GenSight Biologics S.A.

Regulatory Filings • Apr 29, 2022

Press Release

GenSight Biologics Announces the Filing of its 2021 Universal Registration Document

Paris, France, Friday April 29, 2022, 5:45 pm CEST – GenSight Biologics (Euronext: SIGHT, ISIN: FR0013183985, PEA-PME eligible), a biopharma company focused on developing and commercializing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, today announced the filing of its 2021 Universal Registration Document (URD) in English with the French market authority (Autorités des Marchés Financiers, or AMF) under the reference D.22-0390.

The universal registration document notably includes:

• the 2021 annual financial report;
• the management report;
• the report on corporate governance; and
• the description of the share buyback program.

This universal registration document may be consulted on the Company's website (www.gensightbiologics.com), "Investors" section, and on the AMF's website (www.amf-france.org).

Contacts

GenSight Biologics

Corporate Communications Director Clothilde Caillet ccaillet@gensight-biologics.com

LifeSci Advisors

Investor Relations Guillaume van Renterghem gvanrenterghem@lifesciadvisors.com +41 (0)76 735 01 31

RooneyPartners

Media Relations Jeanene Timberlake jtimberlake@rooneypartners.com +1 646-770-8858

Orpheon Finance

Retail Investors James Palmer j.palmer@orpheonfinance.com +33 (0)7 60 92 77 74

About GenSight Biologics

GenSight Biologics S.A. is a clinical-stage biopharma company focused on developing and commercializing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders. GenSight Biologics' pipeline leverages two core technology platforms, the Mitochondrial Targeting Sequence (MTS) and optogenetics, to help preserve or restore vision in patients suffering from blinding retinal diseases. GenSight Biologics' lead product candidate, LUMEVOQ® (GS010; lenadogene nolparvovec), has been submitted for marketing approval in Europe for the treatment of Leber Hereditary Optic Neuropathy (LHON), a rare mitochondrial disease affecting primarily teens and young adults that leads to irreversible blindness. Using its gene therapy-based approach, GenSight Biologics' product candidates are designed to be administered in a single treatment to each eye by intravitreal injection to offer patients a sustainable functional visual recovery.