SAREUM HOLDINGS PLC

Director's Dealing • Nov 8, 2023

National Storage Mechanism | Additional information

RNS Number : 8299S

Sareum Holdings PLC

08 November 2023

Sareum Holdings PLC

("Sareum" or the "Company")

Director Dealings

Cambridge, UK, 8 November 2023 - Sareum Holdings plc (AIM: SAR), a biotechnology company developing next generation kinase inhibitors for autoimmune disease and cancer, announces the following share transactions carried out by Directors.

As announced on 2 November 2023, Dr Tim Mitchell, Chief Executive Officer, and Dr John Reader, Chief Scientific Officer, each exercised options over 95,040 ordinary shares of 1.25 pence each in the Company (the "Options Exercise"), at an exercise price of 30 pence per ordinary share.

Of those shares received pursuant to the Options Exercise, Dr Mitchell and Dr Reader have retained 23,040 and 44,614 ordinary shares, respectively, following the sale of 72,000 and 50,426 ordinary shares, respectively, at a price of 56.8 pence per ordinary share (the "Share Sales"). The Share Sales were undertaken partly in order to compensate for the cost and tax liabilities arising from the Options Exercise.

Following the Options Exercise and Share Sales, Dr Mitchell's and Dr Reader's resultant interests in the Company will be as follows: 

Director/ PDMR	Number of shares purchased pursuant to the Options Exercise	Number of shares sold pursuant to Sale Shares	Sale price	Resultant total number of ordinary shares held in the Company	Percentage of issued share capital
Tim Mitchell (1)	95,040	72,000	56.8p	1,032,561	1.47%
John Reader (2)	95,040	50,426	56.8p	1,077,111	1.53%

(1) - Included within Tim Mitchell's total holding are 200,000 ordinary shares held by his spouse.

(2) - Included withing John Reader's total holding are 66,666 ordinary shares held by his spouse.

For further information, please contact: 

Sareum Holdings plc Tim Mitchell, CEO Lauren Williams, Head of Investor Relations	01223 497700 ir@sareum.co.uk
Strand Hanson Limited (Nominated Adviser) James Dance / James Bellman	020 7409 3494
Peel Hunt LLP (Joint Corporate Broker) James Steel / Patrick Birkholm	020 7418 8900
Hybridan LLP (Joint Corporate Broker) Claire Noyce ICR Consilium (Financial PR) Jessica Hodgson / Davide Salvi / Stella Lempidaki	020 3764 2341 020 3709 5700

PDMR Notification Forms

The information set out below is provided in accordance with the requirements of Article 19(3) of the EU Market Abuse Regulation No 596/2014.

1.

Details of the person discharging managerial responsibilities / person closely associated

a)

Name

Tim Mitchell

2.

Reason for the Notification

a)

Position/status

Chief Executive Officer

b)

Initial notification/amendment

Initial notification

3.

Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor

a)

Name

SAREUM HOLDINGS PLC

b)

LEI

213800PKERN2DY8FFM72

4.

Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv)each place where transactions have been conducted

a)

Description of the Financial instrument, type of instrument

Ordinary shares of 1.25p each in the share capital of Sareum Holdings plc

Identification code

ISIN for Ordinary Shares: GB00B02RFS12

b)

Nature of the Transaction

Sale of ordinary shares

c)

Price(s) and volume(s)

Price(s)	Volume(s)
56.8p	72,000 sold

d)

Aggregated information

-      Aggregated volume

-      Price

Price(s)	Volume(s)
56.8p	72,000 sold

e)

Date of the transaction

7 November 2023

f)

Place of the transaction

London Stock Exchange (AIM)

1.

Details of the person discharging managerial responsibilities / person closely associated

a)

Name

John Reader

2.

Reason for the Notification

a)

Position/status

Chief Scientific Officer

b)

Initial notification/amendment

Initial notification

3.

Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor

a)

Name

SAREUM HOLDINGS PLC

b)

LEI

213800PKERN2DY8FFM72

4.

Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv)each place where transactions have been conducted

a)

Description of the Financial instrument, type of instrument

Ordinary shares of 0.025p each in the share capital of Sareum Holdings plc

Identification code

ISIN for Ordinary Shares: GB00B02RFS12

b)

Nature of the Transaction

Sale of ordinary shares

c)

Price(s) and volume(s)

Price(s)	Volume(s)
56.8p	50,426 sold

d)

Aggregated information

-      Aggregated volume

-      Price

Price(s)	Volume(s)
56.8p	50,426 sold

e)

Date of the transaction

7 November 2023

f)

Place of the transaction

London Stock Exchange (AIM)

About Sareum

Sareum Holdings (AIM:SAR) is a clinical-stage biotechnology company developing next generation kinase inhibitors for autoimmune disease and cancer.

The Company is focused on developing next generation small molecules which modify the activity of the JAK kinase family and have best-in-class potential. Its lead candidate, SDC-1801, simultaneously inhibits TYK2 and JAK1. SDC-1801 is a potential treatment for a range of autoimmune diseases and has entered Phase 1a/b clinical development with an initial focus on psoriasis.

Sareum has an economic interest in SRA737, a clinical-stage Chk1 inhibitor which it originally developed in collaboration with several Cancer Research UK-related organisations. SRA737 has shown promising safety and efficacy in two Phase 1/2 clinical trials.

Sareum is also developing SDC-1802, a TYK2/JAK1 inhibitor with a potential application for cancer immunotherapy.

Sareum Holdings plc is based in Cambridge, UK, and is listed on the AIM market of the London Stock Exchange, trading under the ticker SAR. For further information, please visit the Company's website at www.sareum.com

- Ends -

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