ADHERIUM LIMITED — Major Shareholding Notification 2019

Feb 10, 2019

Form 604 Corporations Act 2001 Section 671B

Notice of Change of Interests of Substantial Holder

To: ADHERIUM LIMITED

ACN/ARSN:

1. Details of substantial holder (1)

Name: FIL Limited and the entities listed in Annexure A ("FIL") ACN/ARSN (if applicable)

There was a change in the interests of the substantial holder on The previous notice was given to the company on The previous notice was dated

06 February 2019 28 July 2016 28 July 2016

2. Previous and present voting power

The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows:

Class of	Previous Notice	Previous Notice	Present Notice	Present Notice
Securities (4)	Person’s votes	Voting Power (5)	Person’s votes	Voting Power (5)
COMMON	16,726,595	10.00%	14,745,815	8.46%
STOCK

3. Changes in relevant interests

Particulars of each change in, or change in the nature of, a relevant interest of the substantial holder or an associate in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows:

Date of	Person	Nature of	Consideration	Class and	Person’s votes
Acquisition	whose	change (6)	given in relation	number of	affected
	relevant		to change (7)	securities
	interest			affected
	changed
			AUD$	Common Stock	Common Stock
09-Mar-17	FIL	BUY	0.2116	73,429	73,429
10-Mar-17	FIL	BUY	0.2400	24,240	24,240
30-May-17	FIL	BUY	0.1610	205,495	205,495
31-May-17	FIL	BUY	0.1600	140,160	140,160
31-Oct-17	FIL	BUY	0.0910	129,586	129,586
31-Oct-17	FIL	BUY	0.0910	105,363	105,363
31-Oct-17	FIL	BUY	0.0910	246,916	246,916
31-Oct-17	FIL	SELL	0.0910	105,363	105,363
31-Oct-17	FIL	SELL	0.0910	246,916	246,916
31-Oct-17	FIL	SELL	0.0910	129,586	129,586
13-Feb-18	FIL	BUY	0.0870	136,220	136,220
13-Feb-18	FIL	SELL	0.0870	136,220	136,220

02-Jul-18	FIL	SELL	0.1200	45,000	45,000
06-Jul-18	FIL	SELL	0.1075	70,482	70,482
13-Jul-18	FIL	SELL	0.1002	878,863	878,863
03-Sep-18	FIL	BUY	0.0898	242,352	242,352
04-Sep-18	FIL	BUY	0.0900	525,318	525,318
06-Sep-18	FIL	BUY	0.0940	484,149	484,149
30-Jan-19	FIL	SELL	0.0330	413,971	413,971
01-Feb-19	FIL	SELL	0.0259	640,549	640,549
01-Feb-19	FIL	SELL	0.0259	287,145	287,145
01-Feb-19	FIL	SELL	0.0259	67,542	67,542
01-Feb-19	FIL	SELL	0.0259	109,764	109,764
04-Feb-19	FIL	SELL	0.0240	94,261	94,261
04-Feb-19	FIL	SELL	0.0240	42,255	42,255
04-Feb-19	FIL	SELL	0.0240	9,939	9,939
04-Feb-19	FIL	SELL	0.0240	16,152	16,152
06-Feb-19	FIL	SELL	0.0220	579,682	579,682
06-Feb-19	FIL	SELL	0.0220	259,860	259,860
06-Feb-19	FIL	SELL	0.0220	61,125	61,125
06-Feb-19	FIL	SELL	0.0220	99,333	99,333
			**Total Buys **	2,313,228	2,313,228
			Total Sells	(4,294,008)	(4,294,008)
			Total Net Sell	(1,980,780)	(1,980,780)

4. Present Relevant Interest

Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows:

Refer to Annexure A

5. Changes in Association

The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows:

Name and ACN/ARSN (if applicable) Nature of association N/A

6. Addresses

The addresses of persons named in this form are as follows:

Refer to Annexure A

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Sign Here ______

Dated: 08 February 2019 Jen Li Head of Regulatory Reporting, Asia Pacific Duly authorized under Powers of Attorney by and on behalf of FIL Limited

Annexure A

	Investment Manager	Address	Custodian	Nature of Relevant Interest	Sum of Numerator Shares
	FIL INVESTMENT	Level 11, 167	JP MORGAN,
					935,540
	MANAGEMENT	Macquarie Street,	BOURNEMOUTH(C)
	(AUSTRALIA) LIMITED	Sydney, NSW 2000,	NATIONAL ASTL BK
					220,058
		Australia	MELBOURNE(S)
			STATE STREET BANK
					357,618
			AND TR CO
	FIL INVESTMENT	Level 21, Two Pacific	BROWN BROS HARRIMN	Investment Discretion /
					10,773,692
	MANAGEMENT	Place, 88 Queensway,	LTD LUX(C)	Voting Power
	(HONG KONG)	Admiralty, Hong Kong	CLEARSTREAM BANKING
					371,950
	LIMITED		SA LUX(C)
	FIL PENSION	Oakhill House, 130
	MANAGEMENT	Tonbridge Road,
			HSBC BANK PLC (C)		2,086,957
		Hildenborough, Kent,
		England TN119DZ
	Grand Total				14,745,815