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abrdn Healthcare Investors

Regulatory Filings Aug 28, 2012

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N-Q 1 a12-16528_1nq.htm N-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549
OMB Number: 3235-0578 Expires: April 30, 2013 Estimated average burden hours per response........5.6
FORM N-Q

*QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED MANAGEMENT INVESTMENT COMPANY*

Investment Company Act file number
H&Q Healthcare Investors
(Exact name of registrant as specified in charter)
2 Liberty Square, 9 th Floor, Boston, MA 02109
(Address of principal executive offices) (Zip code)
(Name and address of agent for service)
Registrant’s telephone number, including area code: 617-772-8500
Date of fiscal year end: September 30
Date of reporting period: 6/30/12

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*Item 1. Schedule of Investments.*

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*H&Q HEALTHCARE INVESTORS*

*SCHEDULE OF INVESTMENTS*

JUNE 30, 2012

(Unaudited)

SHARES VALUE
CONVERTIBLE SECURITIES AND WARRANTS – 6.1% of Net Assets
Convertible Preferred and Warrants (Restricted)(a) (b) – 6.0%
Biotechnologies/Biopharmaceuticals – 1.5%
2,380,953 Agilix Corporation Series B (c) $ 0
7,399,474 Celladon Corporation Series A-1 3,322,364
3,696,765 EBI Life Sciences, Inc. Series A (c) 16,266
3,696,765 Euthymics Biosciences, Inc. Series A (c) 3,392,521
358,852 MacroGenics, Inc. Series D 234,008
3,696,765 Neurovance, Inc. Series A (c) 287,608
7,252,767
Healthcare Services – 1.3%
5,384,615 PHT Corporation Series D (c) 5,007,691
1,204,495 PHT Corporation Series E (c) 1,120,180
149,183 PHT Corporation Series F (c) 138,740
6,266,611
Medical Devices and Diagnostics – 3.2%
3,424,756 CardioKinetix, Inc. Series C (c) 890,437
6,155,027 CardioKinetix, Inc. Series D (c) 677,053
12,177,507 CardioKinetix, Inc. Series E (c) 1,217,751
N/A CardioKinetix, Inc. warrants (expiration 12/11/19) (c) (d) 0
N/A CardioKinetix, Inc. warrants (expiration 6/03/20) (c) (d) 0
N/A CardioKinetix, Inc. warrants (expiration 7/07/21) (c) (d) 0
3,109,861 Dynex Technologies, Inc. Series A (c) 559,775
142,210 Dynex Technologies, Inc. warrants (expiration 4/01/19) (c) 0
11,335 Dynex Technologies, Inc. warrants (expiration 5/06/19) (c) 0
3,669,024 Labcyte, Inc. Series C 1,920,000
3,109,861 Magellan Diagnostics, Inc. Series A 1,834,818
142,210 Magellan Diagnostics, Inc. warrants (expiration 4/01/19) 0
11,335 Magellan Diagnostics, Inc. warrants (expiration 5/06/19) 0
1,547,988 OmniSonics Medical Technologies, Inc. Series A-1 1,548
1,263,099 OmniSonics Medical Technologies, Inc. Series B-1 1,263
13,823,805 Palyon Medical Corporation Series A (c) 2,211,809
N/A Palyon Medical Corporation warrants (expiration 4/26/19) (c) 0
65,217 TherOx, Inc. Series H 74,608
149,469 TherOx, Inc. Series I 170,992
4,720,000 Tibion Corporation Series B 2,360,000
3,750,143 Veniti, Inc. Series A (c) 3,244,999
15,165,053

The accompanying notes are an integral part of this schedule of investments.

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PRINCIPAL AMOUNT VALUE
Convertible Notes – 0.1%(a)
Medical Devices and Diagnostics – 0.1%
$ 737,500 Palyon Medical Corporation Cvt. Promissory Note, 8.00% due 4/26/13 (c) $ 737,500
TOTAL CONVERTIBLE SECURITIES AND WARRANTS (Cost $39,960,869) 29,421,931
SHARES
COMMON STOCKS AND WARRANTS – 86.2%
Biotechnologies/Biopharmaceuticals – 45.3%
37,331 Acorda Therapeutics, Inc. (b) 879,518
231,115 Alexion Pharmaceuticals, Inc. (b) 22,949,720
312,351 Alkermes plc (b) 5,300,596
135,778 Allergan, Inc. 12,568,969
694,195 Amarin Corporation plc (b) (f) 10,038,060
6,808 Amgen, Inc. 497,256
5,910,745 Antisoma plc (b) (e) 161,774
222,125 ARIAD Pharmaceuticals, Inc. (b) 3,822,771
105,260 Baxter International, Inc. 5,594,569
122,214 Biogen Idec, Inc. (b) 17,645,257
368,210 Celgene Corporation (b) 23,624,354
258,630 Ceres, Inc. (Restricted) (a) (b) 2,106,541
2,723 Ceres, Inc. warrants (Restricted, expiration 9/05/15) (a) (b) 1,688
117,921 Cubist Pharmaceuticals, Inc. (b) 4,470,385
290,824 Curis, Inc. (b) 1,570,450
271,379 Dendreon Corporation (b) 2,008,205
483,506 Elan Corporation plc (b) (f) 7,054,353
598,771 Gilead Sciences, Inc. (b) 30,704,977
216,815 Keryx Biopharmaceuticals, Inc. (b) 390,267
645,747 Nektar Therapeutics (b) 5,211,178
901,902 Neurocrine Biosciences, Inc. (b) 7,134,045
104,600 NPS Pharmaceuticals, Inc. (b) 900,606
763,600 Puma Biotechnology, Inc (b) 8,590,500
157,260 Regeneron Pharmaceuticals, Inc. (b) 17,962,237
431,250 Synta Pharmaceuticals Corporation (b) 2,358,938
138,505 United Therapeutics Corporation (b) 6,839,377
610,595 Verastem, Inc. (Restricted) (a) (b) 5,605,262
110,400 Vertex Pharmaceuticals, Inc. (b) 6,173,568
163,934 VIVUS, Inc. (b) 4,678,676
216,844,097
Drug Delivery – 2.5%
9,182,750 A.P. Pharma, Inc. (b) (c) 6,290,184
4,600,000 A.P. Pharma, Inc. warrants (Restricted, expiration 7/01/16) (a) (b) (c) 1,876,800

The accompanying notes are an integral part of this schedule of investments.

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SHARES VALUE
COMMON STOCKS AND WARRANTS – continued
Drug Delivery – continued
1,023,650 IntelliPharmaCeutics International, Inc. (b) (c) $ 3,296,153
460,200 IntelliPharmaCeutics International, Inc. warrants (Restricted, expiration 2/01/13) (a) (b) (c) 239,304
460,200 IntelliPharmaCeutics International, Inc. warrants (Restricted, expiration 2/01/16) (a) (b) (c) 303,732
12,006,173
Drug Discovery Technologies – 0.0%
70 Zyomyx, Inc. (Restricted) (a) (b) 18
Generic Pharmaceuticals – 12.9%
752,236 Akorn, Inc. (b) 11,862,762
267,306 Impax Laboratories, Inc. (b) 5,418,292
501,580 Mylan, Inc. (b) 10,718,764
151,532 Perrigo Company 17,870,169
285,177 Teva Pharmaceutical Industries Ltd. (f) 11,247,381
63,135 Watson Pharmaceuticals, Inc. (b) 4,671,359
61,788,727
Healthcare Services – 5.5%
98,818 Aetna, Inc. 3,831,174
222,222 Aveta, Inc. (Restricted) (a) (g) 2,499,998
96,600 Covance, Inc. (b) 4,622,309
95,406 CVS Caremark Corporation 4,458,322
56,862 McKesson Corporation 5,330,813
94,213 UnitedHealth Group, Inc. 5,511,460
26,254,076
Medical Devices and Diagnostics – 9.7%
463,627 Accuray, Inc. (b) 3,171,209
351,726 Alere, Inc. (b) 6,837,553
170,368 Bruker Corporation (b) 2,267,598
160,000 Ceracor Laboratories, Inc. (Restricted) (a) (b) 77,027
93,544 Gen-Probe, Inc. (b) 7,689,317
471,139 Hologic, Inc. (b) 8,499,348
51,173 iCAD, Inc. (b) 23,540
171,804 iCAD, Inc. (Locked-up until 6/30/12) (Restricted) (a) (b) 75,078
38,181 iCAD, Inc. (Locked-up until 12/31/12) (Restricted) (a) (b) 15,807
38,597 IDEXX Laboratories, Inc. (b) 3,710,330
62,208 Illumina, Inc. (b) 2,512,581
98,000 Life Technologies Corporation (b) 4,409,020
830,292 Medwave, Inc. (b) (c) 0
93,008 OmniSonics Medical Technologies, Inc. (Restricted) (a) (b) 93
91,019 Palomar Medical Technologies, Inc. (b) 773,661
208 Songbird Hearing, Inc. (Restricted) (a) (b) 139
121,215 Thermo Fisher Scientific, Inc. 6,292,271
46,354,572

The accompanying notes are an integral part of this schedule of investments.

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SHARES VALUE
COMMON STOCKS AND WARRANTS – continued
Pharmaceuticals – 10.3%
132,887 Endo Pharmaceuticals Holdings, Inc. (b) $ 4,116,839
247,365 Ironwood Pharmaceuticals, Inc. (b) 3,408,690
64,745 Jazz Pharmaceuticals, Inc. (b) 2,914,172
114,358 Medivation, Inc. (b) 10,452,321
318,630 Merck & Company, Inc. 13,302,803
56,068 Sanofi, CVR (expiration 12/31/20) (b) (h) 79,056
89,340 Shire plc (f) 7,718,083
401,482 Warner Chilcott plc (b) 7,194,557
49,186,521
TOTAL COMMON STOCKS AND WARRANTS (Cost $332,317,505) 412,434,184
EXCHANGE TRADED FUND – 1.3%
47,741 iShares Nasdaq Biotechnology Index Fund 6,204,182
TOTAL EXCHANGE TRADED FUND (Cost $4,187,923) 6,204,182
PRINCIPAL AMOUNT
SHORT-TERM INVESTMENT – 4.6%
$ 22,287,000 Repurchase Agreement, State Street Bank and Trust Co., repurchase value $22,287,019, 0.01%, dated 06/29/12, due 07/02/12 (collateralized by U.S. Treasury Note 1.75%, due 05/31/16, market value $22,734,017) 22,287,000
TOTAL SHORT-TERM INVESTMENT (Cost $22,287,000) 22,287,000
TOTAL INVESTMENTS BEFORE MILESTONE INTERESTS - 98.2% (Cost $398,753,297) 470,347,297
INTEREST
MILESTONE INTERESTS (Restricted)(a) (b) – 1.8%
Biotechnologies/Biopharmaceuticals – 1.0%
1 Targegen Milestone Interest 5,024,301
Medical Devices and Diagnostics – 0.8%
1 Interlace Medical Milestone Interest 3,087,040
1 Xoft Milestone Interest 890,680
3,977,720
TOTAL MILESTONE INTERESTS (Cost $6,116,063) 9,002,021
TOTAL INVESTMENTS - 100.0% (Cost $404,869,360) 479,349,318
OTHER LIABILITIES IN EXCESS OF ASSETS - 0.0% (218,900 )
NET ASSETS - 100% $ 479,130,418

The accompanying notes are an integral part of this schedule of investments.

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(a) Security fair valued.

(b) Non-income producing security.

(c) Affiliated issuers in which the Fund holds 5% or more of the voting securities (total market value of $31,508,503).

(d) Number of warrants to be determined at a future date.

(e) Foreign Security.

(f) American Depository Receipt

(g) Security exempt from registration under Rule 144A of the Securities Act of 1933, as amended. These securities may be resold in transactions exempt from registration, normally to qualified institutional buyers.

(h) Contingent Value Rights

The accompanying notes are an integral part of this schedule of investments.

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*H&Q HEALTHCARE INVESTORS*

*NOTES TO SCHEDULE OF INVESTMENTS*

June, 30, 2012

(continued)

(unaudited)

**Other Information****

The Fund uses a three-tier hierarchy to prioritize the assumptions, referred to as inputs, used in valuation techniques to measure fair value. The three-tier hierarchy of inputs is summarized in three broad levels. Level 1 includes quoted prices in active markets for identical investments. Level 2 includes prices determined using other significant observable inputs (including quoted prices for similar investments, interest rates, credit risk, etc.). Level 3 includes prices determined using significant unobservable inputs (including the Fund’s own assumptions in determining the fair value of investments). These inputs or methodology used for valuing securities are not necessarily an indication of the risk associated with investing in those securities.

The following is a summary of the inputs used as of June 30, 2012 to value the Fund’s net assets. For the period ended June 30, 2012, there were no transfers between Levels 1 and 2.

Assets at Value Level 1 Level 2 Level 3 Total
Convertible Securities and Warrants
Biotechnologies/Biopharmaceuticals $ 7,252,767 $ 7,252,767
Healthcare Services 6,266,611 6,266,611
Medical Devices and Diagnostics 15,902,553 15,902,553
Common Stocks and Warrants
Biotechnologies/Biopharmaceuticals $ 209,130,606 7,713,491 216,844,097
Drug Delivery 9,586,337 2,419,836 12,006,173
Drug Discovery Technologies — 18 18
Generic Pharmaceuticals 61,788,727 — 61,788,727
Healthcare Services 23,754,078 2,499,998 26,254,076
Medical Devices and Diagnostics 46,186,428 168,144 46,354,572
Pharmaceuticals 49,186,521 — 49,186,521
Exchanged Traded Fund 6,204,182 — 6,204,182
Short-Term Investment — $ 22,287,000 — 22,287,000
Milestone Interests
Biotechnologies/Biopharmaceuticals — — 5,024,301 5,024,301
Medical Devices and Diagnostics — — 3,977,720 3,977,720
Other Assets — — 2,027,245 2,027,245
Total $ 405,836,879 $ 22,287,000 $ 53,252,684 $ 481,376,563

The following is a reconciliation of level 3 assets for which significant unobservable inputs were used to determine fair value.

Level 3 Assets Balance as of September 30, 2011 Realized gain/loss and change in unrealized appreciation (depreciation) Cost of purchases Proceeds from sales Net transfers in (out of) Level 3 Balance as of June 30, 2012
Convertible Securities and Warrants
Biotechnologies/Biopharmaceuticals $ 3,065,658 $ (22,392 ) $ 4,544,170 $ (334,669 ) $ — $ 7,252,767
Drug Discovery Technologies 4,902,442 (1,179,884 ) 43 (3,722,601 ) — 0
Healthcare Services 5,255,869 1,010,742 — — — 6,266,611
Medical Devices and Diagnostics 25,318,191 (846,478 ) 1,830,467 (10,399,627 ) — 15,902,553
Common Stocks and Warrants
Biotechnologies/Biopharmaceuticals — (1,181,740 ) 8,914,434 (19,203 ) — 7,713,491
Drug Delivery 1,477,002 942,503 331 — — 2,419,836
Drug Discovery Technologies 18 — — — — 18
Healthcare Services 1,999,998 500,000 — — — 2,499,998
Medical Devices and Diagnostics 201,816 34,803 — (68,475 ) — 168,144
Milestone Interests
Biotechnologies/Biopharmaceuticals 6,659,002 36,088 — (1,670,789 ) — 5,024,301
Medical Devices and Diagnostics 4,927,637 1,834,486 892 (2,785,295 ) — 3,977,720
Other Assets 1,076,814 — 1,640,249 (689,818 ) — 2,027,245
Total $ 54,884,447 $ 1,128,128 $ 16,930,586 $ (19,690,477 ) $ — $ 53,252,684
Net change in unrealized appreciation (depreciation) from investments still held as of June 30, 2012 $ 2,302,293

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The following is a quantitative disclosure about significant unobservable inputs used in the determination of the fair value of level three assets.

Fair Value at 6/30/12 Valuation Technique Unobservable Input Range
Private Companies and Other Restricted Securities $ 12,801,237 Public market price based Estimate of time to liquidity 3-9 months
Discount for lack of marketability 5%-10%
14,626,520 Capital asset pricing model based Revenue growth rate 17%-117%
Price to sales multiple 1.7-8.0
14,558,593 Independent valuation based (1) (1)
11,266,334 Probability adjusted value based Probability of events 10%-50%
Timing of events 0.5-6 years
$ 53,252,684

(1) Valuation prepared by an independent third party. ASC 820-10-50-2(bbb) states that entities are not required to create “quantitative unobservable inputs [that] are not developed by the reporting entity.”

**Investment Valuation****

Shares of publicly traded investments listed on national securities exchanges or in the over-the-counter market are typically valued at the last sale price, as of the close of trading, generally 4 p.m., Eastern time. The Trustees have established and approved fair valuation policies and procedures with respect to securities for which effective quoted prices may not be available. Shares of publicly traded investments for which market quotations are not readily available, such as stocks for which trading has been halted or for which there are no current day sales, or whose quoted price may otherwise not reflect fair value are valued in good faith by the Adviser using a fair valuation process described below. Restricted securities of companies that are publicly traded are valued typically based on the closing market quote on the valuation date adjusted for the impact of the restriction as determined in good faith by the Adviser also using the fair valuation process described below. Non-traded warrants of publicly traded companies are typically valued using the Black-Scholes model, which incorporates both observable and unobservable inputs. Short-term investments with a maturity of 60 days or less are valued at amortized cost, which approximates fair value.

Convertible preferred shares, warrants or convertible note interests in private companies, milestone interests, other restricted securities, as well as shares of publicly traded companies for which market quotations are not available or which do not reflect fair value, are typically valued in good faith, based upon the recommendations made by the Adviser pursuant to fair valuation policies and procedures approved by the Trustees. The Adviser has a Valuation Sub-Committee comprised of senior management which reports to the Valuation Committee of the Board at least quarterly. Each fair value determination is based on a consideration of relevant factors. Factors the Adviser considers may include (i) the existence of any contractual restrictions on the disposition of securities; (ii) information obtained from the company, which may include an analysis of the company’s financial statements, the company’s products or intended markets or the company’s technologies; (iii) the price of a security negotiated at arm’s length in an issuer’s completed subsequent round of financing; (iv) the price and extent of public trading in similar securities of the issuer or of comparable companies; or (v) a probability and time value adjusted analysis of contractual term. Where appropriate, multiple valuation methodologies are applied to confirm fair value. Significant unobservable inputs are identified by the Adviser and used in the fair value determination. A significant change in any of these inputs may result in a significant change in the fair value measurement. Due to the uncertainty inherent in the valuation process, despite the Adviser’s good faith effort, such estimates of fair value may differ significantly from the values that would have been used had a ready market for the investments existed, and differences could be material. Additionally, changes in the market environment and other events that may occur over the life of the investments may cause the gains or losses ultimately realized on these investments to be different from the valuations currently assigned.

**Federal Income Tax Cost****

At June 30, 2012, the cost of securities for Federal income tax purposes was $404,869,360. The net unrealized gain on securities held by the Fund was $74,479,958, including gross unrealized gain of $114,861,095 and gross unrealized loss of $40,381,137.

**Other Transactions with Affiliates****

An affiliate company is a company in which the Fund holds 5% or more of the voting securities. Transactions with such companies during the period ended June 30, 2012 were as follows:

Issuer Value on September 30, 2011 Purchases Sales Income Value on June 30, 2012
Agilix Corporation $ 3,952 $ 3,966 $ — $ 0
A.P . Pharma, Inc. 2,944,000 — — 8,166,984
CardioKinetix , Inc. 2,785,241 — — 2,785,241
Concentric Medical, Inc. 10,153,138 10,113,758 — —
Dynex Technologies, Inc. — $ 287,844 — — 559,775
EBI Life Sciences, Inc. — 63,886 44,320 — 16,266
Euthymics Biosciences, Inc. 2,831,651 848,288 284,099 — 3,392,521
IntelliPharmaCeutics International, Inc. 4,008,342 283,938 — — 3,839,189
Medwave , Inc. 2,491 — — — —
Neurovance , Inc. — 297,837 6,250 — 287,608
Palyon Medical Corporation 2,211,809 737,500 — — 2,949,309
PHT Corporation 5,255,869 — — — 6,266,611
Veniti , Inc. 3,244,999 — — — 3,244,999
$ 33,441,492 $ 2,519,293 $ 10,452,393 $ — $ 31,508,503

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**Private Companies and Other Restricted Securities****

The Fund may invest in private companies and other restricted securities if these securities would currently comprise 40% or less of net assets. The value of these securities represents 11% of the Fund’s net assets at June 30, 2012.

At June 30, 2012, the Fund had commitments of $967,147 relating to additional investments in four private companies.

The following table details the acquisition date, cost, carrying value per unit, and value of the Fund’s private companies and other restricted securities at June 30, 2012. The Fund on its own does not have the right to demand that such securities be registered.

Security (#) Acquisition — Date Cost Carrying Value — per Unit Value
Agilix Corporation
Series B Cvt. Pfd. 11/08/01 $ 2,347,727 $ 0.00 $ 0
A.P . Pharma, Inc.
Warrants (expiration 7/01/16) 6/30/11 1,236 0.41 1,876,800
Aveta , Inc.
Common 12/21/05 3,004,731 11.25 2,499,998
CardioKinetix , Inc.
Series C Cvt. Pfd. 5/22/08 2,378,400 0.26 890,437
Series D Cvt. Pfd. 12/10/10 784,228 0.11 677,053
Series E Cvt. Pfd. 9/14/11 1,156,249 0.10 1,217,751
Warrants (expiration 12/11/19) 12/10/09, 2/11/10 177 0.00 0
Warrants (expiration 6/03/20) 6/03/10, 9/01/10 177 0.00 0
Warrants (expiration 7/07/21) 7/07/11 69 0.00 0
Celladon Corporation
Series A-1 Cvt. Pfd. 1/27/12 3,334,159 0.45 3,322,364
Ceracor Laboratories, Inc.
Common 3/31/98 0 0.48 77,027
Ceres, Inc.
Common 2/24/12 †† 3,719,242 8.15 2,106,541
Warrants (expiration 9/05/15) 9/05/07 28 0.62 1,688
Dynex Technologies, Inc.
Series A Cvt. Pfd. 1/03/2012 †† 287,751 0.18 559,775
Warrants (expiration 4/01/19) 1/03/2012 †† 86 0.00 0
Warrants (expiration 5/06/19) 1/03/2012 †† 7 0.00 0
EBI Life Sciences, Inc.
Series A Cvt. Pfd. 12/29/11 †† 19,566 0.00 † 16,266
Euthymics Biosciences, Inc.
Series A Cvt. Pfd. 7/14/10 - 5/21/12 3,405,183 0.92 3,392,521
iCAD , Inc.
Common (Locked-up until 6/30/12) 1/05/11 †† 259,486 0.44 75,078
Common (Locked-up until 12/31/12) 1/05/11 †† 0 0.41 15,807
IntelliPharmaCeutics International, Inc.
Warrants (expiration 2/01/13) 1/31/11 165 0.52 239,304
Warrants (expiration 2/01/16) 1/31/11 165 0.66 303,732
Interlace Medical
Milestone Interest 1/14/11 1,080,376 3,087,040 3,087,040
Labcyte , Inc.
Series C Cvt. Pfd. 7/18/05 1,924,893 0.52 1,920,000
MacroGenics , Inc.
Series D Cvt. Pfd. 9/04/08 1,318,295 0.65 234,008
Magellan Diagnostics, Inc.
Series A Cvt. Pfd. 11/28/06 - 10/01/09 1,762,968 0.59 1,834,818
Warrants (expiration 4/01/19) 4/03/09 515 0.00 0
Warrants (expiration 5/06/19) 5/12/09 41 0.00 0
Neurovance , Inc.
Series A Cvt. Pfd. 12/29/11 †† 291,587 0.08 287,608
OmniSonics Medical Technologies, Inc.
Series A-1 Cvt. Pfd. 10/01/03 1,801,555 0.00 † 1,548
Series B-1 Cvt. Pfd. 6/04/07, 11/15/07 961,365 0.00 † 1,263
Common 5/24/01, 7/02/07 2,409,096 0.00 † 93
Palyon Medical Corporation
Series A Cvt. Pfd. 4/28/09 2,967,404 0.16 2,211,809
Warrants (expiration 4/26/19) 4/25/12 0 0.00 0
Cvt. Promissory Note 4/25/12 737,500 1.00 737,500
PHT Corporation
Series D Cvt. Pfd. 7/23/01 4,206,263 0.93 5,007,691
Series E Cvt. Pfd. 9/12/03 - 10/19/04 941,783 0.93 1,120,180
Series F Cvt. Pfd. 7/21/08 122,594 0.93 138,740
Songbird Hearing, Inc.
Common 12/14/00 3,004,861 0.67 139
Targegen
Milestone Interest 7/20/10 4,192,557 5,024,301 5,024,301
TherOx , Inc.
Series H Cvt. Pfd. 9/11/00, 8/21/07 3,002,748 1.14 74,608
Series I Cvt. Pfd. 7/08/05 579,958 1.14 170,992
Tibion Corporation
Series B Cvt. Pfd. 2/23/11 2,366,726 0.50 2,360,000
Veniti , Inc.
Series A Cvt. Pfd. 2/28/11 3,260,896 0.87 3,244,999
Verastem , Inc
Common 1/27/12 †† 5,175,943 9.18 5,605,262
Xoft
Milestone Interest 1/05/11 843,130 890,680 890,680
Zyomyx , Inc.
Common 2/19/99 - 1/12/04 3,902,233 0.25 18
$ 67,554,119 $ 51,225,439

(#) See Schedule of Investments and corresponding footnotes for more information on each issuer.

† Carrying value per unit is greater than $0.00 but less than $0.01.

†† Interest received as part of a corporate action for a previously owned sccurity.

SEQ.=1,FOLIO='',FILE='C:\JMS\105546\12-16528-1\task5525929\16528-1-bk-03.htm',USER='105546',CD='Aug 28 04:55 2012'

*Item 2. Controls and Procedures.*

(a.) The registrant’s principal executive officer and principal financial officer have concluded, based on their evaluation of the registrant’s disclosure controls and procedures as conducted within 90 days of the filing date of this report, that these disclosure controls and procedures are adequately designed and are operating effectively to ensure that information required to be disclosed by the registrant on Form N-Q is (i) accumulated and communicated to the investment company’s management, including its certifying officers, to allow timely decisions regarding required disclosure; and (ii) recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission’s rules and forms.

(b.) There were no changes in the registrant’s internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act) that occurred during the registrant’s last fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting.

*Item 3. Exhibits.*

Separate certifications for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the Act (17 CFR 270.30a-2(a)). Filed herewith.

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*SIGNATURES*

Pursuant to the requirements of the Securities and Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

(Registrant)
By (Signature and Title) /s/ Daniel R. Omstead
Daniel R. Omstead, President
Date 8/28/2012

Pursuant to the requirements of the Securities and Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By (Signature and Title)
Laura Woodward, Treasurer
Date 8/28/2012

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