XTL Biopharmaceuticals Ltd.

Regulatory Filings • Nov 21, 2007

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C002��� �� �� ������������� ��"�2PublicX T L BIOPHARMACEUTICALS LTD4313Corporation no: 520039470Stock Exchange/Market: ��� �� ��1996380Hasapir 3 , Nes Ziona 76100 , ,Tel: 08-9304444 , Fax: 08-9304445E.mail address: rcohen@xtlbio.comDate of transmission: 21/11/2007              Time of broadcast: 10:40 10:34:58

Reference: 2007-02-450292

Israel Securities Authority		Tel Aviv Stock Exchange
www.isa.gov.il		www.tase.co.il

Immediate ReportRegulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

The corporation is a foreign private issuer as defined by U.S. Securities Laws.
Attached hereto is a report on A second amendment to the Company's registration statment on form F-3 was filed with the Securities and Exchange Commission.
vsecondamendmentF3_isa.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
Previous names of reporting entity: XENOGRAFT TECHNOLOGIES LTD
Date of revision of form structure: 31/10/2007
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Name of the Signatory: : Kantor Ronen , , Position of Signatory in the reporting corporation: Legal Consultant & Corporate Secretary
Abba Hillel Silver Telephone: 03-6133371 , Facsimile: 03-6133372 , E-mail: rkantor@kantor-law.com 2