AGIOS PHARMACEUTICALS, INC. — Director's Dealing 2015

Feb 19, 2015

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: AGIOS PHARMACEUTICALS INC (AGIO)
CIK: 0001439222
Period of Report: 2015-02-19

Reporting Person: THIRD ROCK VENTURES LP (10% Owner)
Reporting Person: Third Rock Ventures GP, L.P. (10% Owner)
Reporting Person: TRV GP, LLC (10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2015-02-19	Common Stock	J	3070090	—	Disposed	0	Direct
2015-02-19	Common Stock	J	760195	—	Acquired	760195	Direct
2015-02-19	Common Stock	J	760195	—	Disposed	0	Direct

Footnotes

F1: Distribution of shares in kind by Third Rock Ventures, L.P. ("TRV") on a pro rata basis to its partners.

F2: The shares are directly held by TRV. The general partner of TRV is Third Rock Ventures GP, L.P. ("TRV GP"). The general partner of TRV GP is TRV GP, LLC ("TRV GP LLC") and , as such, each of TRV GP and TRV GP LLC exercises shared voting and investment power over the shares hold of record by TRV. Each Reporting Person disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any.

F3: TRV GP received shares distributed in kind by TRV on a pro rata basis to its partners.

F4: The shares are directly held by TRV GP. As such, TRV GP LLC exercises voting and investment power over the shares held of record by TRV GP. Each of the Reporting Persons disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any.

F5: Distribution of shares in kind by TRV GP on a pro rata basis to its partners.