OPKO Health Inc.

Regulatory Filings • Jan 6, 2024

FORM 4
Check this box if no longer subject to
Section 16. Form 4 or
Form 5 obligations
may continue. See	UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Instruction 1(b).	Washington, D.C. 20549
Check this box to
indicate that a	STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
transaction was made pursuant to a contract,
instruction or written	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the
plan for the purchase	Investment Company Act of 1940
or sale of equity
securities of the issuer
that is intended to
satisfy the affirmative
defense conditions of
Rule 10b5-1(c). See
Instruction 10.

(Print or Type Responses)

1. Name and Address of Reporting Person * Richard C. Pfenniger, Jr.			2. Issuer Name and Ticker or Trading Symbol OPKO Health, Inc. [ OPK ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __ X __ Director _____ 10% Owner
(Last) OPKO Health, Inc. 4400 Biscayne Blvd.	(First) (Middle)		3. Date of Earliest Transaction (Month/Day/Year) 01/05/2024	_ Officer (give title below) ___ Other (specify below)
Miami, FL 33137	(Street)		4. If Amendment, Date Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) _ X _ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person
(City)	(State)	(Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security	2. Transaction	2A. Deemed	3. Transaction		4. Securities Acquired			5. Amount of Securities	6.	7. Nature
(Instr. 3)	Date	Execution Date, if	Code		(A) or Disposed of (D)			Beneficially Owned Following	Ownership	of Indirect
	(Month/Day/Year)	any	(Instr. 8)		(Instr. 3, 4 and 5)			Reported Transaction(s)	Form:	Beneficial
		(Month/Day/Year)						(Instr. 3 and 4)	Direct (D)	Ownership
						(A)			or Indirect	(Instr. 4)
						or			(I)
			Code	V	Amount	(D)	Price		(Instr. 4)

1/5/24, 12:15 PM					Ownership	Submission
	Common Stock	01/05/2024		P	13,000	A	\$ 0.9264	313,000	D
	Common Stock	01/05/2024		P	12,000	A	\$ 0.9488	325,000	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned

( e.g. , puts, calls, warrants, options, convertible securities)

1. Title of	2.	3. Transaction	3A. Deemed	4.		5. Number		6. Date Exercisable		7. Title and		8. Price of	9. Number of	10.	11. Nature
Derivative	Conversion	Date	Execution Date, if	Transaction		of		and Expiration Date		Amount of		Derivative	Derivative	Ownership	of Indirect
Security	or Exercise	(Month/Day/Year)	any	Code		Derivative		(Month/Day/Year)		Underlying		Security	Securities	Form of	Beneficial
(Instr. 3)	Price of		(Month/Day/Year)	(Instr. 8)		Securities				Securities		(Instr. 5)	Beneficially	Derivative	Ownership
	Derivative					Acquired					(Instr. 3 and 4)		Owned	Security:	(Instr. 4)
	Security					(A) or							Following	Direct (D)
						Disposed							Reported	or Indirect
						of (D)							Transaction(s)	(I)
						(Instr. 3, 4,							(Instr. 4)	(Instr. 4)
						and 5)
											Amount
								Date	Expiration		or
								Exercisable	Date	Title	Number
				Code	V	(A)	(D)				of Shares

Explanation of Responses:

Signatures

Steven D. Rubin, Attorney-in-Fact 01/05/2024

** Signature of Reporting Person Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

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