Valbiotis

Legal Proceedings Report • Mar 8, 2021

VALBIOTIS selected to present TOTUM-854's results on arterial hypertension at the annual meeting of the European Society of Hypertension (ESH) and the International Society of Hypertension (ISH) in April 2021

Preclinical results with the active substance TOTUM-854 on arterial hypertension, obtained through work undertaken as part of an academic partnership with Avignon University's Laboratoire de Pharm-Ecologie Cardiovasculaire (LAPEC) as well as at the Riom R&D platform.

A first international scientific acknowledgement for TOTUM-854 by a major cardiovascular congress.

TOTUM-854 to be the third active substance in the VALBIOTIS pipeline to enter the clinical development phase, in 2021.

La Rochelle, March 8, 2021 (5:40 pm CET) VALBIOTIS (FR0013254851 - ALVAL, eligible for the PEA/SME), a Research & Development company committed to scientific innovation for preventing and combating metabolic diseases, announces that the preclinical results obtained with TOTUM-854 for arterial hypertension have been selected by the European Society of Hypertension (ESH) and the International Society of Hypertension (ISH).

These results, achieved through work undertaken as part of the academic partnership between VALBIOTIS and the University of Avignon, as well as at the Riom R&D platform, will be presented during the annual ESH-ISH Joint Meeting, which will be held virtually from 11 to 14 April 2021.

"We are thrilled about the selection of these results with TOTUM-854 on high blood pressure for the annual meeting of ESH and ISH, two key learned societies for arterial hypertension around the world. This selection recognizes first and foremost our successful partnership on TOTUM-854 with the University of Avignon. For VALBIOTIS, this marks the first international scientific presentation at a congress dedicated to arterial hypertension. It demonstrates the relevance of our R&D approach in this domain. We take this as a very positive sign for the clinical development of TOTUM-854, a promising active substance in the fight against high blood pressure and the risk of cardiovascular diseases."

Pascal SIRVENT Member of the Management Board, Head of Discovery, Preclinical and Translational Research Department at VALBIOTIS

Details about the results will be revealed at the annual ESH-ISH meeting, which will be held virtually from 11 to 14 April 2021.

ABOUT VALBIOTIS

VALBIOTIS is a Research & Development company committed to scientific innovation for preventing and combating metabolic diseases in response to unmet medical needs.

VALBIOTIS has adopted an innovative approach, aiming to revolutionize healthcare by developing a new class of nutritional health solutions designed to reduce the risk of major metabolic diseases, based on a multi-target approach and made possible by the use of plant-based ingredients.

Its products are intended to be licensed to players in the health world.

VALBIOTIS was founded in La Rochelle in early 2014 and has formed numerous partnerships with top academic centers. The Company has established three sites in France – Périgny, La Rochelle (17) and Riom (63).

VALBIOTIS is a member of the "BPI Excellence" network and received the «Innovative Company» status accorded by BPI France. VALBIOTIS has also been awarded "Young Innovative Company" status and has received major financial support from the European Union for its research programs by obtaining support from the European Regional Development Fund (ERDF). VALBIOTIS is a PEA-SME eligible company.

Find out more about VALBIOTIS: www.valbiotis.com

CONTACTS

CORPORATE COMMUNICATION I VALBIOTIS

Carole ROCHER / Marc DELAUNAY +33 5 46 28 62 58 I media@valbiotis.com

FINANCIAL COMMUNICATION I ACTIFIN

Stéphane RUIZ +33 1 56 88 11 14 I sruiz@actifin.fr

This press release contains forward-looking statements about VALBIOTIS' objectives, based on rational hypotheses and the information available to the company at the present time. However, in no way does this constitute a guarantee of future performance, and these projections can be reconsidered based on changes in economic conditions and financial markets, as well as a certain number of risks and doubts, including those described in the VALBIOTIS core document, filed with the French Financial Markets Regulator (AMF) on 31 July 2020 (application number R20-018), these documents being available on the Company's website (www.valbiotis.com).

This press release, as well as the information contained herein, does not constitute an offer to sell or subscribe to, or a solicitation to purchase or subscribe to, VALBIOTIS' shares or securities in any country.

Name: VALBIOTIS - ISIN code: FR0013254851 - Mnemonic code: ALVAL EnterNext© PEA-PME 150