AGIOS PHARMACEUTICALS, INC. — Director's Dealing 2017

Dec 8, 2017

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: AGIOS PHARMACEUTICALS INC (AGIO)
CIK: 0001439222
Period of Report: 2017-12-06

Reporting Person: Cantley Lewis Clayton Jr. (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2017-12-06	Common stock	S	543	$57.90	Disposed	80851	Direct
2017-12-06	Common stock	S	542	$57.90	Disposed	80892	Indirect
2017-12-06	Common stock	S	253	$58.95	Disposed	80598	Direct
2017-12-06	Common stock	S	254	$58.95	Disposed	80638	Indirect
2017-12-06	Common stock	S	204	$60.01	Disposed	80394	Direct
2017-12-06	Common stock	S	204	$60.01	Disposed	80434	Indirect
2017-12-07	Common stock	S	288	$59.68	Disposed	80106	Direct
2017-12-07	Common stock	S	288	$59.68	Disposed	80146	Indirect
2017-12-07	Common stock	S	631	$60.45	Disposed	79475	Direct
2017-12-07	Common stock	S	631	$60.45	Disposed	79515	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common stock	20803	Indirect
Common stock	20803	Indirect

Footnotes

F1: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $57.48 to $58.30. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F3: Shares held by Vicki Lee Sato, who is the reporting person's spouse.

F4: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $58.58 to $59.21. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F5: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $59.62 to $60.55. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F6: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $58.99 to $59.95. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F7: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $60.00 to $60.79. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

F8: Shares held by grantor retained annuity trusts for the benefit of the reporting person and his two children, of which the reporting person is trustee and sole annuitant.

F9: Shares held by grantor retained annuity trusts for the benefit of the reporting person's spouse and their two children, of which the reporting person's spouse is trustee and sole annuitant.