ADHERIUM LIMITED — Share Issue/Capital Change 2017

Aug 10, 2017

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11 August 2017

ASX: ADR

ABN

ASX Market Announcements ASX Limited Level 4, North Tower, Rialto 525 Collins Street Melbourne VIC 3000

RE: ADHERIUM LIMITED - RELEASE OF SECURITIES FROM ESCROW

In connection with the quotation of Adherium Limited’s fully paid ordinary shares (Shares) on the Australian Securities Exchange ( ASX ) on 26 August 2015 certain security holders in the Company were required to enter into ASX restriction agreements. These agreements restricted the relevant security holders from dealing in their securities for periods of up to 24 months from the date of quotation.

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Company Overview

Adherium is a global leader in digital health technologies which address sub optimal medication use in chronic disease.

Directors

Mr Thomas Lynch (Chair) Mr Garth Sutherland (Founder) Mr Jeremy Curnock Cook Dr William Hunter Mr Bruce McHarrie Prof John Mills Mr Bryan Mogridge

Chief Executive

Arik Anderson

In accordance with ASX Listing Rule 3.10A, Adherium advises that 35,494,024 fully paid ordinary shares of the Company will be released from mandatory ASX restriction on 26 August 2017.

Joint Company Secretaries

Mr Rob Turnbull Mr Mark Licciardo

Registered Office

Application for quotation of these fully paid ordinary shares will also be made following their release from restriction.

Yours faithfully

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Rob Turnbull

Collins Square, Tower 4 Level 18, 727 Collins Street Melbourne, VIC 3000, Australia +61 3 8657 5540

NZ Office

Level 2, 204 Quay Street Auckland 1010 New Zealand

Investor Relations

investors@adherium.com

CFO & Joint Company Secretary

Websites

www.adherium.com www.smartinhaler.com