ADHERIUM LIMITED — Share Issue/Capital Change 2025

Nov 10, 2025

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

==> picture [21 x 22] intentionally omitted <==

Announcement Summary

Entity name

ADHERIUM LIMITED

Date of this announcement

Tuesday November 11, 2025

The +securities the subject of this notification are:

+Securities issued as part of a transaction or transactions previously announced to the market in an Appendix 3B that are not quoted, and are not intended to be quoted, on ASX

Total number of +securities to be issued/transferred

		Total number of
ASX +security		+securities to be
code	Security description	issued/transferred	Issue date
ADRAX	OPTION EXPIRING 15-NOV-2026 EX $0.005	140,000,000	07/11/2025
ADRAX	OPTION EXPIRING 15-NOV-2026 EX $0.005	348,767,707	10/11/2025
ADRAX	OPTION EXPIRING 15-NOV-2026 EX $0.005	5,733,334	11/11/2025

Refer to next page for full details of the announcement

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

1 / 6

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

==> picture [21 x 22] intentionally omitted <==

Part 1 - Entity and announcement details

1.1 Name of entity

ADHERIUM LIMITED

We (the entity named above) give notice of the issue, conversion or payment up of the following unquoted +securities.

1.2 Registered number type Registration number ACN 605352510

1.3 ASX issuer code

ADR

1.4 The announcement is

New announcement

1.5 Date of this announcement

11/11/2025

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

2 / 6

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

==> picture [21 x 22] intentionally omitted <==

Part 2 - Issue details

2.1 The +securities the subject of this notification are:

+Securities issued as part of a transaction or transactions previously announced to the market in an Appendix 3B that are not quoted, and are not intended to be quoted, on ASX

Previous Appendix 3B details:

Announcement Date and Announcement Title Selected Appendix 3B to submit quotation Time request 01-Jul-2025 12:19 Update - Update - Proposed issue of An accelerated offer (early retail) securities - ADR

2.3a.2 Are there any further issues of +securities yet to take place to complete the transaction(s) referred to in the Appendix 3B?

Yes

2.3a.3 Please provide details of the further issues of +securities yet to take place to complete the transaction(s) referred to in the Appendix 3B

Issue of Bonus Options upon conversion of options under the ANREO Offer before 15 November 2025

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

3 / 6

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

==> picture [21 x 22] intentionally omitted <==

Part 3A - number and type of +securities the subject of this notification (existing class or new class) where issue has previously been notified to ASX in an Appendix 3B

Early Retail Securities

ASX +security code and description ADRAX : OPTION EXPIRING 15-NOV-2026 EX $0.005 Date the +securities the subject of this notification were issued 7/11/2025 Any other information the entity wishes to provide about the +securities the subject of this notification Issue details Number of +securities 140,000,000 Were the +securities issued for a cash consideration? No Please describe the consideration being provided for the +securities Issue of Bonus Options upon conversion of options under the ANREO Offer before 15 November 2025

ASX +security code and description ADRAX : OPTION EXPIRING 15-NOV-2026 EX $0.005 Date the +securities the subject of this notification were issued 10/11/2025 Any other information the entity wishes to provide about the +securities the subject of this notification

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

4 / 6

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

==> picture [21 x 22] intentionally omitted <==

Issue details

Number of +securities

348,767,707

Were the +securities issued for a cash consideration? No

Please describe the consideration being provided for the +securities

Issue of Bonus Options upon conversion of options under the ANREO Offer before 15 November 2025

ASX +security code and description

ADRAX : OPTION EXPIRING 15-NOV-2026 EX $0.005

Date the +securities the subject of this notification were issued

11/11/2025

Any other information the entity wishes to provide about the +securities the subject of this notification

Issue details

Number of +securities

5,733,334

Were the +securities issued for a cash consideration? No

Please describe the consideration being provided for the +securities

Issue of Bonus Options upon conversion of options under the ANREO Offer before 15 November 2025

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

5 / 6

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

==> picture [21 x 22] intentionally omitted <==

Part 4 - +Securities on issue

Following the issue, conversion or payment up of the +securities the subject of this notification, the +securities of the entity will comprise:

The figures in parts 4.1 and 4.2 below are automatically generated and may not reflect the entity's current issued capital if other Appendix 2A, Appendix 3G or Appendix 3H forms are currently with ASX for processing.

4.1 Quoted +securities (Total number of each +class of +securities issued and quoted on ASX)

	Total number of
ASX +security code and description	+securities on issue
ADR : ORDINARY FULLY PAID	1,926,845,635

4.2 Unquoted +securities (Total number of each +class of +securities issued but not quoted on ASX)

	Total number of
ASX +security code and description	+securities on issue
ADRAW : OPTION EXPIRING 31-JUL-2026 EX $0.005	901,007,772
ADRAD : OPTION EXPIRING VARIOUS DATES EX VARIOUS PRICES	10,565,540
ADRAS : CONVERTIBLE NOTES	76,543,650
ADRAX : OPTION EXPIRING 15-NOV-2026 EX $0.005	558,180,432
ADRAP : STOCK APPRECIATION RIGHTS	24,656,522

Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities

6 / 6