Compugen Ltd.

Foreign Filer Report • Dec 20, 2007

_________ false

C002�������� ��"�2PublicCOMPUGEN LTD.6267Corporation no: 511779639Stock Exchange/Market: ��������606380Pinchas Rosen 72 , Tel Aviv 69512 , ,Tel: 03-7658585 , 03-7658525 Fax: 03-7658555E.mail address: amos@compugen.co.ilDate of transmission: 20/12/2007              Time of broadcast: 14:01 13:42:08

Reference: 2007-02-487747

Israel Securities Authority		Tel Aviv Stock Exchange
www.isa.gov.il		www.tase.co.il

Immediate ReportRegulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

The corporation is a foreign private issuer as defined by U.S. Securities Laws.
Attached hereto is a report on Compugen and Roche sign Agreement to Identify Genetic Variations Predictive of Drug Response in Rheumatoid Arthritis Patients
6-kdecember202007_isa.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
Previous names of reporting entity:
Date of revision of form structure: 02/12/2007
- - -
Name of the Signatory: : Bart Rachel , , Position of Signatory in the reporting corporation: General Counsel
Pinchas Rosen Telephone: 03-7658107 , Facsimile: 03-7658555 , E-mail: rachelb@compugen.co.il 2