Keep the world sweet

This presentation was prepared by Bee-io honey Ltd. (the "Company"), and is given to you only for the provision of concise information for the sake of convenience, and may not be copied or distributed to any other person. The data and information included in this presentation should not be interpreted as advice and should not be relied on for any purpose. Such data and information should not be copied or used except as expressly permitted in writing. This presentation does not purport to be comprehensive or to contain any and all information which might be relevant in connection with the making of a decision on an investment in securities of the Company. No explicit or implicit representation or undertaking is given by any person regarding the accuracy or integrity of any information included in this presentation. In particular, no representation or undertaking is given regarding the realization or reasonableness of any forecasts regarding the future chances of the Company. To obtain a full picture of the activities of the Company and the risks entailed thereby, see the full immediate and periodic reports filed in connection with the Company with the Israel Securities Authority and the Tel Aviv Stock Exchange Ltd., including warnings regarding forward-looking information, as defined in the Securities Law, 5728-1968, included therein. The forward-looking information in the presentation may not materialize, in whole or in part, or may materialize differently than expected, or may be affected by factors that cannot be assessed in advance. For the avoidance of doubt, it is clarified that the Company do not undertake to update and/or modify the information included in the presentation to reflect events and/or circumstances occurring after the date of preparation of the presentation. This presentation is not an offer or invitation to buy or subscribe for any securities. This presentation and anything contained herein are not a basis for any contract or undertaking, and are not to be relied upon in such context. The information provided in the presentation is not a basis for the making of any investment decision, nor a recommendation or an opinion, nor a substitute for the discretion of a potential investor.

FORWARD LOOKING STATEMENT

Bee-io produces honey without bees in a process that combines natural nectar flowers with unique biological processes that turn the nectar into honey.

The demand for honey continues to rise along with population growth. Honey is a miraculous product, the fruit of a unique interaction between the plant and animal kingdoms.

Bees are perfectly adapted to pollinate, helping plants grow, breed and produce food. They do so by transferring pollen between flowering plants and therefore keeping the cycle of life turning.

There is growing public and political concern at bee decline across the world that includes loss of habitat and food sources, exposure to pesticides, and the effects of climate breakdown.

INTRODUCTION

DECEMBER 2021

ABOUT US

OUR TEAM

Ofir (B.Sc. in Engineering form the Ben Gurion University and M.Sc in Economics from the Hebrew University) has over 12 years of experience leading the development of military and commercial products, from initial concept to a complete and final product. In the past 5 years leading GKI Group's technological innovations while building and managing three start-up companies.

Dr. Efrat Dvash Riesenfeld earned her PhD In Molecular Genetics from the Weizmann Institute of Science (2015). Efrat was awarded an American Diabetes Association fellowship and conducted her postdoctoral research at Harvard Medical School (2018). In the past 2 years she was the Director of Breast Cancer Translational Research Laboratory at Tel Aviv Sourasky Medical Center (Ichilov Hospital).

DR. EFRAT DVASH CTO

Company Information:

Offices and laboratory situated in Park Hamada, Rehovot, Israel

A team 20 employees 13 R&D researchers 8 Ph.D. in microbiology

ADVISORY BOARD

Professor Guy Bloch is one of the top research scientists from the Department of Ecology, Evolution, and Behavior (EEB) at The Hebrew University of Jerusalem. Professor Bloch's main research interests are the evolution and mechanisms underlying sociality and social behavior, using bees as a model system. Professor Guy Bloch has also years of experience working as a scientific advisor to Pollination Services Yad-Mordechai

PROF. GUY BLOCH ADVISOR

Prof. Yuval Shoham from the Department of Biotechnology and Food Engineering at the Technion institute. Received his Ph.D. in Biochemical Engineering from M.I.T. Served as the director of The Lorry I. Lokey Interdisciplinary Center for Life Sciences and Engineering, and as the President of the Israel Society for Microbiology.Professor Shoham's research focuses on the catalytic mechanisms and structure-function relationships of industrial enzymes. He was involved in several industrial projects, including the development of a large-scale process for bleaching paper pulp and an enzymatic process for making low calorie natural juices.

PROF. YUVAL SHOHAM ADVISOR

Prof. Menachem Rubinstein is a member of the Department of Molecular Genetics at the Weizmann Institute of Science. During his career, Prof. Rubinstein's research focused on questions with bio-chemical and molecular aspects, while using cutting edge technological and scientific techniques. His studies led to the development of three drugs used for autoimmune diseases, viral infections and cancer. Prof. Rubinstein has vast experience in protein expression, isolation and characterization. Many of his discoveries led to registration of patented inventions.

PROF. MENACHEM RUBINSTEIN ADVISOR

DECEMBER 2021

MARKET OPPORTUNITIES

HONEY MARKET SIZE

- The global honey market size was valued at USD 9.08 billion in 2019.
- Honey market size is expected to reach a of 17.2 billion USD in 2028.
- Expected compound annual growth rate (CAGR) of 8%.
High demand for nutritious food products (super food) such as honey, as part of maintaining a healthy lifestyle. + honey is becoming widely used in many applications: food & beverages, cosmetics and pharmaceuticals.

-

- World population growth.

The factor driving the market growth includes:

Source: The global honey market and Ukraine challenges and trends

DECEMBER 2021

WWW.BEE-IO.COM PAGE 9

2020 - HONEY WAS DECLARED THE MOST PREFERRED SWEETENER IN THE USA

	26%	31%
	23%	15%
11%		8%
9%		11%
9%		8%
9%		12%
		3%
		3%
		3%

Honey
Granulated sugar (or white sugar)
Brown sugar
Non-calorie sweeteners (like Splenda or Sweet N Low)
Maple Syrup
Stevia
Other sugar (like sugar in the raw or turbinado)	4%
Monk fruit	3%
Agave nectar	3%

Which of the following sweeteners is your favorite? (n= 2,000, Gen Pop)

Goodness Seekers (n= 350)

Source: The attitude & Usage Study NHB | 2020

THE U.S HONEY MARKET

- Honey is an excellent source of numerous nutritional ingredients including vitamins, minerals, calcium, and antioxidants.
- Honey has several medicinal properties and can help improve metabolic activities, maintain blood pressure levels, and can even heal burn wounds.
- Honey is widely used in many applications: food & beverages, cosmetics and pharmaceuticals.

Source: Grand View Research

The global production of honey, mn tonnes

THE GLOBAL PRODUCTION OF HONEY

- moving away from honey production to pollination services.
- Sensitivity of the Honeybee.
- Climate changes and rain absence in many places in the world.

Global Production of honey is limited and, in some countries, declining due to different factors:

Source: The global honey market and Ukraine challenges and trends, Food and Agriculture Organization (FAO) of the United | FAO Statistics Division 2020

DECEMBER 2021

OUR SOLUTION

BEE-IO - PURE HONEY WITHOUT A BEE

BEE-IO PROCESSING

Transforming the nectar into honey using Bee-io's innovative biosynthesis.

HONEY

Our honey is ready! With the same qualities and wonderful taste, we all know and love.

EVAPORATION

Removal of excess water, to reach the honey texture familiar to us.

FILTRATION

Cleaning our nectar from unwanted substances and residue leftover from the Extraction stage.

NECTAR PRODUCTION

Production of the sweetest nectar mother nature has to offer.

01

05

DECEMBER 2021

KEY PLAYERS MAP

100% mono- floral

Baby safe

Cost reduction

Year-round production and short production time

No toxins, no pesticides, and no antibiotics time

PURE HONEY	VEGAN HONEY SUBSTITUTES	BEE-IO HONEY

Sustainable, Bee-less

Honey varieties

Medical properties

Honey texture/flavors/aroma

Nutritional values

BEE-IO V S HONE Y M ARKET KE Y PL AYERS

*Currently, the company is yet to conduct medical research confirming the health benefits and nutritional values of its cultivated honey product.

2 patents pending (USPTO)

Flower nectar extraction

Turning nectar into honey

SEPTEMBER 2020

DECEMBER 2021

WWW.BEE-IO.COM PAGE 16

INTELLEC TUAL PROPERT Y

*The company has filed 4 provisional patent applications and currently has no registered patents.

COLL ABOR ATION WITH WORLD TOP RANKING INSTITUTES

- Optimizing and developing new cuttingedge technology for nectar production.
- Harnesses the innovation of Prof. Asaph Aharoni in plant sciences.

THE WEIZMANN INSTITUTE OF SCIENCE

Optimizing and developing new cutting-edge technology for cultured honey production.

MIT (MASSACHUSETTS INSTITUTE OF TECHNOLOGY)

Harnesses the innovation of Prof. Ron Weiss in synthetic biology.

HONEY PRODUCTION PROCESS TODAY

- This time-consuming process has not changed for decades.
- Highly sensitive process which depends on many unexpected changes.
- Pressure to use natural nectar substitutes.

DECEMBER 2021

MAIN CONCERNS

ECONOMICAL ENVIRONMENTAL ETHICAL

THREE INHERENT PROBLEMS:

- World consumption is increasing faster than production.
- Honeybee populations are declining due to climate change, parasites, contaminations and viruses.
- Honey is getting more expensive.

EACH BEEHIVE Can produce about 20 kgs of honey per year

Source: https://adventuresinbeeland.com/2019/01/14/how-many-honey-bees-are-there-a-2019-update/ https://www.honey.com/honey-industry/statistics/retail-honey-price (Data from Bee Culture magazine)

Average retail honey price per pound Across all reporting regions

ECONOMIC AL

DECEMBER 2021

Current honey manufacturing has led to:

- Less native pollinator
- The mysterious Colony Collapse Disorder (CCD)
- Increased vulnerability of honeybees
- Climate changes, desertification and rain absence in many places in the world, reduce the number of flowers and flowers nectar.

DECEMBER 2021

- Honeybees are bred and managed as factoryfarmed animals with poor conditions including stress in transportation, injuries and living in dense conditions.
- The large amount of managed bees has accelerated the reduction of many other bee species around the world.
- Humans choose to eliminate entire colonies by taking all their honey in cold seasons.