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Thor Medical ASA

Regulatory Filings Nov 20, 2025

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Thor Medical enters supply agreement with NucliThera for thorium-228

Thor Medical enters supply agreement with NucliThera for thorium-228

20.11.2025 07:30:01 CET | Thor Medical ASA | Non-regulatory press releases

Oslo, 20 November 2025 - Thor Medical ASA has signed a five-year frame agreement

to supply NucliThera AS with thorium-228 (Th-228). The isotope will be used in

NucliThera's development programs for hematological cancers.

Led by Dr. Roy H. Larsen and Professor Emeritus Øyvind S. Bruland, NucliThera's

research team is advancing an early-stage development program targeting

hematological cancers such as lymphoma and leukemia.

"We are working to develop targeted radionuclide therapies that can help cancer

patients with a high unmet medical need. Reliable access to high-purity

alpha-emitters is essential to advance these development programs, and with Thor

Medical we expect to have a dependable domestic supplier of high-quality

material," says Dr. Roy H. Larsen, Co-Founder and Chair of NucliThera AS.

Dr. Larsen and Professor Bruland were jointly leading the development of the

only alpha-emitting cancer pharmaceutical that so far has been approved by FDA -

Xofigo for metastasized prostate cancer.

"We are proud to support NucliThera's development program. Oslo has a strong and

growing radiopharmaceutical community and ecosystem, and we are excited to be

working with experienced industry leaders such as Dr. Larsen and Professor

Bruland," says Jasper Kurth, CEO of Thor Medical.

The thorium-228 will be supplied from AlphaOne, Thor Medical's first

commercial-scale isotope production facility, on track to begin operations in

2026. The supply agreement further adds to existing supply agreements for

thorium-228 with Telix Pharmaceuticals, Oncoinvent, AdvanCell, ARTBIO, and two

additional undisclosed partners.

In 2023, Thor Medical and NucliThera entered an agreement to transfer the former

Nordic Nanovector's pipeline of patents ("Nanovector Patents") to NucliThera.

Subject to the terms of the agreement, NucliThera AS assumed full ownership to

the Nanovector Patents with Thor Medical retaining interest through an

undisclosed profit-sharing in the event of successful commercialization of the

patents. NucliThera continues the efforts to commercialize some of the patents,

in addition to other new development programs in the company.

CONTACTS

Brede Ellingsæter, CFO and COO, Thor Medical ASA, +47 472 38 440,

[email protected]

ABOUT THOR MEDICAL ASA

Thor Medical is an emerging supplier of radionuclides, primarily alpha particle

emitters, from naturally occurring thorium. Its proprietary production process

requires no irradiation or use of nuclear reactors, and provides reliable,

environmentally friendly, cost-efficient supply of alpha-emitters for the

radiopharmaceutical industry. Thor Medical is headquartered in Oslo, Norway and

listed on the Oslo Stock Exchange under the ticker symbol 'TRMED'. To learn

more, visit www.thormedical.com - http://visitwww.thormedical.com -

http://visitwww.thormedical.com.

ABOUT NUCLITHERA AS

NucliThera is an R&D company developing targeted short, range radionuclides for

treating hematological cancers like lymphoma and leukemia. High-energy alpha-

and beta-radiating nuclides are linked to targeting monoclonal antibodies or

small molecules. They bind to cancer cells killing them with minimal damage to

surrounding healthy tissue.

The NucliThera research team is led by Dr. Roy H Larsen and Professor Emeritus

Øyvind S Bruland. They have developed the only alpha-emitting cancer

pharmaceutical approved by FDA so far - Xofigo against bone metastases from

prostate cancer. Xofigo was acquired by Bayer Healthcare for US$ 2.9 billion in

ATTACHMENTS

Download announcement as PDF.pdf -

https://kommunikasjon.ntb.no/ir-files/17848634/18725924/6588/Download%20announce

ment%20as%20PDF.pdf

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