XTL Biopharmaceuticals Ltd.

Foreign Filer Report • Mar 31, 2022

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X T L BIOPHARMACEUTICALS LTD
Corporation no: 520039470	4313
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	Israel Securities Authority			Tel Aviv Stock Exchange		C001 ( Public )		Reported via MAGNA:	31/03/2022
	www.isa.gov.il			www.tase.co.il				Reference:	2022-02-039601	Time of broadcast: 00:23 00:23

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Report of Periodic or Interim ReportRegulation 3 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

	The corporation is a foreign private issuer as defined by U.S. Securities Laws.

Attached hereto is a report onAnnual Report - Form 20F 2021

f20f2021_xtlbiopharmaEDGAR_isa.pdf

Link to filing on foreign stock exchange (optional): _________

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
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Stock Exchange/Market: NASDAQ CM	Date of revision of form structure: 22/02/2022
Address: HaCharoshet st 5 , Ra'anana 43656   Israel , Tel: 09-9557080 , Fax: 09-9519708
E-mail address: ir@xtlbio.com   Company site: www.xtlbio.com
Previous names of reporting entity: XENOGRAFT TECHNOLOGIES LTD
Name of the Signatory: Kntor Ronen Position of Signatory in the reporting corporation: Attorney/Legal Counsel Name of Employer Company:
Address: abba hillel 12 , ramat gan 5250606 Telephone: 03-6133371 Facsimile: 03-6133372 E-mail: rkantor@dtkgc.com 1