ACHIEVE LIFE SCIENCES, INC. — Director's Dealing 2008

Dec 29, 2008

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ONCOGENEX PHARMACEUTICALS, INC. (OGXI)
CIK: 0000949858
Period of Report: 2008-12-23

Reporting Person: Cormack Scott Daniel (Director, President and CEO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2008-12-23	Common Stock	M	24809	$3.8915	Acquired	31115	Direct
2008-12-23	Common Stock	G	24809	$0.00	Disposed	6306	Direct
2008-12-23	Common Stock	G	24809	$0.00	Acquired	24809	Indirect

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2008-12-23	Employee Stock Option (Right to Buy)	$3.8915	M	24809	Disposed	2009-01-01	Common Stock (24809)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	1015	Indirect

Footnotes

F1: Scott D. Cormack and his spouse are the trustees and beneficiaries of the Trycor Investment Trust No 1.