, the trials may produce negative results. Failures or delays in the development process or in obtaining regulatory approvals may have a major impact for the patients not being able to benefit from the products and on the ability of ALK to achieve its long-term goals.

Risk mitigation: ALK and its collaborative partners perform thorough risk assessments of their research and development programmes throughout the development and registration processes with the objective of risk mitigation to optimise the likelihood of the products reaching the market.

Tablets not gaining market acceptance

Description: If ALK and its partners succeed in developing new products and obtaining regulatory approvals for them, the ability to generate revenue depends on the products being accepted by doctors and patients. The degree of market acceptance for a new product or drug candidate depends on several factors, including the demonstration of clinical efficacy and safety, cost-effectiveness, convenience and ease of administration, potential advantages over alternative treatment methods, competition, and marketing and distribution support. If ALK’s new products, primarily tablets, fail to achieve market acceptance, this could have a significant influence on the company’s ability to generate revenue. Even if market acceptance of the tablets is successfully achieved, the extent of their acceptance could influence the company’s ability to fully deliver on its sales -growth targets for these products.

Risk mitigation: ALK regularly conducts extensive surveys of market conditions and similar factors and commits significant resources to providing information on its products to doctors and patients. ALK’s Scientific Committee is responsible for other patient-/product-related innovation activities. The committee advises on matters relating to R&D activities and other patient-/product-related innovation activities, including reviewing R&D programmes and the overall R&D pipeline.

Authorities introducing new pricing pressures

Description: In most of the countries in which ALK operates, prescription drugs are subject to reimbursement from, and price controls by, national authorities and healthcare providers. This often results in significant price differences between individual markets. Regulatory requirements and interventions, as well as price control measures, may therefore have a significant impact on the company’s earnings capacity. Exceptionally, governments and national authorities may introduce economic measures that also affect the pricing and reimbursement of medicines, for example, as a consequence of the impact of COVID on healthcare budgets or as a result of a major economic downturn. Equally, there may be circumstances that prevent planned price increases, with a consequent impact on revenue.

Risk mitigation: ALK is strongly committed to evidenced-based medicine, based on strong clinical and health economic evidence as the basis for pricing and reimbursement. ALK actively engages in dialogue with authorities with the aim of securing fair pricing and reimbursement agreements and maintains a strong focus on its market access strategy.

Competition becoming more intense

Description: ALK operates in competitive markets. If, for instance, a competitor were to launch a new and more effective treatment for allergy, it may have a material impact on ALK’s sales. A competitive market may also lead to market-driven price reductions just as national and regional authorities may mandate price reductions. Both competition and pricing risks may have a material impact on ALK’s ability to achieve its long-term goals.

Risk mitigation: ALK’s Scientific Committee monitors the competitor landscape in global AIT research and development to ensure a timely response to developments by competitors or in the market. As a consequence, and to stay ahead of competition, ALK monitors economic, market and regulatory developments as they relate to product pricing, along with the competitive situation and initiatives in all important markets with the aim of appropriate risk mitigation. Sales growth targets are set with a full understanding of the potential risks involved in successfully marketing any product and these are anticipated and managed so far as is possible.

IT security breaches impacting business continuity

Description: Disruption to IT systems, such as breaches of data security, may occur across the global value chain, where well-functioning IT systems and infrastructure are critical for the company’s ability to operate effectively.

Risk mitigation: ALK manages this risk, among other ways, by having a security strategy in place to prevent intruders from causing damage to systems or gaining access to critical data and systems. Awareness campaigns, access controls, intrusion detection and prevention systems have all been implemented, and systems are regularly upgraded to increase network security.

Breaches of legal or ethical standards

Description: Non-compliance with applicable regulations, legislation, or ALK’s Code of Conduct could negatively affect the company’s good reputation which is essential for operating within the pharmaceutical industry.

Risk mitigation: ALK strives to act professionally, honestly, and with high integrity throughout the company in relation to stakeholders.

Fluctuations in exchange rates and interest rates

Description: Due to the nature of its operations, investments and financing, ALK is exposed to fluctuations in exchange rates and interest rates, which could impact the company’s cash flow and earnings. Patents and other intellectual property rights are important for developing and retaining ALK’s competitive strength.

Risk mitigation:

Management's Review

ALK’s Code of Conduct defines ALK’s high standard of ethical behaviour in relation to customers, employees, shareholders, society, suppliers and partners. Immediate action is taken on substantiated non-compliance. Annually, all employees are asked to sign and confirm their knowledge of the Code of Conduct and to take an online test.

The company’s financial risks are managed centrally, based on policies approved by the Board of Directors. The objective of ALK’s financial risk management is to reduce the sensitivity of earnings to fluctuations in exchange rates, interest rates, liquidity and changes in credit rating. Company policy is to refrain from active financial speculation. See note 25 of this annual report for a specification of the company’s exposure to currency, interest rate and credit risks and its use of derivative financial instruments.

Internal controls and policies are in place to safeguard ALK’s intellectual property rights. The risk that ALK might infringe patents or trademark rights held by other companies, as well as the risk that other companies may attempt to infringe the patents and/or trademark rights of ALK are monitored and, if necessary, suitable measures are taken.

Remuneration

ALK’s remuneration policy was prepared in accordance with the Danish Companies Act and approved by shareholders at the annual general meeting in 2020. The remuneration policy replaced the previous remuneration guidelines and guidelines for incentive pay, and governs the remuneration for the Board of Directors and Board of Management.

The overall aim of the remuneration policy is to outline the overall framework for remuneration at ALK and to provide shareholders with a clear, understandable and comprehensive overview of the remuneration provided by ALK. The objectives of the remuneration policy are to:

  • Attract, motivate and retain qualified members of the Board of Directors and Board of Management
  • Align the remuneration components to the interests of shareholders
  • Contribute to promoting value creation at ALK and to support ALK’s business strategy
  • Ensure that the remuneration of individual members of Board of Management reflect the company's performance as well as individual results

In 2020, the remuneration for the Board of Directors and Board of Management followed the structure and principles outlined in the remuneration policy.

Remuneration Report

ALK has prepared a separate report that describes remuneration for the Board of Directors and Board of Management in more detail. The remuneration report provides an overview of the components in the remuneration for the Board of Directors and Board of Management, including an overview of the actual remuneration in 2020, the development in remuneration for the past three years, as well as the shareholdings of the Board of Directors and Board of Management. The remuneration report is available at https://ir.alk.net/corporate-governance.

Board of Directors and Board of Management

Board of Directors

Name Role Board Member Since Committee Competences Directorships
Anders Hedegaard Chairman 2013** Chairman of the Audit Committee Chairman of the Nomination Committee Specific expertise within management and sales & marketing in international life science and consumer care companies. Rodenstock Group, CEO
Lene Skole* Vice Chairman 2020** Chairman of the Remuneration Committee Member of the Audit Committee Experience in management, financial and economic expertise, experience in strategy and communication in international companies. The Lundbeck Foundation, CEO, and directorships at two subsidiaries Orphazyme A/S Falck A/S, Vice Chairman H. Lundbeck A/S, Vice Chairman Tryg Forsikring A/S Tryg A/S Biovica International AB, Chairman H. Lundbeck A/S The Lundbeck Foundation Tecan AG, Switzerland Naga UK Topco Limited, UK Vitrolife AB, Sweden Danish Business Promotion Board, Chairman Ørsted A/S, Vice Chairman
Lars Holmqvist* Board member 2015** Member of the Nomination Committee Member of the Remuneration Committee Member of the Scientific Committee Experience in management, finance, and sales & marketing in international life science companies, including med-tech and pharmaceutical companies. Professional board member
Jakob Riis* Board member 2014** Member of the Audit Committee Member of the Scientific Committee Experience in management and sales & marketing in the international healthcare industry. Falck A/S, President & CEO
Vincent Warnery Board member 2019** Experience in management and sales & marketing in the international consumer healthcare industry. Beiersdorf AG, Executive Board Member
Katja Barnkob Employee-elected, Board member 2011 Experience in project management of global drug development projects in the pharmaceutical industry.
Nanna Rassov Carlson Employee-elected, Board member 2019 Expertise in production and release of ALK’s active pharmaceutical ingredients for SLIT products.
Johan Smedsrud Employee-elected, Board member 2019 Experience in HVAC systems, cleanroom testing, utensil washing and sterilisation for the pharmaceutical industry.

* These board members are not regarded as independent in the sense of the definition contained in the Danish recommendations on corporate governance due to being affiliated with the Lundbeck Foundation, which owns 40.3% of ALK’s shares.
** All members elected at the annual general meeting are subject to re-election each year.

Board Meeting Attendance

Committee Anders Hedegaard2 Lene Skole Lars Holmqvist Jakob Riis Vincent Warnery Katja Barnkob4 Nanna Rassov Carlson4 Johan Smedsrud4
Board meetings All meetings All meetings All meetings All meetings All meetings All meetings All meetings All meetings
Audit Committee All meetings All meetings All meetings
Remuneration All meetings All meetings
Scientific Committee All meetings All meetings
Nomination Committee1 All meetings All meetings

1 The Nomination Committee meets when required.
2 elected at the AGM on 11 March 2020.
3 stepped down at the AGM on 11 March 2020.
4 employee-elected.

Board of Management

Name Role Competences Directorships
Carsten Hellmann President & CEO Executive management experience in global healthcare and biopharmaceutical companies. Coloplast A/S Dansk Erhverv
Henrik Jacobi Executive Vice President, Research & Development Experience in management, innovation, and research & development in the pharmaceutical industry. Henrik Jacobi holds a degree in Medicine from 1993.
Søren Jelert Executive Vice President & CFO Experience in management, and financial and economic expertise in the pharmaceutical industry and other sectors.
Søren Niegel Executive Vice President, Commercial Operations Experience in management as well as global production and sales & marketing within the pharmaceutical industry.

Consolidated Financial Statements

Statements

  • Statement by Management on the annual report
  • Independent auditor’s reports
  • Consolidated financial statements
    • Income statement
    • Statement of comprehensive income
    • Cash flow statement
    • Balance sheet
    • Statement of changes in equity
    • Notes
  • Parent company financial statements
    • Income statement
    • Balance sheet
    • Statement of changes in equity
    • Notes

Statement by Management on the annual report

The Board of Directors and the Board of Management have today considered and adopted the annual report of ALK-Abelló A/S for the financial year 1 January to 31 December 2020.

The consolidated financial statements have been prepared in accordance with International Financial Reporting Standards as adopted by the EU and further requirements in the Danish Financial Statements Act. The parent company financial statements have been prepared in accordance with the Danish Financial Statements Act. Management's review has been prepared in accordance with the Danish Financial Statements Act.

In our opinion, the consolidated financial statements and the parent company financial statements give a true and fair view of the financial position at 31 December 2020 of the group and the parent company and of the results of the group and parent company operations and consolidated cash flows for the financial year 1 January to 31 December 2020.

In our opinion, Management's review includes a true and fair account of the development in the operations and financial circumstances of the group and the parent company, of the results for the year and of the financial position of the group and the parent company as well as a description of the most significant risks and elements of uncertainty facing the group and the parent company.

Board of Management
Carsten Hellmann
President & CEO

Henrik Jacobi
Executive Vice President, Research & Development

Søren Jelert
Executive Vice President & CFO

Søren Daniel Niegel
Executive Vice President, Commercial Operations

Board of Directors
Anders Hedegaard
Chairman

Lene Skole
Vice Chairman

Katja Barnkob
Jakob Riis# Independent Auditor's Report

Nanna Rassov Carlson
Johan Smedsrud
Lars Holmqvist
Vincent Warnery

In our opinion, the annual report of ALK-Abelló A/S for the financial year 1 January to 31 December 2020 identified as "ALK-2020-12-31.zip" is prepared, in all material respects, in compliance with the ESEF Regulation.

We recommend that the annual report be adopted at the annual general meeting.

Hørsholm, 10 February 2021

Statements • Annual report 2020 • ALK 49

Independent auditor’s reports

To the shareholders of ALK-Abelló A/S

What we have audited

The Consolidated Financial Statements and the Parent Company Financial Statements of ALK-Abelló A/S for the financial year 1 January to 31 December 2020 which comprise income statement, balance sheet, statement of changes in equity and notes, including summary of significant accounting policies for the Group as well as for the Parent Company and statement of comprehensive income and cash flow statement for the Group. Collectively referred to as the “Financial Statements”.

Independence

We are independent of the Group in accordance with the International Ethics Standards Board for Accountants’ Code of Ethics for Professional Accountants (IESBA Code) and the additional requirements applicable in Denmark. We have also fulfilled our other ethical responsibilities in accordance with the IESBA Code. To the best of our knowledge and belief, prohibited non-audit services referred to in Article 5(1) of Regulation (EU) No 537/2014 were not provided.

Report on the audit of the Financial Statements

Our opinion

In our opinion, the Consolidated Financial Statements give a true and fair view of the Group’s financial position at 31 December 2020 and of the results of the Group’s operations and cash flows for the financial year 1 January to 31 December 2020 in accordance with International Financial Reporting Standards as adopted by the EU and further requirements in the Danish Financial Statements Act.

Moreover, in our opinion, the Parent Company Financial Statements give a true and fair view of the Parent Company’s financial position at 31 December 2020 and of the results of the Parent Company’s operations for the financial year 1 January to 31 December 2020 in accordance with the Danish Financial Statements Act.

Basis for opinion

We were appointed auditors of ALK-Abelló A/S for the first time on 11 March 2020 for the financial year 2020. We conducted our audit in accordance with International Standards on Auditing (ISAs) and the additional requirements applicable in Denmark. Our responsibilities under those standards and requirements are further described in the Auditor’s responsibilities for the audit of the Financial Statements section of our report. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion. Our opinion is consistent with our Auditor’s Long-form Report to the Audit Committee and the Board of Directors.

Key audit matters

Key audit matters are those matters that, in our professional judgement, were of most significance in our audit of the Financial Statements for 2020. These matters were addressed in the context of our audit of the Financial Statements as a whole, and in forming our opinion thereon, and we do not provide a separate opinion on these matters.

Key audit matter How our audit addressed the key audit matter
The valuation of inventories, which includes raw materials, work in progress and manufactured goods and goods for resale. We evaluated and discussed inventory accounting policy with Management. We evaluated related application and monitoring controls. We selected a sample and tested the costing model for allocation of indirect production costs and analysed the allocation of indirect production costs between the Group’s products. We selected a sample and tested product cost prices, including tests of raw material prices and allocated indirect production costs. We assessed and challenged Management’s assumptions and judgements related to the allocation of indirect production costs, including capacity utilisation, and the assumptions used in eliminating unrealised internal profit. Furthermore, we tested the Group’s model for eliminating unrealised internal profit in the Consolidated Financial Statements. We assessed the appropriateness of the related disclosure provided in the Consolidated Financial Statements. We refer to notes 2 and 15 in the Consolidated Financial Statements.
The valuation is based on a costing model, which includes a number of significant accounting judgements and estimates related to allocation of indirect production costs, including capacity utilisation, and the model for eliminating unrealised internal profit in the Consolidated Financial Statements. We focused on this area as the amounts involved are material and as the valuation is associated with significant accounting estimates and judgements. This includes the complex models for indirect production costs and eliminating unrealised internal profits and the assumptions used for measuring indirect production costs and unrealised internal profits.
Valuation of deferred tax assets We assessed the method applied by Management for calculating the deferred tax assets and assessing its valuation. We tested the calculation of the deferred tax assets prepared by Management and involved our internal tax specialist in assessing the tax calculation to ensure compliance with relevant tax legislation. We focused on this area as the amounts involved are material and as the valuation of deferred tax assets is associated with significant accounting estimates and judgements. This includes the estimation uncertainty regarding assessing the future taxable profits in ALK- Abelló A/S and within the Danish joint taxation group. We evaluated and challenged the documentation prepared by Management regarding the deferred tax asset, including Management’s best estimate of the probability of realising the future taxable profits in Denmark and within the joint Danish taxation group, including sensitivity and risk analysis. We assessed the appropriateness of the related disclosure provided in the Consolidated Financial Statements. We refer to notes 2, 9 and 14 in the Consolidated Financial Statements.
Utilisation of the recognised deferred tax assets is depending on the expected future taxable income within the Danish joint taxation group with the Lundbeck Foundation and its other subsidiaries.

Statements • Annual report 2020 • ALK 50

Statement on Management’s Review

Our opinion on the Financial Statements does not cover Management’s Review, and we do not express any form of assurance conclusion thereon. In connection with our audit of the Financial Statements, our responsibility is to read Management’s Review and, in doing so, consider whether Management’s Review is materially inconsistent with the Financial Statements or our knowledge obtained in the audit, or otherwise appears to be materially misstated. Moreover, we considered whether Management’s Review includes the disclosures required by the Danish Financial Statements Act. Based on the work we have performed, in our view, Management’s Review is in accordance with the Consolidated Financial Statements and the Parent Company Financial Statements and has been prepared in accordance with the requirements of the Danish Financial Statements Act. We did not identify any material misstatement in Management’s Review.

Management’s responsibilities for the Financial Statements

Management is responsible for the preparation of consolidated financial statements that give a true and fair view in accordance with International Financial Reporting Standards as adopted by the EU and further requirements in the Danish Financial Statements Act and for the preparation of parent company financial statements that give a true and fair view in accordance with the Danish Financial Statements Act, and for such internal control as Management determines is necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error.

In making the financial statements, Management is responsible for assessing the Group’s and the Parent Company’s ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless Management either intends to liquidate the Group or the Parent Company or to cease operations, or has no realistic alternative but to do so.

The Audit Committee and the Board of Directors are responsible for overseeing the Group’s financial reporting process.

Auditor’s responsibilities for the audit of the Financial Statements

Our objectives are to obtain reasonable assurance about whether the Financial Statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an auditor’s report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a guarantee that an audit conducted in accordance with ISAs and the additional requirements applicable in Denmark will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of these Financial Statements.

As part of an audit in accordance with ISAs and the additional requirements applicable in Denmark, we exercise professional judgement and maintain professional scepticism throughout the audit. We also:

  • Identify and assess the risks of material misstatement of the Financial Statements, whether due to fraud or error, and design and perform audit procedures responsive to those risks. Such procedures include examining, on a test basis, evidence regarding the amounts and disclosures in the Financial Statements. We also evaluate the overall presentation, structure and content of the Financial Statements, including the disclosures, and whether the Financial Statements represent the underlying transactions and events in a manner that achieves fair presentation.

  • Obtain an understanding of internal control relevant to the audit in order to design audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Group’s internal control.

  • Evaluate the appropriateness of accounting policies used and the reasonableness of accounting estimates and related disclosures made by Management.

  • Conclude on the appropriateness of Management’s use of the going concern basis of accounting and based on the audit evidence obtained, whether a material uncertainty exists related to events or conditions that may cast significant doubt on the Group’s and the Parent Company’s ability to continue as a going concern. If we conclude that a material uncertainty exists, we are required to draw attention in our auditor’s report to the related disclosures in the Financial Statements or, if such disclosures are inadequate, to modify our opinion. Our conclusions are based on the audit evidence obtained up to the date of our auditor’s report. However, future events or conditions may cause the Group or the Parent Company to cease to continue as a going concern.

  • Evaluate the overall presentation, structure and content of the Financial Statements, including the disclosures, and whether the Financial Statements represent the underlying transactions and events in a manner that achieves fair presentation.

We communicate with those charged with governance regarding, among other things, the planned scope and timing of the audit and significant audit findings, including any significant deficiencies in internal control that we identify during our audit.

We are required to obtain representation from those charged with governance and Management acknowledging their responsibilities for fair presentation of the Financial Statements and their assertion that they have provided us with all relevant information and that all transactions have been recorded in the accounting records and are reflected in the Financial Statements.

We are responsible for the direction, supervision and performance of the group audit. We remain solely responsible for our audit opinion.

Statements • Annual report 2020 • ALK 51## Auditor's Responsibilities for the Audit of the Financial Statements

Our objectives are to obtain reasonable assurance about whether the Financial Statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an auditor’s report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a guarantee that an audit conducted in accordance with ISAs and the additional requirements applicable in Denmark will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of the Financial Statements.

As part of an audit in accordance with ISAs and the additional requirements applicable in Denmark, we exercise professional judgement and maintain professional scepticism throughout the audit. We also:

  • Obtain an understanding of internal control relevant to the audit in order to design audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Group’s and the Parent Company’s internal control.
  • Identify and assess the risks of material misstatement of the Financial Statements, whether due to fraud or error, design and perform audit procedures responsive to those risks, and obtain audit evidence that is sufficient and appropriate to provide a basis for our opinion. The risk of not detecting a material misstatement resulting from fraud is higher than for one resulting from error, as fraud may involve collusion, forgery, intentional omissions, misrepresentations, or the override of internal control.
  • Obtain sufficient appropriate audit evidence regarding the financial information of the entities or business activities within the Group to express an opinion on the Financial Statements.
  • Evaluate the overall presentation, structure and content of the Financial Statements, including the disclosures, and whether the Financial Statements represent the underlying transactions and events in a manner that achieves fair presentation.

In preparing the Financial Statements, Management is responsible for assessing the Group’s and the Parent Company’s ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless Management either intends to liquidate the Group or the Parent Company or to cease operations, or has no realistic alternative but to do so.

From the matters communicated with those charged with governance, we determine those matters that were of most significance in the audit of the Financial Statements of the current period and are therefore the key audit matters. We describe these matters in our auditor’s report unless law or regulation precludes public disclosure about the matter or when, in extremely rare circumstances, we determine that a matter should not be communicated in our report because the adverse consequences of doing so would reasonably be expected to outweigh the public interest benefits of such communication.

We communicate with those charged with governance regarding, among other matters, the planned scope and timing of the audit and significant audit findings, including any significant deficiencies in internal control that we identify during our audit. We also provide those charged with governance with a statement that we have complied with relevant ethical requirements regarding independence, and to communicate with them all relationships and other matters that may reasonably be thought to bear on our independence, and where applicable, related safeguards.

Report on compliance with the ESEF Regulation

Consolidated financial statementsAnnual report 2020ALK 52

As part of our audit of the Financial Statements we performed procedures to express an opinion on whether the annual report of ALK-Abelló A/S for the financial year 1 January to 31 December 2020 with the filename ALK-2020-12-31.zip is prepared, in all material respects, in compliance with the Commission Delegated Regulation (EU) 2019/815 on the European Single Electronic Format (ESEF Regulation) which includes requirements related to the preparation of the annual report in XHTML format and iXBRL tagging of the Consolidated Financial Statements.

Our responsibility is to obtain reasonable assurance on whether the annual report is prepared, in all material respects, in compliance with the ESEF Regulation based on the evidence we have obtained, and to issue a report that includes our opinion. The nature, timing and extent of procedures selected depend on the auditor’s judgement, including the assessment of the risks of material departures from the requirements set out in the ESEF Regulation, whether due to fraud or error.

The procedures include:

  • Testing whether the annual report is prepared in XHTML format;
  • Obtaining an understanding of the company’s iXBRL tagging process and of internal control over the tagging process;
  • Evaluating the completeness of the iXBRL tagging of the Consolidated Financial Statements;
  • Ensuring consistency between iXBRL tagged data and the Consolidated Financial Statements presented in human-readable format; and
  • Evaluating the appropriateness of the company’s use of iXBRL elements selected from the ESEF taxonomy and the creation of extension elements where no suitable element in the ESEF taxonomy has been identified;
  • Evaluating the use of anchoring of extension elements to elements in the ESEF taxonomy; and
  • Reconciling the iXBRL tagged data with the audited Consolidated Financial Statements.

Management is responsible for preparing an annual report that complies with the ESEF Regulation. This responsibility includes:

  • The preparing of the annual report in XHTML format;
  • The selection and application of appropriate iXBRL tags, including extensions to the ESEF taxonomy and the anchoring thereof to elements in the ESEF taxonomy, for all financial information required to be tagged using judgement where necessary; and
  • For such internal control as Management determines necessary to enable the preparation of an annual report that is compliant with the ESEF Regulation.

In our opinion, the annual report of ALK-Abelló A/S for the financial year 1 January to 31 December 2020 with the file name ALK-2020-12-31.zip is prepared, in all material respects, in compliance with the ESEF Regulation.

Hellerup, 10 February 2021

PricewaterhouseCoopers Statsautoriseret Revisionspartnerselskab
CVR No 3377 1231

Lars Baungaard
State Authorised Public Accountant
mne23331

Kim Tromholt
State Authorised Public Accountant
mne33251

Contents of the consolidated financial statements

Consolidated financial statementsAnnual report 2020ALK 53

Page
Income statement 54
Statement of comprehensive income 55
Cash flow statement 56
Balance sheet 57
Statement of changes in equity 58
Notes 58
1 Accounting policies 59
2 Significant accounting estimates and judgements 64
3 Revenue and segment information 65
4 Staff costs 66
5 Costs of sales 66
6 Research and development expenses 69
7 Sales and marketing expenses 69
8 Administrative expenses 69
9 Other operating items, net 70
10 Adjustments for non-cash items 70
11 Sale of companies and operations 70
12 Intangible assets 71
13 Property, plant and equipment 72
14 Deferred tax 74
15 Inventories 75
16 Trade receivables 75
17 Share capital and earnings per share 76
18 Pensions and similar liabilities 78
19 Mortgage debt and bank loans 79
20 Other provisions 79
21 Other payables 79
22 Changes in working capital 80
23 Contingent liabilities and commitments 83
24 Leases 84
25 Financial income and expenses 84
26 Tax on profit/(loss) for the year 84
27 Related parties 85
28 Events after the reporting period 85
29 Approval of financial statements 85
30 List of companies in the ALK Group 86
Definitions 88

Income statement

Consolidated financial statementsAnnual report 2020ALK 54

Amounts in DKKm Note 2020 2019
Revenue 3 3,491 3,274
Cost of sales 4-6,15 (1,463) (1,382)
Gross profit 2,028 1,892
Research and development expenses 4-6 (515) (466)
Sales and marketing expenses 4-6 (1,125) (1,210)
Administrative expenses 4-6 (237) (246)
Other operating items, net 7 (1) (2)
Operating profit/(loss) (EBIT) 150 (14)
Financial income 8 54 22
Financial expenses 1 (3) (1)
Profit/(loss) before tax (EBT) 101 (31)
Tax on profit/(loss) 9 (76) 19
Net profit/(loss) 25 (50) (82)
Earnings/(loss) per share (EPS) 17 2.29 (4.59)
Earnings/(loss) per share (DEPS), diluted 17 2.27 (4.59)

Statement of comprehensive income

Consolidated financial statementsAnnual report 2020ALK 55

Amounts in DKKm Note 2020 2019
Net profit/(loss) 25 (50) (82)
Items that will subsequently not be reclassified to the income statement:
Actuarial gains/(losses) on pension plans 18 (3) (37)
Tax related to actuarial gains/(losses) on pension plans 1 2
Items that will subsequently be reclassified to the income statement, when specific conditions are met:
Foreign currency translation adjustment of foreign affiliates (106) (105)
Tax related to other comprehensive income, that will subsequently be reclassified to the income statement 23 20
Total (107) (82)
Total comprehensive income/(loss) (56) (164)

Cash flow statement

Consolidated financial statementsAnnual report 2020ALK 56

Amounts in DKKm Note 2020 2019
Net profit/(loss) 25 (50) (82)
Adjustments
Adjustments for non-cash items 10 462 389
Changes in working capital 22 (154) (95)
Financial income, received 4 5
Financial expenses, paid (22) (14)
Income taxes, paid (net) (33) (84)
Cash flow from operating activities 301 132
Acquisitions of companies and operations* 11 - (20)
Sale of companies and operations 12 - (196)
Investments in intangible assets 13 (26) (23)
Investments in tangible assets 14 (196) (245)
Investments in other financial assets** (20) (147)
Cash flow from investing activities (242) (631)
Free cash flow 59 (499)
Sale of treasury shares 11 11
Exercised share options, paid 5 11
Repayment of lease liabilities 24 (24) (24)
Repayment of borrowings 19 (30) (16)
Cash flow from financing activities (57) (62)
Net cash flow (6) (82)
Cash beginning of year 316 296
Marketable securities beginning of year - 100
Cash and marketable securities beginning of year 316 396
Unrealised gain/(loss) on cash held in foreign currency and financial assets carried as cash and marketable securities (12) (6)
Net cash 308 316

Balance sheet

Amounts in DKKm 31 Dec. 2020 31 Dec. 2019 31 Dec. 2020 31 Dec. 2019
Assets Equity and liabilities
Non-current assets Equity
Intangible assets Share capital 111
Goodwill 452 172 Currency translation adjustment (125)
Other intangible assets 624 461 Retained earnings 3,167
Tangible assets Total equity 3,153
Land and buildings 1,023 325
Plant and machinery 921 442 Liabilities
Other fixtures and equipment 72 61 Non-current liabilities
Property, plant and equipment 269 330 Mortgage debt 19
in progress Bank loans 240
Property, plant and equipment 1,704 1,739 Pensions and similar liabilities 448
Other non-current assets 30 31 Lease liabilities 297
Receivables 697 620 Deferred tax liabilities 4
Deferred tax assets 168 160
Income tax receivables 895 826 Total non-current liabilities 1,008
Total non-current assets 3,223 3,247
Current liabilities
Current assets Mortgage debt 18
Inventories 1,093 1,056 Trade payables 74
Trade receivables 544 407 Lease liabilities 18
Receivables from group 27 21 Other provisions 32
companies Income taxes 3
Income tax receivables 1,029 934 Other payables 265
Other receivables 96 96 Deferred income 2,340
Prepayments 133 116
Cash 298 265 Total current liabilities 2,753
Total current assets 2,340 2,319 Total liabilities 3,761
Total assets 5,563 5,495 Total equity and liabilities 5,563

Consolidated financial statements • Annual report 2020 • ALK 57

Statement of changes in equity

Amounts in DKKm Share capital Currency translation adjustment Retained earnings Total equity Amounts in DKKm Share capital Currency translation adjustment Retained earnings Total equity
2020 2019
Equity at 1 January 111 (19) 3,084 3,176 Equity at 1 January 111 (42) 3,110 3,179
Net profit/(loss) - - - - Net profit/(loss) - - - (79)
Other comprehensive income/(loss) - 25 (107) (82) Other comprehensive income/(loss) - 23 (50) (27)
Total comprehensive income/(loss) - 25 (107) (82) Total comprehensive income/(loss) - 23 (50) (106)
Share-based payments - - - - Share-based payments - - - 11
Share options settled - - - - Share options settled - - - 39
Sale of treasury shares - - - - Sale of treasury shares - - - (24)
Tax related to items - - - - Tax related to items - - - 11
recognised directly in equity recognised directly in equity
Other transactions - 43 27 70 Other transactions - 53 59 112
Equity at 31 December 111 (125) 3,167 3,153 Equity at 31 December 111 (19) 3,084 3,176

Consolidated financial statements • Annual report 2020 • ALK 58

Notes to the consolidated financial statements

1 Accounting policies

The consolidated financial statements for the period 1 January to 31 December 2020 have been prepared in accordance with the International Financial Reporting Standards (IFRS) as adopted by the EU and in accordance with Danish disclosure requirements for listed companies. Additional Danish disclosure requirements for annual reports are imposed by the Statutory Order on Adoption of IFRS issued under the Danish Financial Statements Act.

The consolidated financial statements are presented in Danish kroner (DKK), which is considered the primary currency of the ALK Group’s activities and the functional currency of the parent company.

Basis of consolidation

The consolidated financial statements are prepared based on the financial statements of ALK-Abelló A/S and its subsidiaries. The consolidated financial statements are prepared as a consolidation of items of a uniform nature. The financial statements used for consolidation are prepared in accordance with the ALK Group’s accounting policies.

On consolidation, intra-group income and expenses, intra-group balances and dividends, and gains and losses arising on intra-group transactions are eliminated.

New standards effective from 1 January 2020

The ALK Group has implemented all new and amended standards and interpretations (IFRIC) which are effective for the financial year 2020. This has not resulted in any changes to the accounting policies of the ALK Group.

Business combinations

Newly acquired or newly established companies or operations are recognised in the consolidated financial statements from the date of acquisition or establishment. The date of acquisition is the date when control of the company actually passes to the ALK Group.

Companies sold or discontinued are recognised in the consolidated income statement up to the date of disposal. The date of disposal is the date when control of the company actually passes to a third party.

Acquisitions are accounted for using the purchase method, according to which the identifiable assets, liabilities and contingent liabilities of companies acquired are measured at fair value at the date of acquisition.

The cost of a company is the fair value of the consideration paid. If the final determination of the consideration is conditional on one or more future events, these are recognised at their fair value as of the acquisition date. As a general rule, adjustments to estimates of conditional consideration are recognised directly to the income statement.

Any excess of the cost of an acquired company over the fair value of the acquired assets, liabilities and contingent liabilities (goodwill) is recognised as an asset under intangible assets and tested for impairment at least once a year.

If the fair value of the acquired assets or liabilities subsequently proves different from the values calculated at the acquisition date, cost is adjusted for up to 12 months after the date of acquisition. Restructuring costs are only recognised in the takeover balance sheet if they represent a liability to the acquired company. The tax effect of revaluations is taken into account.

Any excess of the cost of an acquired company over the fair value of the acquired assets, liabilities and contingent liabilities (goodwill) is recognised as an asset under intangible assets and tested for impairment at least once a year.

Foreign currency translation

On initial recognition, transactions denominated in currencies other than DKK are translated at average exchange rates, which are an approximation of the exchange rates at the transaction date. Receivables and debt and other monetary items not settled at the balance sheet date are translated at the closing rate. Exchange rate differences between the exchange rate at the date of the transaction and the exchange rate at the date of payment or the balance sheet date, respectively, are recognised in the income statement under financial items.

Tangible assets and intangible assets, inventories and other nonmonetary assets acquired in foreign currency and measured based on historical cost are translated at the exchange rates at the transaction date.

On recognition in the consolidated financial statements of subsidiaries whose financial statements are presented in a functional currency other than DKK, the income statements are translated at average exchange rates for the respective months, unless these deviate materially from the actual exchange rates at the transaction dates. In that case, the actual exchange rates are used. Balance sheet items are translated at the exchange rates at the balance sheet date. Goodwill is considered to belong to the acquired company in question and is translated at the exchange rate at the balance sheet date.

Accounting policies are unchanged from last year except for the below mentioned.

This has not resulted in any changes to the accounting policies of the ALK Group.

New standards effective after 1 January 2021

A number of IFRS standards, amended standards and IFRIC interpretations, which are effective on or after 1 January 2021, have not been implemented.

The consolidated financial statements are presented on a historical cost basis, apart from certain financial instruments, which are measured at fair value. Otherwise, the accounting policies are as described below.

The disposal amount is measured as the fair value of the consideration received.

As a result, the individual figures in the cash flow statement cannot be reconciled directly to the income statement and the balance sheet.

  • Relates to final instalment payment for the acquisition of the operating assets of Allergy Laboratory of Oklahoma Inc. and Crystal Labs LLC in 2017.
    ** Relates to long-term prepayments to a strategic supplier.

The consolidated statement of cash flow is compiled using the indirect method.

The consolidated financial statements comprise the financial statements of ALK-Abelló A/S (the parent company) and companies (subsidiaries) controlled by the parent company. The parent company is considered to control a subsidiary when it holds, directly or indirectly, more than 50% of the voting rights, or is otherwise able to exercise or actually exercises a controlling influence, and has the right to variable returns from the entity.

Costs that can be attributed directly to the transfer of ownership are recognised in the income statement when they are incurred.

Cash and marketable securities year end

Year Cash Marketable securities
2020 298 316
2019 298 316
## Notes to the consolidated financial statements
### 1 Accounting policies – continued

Based on a preliminary assessment it is estimated that these standards and interpretations will have Gains or losses on disposal of subsidiaries Gains or losses on disposal of subsidiaries are stated as the difference between the disposal amount and the carrying amount of net assets including goodwill at the date of disposal, Exchange rate differences arising on the translation of foreign subsidiaries’ opening balance sheet items to the exchange rates at the balance sheet date and on the translation of the income statements from average exchange rates to exchange rates at the balance sheet date are recognised in other comprehensive income. is recognised in the income statement, and the tax expense relating to items recognised in other comprehensive income and directly in equity, respectively, is recognised in other comprehensive income or directly in equity.

Exchange rate countries when the deferred tax is expected to Revenue from the sale of goods is recognised in the income statement upon the control of the goods being transferred to the customer, i.e. when goods are delivered. Revenue is recognised by the ALK Group at a point in time. crystallise as current tax. Changes in deferred tax as a result of changed tax rates or rules are recognised in the income statement, in other comprehensive income or in equity, depending on where the deferred tax was originally recognised. Deferred tax related to equity transactions is recognised in equity. adjustments of deferred tax are recognised as part of the adjustment of deferred tax for the year. Foreign exchange rate adjustment of receivables or debt to subsidiaries which are considered part of the parent company’s overall investment in the subsidiary in question are also recognised in other comprehensive income in the consolidated financial statements. The ALK Group's customers have payment terms that reflect the customer type and the market in which sales take place, which typically varies from 0 to 180 days.

Current tax payable and receivable is recognised in the balance sheet as the expected tax on the taxable income for the year, adjusted for tax paid on account. Deferred tax assets, including the tax value of tax loss carry-forwards, are recognised in the balance sheet at the value at which the asset is expected to be realised, either through a set-off against deferred tax liabilities or as net assets to be offset against future positive taxable income. Deferred tax assets including the tax value of tax losses are recognised if it is probable that it can be utilised against future taxable income within a foreseeable future (5 years). This includes an assessment of the possibilities to utilise tax losses in the joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S). Revenue is measured as the fair value of the consideration received or receivable.

Share-based incentive plans The current tax charge for the year is calculated based on the tax rates and rules enacted at the balance sheet date. Share-based incentive plans (equity-settled share- based payments), which comprise share options and performance share units, are measured at the grant date at fair value and recognised in the income statement under the respective functions over the vesting period and offset in equity. Revenue is measured exclusive of VAT, taxes etc. charged on behalf of third parties and less any commissions and discounts in connection with sales. Uncertain tax position is recognised for those matters for which the tax determination is uncertain but it is considered probable that there will be a future outflow of funds to a tax authority (and a future inflow of funds from a tax authority). The uncertain tax positions are measured at the best estimate of the amount expected to become payable (and receivable).

Furthermore, revenue includes licence income and royalties from outlicensed products as well as up-front payments, milestone payments and services in connection with partnerships. These revenues are recognised in the income statement in accordance with the agreements and when the ALK Group obtains the right to the payments, which is at the point in time the subsequent sales occur or services have been delivered to the customer. The fair value of share options is determined using the Black & Scholes model. The fair value of performance share units is determined using the average share price (closing) 5 days after annual general meeting. At each balance sheet date, it is reassessed whether it is likely that there will be sufficient future taxable income for the deferred tax asset to be utilised.

Deferred tax is measured using the balance sheet liability method on all temporary differences between the carrying amount and the tax base of assets and liabilities. However, deferred tax is not recognised on temporary differences relating to the initial recognition of goodwill or the initial recognition of a transaction, apart from business combinations, and where the temporary difference existing at the date of initial recognition affects neither profit/loss for the year nor taxable income. The ALK Group settles the equity-settled share- based incentive plans in shares. However, the share option agreement entitles the ALK Group to demand cash settlement of the options. The ALK Group recognises share options, in case of cash settlement, as other liabilities and adjusts to fair value as from the time when the ALK Group has an obligation to settle in cash. The ALK Group recognises subsequent adjustment to fair value in the income statement under financial income or financial expenses. The parent company is included in a joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S) and its Danish subsidiaries. The tax charge for the year is allocated among the jointly taxed companies in proportion to the taxable incomes of individual companies, taking into account taxes paid.

Nonrefundable payments that are not attributable to subsequent research and development activities are recognised when the related right is obtained, whereas payments attributable to subsequent research and development activities are recognised over the term of the activities. When combined contracts are entered into, the elements of the contracts are identified and assessed separately for accounting purposes. Deferred tax is calculated based on the planned use of each asset and settlement of each liability, respectively. Deferred tax is measured using the tax rates and tax rules that, based on legislation enacted or in reality enacted at the balance sheet date, are expected to apply in the respective

Income statement

Tax

Revenue Tax on the profit for the year comprises the year’s current tax and changes in deferred tax. The tax expense relating to the profit/loss for the year The primary performance obligation of the ALK Group is the sale and delivery of own-manufactured goods and goods for resale for allergy treatment.

Cost of sales

The item comprises cost of sales and production costs incurred in generating the revenue for the Consolidated financial statements • Annual report 2020 • ALK 60 Notes to the consolidated financial statements 1 Accounting policies – continued year. Costs for raw materials, consumables, goods for resale, production staff and a proportion of production overheads, including maintenance and depreciation, amortisation and impairment of tangible assets and intangible assets used in production as well as operation, administration and management of factories are recognised in cost of sales and production costs. In addition, the costs and write-down to net realisable value of obsolete and slow-moving goods are recognised.

Administrative expenses

shorter useful life. Acquired intellectual property rights are written down to their recoverable amount where this is lower than the carrying amount, as

Balance sheet

The item comprises expenses incurred for management and administration, including expenses for administrative staff and management, office expenses and depreciation, amortisation and impairment losses on tangible assets and intangible assets used in administration.

Goodwill

described below. On initial recognition, goodwill is measured and recognised as the excess of the cost of the acquired company over the fair value of the acquired assets, liabilities and contingent liabilities, as described under ‘Business combinations’. Individual minor development projects running for short-term periods which fulfil the requirement in IFRS are capitalised under other intangible assets as described under ‘Research and development expenses’ and are measured at cost less

Other operating items

On recognition of goodwill, the goodwill amount is allocated to those of the ALK Group’s activities that generate separate cash flows (cash-generating units). The determination of cash-generating units is based on the ALK Group’s management structure and internal financial management and reporting. Other operating items comprise income and expenses of a secondary nature relative to the principal activities of the ALK Group.

accumulated amortisation and impairment.

Research and development expenses The item comprises research and development expenses, including expenses incurred for wages and salaries, amortisation, impairment of capitalised development projects in progress, and other overheads as well as costs relating to research partnerships. Research expenses are recognised in the income statement when incurred. Due to the long development periods and significant uncertainties in relation to the development of new products, including risks regarding clinical trials and regulatory approvals, it is the assessment that most of the ALK Group’s development expenses do not meet the capitalisation criteria in IAS 38, Intangible Assets.# Consolidated financial statements • Annual report 2020 • ALK 61

Notes to the consolidated financial statements

1 Accounting policies – continued

Consequently, development expenses are generally recognised in the income statement when incurred. Development expenses relating to individual minor development projects running for short-term periods and subject to limited risk are capitalised under other intangible assets. Intangible assets with indeterminable useful lives are not amortised, but are tested for impairment at least once a year. To the extent that the carrying amount of the assets exceeds the recoverable amount, the assets are written down to this lower amount, as described below. Financial items Financial items comprise interest receivable and interest payable, the interest element of lease payments, realised and unrealised gains and losses on securities, cash and marketable securities, liabilities and foreign currency transactions, mortgage amortisation premium/ allowance etc. and supplements/provisions under the on-account tax scheme. Goodwill is not amortised, but is tested for impairment at least once a year, as described below.

Tangible assets

Land and buildings, plant and machinery and other fixtures and equipment are measured at cost less accumulated depreciation and impairment. Land is not depreciated.

Intangible assets

Acquired intellectual property rights in the form of patents, brands, licenses, software, customer base and similar rights are measured at cost less accumulated amortisation and impairment. Interest expenses and income related to uncertain tax positions are recognised on the balance sheet as tax liabilities and tax assets respectively upon the receipt of ruling from the tax authorities and correspondingly reflected in the income statement as financial items net. Cost comprises the purchase price and any costs directly attributable to the acquisition and any preparation costs incurred until the date when the asset is available for use. Interest expenses on loans to finance the development of intangible assets are included in cost if they relate to the production period. Other borrowing costs are charged to the income statement. Lease assets are recognised at the commencement date of the contract if it is or contains a lease. Lease assets are recognised at cost less accumulated depreciation and impairment. Cost is defined as the lease liability adjusted for any lease payments made at or before the commencement date. Lease assets are depreciated on a straight-line basis over the lease term. Interest income and expenses are accrued based on the principal and the effective rate of interest. The effective rate of interest is the discount rate to be used on discounting expected future payments in relation to the financial asset or the financial liability so that their present value corresponds to the carrying amount of the asset or liability, respectively. The cost of software includes costs of instalment and direct salaries.

Sales and marketing expenses

The item comprises selling and marketing expenses, including salaries and expenses relating to sales staff, advertising and exhibitions, depreciation, amortisation and impairment losses on tangible assets and intangible assets used in the sales and marketing process as well as other indirect costs. Such acquired intellectual property rights are amortised on a straight-line basis over the expected useful lives of the assets, typically not exceeding 10 years. If the actual useful life is shorter than either the remaining life or the contract period, the asset is amortised over this Interest expenses on loans to finance the manufacture of tangible assets are included in cost if they relate to the production period. Other borrowing costs are recognised in the income statement. If the asset does not generate any cash flows independently of other assets, the recoverable amount is calculated for the smallest cash-generating unit that includes the asset. measured at fair value either through the income statement or through comprehensive income.

Inventories

The depreciation base is cost less the estimated residual value at the end of the useful life. The residual value, estimated at the acquisition date and reassessed annually, is determined as the amount the company expects to obtain for the asset less costs of disposal. Inventories are measured at cost determined under the FIFO method or net realisable value where this is lower. The recoverable amount is calculated as the higher of the fair value less costs to sell and the value in use of the asset or the cash-generating unit, respectively. In determining the value in use, the estimated future cash flows are discounted to their present value, using a discount rate reflecting current market assessments of the time value of money as well as risks that are specific to the asset or the cash-generating unit and which have not been taken into account in the estimated future cash flows.

Prepayments

Prepayments are recognised as an asset and comprise incurred costs relating to subsequent financial years. Prepayments are measured at cost. Cost comprises raw materials, goods for resale, and direct payroll costs as well as fixed and variable production overheads. Variable production overheads comprise indirect materials and payroll costs and are allocated based on predetermined costs of the goods actually produced. Fixed production overheads comprise maintenance of and depreciation on the machines, factory buildings and equipment used in the manufacturing process as well as the cost of factory management and administration. Fixed production overheads are allocated based on the normal capacity of the production plant.

Dividend

Dividend is recognised as a liability when adopted by the shareholders at the annual general meeting. The cost of an asset is divided into smaller components that are depreciated separately if such components have different useful lives.

Treasury shares

Acquisition and sales sums arising on the purchase and sale of treasury shares and dividends on treasury shares are recognised directly in retained earnings under equity. Assets are depreciated on a straight-line basis over their estimated useful lives as follows: If the recoverable amount of the asset or the cash-generating unit is lower than the carrying amount, the carrying amount is written down to the recoverable amount. For cash-generating units, the write-down is allocated in such a way that goodwill amounts are written down first, and any remaining need for write-down is allocated to other assets in the unit, although no individual assets are written down to a value lower than their fair value less costs to sell.

Buildings Plant and machinery Other fixtures and equipment
25-50 years 5-10 years 5-10 years

Pensions and similar liabilities

The ALK Group has entered into pension agreements and similar agreements with some of the ALK Group’s employees. Depreciation methods, useful lives and residual values are reassessed once a year. Tangible assets are written down to the recoverable amount, if lower, as described below. The net realisable value of inventories is calculated as the expected selling price less completion costs and costs incurred in making the sale. In respect of defined contribution plans, the ALK Group pays in fixed contributions to independent pension funds etc. The contributions are recognised in the income statement during the period in which the employee renders the related service. Payments due are recognised as a liability in the balance sheet.

Receivables

On initial recognition, receivables are measured at fair value, subsequently at amortised cost.

Impairment of tangible assets and intangible assets

Impairment write-downs are recognised in the income statement. If write-downs are subsequently reversed as a result of changes in the assumptions on which the calculation of the recoverable amount is based, the carrying amount of the asset or the cash-generating unit is increased to the adjusted recoverable amount, not, however, exceeding the carrying amount that the asset or cash-generating unit would have had, had the write-down not been made. Impairment of goodwill is not reversed. The carrying amounts of tangible assets and intangible assets with determinable useful lives are reviewed at the balance sheet date to determine whether there are any indications of impairment. If such indications are found, the recoverable amount of the asset is calculated to determine any need for an impairment write-down and, if so, the amount of the write-down. For intangible assets with indeterminable useful lives and goodwill, the recoverable amount is calculated annually, regardless of whether any indications of impairment have been found. Expected credit losses are measured based on historical data adjusted by forward-looking information. Forward-looking information includes assessment of the probability of default as well as consideration of various external sources of actual and economic information that is reasonable and supportable without undue cost or effort. In respect of defined benefit plans, the ALK Group is required to pay an agreed benefit in connection with the retirement of the employees covered by the plan, e.g. in the form of a fixed amount or a percentage of the salary at retirement. An impairment gain or loss is recognised in the income statement.

Other financial assets

For defined benefit plans, an annual actuarial assessment is made of the net present value of future benefits to which the employees have earned the right through their past service for the ALK On initial recognition, investments and other financial assets are measured at cost, corresponding to fair value.# Consolidated financial statements

Annual report 2020 • ALK 62

Notes to the consolidated financial statements

1 Accounting policies – continued

They are subsequently Receivables are written down when information indicates severe financial difficulties and that will have to be paid under the plan. The Projected Unit Credit Method is applied to determine net present value.

Mortgage debt Deferred income Cash flows from financing activities comprise Mortgage debt is recognised on the raising of a loan at cost, equalling fair value of the proceeds received, and net of transaction costs incurred. Subsequently, mortgage debt is measured at amortised cost. Deferred income comprises income received relating to subsequent financial years. Deferred income is measured at cost. changes to the parent company’s share capital and related costs as well as the raising and repayment of loans, instalments on interest-bearing debt, lease liabilities, purchase of treasury shares, and settlement of share options and payment of dividends. The net present value is calculated based on assumptions of the future development of salary, interest, inflation, mortality and disability rates.

Debt Trade payables, other payables, including sales discounts and rebates as well as debt to public authorities etc., are measured at amortised cost.

Lease liabilities The net present value of pension liabilities is recognised in the balance sheet, after deduction of the fair value of any assets attached to the plan, as either plan assets or pension liabilities, depending on whether the net amount is an asset or a liability, as described below. On initial recognition, lease liabilities are measured as the present value of future payments. The lease payments contain fixed payments less any lease incentives receivable and variable lease payments that depend on an index or a rate. Cash flows in currencies other than the functional currency are recognised in the cash flow statement using average exchange rates for the individual months if these are a reasonable approximation of the actual exchange rates at the transaction dates. If this is not the case, the actual exchange rates for the specific days in questions are used.

Other accounting information

Cash flow statement

On subsequent recognition, lease liabilities are measured at amortised cost. The difference between the present value and the nominal value of lease payments is recognised in the income statement over the term of the lease as a finance charge. The cash flow statement of the ALK Group is presented using the indirect method and shows cash flows from operating, investing and financing activities as well as cash and marketable securities at the beginning and at the end of the financial year.

If the assumptions made with respect to discount factor, inflation, mortality and disability are changed, or if there is a discrepancy between the expected and realised return on plan assets, actuarial gains or losses occur. These gains and losses concerning previous financial years are recognised in other comprehensive income. Cash and marketable securities comprise cash and short-term securities subject to an insignificant risk of changes in value less any overdraft facilities that are an integral part of the ALK Group’s cash management. If the interest rate cannot be determined in the agreement, the lease payments are discounted using the ALK Group’s incremental borrowing rate adjusted for the functional currency and length of the lease term. The lease liability is remeasured if or when the future payment or lease term changes. The cash effect of acquisitions and divestments is shown separately under cash flows from investing activities. In the cash flow statement, cash flows concerning acquired companies are recognised from the date of acquisition, while cash flows concerning divested companies are recognised until the date of divestment.

Segment reporting

Provisions

Based on the internal reporting used by the Board of Management to assess the results of operations and allocation of resources, the ALK Group has identified one operating segment ‘Allergy treatment’, which is in accordance with the way the activities are organised and managed. In addition, the disclosures in the financial statements include a breakdown of revenue by product line and a geographical breakdown of revenue and non-current assets.

Provisions are recognised when, as a consequence of a past event during the financial year or previous years, the ALK Group has a legal or constructive obligation, and it is likely that settlement of the obligation will require an outflow of the ALK Group’s financial resources. Short term lease expenses and low value assets are not recognised as part of lease liabilities. They are recognised in the income statement when incurred as an operating expense.

Provisions are measured as the best estimate of the costs required to settle the obligations at the balance sheet date. Provisions with an expected term of more than a year after the balance sheet date are measured at present value.

Other financial liabilities

Other financial liabilities, including bank loans and trade and other payables, are on initial recognition measured at fair value. The liabilities are subsequently measured at amortised cost.

Cash flows from investing activities comprise payments in connection with acquisition and divestment of companies and financial assets as well as purchase, development, improvement and sale of intangible and tangible assets.

Definitions and ratios

The key ratios have been calculated in accordance with generally accepted financial ratios applied by financial analysts. Definitions are shown on page 86.

Consolidated financial statements • Annual report 2020 • ALK 63

Notes to the consolidated financial statements

1 Accounting policies – continued

Reporting under the ESEF regulation

The Commission Delegated Regulation (EU) 2019/815 on the European Single Electronic Format (ESEF) (ESEF Regulation) has introduced a single electronic reporting format for the annual financial reports of issuers with securities listed on the EU regulated markets. As part of the tagging process financial statement line items are marked up to elements in the ESEF taxonomy. If a financial statement line item is not defined in the ESEF taxonomy, an extension to the taxonomy is created. Extensions have to be anchored to elements in the ESEF taxonomy, except for elements corresponding to subtotals. The tagging process is a process where iXBRL tags are applied to financial statement line items, etc. Taxonomy is an electronic dictionary of business reporting elements used to report business data. A taxonomy element is an element defined in a taxonomy that is used for the machine-readable labeling of information in an XBRL data record.

The ESEF Regulation sets out the following main requirements: (1) Issuers shall draw up and disclose their annual financial reports using the XHTML format; and (2) issuers that draw-up their primary consolidated financial statements in accordance with IFRS as endorsed by the EU shall tag those consolidated financial statements using inline eXtensible Business Reporting Language (iXBRL) and with effect from the 2022 annual report block-tag the notes to the consolidated financial statements. The annual report 2020 for the ALK Group submitted to the Danish Financial Supervisory Authority (The Officially Appointed Mechanisms) consists of the XHTML document together with some technical files all included in a ZIP file named "ALK-2020-12-31.zip".

Key definitions XHTML (eXtensible HyperText Markup Language) is a text-based markup language used to structure and mark up content such as text, images, and hyperlinks in documents that are displayed as Web pages in an updated standard Web browser like Chrome, Internet Explorer or Safari. The combination of the XHTML format with the iXBRL tags makes the annual financial reports both human-readable and machine-readable, thus enhancing accessibility, analysis and comparability of the information included in the annual financial reports. iXBRL tags (or Inline XBRL tags) are hidden meta-information embedded in the source code of an XHTML document in accordance with the Inline XBRL 1.1 specification, which enables the conversion of XHTML-formatted information into a machine-readable XBRL data record by appropriate software. iXBRL tags shall comply with the ESEF taxonomy, which is included in the ESEF Regulation and developed based on the IFRS taxonomy published by the IFRS Foundation.

Consolidated financial statements • Annual report 2020 • ALK 64

Notes to the consolidated financial statements

2 Significant accounting estimates and judgements

in the consolidated financial statements for information on goodwill impairment test. The indirect production costs capitalised under inventories amounted to DKK 377 million at the end of 2020 (2019: DKK 348 million). At 31 December 2020, the carrying amount of inventories is DKK 1,093 million (2019: DKK 1,056 million).

Management’s judgements are applied to assess the possible effect of exposures and the possible outcome of disputes or interpretational uncertainties when transfer pricing disputes with local tax authorities may occur. Dialogue with local tax authorities, tax advisors, business plans and knowledge of the business are key parameters for Management to estimate the tax assets and liabilities. In the preparation of the consolidated financial statements according to IFRS, Management is required to make certain estimates as many financial statement items cannot be reliably measured, but must be estimated. Such estimates comprise judgements made on the basis of the most recent information available at the reporting date.# Consolidated financial statements • Annual report 2020 • ALK 65

Notes to the consolidated financial statements

3 Revenue and segment information

Based on the internal reporting used by Management to assess profit and allocation of resources, the ALK Group has identified one operating segment “Allergy treatment” which complies with the organisation and management of the activities. Even though revenue within the operating segment “Allergy treatment” can be divided by product lines and markets, the main part of the activities within production, research and development, sales and marketing and administration are shared by the ALK Group as a whole.

Europe 2020 North America 2019 International markets 2020 Total 2019
Amounts in DKKm 2020 2019 2020 2019
SCIT/SLIT-drops 1,320 1,019 211 1,454
SLIT-tablets 735 275 85 306
Other products and services 85 78 266 24
Total revenue 2,370 1,372 562 1,784
2020 2019
Sale of goods 3,429 3,240
Royalties 58 34
Services 4 -
Total revenue 3,491 3,274

Of total revenue, DKK 83 million (2019: DKK 75 million) is derived from Denmark. The geographical information on markets is based on customer location.

The ALK Group’s non-current tangible and intangible assets are distributed among the following geographical markets:

Europe 2020 North America 2019 International markets 2020 Total 2019
Amounts in DKKm 2020 2019 2020 2019
Non-current tangible and intangible assets 1,629 1,616 695 800
2020 2019
Total 2,328 2,421

Of total non-current tangible and intangible assets, DKK 1,257 million relates to assets in Denmark (2019: DKK 1,227 million). The geographical information on assets is based on asset location.

Notes to the consolidated financial statements

4 Staff costs

Amounts in DKKm 2020 2019
Wages and salaries 1,342 1,303
Pensions, cf. note 18 110 111
Other social security costs, etc. 197 185
Share-based payments, cf. note 5 28 34
Total 1,677 1,633

Staff costs are allocated as follows:

2020 2019
Cost of sales 643 621
Research and development expenses 227 209
Sales and marketing expenses 544 555
Administrative expenses 208 205
Included in the cost of assets 55 43
Total 1,677 1,633

Employees

Average number (FTE) Number year end (FTE)
2020 2019
2,419 2,385
2,447 2,391

5 Share-based payments

The ALK Group has established long-term equity-based incentive plans linked to the creation of shareholder value and the fulfilment of strategic goals. The plans are established for the members of Board of Management and other key employees, reward long-term value creation and align to interests of the shareholders.

The incentive plans consist of share options and performance share units.

Ordinary incentive plans

The share options entitle the holder to acquire one existing B share of DKK 10 nominal value in the company per share option and the performance share units entitle the holder to receive one existing B share per performance share unit free of charge.

The vesting period for both share options and performance share units is three years after grant. Vesting is conditional upon certain targets being met and upon the participant not having resigned. Target achievement is met upon fulfilment of strategic key performance indicators. In case performance is below the threshold there will be no units vesting, and if above target, a multiplier is applied that can increase the vesting by up to 100%.

The exercise of share options is possible in the trading windows following the release of annual and interim reports conditional upon the share option holder not having resigned at the time of exercise. For performance share units, the final transfer of ownership takes place at vesting three years after the grant.

Remuneration to Management:

Board of Management
2020
Salaries 18
Special incentive plan 2018 1
Cash bonuses 16
Pensions 11
Expensed costs regarding share-based payments, cf. note 5 40
Total remuneration to Board of Management 86

Remuneration to Board of Directors:

2020 2019
Remuneration to Board of Directors 4 4
Total remuneration to Board of Management and Board of Directors 90 76

ALK’s special incentive plan is a one-time scheme designed to implement ALK’s growth strategy and consists of both share options and performance share units with a vesting period of three years. The value of the plan did not exceed 50% of the Executive’s 2018 annual base salary on the grant/allocation date. The special incentive plan is conditional upon strategic key performance indicators being attained, with a threshold value below which the plan will not pay out. If the result exceeds the threshold, a defined multiplier may increase the grant/allocation in ALK’s special incentive plan by up to 300%. However, the overall payout of the plan on the vesting date for the performance share units and on the exercise date for the share options can never exceed a total value of 300% of the recipient’s 2018 annual base salary. The special incentive plan was adopted at the annual general meeting in March 2018.

For both the ordinary incentive plan 2018 and the special incentive plan 2018, for a limited number of share options (45,441) and performance share units (11,458), the vesting can be increased by up to 300%.

Sign on plan, CEO

In connection with the employment of Carsten Hellmann in 2017, a CEO sign-on plan was launched.

At 31 December 2020, the carrying amount of goodwill is DKK 452 million (2019: DKK 461 million).

Inventories

The valuation of inventories includes Management’s assessment of the saleability of the finished goods, and the quality of raw materials to be used in the production process. If the expected sales price less any completion costs and costs to execute sales (net realisable value) of inventories is lower than the carrying amount, the inventories are written down to net realisable value. When assessing salability and net realisable value, Management uses estimates for future sales and related costs. It may be necessary to change previous estimates as a result of changes to the assumptions on which the estimates were based or due to supplementary information, additional experience or subsequent events. Similarly, the value of assets and liabilities often depends on future events that are somewhat uncertain. In that connection, it is necessary to set out e.g. a course of events that reflects Management’s assessment of the most probable course of events.

Further, work in progress and manufactured goods and goods for resale are measured at cost including indirect production costs. The indirect production costs are measured using a standard cost method. This is reviewed regularly to ensure reliable measurement of employee costs, capacity utilisation, cost drivers and other relevant factors. When including the indirect productions costs for capitalisation, Management makes estimates about cost of production, standard cost variances, cost drivers and capacity utilisation. Changes in these parameters may have a significant impact on the gross margin and the overall valuation of work in progress and manufactured goods and goods for resale.

Recoverable amount of goodwill

The assessment of whether goodwill is impaired requires a determination of the value in use of the cash-generating unit to which the goodwill amounts have been allocated. The determination of the value in use requires estimates of the expected future cash flow of the cash-generating unit and a reasonable discount rate. See note

Complying with tax rules

Complying with tax rules, when conducting business globally, can be complex as the interpretation of legislation and case law may change over time or may not always be clear. Tax Management is required to make an estimate in the recognition of deferred tax assets and liabilities. The ALK Group recognises deferred tax assets including the tax value of tax losses if it is probable that it can be utilised against future taxable income within a foreseeable future (5 years). This includes an assessment of the possibilities to utilise tax losses in the joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S) and based on forecasts with positive results for the coming years in relation to the joint taxation. This assessment includes estimates of future taxable income in ALK and other members of the joint Danish taxation scheme with the Lundbeck Foundation. The forecasts for ALK-Abelló A/S with increased positive results (EBT) is based on growth in revenue and earnings driven by SLIT-tablets.

At 31 December 2020, the ALK Group recognises uncertain tax positions as part of non-current tax and deferred tax. The actual outcome may deviate and depends on the result of litigation and settlements with the relevant local tax authorities.

At 31 December 2020, the value of the total net deferred tax asset is DKK 697 million (2019: DKK 616 million). It includes a net deferred tax asset in Denmark related to tax losses carried forward of DKK 322 million (2019: DKK 372 million).

Outsourced clinical trials

Clinical trials, which are outsourced to Clinical Research Organisations (“CROs”), take several years to complete. As such, Management is required to make estimates based on the progress and costs incurred to-date for the ongoing trials. Estimates are made in determining the amount of costs to be expensed during the period or recognised as prepayments or accruals on the balance sheet.

At 31 December 2020, DKK 135 million is recognised as accrued expenses (2019: DKK 105 million) and DKK 218 million as prepayments on the balance sheet (2019: DKK 166 million). In 2020, clinical trials expenses of DKK 154 million have been recognised in the income statement (2019: DKK 144 million).

In the consolidated financial statements for 2020, Management considers the following key accounting estimates and related judgements material to the assets and liabilities recognised in the consolidated financial statements.# Consolidated financial statements • Annual report 2020 • ALK 67

Notes to the consolidated financial statements

5 Share-based payments – continued

No KPIs were linked to the plan, which vested in January 2018 with an expiration date on 1 January 2024.

  • The expensed costs include DKK 3 million (2019: DKK 6 million) related to adjustment in the share options and performance share units expected to vest.
    **The total remuneration to the Board of Directors includes remuneration for participation in the Audit Committee DKK 385,000 (2019: DKK 350,000), the Remuneration Committee DKK 350,000 (2019: DKK 350,000) and the Scientific Committee DKK 150,000 (2019: DKK 150,000). The remaining remuneration relates to regular Board of Directors activities. Share options and performance share units are considered sufficiently covered by treasury shares.
Share options Weighted average exercise price Other Performance share units Weighted average exercise price Total units
2020
Outstanding at 1 January 98,263 12,130 25,383 904 1,332
Additions 15,552 104,020 14,898 94,869 198,889
Exercised/settled (3,377) 41,847 13,997 (4,309) -
Cancellations (21,758) (15,085) (36,843) (3,149) (12,774)
Expired (20,655) (38,570) (59,225) (932) -
Outstanding at 31 December 89,758 59,338 149,096 32,467 972
Total number of vested share options 98,263 62,293 160,556 42,513 904
Average remaining vested share options life at year end (years) 2.6
Exercise prices at year end (DKK) 783-1,372
2019
Outstanding at 1 January 104,020 14,898 94,869 198,889 10,509
Additions 15,552 104,020 14,898 94,869 198,889
Exercised/settled (3,377) 41,847 13,997 (4,309) -
Cancellations (21,758) (15,085) (36,843) (3,149) (12,774)
Expired (20,655) (38,570) (59,225) (932) -
Outstanding at 31 December 89,758 59,338 149,096 32,467 972
Total number of vested share options 98,263 62,293 160,556 42,513 904
Average remaining vested share options life at year end (years) 2.6
Exercise prices at year end (DKK) 783-1,372
  • The expensed costs include DKK 3 million (2019: DKK 6 million) related to adjustment in the share options and performance share units expected to vest.
    **The total remuneration to the Board of Directors includes remuneration for participation in the Audit Committee DKK 385,000 (2019: DKK 350,000), the Remuneration Committee DKK 350,000 (2019: DKK 350,000) and the Scientific Committee DKK 150,000 (2019: DKK 150,000). The remaining remuneration relates to regular Board of Directors activities. Share options and performance share units are considered sufficiently covered by treasury shares.

The Board of Directors decided for two trading windows in 2020 to settle share options by cash and a total of 24,945 share options were exercised and total cash payments amounted to DKK 24 million. For two trading windows the Board of Directors decided to settle share options by shares and a total of 11,898 share options were exercised. The Board of Directors decided for one trading window in 2019 to settle share options by cash and a total of 41,125 share options were exercised and total cash payments amounted to DKK 24 million. For three trading windows the Board of Directors decided to settle share options by shares and a total of 18,100 share options were exercised.

5 Share-based payments – continued

Outstanding share options and performance share units have the following characteristics:

Share options Performance share units
Average exercise price
Exercise period (years) 3 6
Vested as per 9 10
Plan 1 4
2014 Plan 7 11
2015 Plan 12 5
2016 Plan 100
2017 Sign on plan, CEO 4,025 1 Mar 2017
2017 Plan 5,050 1 Mar 2018
2018 Plan 17,068 1 Mar 2019
2018 Plan – special plan 6,224 1 Jan 2018
2019 Plan 30,873 1,025
2020 Plan 43,341 1 Mar 2020
23,738 795
18,677 1 Mar 2021
795 1 Mar 2021
856 1,100
1 Mar 2017 1,127
1 Mar 2018 1,442
1 Mar 2019 15,607
1 Jan 2018 8,708
1 Mar 2020 13,241
793 11,314
1 Mar 2021
793
1 Mar 2021
1,127
1 Mar 2022
1,442
1 Mar 2023
Total 29 39

Expensed in the income statement:

Amounts in DKKm 2020 2019
Cost of sales 1 5
Research and development expenses 4 13
Sales and marketing expenses
Administrative expenses
Financial expenses
Plan Units DKK Units
2014 Plan 100 4,025 5,050
2015 Plan 17,068 6,224 30,873
2016 Plan 43,341 23,738 18,677
2017 Sign on plan, CEO 795 856 1,100
2017 Plan 1 Mar 2017 1 Mar 2018 1 Mar 2019
2018 Plan 1 Jan 2018 1 Mar 2020 793
2018 Plan – special plan 1 Mar 2021 793 1,127
2019 Plan 1 Mar 2021 1,442 15,607
2020 Plan 1 Mar 2022 8,708 13,241
1 Mar 2023 11,314

In 2020, the total cost of share-based payments included a financial expense of DKK 1 million due to the exercise and cash settlement of share options plans (2019: DKK 5 million) and DKK 5 million related to adjustment in the share options and performance share units expected to vest (2019: DKK 13 million).

Fair value of share options and performance share units granted:

Share options Performance share units
Outstanding at 31 December 149,096 48,870

Fair value at grant date is measured in accordance with the Black & Scholes model for valuation of share options, using the following assumptions:

2020 Plan 2019 Plan
Average share price (DKK) 1,372 1,072
Expected exercise price (DKK)* 1,477 1,154
Expected volatility rate** 34% p.a. 32% p.a.
Expected option life 4 years 4 years
Expected dividend per share - -
Risk-free interest rate -0.01% p.a. -0.44% p.a.
Calculated fair value of granted share options (DKK) 328 233
  • The exercise price is equivalent to the average market price of the share for the five trading days immediately preceding the date of grant and is increased by 2.5% p.a. and reduced by dividends paid.
    ** The expected volatility rate is based on the historical volatility.

Performance share units have been granted at the average market price of the share for the five trading days immediately preceding the date of grant at DKK 1,372 per share (2019: DKK 1,072 per share).

Consolidated financial statements • Annual report 2020 • ALK 69

Notes to the consolidated financial statements

6 Depreciation, amortisation and impairment

Amounts in DKKm
2020
Depreciation, amortisation and impairment allocation:
Cost of sales 152
Research and development expenses 26
Sales and marketing expenses 35
Administrative expenses 43
Total 245

Impairment amounts to DKK 38 million (2019: DKK 30 million), of which DKK 16 million relate to tangible assets (2019: DKK 30 million) and DKK 22 million relate to intangible assets (2019: DKK 0).
The impairment of tangible assets is related to impairment of production equipment with no recoverable amount after impairment. The impairment is recognised as cost of sales.
The impairment of intangible assets is related to impairment of acquired intellectual property rights of DKK 13 million and software of DKK 9 million with no recoverable amount after impairment. The impairment is recognised with DKK 19 million as research and development expenses and DKK 3 million as cost of sales.

7 Other operating items, net

Amounts in DKKm
2020
In 2020, other operating items include other operating expenses of DKK 1 million related to sale of production equipment.
In 2019, other operating items included other operating income of DKK 16 million of which income of DKK 15 million related to sale of the North American Veterinary Business Unit effective from 30 November 2019. See note 11 for further information.

8 Financial income and expenses

Amounts in DKKm
2020
Interest income 5
Financial income from financial assets measured at amortised cost 5
Interest income on uncertain tax positions, net -
Interest income on marketable securities 1
Currency gains, net 5
Total financial income 22
Interest expenses* 30
Financial expenses from financial liabilities measured at amortised cost 39
Interest expenses on uncertain tax positions, net 4
Currency losses, net 54
Total financial expenses 39
  • Includes interest expenses related to leasing of DKK 8 million (2019: DKK 8 million).

Consolidated financial statements • Annual report 2020 • ALK 70

Notes to the consolidated financial statements

9 Tax on profit/(loss) for the year

Amounts in DKKm
2020
Current income tax 117
Adjustment of deferred tax (3)
Prior year adjustments, income tax (32)
Prior year adjustments, deferred tax 19
Total 76

Tax related to equity comprises an income of DKK 43 million (2019: income of DKK 27 million) and other comprehensive income comprises an income of DKK 2 million (2019: income of DKK 8 million). Out of the ALK Group’s total revenue of DKK 3,274 million in 2019, DKK 20 million was attributable to the North American Veterinary Business Unit.

11 Sale of companies and operations

No companies or operations were sold in 2020.
Effective 30 November 2019, ALK sold its North American Veterinary Business Unit to Spectrum Veterinary LLC. The operation was previously an integrated part of ALK’s subsidiaries in North America.

The North American Veterinary Business Unit specialises in products for veterinary use.

Amounts in DKKm
2019
Profit/(loss) before tax 101
Sales price 22
Income tax, tax rate of 22% (2019: 22%) (31)
Effect of deviation of foreign subsidiaries’ tax rate relative to Danish tax rate (7)
Carrying value of sold net assets 46
Patents, trademarks and rights 3
Goodwill 4
Plant and machinery 7
Sold net assets 3
Transaction cost (2)
Net gain on sales of companies and operations included in other operating income in the income statement 1
Adjustment of deferred tax due to coming year change of tax rate 1
Other taxes and adjustments 14
Change in valuation of net tax assets (8)
Prior year adjustments, income tax 19
Prior year adjustments, deferred tax 76
Tax on profit/(loss) for the year (22)
8
## Notes to the consolidated financial statements

10 Adjustments for non-cash items

Amounts in DKKm 2020 2019
Tax on profit/(loss) 76 49
Financial income and expenses 19 17
Share-based payments 29 39
Reversal of accounting gain on sale of companies and operations - (14)
Depreciation, amortisation and impairment 255 245
Other adjustments* 73 63
Total 462 389
  • Other adjustments include mainly provision for transition period for the Danish Holiday Act of DKK 39 million (2019: DKK19 million) and non-cash transactions related to the divestment of ALK’s part-share of a formulation production line for tablets to production partner Catalent of DKK 37 million (2019: DKK 24 million).

12 Intangible assets

12 Intangible assets – continued

Patents, trademarks and rights

Amounts in DKKm 2020 2019
Goodwill 483 488
Software 400 353
Other 251 277
Total 1,134 1,118

Goodwill is related to acquisition of companies in previous years and is recognised as the excess of the cost of an acquired company over the fair value of the acquired assets, liabilities and contingent liabilities.

Goodwill

Amounts in DKKm 2020 2019
Cost beginning of year 1,374 1,399
Currency adjustments (20) 12
Additions 26 20
Disposals (33) (29)
Transfer to/from other groups - (8)
Cost year end 1,347 1,384
Amortisation and impairment beginning of year 231 163
Currency adjustments (7) (1)
Amortisation for the year 69 59
Amortisation on disposals (9) (4)
Impairment for the year, cf. note 6 - -
Amortisation and impairment year end 284 217
Carrying amount year end 1,063 1,167

Goodwill has been subject to an impairment test, which has been submitted to the Audit Committee for subsequent approval by the Board of Directors. The impairment test performed in 2020 revealed no need for impairment of goodwill.

Goodwill has been tested at an aggregated level. The ALK Group is considered as one cash-generating unit as the individual companies and business units in the ALK Group cannot be evaluated separately due to the value-adding processes are generated across corporations and entities.

In the calculation of the value in use of the cash-generating unit, future free net cash flow is estimated based on Board of Directors-approved financial forecast in line with the ALK Group’s strategy. The budget and the strategy plans are based on specific future business initiatives for which the risks relating to key parameters have been assessed and recognised in estimated future free cash flows. The key parameters in the calculation of the value in use are revenue, earnings, working capital, capital expenditure, discount rate and the preconditions for the terminal value. Estimates are based on historical data and expectations on future changes in the markets and products. These expectations are based on a number of assumptions including expected product launches, volume forecasts, price information and profitability of both the ALK Group’s business as well as geographical expansions.

For financial years after the five year forecast period (2021-2025), the cash flows in the most recent period have been extrapolated adjusted for a growth factor of 1.5% (2019: 1.5%) during the terminal period.

The discount rate used is 10% pre-tax and 7.5% after tax (2019: 10% pre-tax and 7.5% after tax).

The calculated value in use shows that future earnings and cash flows fully support the carrying amount of total net assets, including goodwill.

Software

Amounts in DKKm 2020 2019
Cost beginning of year 475 283
Currency adjustments (2) 2
Additions 23 216
Disposals (7) (3)
Transfer to/from other groups (22) (11)
Cost year end 461 487
Amortisation and impairment beginning of year 208 152
Currency adjustments (7) (2)
Amortisation for the year 22 11
Amortisation on disposals (6) (3)
Impairment for the year, cf. note 6 - -
Amortisation and impairment year end 207 157
Carrying amount year end 254 330

Other intangible assets cover minor finished development projects and development projects in progress including software development projects.

Other

Amounts in DKKm 2020 2019
Cost beginning of year 231 173
Currency adjustments (1) (1)
Additions 23 46
Disposals (2) (28)
Sale of companies and operations, cf. note 11 - (17)
Transfer to/from other groups - (2)
Cost year end 251 273
Amortisation and impairment beginning of year 83 62
Currency adjustments (1) (1)
Amortisation for the year 11 5
Amortisation on disposals (3) (1)
Amortisation on sale of companies and operations, cf note 11 - (4)
Impairment for the year, cf. note 6 - -
Amortisation and impairment year end 90 61
Carrying amount year end 161 212

13 Property, plant and equipment

13 Property, plant and equipment – continued

Property, plant and equipment Land and buildings* Plant and machinery Fixtures and equipment Assets in progress Other Total
Amounts in DKKm
2020
Cost beginning of year 1,533 807 244 421 3,005 3,005
Initial application of IFRS 16 beginning of year 903 167 266 1 1,337 1,337
Lease contract modifications 9 - 12 - 21 21
Additions 177 942 125 176 1,420 1,420
Currency adjustments (23) (14) (4) (9) (50) (50)
Disposals (1) (201) (18) (24) (244) (244)
Sale of companies and operations, cf. note 11 50 - 14 (69) (5) (5)
Transfer to/from other groups (4) 32 - - 28 28
Cost year end 2,684 1,635 575 395 4,417 4,417
Depreciation and impairment beginning of year 510 482 183 91 1,266 1,266
Currency adjustments (13) (15) (3) (1) (32) (32)
Depreciation for the year 521 500 184 72 1,277 1,277
Depreciation of disposals (1) (33) (14) (16) (64) (64)
Depreciation on sale of companies and operations, cf. note 11 (1) - (1) - (2) (2)
Impairment for the year, cf. note 6 19 - - - 19 19
Depreciation and impairment year end 1,035 934 359 146 2,444 2,444
Carrying amount year end 1,649 701 216 249 1,973 3,828
  • Land and buildings include buildings on land leased from Scion DTU A/S, Hørsholm in Denmark. The leases are open-ended and the estimated lease terms are 15 years.

Property, plant and equipment

Amounts in DKKm Land and buildings* Plant and machinery Fixtures and equipment Assets in progress Other Total
2019
Cost beginning of year 1,339 903 241 364 2,847 2,847
Initial application of IFRS 16 beginning of year 167 266 1 2 436 436
Lease contract modifications 1 12 - - 13 13
Additions 21 360 12 125 518 518
Currency adjustments (18) (67) - - (85) (85)
Disposals (153) (201) (22) (7) (383) (383)
Sale of companies and operations, cf. note 11 (4) - - (4) (8) (8)
Transfer to/from other groups (69) - - - (69) (69)
Cost year end 1,395 967 232 479 2,759 5,831
Depreciation and impairment beginning of year 461 521 189 92 1,263 1,263
Currency adjustments 3 3 - - 6 6
Depreciation for the year 572 500 184 72 1,328 1,328
Depreciation of disposals (197) (56) (119) (22) (394) (394)
Depreciation on sale of companies and operations, cf. note 11 (1) - - - (1) (1)
Impairment for the year, cf. note 6 11 - - - 11 11
Depreciation and impairment year end 849 972 254 142 2,113 3,515
Carrying amount year end 546 (5) (22) 337 646 1,507
  • Land and buildings include buildings on land leased from Scion DTU A/S, Hørsholm in Denmark. The leases are open-ended and the estimated lease terms are 15 years.

Specification of right-of-use assets:

Property, plant and equipment Land and buildings Plant and machinery Fixtures and equipment Other Total
Amounts in DKKm
2020
Cost beginning of year 293 2 - 2 297
Additions 10 - - - 10
Lease contract modifications - - - - -
Currency adjustments (9) - - - (9)
Disposals (1) - - - (1)
Cost year end 293 2 - 2 297
Depreciation beginning of year 35 1 - 1 37
Depreciation for the year, cf. note 24 32 - - - 32
Depreciation of disposals (2) - - - (2)
Depreciation year end 65 1 - 1 67
Carrying amount year end 228 1 - 1 230

Specification of right-of-use assets:

Property, plant and equipment Land and buildings Plant and machinery Fixtures and equipment Other Total
Amounts in DKKm
2019
Cost beginning of year 114 10 - 10 134
Initial application of IFRS 16, beginning of year 266 28 - - 294
Additions 1 - - - 1
Lease contract modifications - - - - -
Currency adjustments (9) - - - (9)
Disposals (114) - - - (114)
Cost year end 257 38 - 10 305
Depreciation beginning of year 36 1 - 1 38
Depreciation for the year, cf. note 24 35 - - - 35
Depreciation of disposals (32) - - - (32)
Depreciation year end 39 1 - 1 41
Carrying amount year end 218 37 - 9 264

14 Deferred tax

Amounts in DKKm Tax losses carried forward Intangible assets Tangible assets Liabilities Total
2020
Carrying amount beginning of year 11 (100) 206 (17) 117
Adjustment to prior years’ deferred tax - (1) (2) - (3)
Adjustment of receivables from group companies - - 1 - 1
Currency adjustments (1) (19) - - (20)
Recognised in the income statement, net (5) 2 36 2 35
Change in valuation of net tax assets (2) - - - (2)
Recognised in other comprehensive income, net - 1 1 - 2
Recognised in equity, net (share-based payments) - - - 1 1
Carrying amount year end 3 (117) 242 (14) 114
Amounts in DKKm Tax losses carried forward Intangible assets Tangible assets Liabilities Total
2019
Carrying amount beginning of year 31 (46) 166 41 192
Impact from initial application of IFRIC 23 6 - 17 - 23
Adjustment to prior years’ deferred tax - (1) - - (1)
Adjustment of receivables from group companies - - 10 - 10
Adjustment of deferred tax due to coming year change of tax rate - - (25) - (25)
Recognised in the income statement, net (3) 9 43 26 75
Change in valuation of net tax assets - (1) - - (1)
Recognised in other comprehensive income, net - 46 26 8 80
Recognised in equity, net (share-based payments) - - - (3) (3)
Carrying amount year end 34 48 231 72 385

Deferred tax consists of deferred tax assets of DKK 697 million (2019: DKK 620 million) and deferred tax liabilities of DKK 0 (2019: DKK 4 million). The ALK Group recognises deferred tax assets including the tax value of tax losses if it is probable that it can be utilised against future taxable income within a foreseeable future (5 years). This includes an assessment of the possibilities to utilise tax losses in the joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S). See note 2 for further information.# Consolidated financial statements • Annual report 2020 • ALK 75

Notes to the consolidated financial statements

15 Inventories


Amounts in DKKm 2020 2019
Raw materials* 209 214
Work in progress 438 447
Manufactured goods and goods for resale 446 395
Total 1,093 1,056


Amount of write-down of inventories during the year: 45 (2019: 53)
Amount of reversal of write-down of inventories during the year**: 10 (2019: 21)

The total cost of materials included in cost of sales amounted to DKK 357 million (2019: DKK 326 million).
The net carrying amount of inventory not expected to be sold in 2021 is estimated at DKK 225 million (2020: DKK 263 million).

Loss allowance: Amounts in DKKm 2020 2019
Balance beginning of year 12 11
Change in allowances during the year 6 7
Realised losses during the year (3) (6)
Loss allowance, year end 15 12
  • A minor part of ALK’s raw material inventory contains biological assets from agricultural activities. Due to missing market on which a fair value can be established these products are not valuated.
    ** Reversal of provision for slow moving items, sold in 2020.

16 Trade receivables

Amounts in DKKm Days past due 2020 2019
Not due 475 358
<180 days 71 51
180-360 50 4
>360 days 10 2
Total 559 419
Average expected credit loss rate 2020 2019
Trade receivables (gross) 1% 475 0% 358
Loss allowance 8% 71 8% 51
14% 50 50% 4
50% 10 83% 2
Total 559 419
Trade receivables (net) 470 357
Loss allowance: Amounts in DKKm 2020 2019
Balance beginning of year 5 1
Change in allowances during the year 8 4
Realised losses during the year 6 2
Loss allowance, year end 15 6

Loss allowance for doubtful trade receivables is based on an individual assessment of the receivables.

Consolidated financial statements • Annual report 2020 • ALK 76

Notes to the consolidated financial statements

17 Share capital and earnings per share

Amounts in DKKm 2020 2019
Share capital
A shares 9 9
AA shares 1 1
B shares 101 111
Total nominal value 111 121

Each A and AA share carries 10 votes, whereas each B share carries 1 vote. AA shares no longer held by individuals or legal entities other than the Lundbeck Foundation (Lundbeckfond Invest A/S) or companies which are group affiliated with the Lundbeck Foundation, cf. the definition of groups in section 6 of the Danish Companies Act, or in the event that a company which holds AA shares is no longer group affiliated with the Lundbeck Foundation, such AA shares shall be transferred to the B share capital.

Amounts in DKKm Units 2020 2019
Treasury shares beginning of year (B-shares) units 240,694 263,203
Sale of treasury shares units (27,821) (22,509)
Treasury shares year end (B-shares) units 212,873 240,694
Proportion of share capital year end 1.9% 2.1%
Nominal value year end 2.1 2.4

According to a resolution passed by the parent company at the annual general meeting, the parent company is allowed to purchase treasury shares, equal to 10% of the share capital. The parent company has purchased treasury shares in connection with the issuance of share-based incentive plans.

At year end 2020 the amount of A shares was 920,760 (2019: 920,760), AA shares 92,076 (2019: 92,076) and B shares 10,128,360 (2019: 10,128,360). All shares have a nominal value of DKK 10.

Earnings per share

The calculation of earnings per share is based on the following:

Number in units: 2020 2019
Average number of issued shares 11,141,196 11,141,196
Average number of treasury shares (225,139) (252,533)
Average number of shares used for calculation of earnings/(loss) per share 10,916,057 10,888,663
Average dilutive effect of outstanding share options 78,328 61,114
Average number of shares used for calculation of diluted earnings/(loss) per share 10,994,385 10,949,777
Earnings/(loss) per share (EPS) 2020 2019
Earnings/(loss) per share 2.29 (4.59)
Earnings/(loss) per share, diluted (DEPS) 2.27 (4.59)

18 Pensions and similar liabilities

The ALK Group has entered into defined contribution plans as well as defined benefit plans. In defined contribution plans, the ALK Group is obliged to pay a certain contribution to a pension fund or the like but bears no risks regarding the future development in interest, inflation, mortality, disability rates etc. regarding the amount to be paid to the employee.

The ALK Group sponsors defined benefit plans for qualifying employees of its subsidiaries in Germany, France and Switzerland. The defined benefit plans guarantee employees a certain level of pension benefits for life. The pension is based on seniority and salary at the time of retirement. The ALK Group bears the risks regarding the future development in interest, inflation, mortality, disability rates etc. regarding the amount to be paid to the employee.

Amounts in DKKm 2020 2019
Costs related to defined contribution plans 86 84
Costs related to defined benefit plans 24 27
Total 110 111
Amounts in DKKm 2020 2019
Present value of funded pension obligations 532 394
Fair value of plan assets (20) (13)
Funded pension obligations, net 512 381
Present value of unfunded pension obligations 268 257
Pension obligations 780 638
Anniversary liabilities 12 11
Indemnity fund - -
Other liabilities* 58 345
Pension obligations and similar liabilities, year end 850 994
  • Other liabilities include liability related to the transition period for the Danish Holiday Act of DKK 58 million (2019: DKK 19 million).

Plan assets consist of assets placed in pension companies. Assets are placed in investments classified as other assets than shares, bonds and property by the pension companies, and are not measured at quoted prices.

The weighted average duration of the pension obligations is 19.64 years (2019: 20.12 years).

Consolidated financial statements • Annual report 2020 • ALK 77

Notes to the consolidated financial statements

18 Pensions and similar liabilities – continued

Amounts in DKKm 2020 2019
Movements in the fair value of the plan assets in the current year
Opening fair value of plan assets 13 11
Contribution from plan participants 1 1
Benefits paid (1) (1)
Closing fair value of plan assets 13 11
Amounts in DKKm 2020 2019
Movements in present value of unfunded pension obligations in the current year
Opening present value of unfunded pension obligations 257 211
Current service costs 8 11
Interest costs 7 6
Actuarial (gains)/losses from changes in financial assumptions 37 3
Actuarial (gains)/losses arising from experience adjustments (3) (2)
Actuarial (gains)/losses arising from demographic adjustments (2) (3)
Benefits paid (1) (1)
Closing present value of unfunded pension obligations 296 257
Amount recognised as staff expenses in the income statement 2020 2019
Current service costs 10 11
Net interest expense 2 4
Total 12 15
Amount recognised in comprehensive income in respect of defined benefit plans 2020 2019
Actuarial (gains)/losses 37 3
Total 37 3
Amounts in DKKm 2020 2019
Movements in the present value of the defined benefit obligation in the current year
Opening defined benefit obligation 20 15
Current service costs 2 1
Actuarial (gains)/losses from changes in financial assumptions - -
Actuarial (gains)/losses arising from experience adjustments (1) (1)
Benefits paid (2) -
Currency translation adjustment 1 -
Closing defined benefit obligation 20 20

The principal assumptions used for the actuarial valuations:

2020 2019
Discount rate range of 0.2% - 0.8% (weighted average rate) 0.7% 0.8%
Expected future rate of salary increase range of 1% - 2.5% (weighted average rate) 2.4% 2.0%

Assumed life expectations on retirement age for current pensioners (years based on weighted average)*:

Males Females
2020 21.1 22.3
2019 21.6 23.2

Assumed life expectations on retirement age for current employees (future pensioners) (years based on weighted average)*:

Males Females
2020 24.8 26.2
2019 25.4 27.3

Sensitivity analysis:
Significant actuarial assumptions for determining the defined benefit obligation

Discount rate, effect in case of increase in range of 0.25% - 1%** Discount rate, effect in case of decrease in range of 0.25% - 1%** Salary, effect in case of 0.25% - 0.5% increase** Salary, effect in case of 0.25% - 0.5% decrease** Life expectancy, effect in case of increase by 1 year* Life expectancy, effect in case of decrease by 1 year*
2020 (43) 56 (41) 54 (5) 12
2019 (12) 3 (4) 11 (12) (11)
  • Based on national statistics for mortality.
    ** Based on actuarial reports with different rates.

The expected contribution for 2021 for the defined benefit plans is DKK 12 million (2020: DKK 8 million).
The most recent actuarial valuations of the defined benefit liability were carried out by external independent actuary agents at 31 December 2020. In 2020, a pension plan has been reclassified and comparative figures have been adjusted accordingly.

Consolidated financial statements • Annual report 2020 • ALK 78

Notes to the consolidated financial statements

19 Mortgage debt and bank loans

Carrying amount Fair value Acquisition Restructuring programs* of operating assets** Other provisions***
Amounts in DKKm 2020 2019 2020 2019 2020
Total 18 18 71 71 18

Debt to mortgage credit institutions secured by real property
Mortgage debt is due as follows*:

2020 2019
Within 1 year 3 3
From 1-5 years 15 15
After 5 years - -
Total 18 18

Bank loans
Bank loans are due as follows:

2020 2019
Within 1 year - 446
From 1-5 years 446 -
After 5 years - -
Total 446 446

Mortgage debt and bank loans are recognised accordingly:

2020 2019
Non-current liabilities 18 18
Current liabilities 446 446
Total 464 464

20 Other provisions

Other provisions beginning of year Used during the year* Reversals during the year Other provisions, year end***
Amounts in DKKm 2020 2019 2020
Restructuring programs* 4 3 (1)
Operating assets** 18 18 -
Other provisions*** 71 72 (20)
Total 93 93 (21)

Other provisions are recognised as follows:

Other provisions beginning of year Provisions made during the year Used during the year** Reversals during the year Other provisions, year end
Amounts in DKKm 2020 2019 2020 2019
Current liabilities 3 3 16 5
Non-current liabilities 70 70 28 19
Total 73 73 44 24
## Notes to the consolidated financial statements

21 Other payables

Amounts in DKKm 2020 2019
Rebates and commissions 243 253
Salaries, holiday payments etc. 242 177
VAT and other taxes 109 286
Other 880 65
Total 1,474 781

22 Changes in working capital

Amounts in DKKm 2020 2019
Change in inventories (69) (159)
Change in receivables and prepayments 74 (54)
Change in short-term payables (200) 159
Total (195) (54)

23 Contingent liabilities and commitments

Contingent liabilities

In the ordinary course of business, the ALK Group is involved in certain claims, disputes etc. In the opinion of Management, settlement or continuation of pending claims and other disputes will have no material impact on the ALK Group’s financial position.

The ALK Group operates in a wide variety of jurisdictions, in some of which the tax law is subject to varying interpretations and potentially inconsistent enforcement. As a result, there can be practical uncertainties in applying tax legislation to the ALK Group’s activities. Whilst the ALK Group considers that it operates in accordance with applicable tax law, there are potential tax exposures in respect of its operations, the impact of which cannot be reliably estimated, but could be material.

Joint taxation scheme

ALK-Abelló A/S is included in a joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S) and its Danish subsidiaries. The Danish companies are joint and several liable for the joint taxation liability. The joint taxation liability covers income taxes and withholding taxes on dividends, royalties and interest. The joint taxation liability is capped at an amount equal to the share of the capital of the company directly or indirectly owned by the ultimate parent company.

Commitments

Amounts in DKKm 2020 2019
Land and buildings provided as security vis-à-vis for mortgage debt amount to DKK 197 million (2019: DKK 209 million) out of mortgage debt of DKK 258 million (2019: DKK 277 million).
Change of control
The ALK Group's credit facilities are subject to standard change of control clauses according to which the lender has the right to cancel the commitment and demand repayment of outstandings.

24 Leases

Leases in the income statement

Amounts in DKKm 2020 2019
Expenses from short-term leases 1 4
Expenses from low-value assets (including cars) 19 18
Depreciation of right-of-use assets, cf. note 13 36 36
Interest expenses on lease liabilities 8 8
Total 64 66

Cash outflow related to lease agreements was DKK 38 million (2019: DKK 37 million).

Lease liabilities

Amounts in DKKm 2020 2019
Lease liabilities expire as follows:
Within 1 year 32 31
From 1-5 years 109 113
After 5 years 98 121
Total 239 265

Consolidated financial statements • Annual report 2020 • ALK 80

Notes to the consolidated financial statements

25 Financial risks and financial instruments

Financial risk management policy

ALK-Abelló A/S manages the ALK Group’s financial risks centrally and coordinates the ALK Group’s cash management, including the raising of capital and investment of excess cash. The ALK Group complies with a policy, approved by the Board of Directors, to maintain a low risk profile, ensuring that the ALK Group is only exposed to foreign exchange rate risk, liquidity risk, interest rate risk, and credit risk in connection with its commercial activities. The ALK Group is exposed to exchange rate risks when intercompany balances and net assets of foreign subsidiaries are translated into DKK. In accordance with the ALK Group’s accounting policies, such currency translation adjustments are recognised in the income statement and in other comprehensive income, respectively.

The general objective of the ALK Group’s foreign exchange risk management is to limit and delay any adverse impact of exchange rate fluctuations on earnings and cash flows and thus increase the predictability of the financial results. The most significant financial risk relates to exchange rate fluctuations. The greatest exposure is to USD and in 2020, 15% (2019: 19%) of the revenue was denominated in USD. The sales are not deemed to be exposed to EUR due to Denmark’s participation in the European Exchange Rate Mechanism. As a result of operations, investments and financing, the ALK Group is exposed to exchange and interest rate changes.

Capital structure

The ALK Group manages its capital to ensure that all entities will be able to continue as going concern while maximising the return to stakeholders through the optimisation of the debt and equity balances. The capital structure of the ALK Group consists of net debt and equity. The dividend policy of the ALK Group is to distribute maximum possible dividend to ALK-Abelló A/S. The ALK Group has no open exchange rate hedge contracts at 31 December 2020 or 31 December 2019. The ALK Group’s Risk Committee reviews the capital structure annually. As a part of this review, the committee considers the cost of capital and the risks associated with each class of capital.

Foreign exchange rate risk

Foreign exchange rate risk arises due to imbalances between revenue and expenses in each individual currency. Foreign exchange rate exposure relating to future transactions and assets and liabilities is evaluated and hedged through matching of payments received and paid in the same currency. This serves to limit the impact on the financial results of any exchange rate fluctuations. The exchange rate exposure relating to net investments in foreign subsidiaries is not hedged by forward exchange contracts. The ALK Group hedges significant exchange rate exposures regarding future sales and purchase of goods in the coming six months in accordance with the ALK Group’s policy.

Sensitivity to a 10% increase in USD exchange rate

The table below shows the estimated effect of a 10% increase in the USD exchange rate on revenue, EBITDA and equity levels, respectively. In the sensitivity analysis, data for revenue and EBITDA are based on current short-term expectations and data for equity are based on actual equity at 31 December 2020. A decrease in the exchange rates will have a corresponding adverse effect.

Amounts in DKKm 31 December 2020 31 December 2019
USD
Revenue approx.+60 approx.+90
EBITDA approx.+75 approx.+95
Equity approx. 0 approx. 0

Consolidated financial statements • Annual report 2020 • ALK 81

Notes to the consolidated financial statements

25 Financial risks and financial instruments – continued

Net positions

Amounts in DKKm 31 December 2020 31 December 2019
Liquidity exposure DKK USD
Cash 18 65
Receivables 150 5
Liabilities (936) (144)
Total (768) (74)

Liquidity risk

In connection with the ALK Group’s ongoing financing of operations, including refinancing, efforts are made to ensure adequate and flexible liquidity. This is guaranteed by placing free funds in credit- worthy, liquid, interest bearing instruments of relatively short durations in accordance with the ALK Group’s policy. The liquidity risk is considered to be minimal due to the ALK Group’s current capital structure.

Amounts in DKKm Total cash flow* Within 1 year From 1-5 years After 5 years Total
31 December 2020
Mortgage debt and bank loans 704 74 29 535 1,042
Trade payables 746 74 74 546 740
Other financial liabilities** 1,140 1,171 939 661 2,771
Financial liabilities 2,590 1,319 1,042 1,742 4,553
31 December 2019
Mortgage debt and bank loans 725 81 29 577 1,412
Trade payables 777 81 81 546 1,485
Other financial liabilities** 1,045 1,085 820 677 2,582
Financial liabilities 2,547 1,247 930 1,800 5,479
  • Total cash flow includes interests.
    ** Other financial liabilities include lease liabilities of DKK 239 million (2019: DKK 265 million).

Consolidated financial statements • Annual report 2020 • ALK 82

Notes to the consolidated financial statements

25 Financial risks and financial instruments – continued

Interest rate risk

The ALK Group does not hedge its interest rate exposure, as this is not considered to be financially viable.

Credit risk

The ALK Group’s primary credit exposure is related to trade receivables and cash. The ALK Group has no major exposure relating to one single customer or business partner.According to the ALK Group’s policy for assuming credit exposure, all customers and business partners are credit rated regularly. Trade receivables are monitored at the local level and are distributed across a number of markets and customers. Therefore, the credit risk is considered to be low. For more information, see note 16. Concerning the ALK Group’s financial assets and financial liabilities, the earlier of the contractual revaluation and redemption date is applied. Effective interest rates are stated on the basis of the current level of interest rates on the balance sheet date.

Embedded derivative financial instruments

The ALK Group has made a systematic review of contracts that might contain terms that would make the contract or parts thereof a derivative financial instrument. The review did not lead to recognition of derivative financial instruments relating to the contracts.

Interest rate exposure

Amounts in DKKm Currency Expiry date 31 December 2020 31 December 2019
Cash Various 298 316
Interestbearing assets 298 316
Mortgage debt DKK 2035 258 277
Lease liabilities Various 2021-2033 239 265
Bank loans EUR 2022 446 448
Interestbearing liabilities 943 990
Carrying amount 1,241 1,306
Fixed/ floating interest rate
Cash Floating (1.40)-(0.05) (0.91)-1.32
Mortgage debt Floating 0.2 1.2
Lease liabilities Fixed 2.0 2.0
Bank loans Fixed 1.8 1.8

An increase in the interest rate of 1 percentage point on mortgage debt and bank loans would decrease net profit and equity by approximately DKK 5 million (2019: decrease of DKK 6 million).

An increase in the interest of 1 percentage point on cash would increase net profit and equity by approximately DKK 3 million (2019: increase of DKK 3 million).

Consolidated financial statements • Annual report 2020 • ALK 83
Notes to the consolidated financial statements

25 Financial risks and financial instruments – continued

26 Fees to the ALK Group’s auditors

Amounts in DKKm 2020 2019
Audit services 3 1
Other opinions - 2
Tax advisory services 3 3
Other services - -
Total 6 6

* In 2020, PricewaterhouseCoopers was appointed as the Group auditor at the annual general meeting (2019: Deloitte).

The fee for non-audit services provided by PricewaterhouseCoopers Statsautoriseret Revisionspartnerselskab (Denmark) of DKK 0.4 million relates to tax advisory and other general financial accounting matters.

In 2019, the fee for non-audit services provided by Deloitte Statsautoriseret Revisionspartnerselskab (Denmark) amounted to DKK 6.7 million. This included fees for consultancy services related to optimisation projects for the amount of DKK 5 million, which was preapproved by the Audit Committee. The remaining amount related to review of tax returns, review of other tax related matters, and other general financial accounting matters.

For information on ALK entities intended to be exempt from local audits of the 2020 accounts, see note 30.

Categories of financial instruments

Amounts in DKKm 2020 2019
Financial assets
Financial assets measured at amortised cost
Receivables from group companies 20 116
Trade receivables 544 407
Other receivables 96 133
Cash 298 316
Prepayments 265 211
Total 1,223 1,183
Financial liabilities
Financial liabilities measured at amortised cost
Mortgage debt 258 277
Bank loans 446 448
Lease liabilities 239 265
Trade payables 74 81
Other payables 880 760
Total 1,897 1,831

Measurement and fair value hierarchy

All financial assets and liabilities are measured at cost or amortised cost. The carrying amounts for these approximate fair value. There are no financial derivatives used in 2020 or 2019.

Consolidated financial statements • Annual report 2020 • ALK 84
Notes to the consolidated financial statements

27 Related parties

Related party exercising control

ALK-Abelló A/S is controlled by the Lundbeck Foundation (Lundbeckfond Invest A/S) domiciled in Copenhagen, Denmark, which holds 67.2% of the total number of votes in ALK Abelló A/S. The remaining shares are widely held. ALK-Abelló A/S is parent company, and ultimate parent for the ALK Group is the Lundbeck Foundation (Lundbeckfond Invest A/S, incorporated in Denmark).

Other related parties

Other related parties comprise ALK’s Board of Management and Board of Directors, companies in which the majority shareholder exercises control, and such companies’ subsidiaries, in this case H. Lundbeck A/S and Falck A/S and their subsidiaries.

Transactions and balances

Transactions and balances with the parent company’s majority shareholder:

  • ALK-Abelló A/S received DKK 121 million (2019: DKK 18 million) concerning outstanding company tax from the Lundbeck Foundation (Lundbeckfond Invest A/S). The company tax relates to ALK- Abelló A/S, ALK-Abelló Nordic A/S, and ALK e-com A/S.
  • Receivables from group companies to ALK-Abelló A/S relate to outstanding company tax of DKK 20 million (2019: DKK 116 million) covering ALK-Abelló A/S, ALK-Abelló Nordic A/S, and ALK e-com A/S.

Transactions with key management personnel consist of remuneration and exercise of share options, see notes 4 and 5 of the consolidated financial statements. No other transactions have taken place during the year with Board of Directors, Board of Management, major shareholders or other related parties.

Consolidated financial statements • Annual report 2020 • ALK 85
Notes to the consolidated financial statements

28 Events after the reporting period

No events have occured after the reporting period, that influence the evaluation of the consolidated financial statements.

29 Approval of financial statements

The financial statements were approved by the Board of Directors and authorised for issue on 10 February 2021.

30 List of companies in the ALK Group 31 December 2020 (wholly owned unless otherwise stated).

Nominal capital in 1,000 Denmark France Spain China
ALK-Abelló A/S (parent) CVR no. 63 71 79 16 Horsholm DKK 111,412 ALK-Abelló S.A. Varennes-en-Argonne EUR 160 ALK-Abelló S.A. Madrid EUR 4,671 ALK-Abelló A/S (branch) Hong Kong
DKK 1,000 EUR 1,790 EUR 2,000 ALK (Shanghai) Medical Technology Company Limited Shanghai CNY 500
DKK 500
ALK-Abelló Nordic A/S CVR no. 31 50 12 96 Horsholm
ALK e-com A/S CVR no. 39 26 68 81 Horsholm

Wholly owned by ALK-Abelló S.A.

Germany Italy Slovakia Austria Poland
ALK-Abelló Arzneimittel GmbH Hamburg ALK-Abelló S.p.A. Milan ALK Slovakia s.r.o. Bratislava EUR 5 ALK-Abelló Allergie-Service GmbH Linz ALK-Abelló Sp. z o.o. Krakow PLN 325
Wholly owned by ALK-Abelló S.A.
ALK Slovakia s.r.o. – od šteˇpny´ zavod (branch) Prague
Sweden Czech Republic Switzerland USA Norway
ALK-Abelló Nordic A/S (branch) Kungsbacka ALK-Abelló AG Volketswil CHF 100 ALK-Abelló, Inc. Austin, Texas USD 50 ALK-Abelló Nordic A/S (branch) Oslo
ALK AG Volketswil In Liquidation CHF 1,000 USD 329
USD 1
ALK-Abelló, Source Materials, Inc. Spring Mills, Pennsylvania
OKC Allergy Supplies Inc. Oklahoma City, Oklahoma
Wholly owned by ALK-Abelló Inc.
Turkey United Kingdom Netherlands Canada
ALK-Abelló Nordic A/S (branch) Helsinki ALK-Abelló Ltd. VAT Reg no. GB724461445 Reading Exemption for local audit of the 2020 accounts according to the requirements of the UK Companies Act is intended. GBP 1 ALK-Abelló B.V. Btw-nr. NL005302766B01 Nieuwegein Exemption for local audit of the 2020 accounts under the ruling of the Article 2:403 of the Dutch Civil Code is intended. ALK-Abelló Pharmaceuticals, Inc. Mississauga, Ontario CAD 3,000
ALK ilaç ve Alerji Ürünleri Ticaret Anonim S¸irketi Istanbul TRY 5,150 EUR 23
OKC Crystal Laboratory Inc. Luther, Oklahoma USD 1
Wholly owned by ALK-Abelló,Source Materials, Inc.

Consolidated financial statements • Annual report 2020 • ALK 86
Definitions

31 Alternative Performance Measures

Term Definitions
Gross margin – % Gross profit x 100 / Revenue
EBITDA margin – % EBITDA x 100 / Revenue
Net asset value per share Net asset value / Number of shares end of period
Invested capital Intangible assets, tangible assets, inventories and current receivables reduced by liabilities except for mortgage debt and bank loans
EBITDA reconciliation to net profit / (loss) Net profit / (loss) for the year + Tax + Financial income - Financial expenses + Depreciation, amortisation and impairment
Return on equity (ROE) – % Net profit/(loss) for the period x 100 / Average equity
Pay-out ratio – % Proposed dividend x 100 / Net profit/(loss) for the year
Earnings/(loss) per share (EPS) Net profit/(loss) for the period / Average number of outstanding shares
Earnings/(loss) per share diluted (DEPS) Net profit/(loss) for the period / Average number of outstanding shares diluted
Cash flow per share (CFPS) Cash flow from operating activities / Average number of outstanding shares
ROIC incl. goodwill – % Operating profit x 100 / Average invested capital incl. goodwill
Price earnings ratio (PE) Markets
Amounts in DKKm 2020 2019
Net asset value 3,153 3,176
Equity 3,153 3,176
Intangible assets 624 544
Tangible assets 1,704 682
Inventories 1,093 1,739
Trade receivables 544 1,056
Receivables from group companies 20 407
Income tax receivables 116 9
Other receivables 96 24
Cash 298 9
Prepayments 265 211
Invested capital 3,153 3,176
EBITDA 255 241
Net profit / (loss) for the year 25 (50)
Tax -19 39
Financial income -5 (22)
Financial expenses 54 245
Depreciation, amortisation and impairment 255 241
## Annual report 2020 • ALK 87
### Contents of the parent company financial statements
Parent company financial statements
Notes
Income statement
Balance sheet
Accounting policies
Revenue and segment information
Staff costs
Statement of changes in equity
Special items
Financial income and expenses
Tax on profit/(loss) for the year
Intangible assets
Property, plant and equipment
Deferred tax
Investments in subsidiaries
Inventories
Mortgage debt and bank loans
Pensions and similar liabilities
Lease liabilities
Tax payables to group companies
Contingent liabilities and commitments
Related parties
Fees to ALK-Abelló A/S’ auditors
Proposed appropriation of net profit/(loss)
Events after the reporting period

Parent company financial statements • Annual report 2020 • ALK 88

Income statement

Amounts in DKKm Note 2020 2019
Revenue 2 2,015 1,011
Cost of sales 3,4 1,004 856
Gross profit 1,011 155
Research and development expenses 3 747 109
Sales and marketing expenses 3 508 195
Administrative expenses 3 195 117
Other operating items, net 3,4 (2) (3,18)
Operating profit/(loss) (EBIT) 198 (642)
Income from investments in subsidiaries 10 831 773
Financial income 5 14 80
Financial expenses 5 49 33
Profit/(loss) before tax (EBT) 994 178
Tax on profit/(loss) 6 105 (129)
Net profit/(loss) 889 307

Parent company financial statements • Annual report 2020 • ALK 89

Balance sheet

Amounts in DKKm Note 31 Dec. 2020 31 Dec. 2019 Amounts in DKKm Note 31 Dec. 2020 31 Dec. 2019
Assets Equity and liabilities
Non-current assets Equity
Intangible assets 7 119 137 Share capital 4 111 111
Capitalised development costs 119 137 Retained earnings 5 2,771 1,822
Tangible assets 8 324 263 Total equity 2,886 1,938
Land and buildings 35 346
Plant and machinery 158 22 Liabilities
Other fixtures and equipment 151 773 Mortgage debt 12 240 259
Property, plant and equipment in progress 186 712 Bank loans 13 446 448
Investments in subsidiaries 10 1,062 1,058 Pensions and similar liabilities 14 57 19
Receivables from group companies 9 975 964 Lease liabilities 15 18 21
Other non-current assets 121 111 Tax payables to group companies 16 151 186
Deferred tax assets 326 356 Other non-current liabilities 31 18
Income tax receivables 109 133 Total non-current liabilities 1,074 1,073
Total non-current assets 3,414 3,170 Current liabilities
Current assets Trade payables 841 8
Inventories 11 361 418 Payables to group companies 1,225 9
Trade receivables 770 71 Lease liabilities 332 318
Receivables from group companies 419 113 Other payables 1,230 1,591
Other receivables 180 233 Total current liabilities 3,628 2,939
Prepayments 1,135 1,515 Total liabilities 4,702 4,012
Cash 162 188
Total cash 162 188
Total current assets 1,677 1,323
Total assets 5,091 4,493 Total equity and liabilities 5,091 4,493

Parent company financial statements • Annual report 2020 • ALK 90

Statement of changes in equity

Amounts in DKKm Share capital Reserve for capitalised development costs Retained earnings Proposed dividend Total equity
Equity at 1 January 2020 111 1,822 889 29 1,938
Appropriated from net profit - - 889 - 889
Share-based payments - - 29 - 29
Share options settled - - - (24) (24)
Sale of treasury shares - - 11 - 11
Transfer to/(from) legal reserves - 1 (1) - -
Tax related to items recognised directly in equity - 43 - - 43
Other transactions - 949 - - 949
Equity at 31 December 2020 111 2,771 4 - 2,886

See note 17 in the consolidated financial statements for information on treasury shares.

Parent company financial statements • Annual report 2020 • ALK 91

Notes to the parent company financial statements

1 Accounting policies

General
The financial statements of the parent company ALK-Abelló A/S for the period 1 January – 31 December 2020 have been prepared in accordance with the Danish Financial Statements Act for large reporting class D enterprises.

The financial statements are presented in Danish kroner (DKK), which is also the functional currency of the company.

Changes in accounting policies
The accounting policies are unchanged from last year.

Accounting policies
The accounting policies are as described below.
Differences relative to the ALK Group’s accounting policies
The parent company’s accounting policies for recognition and measurement are in accordance with the ALK Group’s accounting policies with the following exceptions:

Balance sheet
Investments in subsidiaries
Investments in subsidiaries are measured at cost. Where the recoverable amount of the investments is lower than cost, the investments are written down to this lower value. In addition, cost is written down to the extent that dividends distributed exceed the accumulated earnings in the company since the acquisition date. In the event of indications of impairment, an impairment test is performed of investments in subsidiaries.

Income statement
Results of investments in subsidiaries
Dividends from investments in subsidiaries are recognised in the parent company’s financial statements when the right to the dividend finally vests, typically at the date of the company’s approval in general meeting of the dividend of the company in question less any write-downs at the investments.

Other accounting information
Acquisition of activities from subsidiaries
Acquisition of activities from subsidiaries is accounted for using the purchase method. On initial recognition, goodwill is measured and recognised as the excess of the consideration transferred exceeding the fair value of the net assets acquired at the acquisition date.
Cash flow statement
As allowed under section 86 (4) of the Danish Financial Statements Act, no cash flow statement is presented, as this is included in the consolidated cash flow statement.

Goodwill
Goodwill is measured at cost less accumulated amortisation and impairment. Amortisation is calculated using the straight-line method over the expected useful life, estimated at 10 years. This estimate was made on the basis of estimated useful lives of the assets acquired.

Capitalisation of development costs
A reserve for capitalisation of development costs less deferred tax is recognised in the statement of equity. The reserve contains development costs, less amortisation/impairment losses, and less deferred tax, capitalised since 1 January 2016.

Parent company financial statements • Annual report 2020 • ALK 92

Notes to the parent company financial statements

2 Revenue and segment information

Amounts in DKKm 2020 2019
Sale of goods 1,953 822
Royalties 58 34
Services 4 -
Total revenue 2,015 856

Geographical markets (based on customer location):
* Europe comprises the EU, UK, Norway and Switzerland
* North America comprises the USA and Canada
* International markets comprise Japan, China and all other countries

Amounts in DKKm Europe North America International markets Total revenue
2020 1,735 280 694 2,015
2019 856 162 856 856

3 Staff costs

Amounts in DKKm 2020 2019
Wages and salaries 609 578
Pensions 57 53
Other social security costs, etc. - -

4 Special items

Special items include impairment of DKK 24 million (2019: DKK 262 million) of which DKK 22 million is related to intangible assets (2019: DKK 0) and DKK 2 million is related to tangible assets (2019: DKK 30 million). In 2020, investments in subsidiaries were not impaired (2019: DKK 232 million).

The impairment of intangible assets includes DKK 13 million related to impairment of acquired intellectual property rights and DKK 9 million related to impairment of software projects in progress. In the income statement, the impairment of intangible assets is recognised with DKK 19 million in research and development expenses and DKK 3 million as cost of sales.

The impairment of tangible assets of DKK 2 million is related to impairment of production equipment in progress. In the income statement, the impairment of tangible assets is recognised as cost of sales.

In 2019, impairment of investments in subsidiaries of DKK 232 million decreased the income from investments in subsidiaries. The impairment was calculated as the result of assessment of recoverable amount of the subsidiaries. Based on the assessment, the investments in the following subsidiaries were impaired: ALK-Abelló Source Materials Inc., ALK e-com A/S, and ALK ilac ve Alerji Ürünleri Ticaret Anonim Sirketi.

The impairment of tangible assets of DKK 30 million was related to ALK’s divestment of its part-share of a formulation production line for tablets to production partner Catalent effective 30 June 2019. The impairment of tangible assets was recognised as cost of sales.

For the assets where ALK estimates that there is a recoverable amount, such amount was determined based on the fair value less cost to sell or the value in use of the respective asset.# Notes to the parent company financial statements

5 Financial income and expenses

Amounts in DKKm 2020 2019
Total financial income 14 26
Interest on receivables from group companies 10 26
Other interest income 4 0
Currency gain, net 0 0
Total financial expenses 33 24
Other interest expenses* 29 14
Currency loss, net 4 10
* In 2020, other interest expenses include net interest related to uncertain tax positions of DKK 7 million (2019: DKK 11 million was included in other interest income) and DKK 3 million related to lease interest expenses (2019: DKK 3 million).

6 Tax on profit/(loss) for the year

Amounts in DKKm 2020 2019
Profit/(loss) before tax 994 178
Income tax, tax rate of 22% 219 39
Non-taxable income (199) (179)
Non-deductible expenses 9 6
Prior year adjustments, income tax (114) (2)
Prior year adjustments, deferred tax 4 (1)
Other taxes and adjustments (18) 3
Change in valuation of net tax asset 3 (1)
Tax on profit/(loss) for the year 105 (129)

7 Intangible assets

Amounts in DKKm Goodwill and Assets in progress Patents, trademarks and rights Development cost* Software Total
Cost beginning of year 867 69 14 280 1,270
Additions 0 0 40 0 40
Disposals (1) (13) (9) (22) (45)
Transfer to/ from other groups 0 0 0 0 0
Cost year end 866 56 45 258 1,265
Amortisation and impairment beginning of year 867 67 1 190 1,125
Amortisation for the year 0 0 1 19 20
Amortisation on disposals (13) (9) (22) (27) (71)
Impairment for the year 0 0 0 0 0
Amortisation and impairment year end 854 58 0 182 1,074
Carrying amount year end 12 (2) 45 76 191
Amounts in DKKm Goodwill and Assets in progress Patents, trademarks and rights Development cost* Software Total
Cost beginning of year 820 873 855 836 3,384
Additions 0 16 26 0 42
Disposals (28) (14) (278) (6) (326)
Transfer to/ from other groups 0 0 0 0 0
Cost year end 792 875 603 830 3,100
Amortisation and impairment beginning of year 773 708 676 22 1,479
Amortisation for the year 20 22 26 1 69
Amortisation on disposals (18) (12) (9) (1) (40)
Impairment for the year 0 0 0 0 0
Amortisation and impairment year end 775 696 693 22 1,488
Carrying amount year end 17 179 (90) 808 1,612
  • The capitalised development cost relates to development of medical device products where the individual minor development projects are running for short-term periods and are subject to limited risk. The development projects are generating economic benefits in the form of sale of goods. At 31 December 2020, the capitalised development cost relates to the historical development of the adrenaline auto-injector Jext® for the European market.

8 Property, plant and equipment

Amounts in DKKm Land and buildings Plant and machinery Fixtures and equipment Assets in progress Total
Cost beginning of year 356 610 417 8 1,391
Additions 28 122 271 105 526
Disposals (4) (24) (5) (33) (66)
Transfer to/from other groups 0 0 0 0 0
Adjustment of receivables from group companies 0 0 0 0 0
Cost year end 380 708 683 180 1,951
Depreciation and impairment beginning of year 264 287 324 0 875
Depreciation for the year 6 7 8 0 21
Depreciation of disposals (2) (3) (6) 0 (11)
Impairment for the year 0 0 0 0 0
Depreciation and impairment year end 268 291 326 0 885
Carrying amount year end 112 417 357 180 1,066
Amounts in DKKm Land and buildings Plant and machinery Fixtures and equipment Assets in progress Total
Cost beginning of year 351 610 417 16 1,394
Additions 6 44 10 0 60
Disposals (1) (24) (5) (4) (34)
Transfer to/from other groups 0 0 0 0 0
Adjustment of receivables from group companies 0 0 0 0 0
Cost year end 356 630 422 12 1,420
Depreciation and impairment beginning of year 259 263 263 0 785
Depreciation for the year 8 26 15 0 49
Depreciation of disposals (1) (1) (2) 0 (4)
Impairment for the year 0 0 0 0 0
Depreciation and impairment year end 266 288 276 0 830
Carrying amount year end 90 342 146 12 590

of which assets held under leases | 0 | 0 | 10 | 0 | 10
of which assets held under leases
| 0 | 0 | 19 | 0 | 19

  • Land and buildings in Denmark include buildings on land leased from Scion DTU A/S, Hørsholm. The leases are open-ended and the estimated lease terms are 15 years.

9 Deferred tax

Amounts in DKKm Current and other assets Tax losses carried forward Intangible assets Tangible assets Liabilities Total
Carrying amount beginning of year 17 31 351 356 655 1,326
Recognised in the income statement, net (61) (79) (19) (6) 8 (157)
Recognised in equity, net (share-based payments) 8 43 35 8 0 94
Carrying amount year end (36) 95 367 358 663 1,467
Amounts in DKKm Current and other assets Tax losses carried forward Intangible assets Tangible assets Liabilities Total
Carrying amount beginning of year 31 17 351 356 655 1,310
Adjustment of receivables from group companies 0 0 0 0 0 0
Carrying amount year end 31 17 351 356 655 1,310

Impact from initial application of IFRIC 23 | (57) | (33) | 4 | (57) | (57)
Adjustment to prior years | 0 | 0 | 0 | 0 | 0 | 0
Adjustment of receivables from group companies | 0 | 0 | 0 | 0 | 0 | 0
Carrying amount year end | (26) | (16) | 355 | 300 | 598 | 1,251

Recognised in the income statement, net | (29) | 10 | (6) | (19) | (29)
Recognised in equity, net (share-based payments) | 22 | 5 | 8 | 22 | 27
Carrying amount year end | (7) | 15 | 363 | 322 | 654 | 1,347

Value of land and buildings subject to mortgages | 0 | 0 | 0 | 0 | 0 | 0
Value of land and buildings subject to mortgages | 0 | 0 | 0 | 0 | 0 | 0

ALK-Abelló A/S is included in a joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S) and its Danish subsidiaries. ALK-Abelló A/S recognises deferred tax assets including the tax value of tax losses if it is probable that it can be utilised against future taxable income within a foreseeable future (5 years). This includes an assessment of the possibilities to utilise tax losses in the joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S).

10 Investments in subsidiaries

Amounts in DKKm 2020 2019
Cost beginning of year 1,466 905
Capital contribution in subsidiaries during the year 4 561
Cost year end 1,470 1,466
Write-down beginning of year 408 176
Write-down during the year, cf. note 4 0 232
Write-down year end 408 408
Carrying amount year end 1,062 1,058

In the income statement, income from investments in subsidiaries is dividends, which amounts to DKK 831 million (2019: DKK 1,005 million) less write-down of investments in subsidiaries which amounts to DKK 0 (2019: DKK 232 million).

For an overview of all subsidiaries see note 30 in the consolidated financial statements.

11 Inventories

Amounts in DKKm 2020 2019
Raw materials 75 31
Work in progress 255 87
Manufactured goods and goods for resale 31 307
Total 361 425
Amount of write-down of inventories during the year 4 3
Amount of reversal of write-down of inventories during the year 1 8

12 Mortgage debt and bank loans

Amounts in DKKm 2020 2019
Debt to mortgage credit institutions secured by real property 18 18
Mortgage debt is due as follows:
Within 1 year 0 0
From 1-5 years 18 18
After 5 years 0 0
Total 18 18
Bank loans 408 446
Bank loans are due as follows:
Within 1 year 176 258
From 1-5 years 232 188
After 5 years 0 0
Total 408 446

13 Pensions and similar liabilities

Amounts in DKKm 2020 2019
Pensions and similar liabilities expire as follows:*
Within 1 year 1 1
From 1-5 years 2 0
After 5 years 0 0
Total 3 1
  • Pensions and similiar liabilities relate to the provision for transition period for the Danish Holiday Act.

14 Lease liabilities

Amounts in DKKm 2020 2019
Lease liabilities expire as follows:
Within 1 year 8 9
From 1-5 years 35 34
After 5 years 95 95
Total 138 138

15 Tax payables to group companies

Non-current tax payables to group companies of DKK 111 million (2019: DKK 109 million) is expected to expire after 1 to 5 years.

16 Contingent liabilities and commitments

  • In December 2020, ALK-Abelló A/S issued a hold-harmless letter to ALK-Abelló Arzneimittel GmbH regarding costs under ongoing tax audits in Germany (unlimited guarantee). The letter replaces the letter issued in April 2019.
  • In January 2021, ALK-Abelló A/S issued a letter of financial support to ALK e-com A/S. The policy continues for a period of at least 12 months from the date of approval of the 31 December 2020 financial statements.
  • Provisions recognised as debt to affiliates have been made to cover such exposures and the mentioned possible uncertainties are in addition to what is already provided for.

For more information on contingent liabilities and commitments, see note 23 in the consolidated financial statements.

17 Related parties

ALK-Abelló A/S is included in the consolidated financial statements of the Lundbeck Foundation (Lundbeckfond Invest A/S, incorporated in Denmark).

ALK-Abelló A/S has had transactions with subsidiaries during 2020. All subsidiaries are owned 100%. The transactions are eliminated in the consolidated financial statements. Transactions with the majority shareholder are disclosed in note 27 in the consolidated financial statements. Apart from remuneration, no other transactions have taken place during the year with Board of Directors, Board of Management, major shareholders or other related parties.

Remuneration etc. to Board of Directors and Board of Management

For information on remuneration and exercise of share options for the ALK Group’s Board of Directors and Board of Management, see note 4 and 5 in the consolidated financial statements.

18 Fees to ALK-Abelló A/S’ auditors

Amounts in DKKm 2020 2019
Audit services 2 2
Tax advisory services 0 1
Other services 2 5
Total 4 8
  • In 2020, PricewaterhouseCoopers was appointed as the Group auditor at the annual general meeting (2019: Deloitte). In 2019, other services included fees for consultancy services related to optimisation projects for the amount of DKK 5 million, which was preapproved by the Audit Committee. The remaining amount was related to various deliveries including compliance and advisory services.

19 Proposed appropriation of net profit/(loss)

Amounts in DKKm 2020 2019
Proposed dividend 889 307
Retained earnings 0 0
Total 889 307

20 Events after the reporting period

No events have occurred after the reporting period that influence the evaluation of the parent company financial statements.# Management’s review

Annual report 2020

ALK 97

Financial highlights and key ratios by quarter for the ALK Group* (unaudited)

Q4 2020 (unaudited) Q3 2020 (unaudited) Q2 2020 (unaudited) Q1 2020 (unaudited) Q4 2019 (unaudited) Q3 2019 (unaudited) Q2 2019 (unaudited) Q1 2019 (unaudited)
Amounts in DKKm
Income statement
Revenue 3,491 1,463 515 991 412 178 338 72
Cost of sales 772 344 121 252 48 772 336 103
Research and development expenses 254 63 956 371 113 281 54 5,563
Sales and marketing expenses 2,664 3,153 5,563 2,664 3,153 5,573 2,827 3,203
Administrative expenses 5,683 2,748 3,243 5,639 2,814 3,279
Other operating items, net
Operating profit/(loss) (EBIT) 1,125 237
Net financial items
Profit/(loss) before tax (EBT) (26) (196) (15) (59) (7) (39) - (4)
Net profit/(loss) (45) (10) 75 (53)
Balance sheet
Total assets 5,563 2,664 3,153 5,563 2,664 3,153 5,573 2,827
Invested capital 3,203 5,683 2,748 3,243 5,639 2,814 3,279
Equity 237
Cash flow and investments
Depreciation, amortisation and impairment 245 301 73 195 (72) 52 59 84
Cash flow from operating activities 61 70 150 (49) 101 25 (9) 6
Cash flow from investing activities (1) (1) - - 245 (78) (49)
EBITDA 395 198
Free cash flow 56 123 (94) 6 21
Information on shares
Share capital (Shares in thousands of DKK 10 each) 11,141 11,141 11,141 11,141 11,141 11,141 11,141 11,141
Share price, end period – DKK 2,500 283 11,141 2,500 283 11,141 2,098 287
Net asset value per share – DKK 11,141 1,771 291 11,141 1,542 294

Revenue by region and product group

Q4 2020 (unaudited) % change Q3 2020 (unaudited) % change Q2 2020 (unaudited) % change Q1 2020 (unaudited) % change Q4 2019 (unaudited) % change Q3 2019 (unaudited) % change Q2 2019 (unaudited) % change Q1 2019 (unaudited) % change
Europe
– SCIT/SLIT-drops 2,550 (8) 1,320 (-9) 1,019 (40) 211 (18) 734 (17) 391 (-2) 301 (54) 42 (18)
– SLIT-tablets 556 (6) 280 (-18) 211 (56) 65 (35) 540 (-2) 258 (-15) 236 (22) 46 (-11)
– Other products and services 213 (19) 720 (11) 391 (-3) 271 (33) 58 (36)
North America
– SCIT/SLIT-drops 573 (-10) 275 (-5) 85 (4) 155 (-2) 75 (-1) 22 (37) 58 (13) 138 (-14)
– SLIT-tablets 53 (-24) 130 (-19) 68 (-3) 17 (-19) 53 (-24) 130 (-19)
– Other products and services 150 (-4) 74 (7) 26 (22) 50 (-24) 52 (-16) 150 (-4) 74 (7) 26 (22)
International markets
– SCIT/SLIT-drops 368 (58) 78 (41) 266 (74) 24 (-2) 102 (46) 11 (-17) 86 (65) 78 (110)
– SLIT-tablets 19 (525) 53 (90) 102 (56) 26 (53) 53 (90) 102 (56) 26 (53) 68 (64)
– Other products and services 5 (23) 6 (-1) 8 (12)
Total revenue 3,491 (8) 1,673 (-7) 1,370 (42) 448 (-4) 991 (16) 477 (-2) 409 (55) 105 (-1)

Key figures

Q4 2020 (unaudited) Q3 2020 (unaudited) Q2 2020 (unaudited) Q1 2020 (unaudited) Q4 2019 (unaudited) Q3 2019 (unaudited) Q2 2019 (unaudited) Q1 2019 (unaudited)
Gross margin – % 58 58 55 56 61 57 55 55
EBITDA margin – % 11 12 11 10 21 17 18 17
Earnings/(loss) per share (EPS) – DKK (2.9) (2.9) 17.9 8.8 (1.8) (1.8) (4.4) 7.3
Earnings/(loss) per share diluted (DEPS) – DKK (0.9) (0.9) 7.7 7.9 7.8 6.4 5.2
Cash flow per share (CFPS) – DKK
Share price/Net asset value
Average number of employees (FTE) 2,419 2,433 2,419 2,418 2,404

* Management’s review comprises this page as well as pages 1-46 and Financial highlights and key ratios for the ALK Group on page 13.

Definitions: see page 86.

ALK-Abelló A/S • Bøge Allé 6-8 • DK-2970 Hørsholm, Denmark • CVR no. 63 71 79 16 • Tel. +45 45 74 75 76 • www.alk.net

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