AGIOS PHARMACEUTICALS, INC. — Director's Dealing 2017

Aug 24, 2017

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: AGIOS PHARMACEUTICALS INC (AGIO)
CIK: 0001439222
Period of Report: 2017-08-22

Reporting Person: Cantley Lewis Clayton Jr. (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2017-08-22	Common stock	S	500	$56.63	Disposed	88894	Direct
2017-08-22	Common stock	S	500	$56.63	Disposed	88934	Indirect
2017-08-22	Common stock	S	500	$56.61	Disposed	88394	Direct
2017-08-22	Common stock	S	500	$56.61	Disposed	88434	Indirect
2017-08-23	Common stock	S	500	$57.09	Disposed	87894	Direct
2017-08-23	Common stock	S	500	$57.09	Disposed	87934	Indirect
2017-08-23	Common stock	S	500	$57.07	Disposed	87394	Direct
2017-08-23	Common stock	S	500	$57.07	Disposed	87434	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common stock	20803	Indirect
Common stock	20803	Indirect

Footnotes

F1: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $55.31 to $57.52. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3: This amount reflects 4,197 shares transferred from indirect to direct ownership from a grantor retained annuity trust distribution on July 28, 2017.

F4: This amount reflects 4,197 shares transferred from a grantor retained annuity trust distribution on July 28, 2017.

F5: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

F6: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $55.33 to $57.52. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F7: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $56.77 to $57.34. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F8: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $56.77 to $57.33. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F9: Shares held by grantor retained annuity trusts for the benefit of the reporting person and his two children, of which the reporting person is trustee and sole annuitant.

F10: Shares held by grantor retained annuity trusts for the benefit of the reporting person's spouse and their two children, of which the reporting person's spouse is trustee and sole annuitant.