ADHERIUM LIMITED — Capital/Financing Update 2022

Oct 27, 2022

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28 October 2022

Companies Announcements Office ASX Limited

Adherium Limited Collins Square, Tower 4 Level 18, 727 Collins Street Melbourne VIC 3000 Australia

Level 2, 63 Albert Street Auckland 1010 New Zealand

Dear Sir/Madam

Cleansing notice under section 708A of the Corporations Act 2001 (Cth)

Today, 28 October 2022, Adherium Limited ACN 605 352 510 ( Company ) (ASX: ADR) completed the tranche 2 allotment of fully paid ordinary shares ( Shares ) under the placement to sophisticated and professional investors announced 16 September 2022. Details of the allotment are contained in the Appendix 2A filed by the Company today.

The Company gives notice pursuant to section 708A(5)(e) of the Corporations Act 2001 (Cth) (Act) that:

1. the Company issued the Shares without disclosure under Part 6D.2 of the Act;

2. as at the date of this notice, the Company has complied with the provisions of Chapter 2M of the Act as they apply to the Company and section 674 of the Act; and

3. as at the date of this notice there is no information:

   • a. that has been excluded from a continuous disclosure notice in accordance with the ASX Listing Rules; and

   • b. that investors and their professional advisers would reasonably require for the purpose of making an informed assessment of:

     • i. the assets and liabilities, financial position and performance, profits and losses and prospects of the Company; or

     • ii. the rights and liabilities attaching to the Shares.

Yours faithfully

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Rob Turnbull Joint Company Secretary

Adherium Limited (ACN 605 352 510) Collins Square, Tower 4, Level 18, 727 Collins Street Melbourne VIC 3000 Australia

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