OPKO Health Inc.

Proxy Solicitation & Information Statement • May 18, 2023

Schedule 14aRevised proxy card false

����� ���', ����	2 380
OPKO HEALTH, INC
Corporation no: 2279206	13156
- - -

	Israel Securities Authority			Tel Aviv Stock Exchange		C002 ( Public )		Reported via MAGNA:	17/05/2023
	www.isa.gov.il			www.tase.co.il				Reference:	2023-02-045358	Time of broadcast: 23:58 23:58

---

Immediate ReportRegulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

	The corporation is a foreign private issuer as defined by U.S. Securities Laws.

Attached hereto is a report onSchedule 14a Revised proxy card

20230517Sch14A_isa.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
- - -
Stock Exchange/Market: NASDAQ GSM	Date of revision of form structure: 02/05/2023
Address: Ashlegan 16 , Kiryat Gat 8211804   Israel , Tel: 08-9300051 , Fax: 08-9543101
E-mail address: gfaibish@opko.com   Company site: Www.Opko.Com
Previous names of reporting entity:
Name of the Signatory: Faibish Gabriel Position of Signatory in the reporting corporation: General Counsel Name of Employer Company:
Address: Ashlegan 16 , Kiryat Gat 8211804 Telephone: 08-9300051 Facsimile: 08-9543101 E-mail: gfaibish@opko.com 1