OPKO Health Inc.

Regulatory Filings • Dec 22, 2020

FORM 3 UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

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INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person				2. Date of Event Requiring 3. Issuer Name and Ticker or Trading Symbol
Medel	Roger	J.	M.D. Statement (Month/Day/Year)		OPKO Health, Inc. [OPK]
(Last) 4400 Biscayne Blvd.	(First)	(Middle)		12/18/2020		4. Relationship of Reporting Person(s) to (Check all applicable)		5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)					____ 10% Owner X Director			6. Individual or Joint/Group Filing (Check
Miami	FL	33137				_ Officer (give title _ Other (specify below)		Applicable Line) X
(City)	(State)	(Zip)						Form filed by One Reporting Person ____ Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)			2. Amount of Securities Beneficially Owned (Instr. 4)		3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned ( e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative	5. Ownership Form of Derivative	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	Security	Security: Direct (D) or Indirect (I) (Instr. 5)

Explanation of Responses:

Steven D. Rubin, Attorney-in-Fact 12/21/2020

**Signature of Reporting Person Date

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

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