Oxford Biomedica PLC

Pre-Annual General Meeting Information • May 5, 2023

This document is important and requires your immediate attention.

If you are in any doubt as to the action to be taken, please consult an appropriately authorised financial adviser immediately. If you have sold or transferred all of your holding of ordinary shares in Oxford Biomedica plc ("Oxford Biomedica" or the "Company"), you should hand this document to the stockbroker, bank or other agent through or to whom the sale or transfer was effected for transmission to the purchaser or transferee.

Oxford Biomedica plc Notice of Annual General Meeting

Notice of the 2023 Annual General Meeting of the Company to be held at our offices at Windrush Court, Transport Way, Oxford OX4 6LT on 23 June 2023 at 3.00 p.m. is set out on pages 2 to 3 of this document

The Company's 2023 AGM will be held as a combined physical and electronic meeting.

Further information on the meeting arrangements are set out on page 6.

Shareholders are requested to complete and submit a Form of Proxy by electronic means via Signal Shares (www.signalshares.com) or via the LinkVote+ app or if you are an institutional investor, via Proxymity (https://www.proxymity.io) or via CREST (if your shares are held electronically). You will no longer automatically receive a proxy form, which will help reduce the Company's print and distribution costs along with the impact on the environment. Further details on how to submit your vote can be found in note 5 in the Notes for Shareholders.

Contents

1.	Letter from the Chair	Page 1
2.	Notice of 2023 Annual General Meeting	Page 2
3.	Explanation of business to be conducted at the Annual General Meeting	Page 4
4.	Shareholder guide	Page 6
5.	Notes for shareholders	Page 7
6.	Appendix 1: Directors' biographies	Page 9
7.	Appendix 2: KPMG LLP Statement of Reasons connected with ceasing
	to hold office as auditors	Page 10

5 May 2023

Dear Shareholder

2023 Annual General Meeting (AGM)

This document comprises the Notice of the 2023 AGM ("Notice") of Oxford Biomedica plc ("Oxford Biomedica" or the "Company"). A copy of the Notice and the Company's Annual report and accounts for the year ended 31 December 2022 can be viewed on our website (www.oxb.com).

The AGM is an important event in the Company's corporate calendar and provides an opportunity for the Company's Directors to engage with shareholders. In line with previous years, we are proposing to hold our 2023 AGM as a combined physical and electronic meeting with the proceedings of the meeting being available via audio.

If you wish to attend the meeting in person, please register your intention to do so as soon as practicable by email to ir@oxb.com.

Shareholders will be able to attend the meeting via the online meeting platform, which you can access by logging on to https://web.lumiagm.com. On this website, you can also ask questions and submit your votes during the meeting. A step-by-step guide on how to join the meeting electronically and ask questions and submit your votes can be found on page 6 of this document.

Your vote is important and the Company therefore requests that all of its shareholders (i) appoint the Chair of the meeting as their proxy and (ii) submit their votes via proxy in advance of the meeting, to ensure that their votes are counted. If a shareholder appoints a person other than the Chair of the meeting as their proxy, if for some reason that shareholder or that other proxy are not able to attend the 2023 AGM electronically or in person, that shareholder's votes will not be counted (further details on proxy voting can be found in note 5 in the Notes for Shareholders). Accordingly, those submitting a proxy appointment are strongly encouraged to appoint the Chair of the meeting rather than a named person as their proxy. This will ensure that your vote will be counted.

The Company understands that the AGM also serves as a forum to engage with shareholders and shareholders' views are always very important to us. Therefore, to support engagement, following the conclusion of the 2023 AGM, we will host a presentation via webcast which will be presented by Dr. Frank Mathias and Stuart Paynter, Chief Executive Officer  and  Chief Financial Officer. Afterwards, Dr. Mathias, Stuart Paynter, the other Directors and I will also answer questions from shareholders. Shareholders are encouraged to submit questions in advance by emailing ir@oxb.com before 2.30 p.m. BST on 23 June 2023. After responding to these pre-submitted questions, shareholders will be able to use the electronic meeting platform to ask further questions or pose questions in person. We may choose to summarise and bundle questions thematically or set further conditions to facilitate the smooth running of the webcast. If you wish to watch or participate in the webcast and subsequent Q&A session electronically, information on how to do that is set out on page 6.

The Resolutions put to you for voting will be generally familiar to you and are further explained in the explanation of business to be conducted at the 2023 AGM on pages 4 to 5. In total, there are nineteen Resolutions to be proposed at the 2023 AGM and the voting results will be notified to the London Stock Exchange as soon as possible following the conclusion of the meeting and posted on the Company's website. All Resolutions will be put to a poll. This will ensure an exact and definitive result.

Your Directors consider each Resolution to be in the best interests of the Company and its shareholders as a whole and unanimously recommend you vote in favour of each of them, as they intend to do in respect of their own beneficial shareholdings.

I would like to thank all shareholders for their ongoing support during 2022.

Yours sincerely

Dr. Roch Doliveux Chair Oxford Biomedica plc

Notice is hereby given that the 2023 Annual General Meeting ("AGM") of Oxford Biomedica plc (the Company") will be held at Windrush Court, Transport Way, Oxford OX4 6LT on 23 June 2023 at 3.00 p.m. to consider, and if thought fit, pass the following Resolutions.

The 2023 AGM will be held as a combined physical and electronic meeting.

Resolutions 1 to 16 (inclusive) will be proposed as Ordinary Resolutions and therefore each such Resolution must receive over 50% of the votes cast to be passed.

Resolutions 17 to 19 (inclusive) will be proposed as Special Resolutions and therefore each such Resolution must receive at least 75% of the votes cast in order to be passed.

Ordinary Resolutions

• 1. To receive and adopt the Company's Annual report and accounts (the "Annual Report") for the financial year ended 31 December 2022, the Directors' report, and the report of the independent auditors on those accounts.
• 1. To receive the Directors' Remuneration Report and the Report of the independent auditors on the auditable part of the Remuneration Report (excluding the Directors' Remuneration Policy) set out at pages 89 to 114 of the Annual Report for the financial year ended 31 December 2022.
• 1. To appoint Dr. Frank Mathias as a Director of the Company.
• 1. To appoint Leone Patterson as a Director of the Company.
• 1. To reappoint Dr. Roch Doliveux as a Director of the Company.
• 1. To reappoint Professor Dame Kay Davies as a Director of the Company.
• 1. To reappoint Stuart Paynter as a Director of the Company.
• 1. To reappoint Stuart Henderson as a Director of the Company.
• 1. To reappoint Dr. Heather Preston as a Director of the Company.
• 1. To reappoint Robert Ghenchev as a Director of the Company.
• 1. To reappoint Dr. Michael Hayden as a Director of the Company.
• 1. To reappoint Catherine Moukheibir as a Director of the Company.
• 1. To reappoint Namrata Patel as a Director of the Company.
• 1. To appoint PriceWaterhouseCoopers LLP as auditors of the Company from the conclusion of the meeting until the conclusion of the next AGM of the Company at which accounts are laid.
• 1. To authorise the Audit Committee for and on behalf of the Board to determine the auditor's remuneration.
• 1. That, in substitution for all existing general authorities, the Directors be, and are, generally and unconditionally authorised for the purposes of section 551 of the Companies Act 2006 (the "Act") to exercise all the powers of the Company to:
  2. (a) allot shares in the Company or to grant rights to subscribe for or to convert any security into shares in the Company up to an aggregate maximum nominal amount of £16,076,815;
  3. (b) allot further equity securities (within the meaning of section 560(1) of the Act) up to an aggregate maximum nominal amount of £16,076,815 in connection with a rights issue in favour of shareholders,

such authority to expire at the end of the next AGM of the Company following the passing of this Resolution or, if earlier, at the close of business on 23 September 2024 (unless previously revoked or varied by the Company in general meeting) but, in each case, prior to its expiry, revocation or variation the Company may make offers, and enter into agreements, which would, or might, require equity securities to be allotted (and treasury shares to be sold) after the authority expires, or is otherwise revoked or varied and the Board may allot equity securities (and sell treasury shares) under any such offer or agreement as if this authority had not expired or been revoked or varied.

For the purposes of this Resolution 16 "rights issue" means an offer to:

• (i) ordinary shareholders in proportion (as nearly as may be practicable) to their existing holdings; and
• (ii) holders of other equity securities, as required by the rights of those securities or, subject to such rights, as the Directors otherwise consider necessary,

to subscribe for further securities by means of the issue of a renounceable letter (or other negotiable document) which may be traded for a period before payment for the securities is due, including an offer to which the Directors may impose any limits or restrictions or make any other arrangements which they consider necessary or appropriate to deal with treasury shares, fractional entitlements, record dates, legal, regulatory or practical problems in, or under the laws of, any territory or any other matter.

Special Resolutions

• 1. That, subject to the passing of Resolution 16 and in substitution for all existing authorities, the Directors be, and are, generally and unconditionally authorised to allot equity securities (as defined in section 560 of the Act) for cash under the authority given by Resolution 16 and/or to sell ordinary shares held by the Company as treasury shares for cash as if section 561 of the Act did not apply to any such allotment or sale, such authority to be limited:
  2. (a) to the allotment of equity securities and/or sale of treasury shares for cash in connection with an offer of, or an invitation to apply for, equity securities (but in the case of an allotment pursuant to the authority granted by paragraph (b) of Resolution 16, by way of rights issue only):
• (i) to ordinary shareholders in proportion (as nearly as practicable) to the respective number of ordinary shares held by such holders; and
• (ii) to holders of other equity securities, as required by the rights of those securities or, subject to such rights, as the Directors otherwise consider necessary,

and so that the Directors may impose any limits or restrictions or make any other arrangements which they consider necessary or appropriate to deal with treasury shares, fractional entitlements, record dates, or legal, regulatory or practical problems arising in, or pursuant to, the laws of any territory or the requirements of any regulatory body or stock exchange in any territory, or any other matter;

• (b) to the allotment of equity securities or sale of treasury shares (otherwise than pursuant to paragraph (a) of this Resolution 17) up to an aggregate maximum nominal amount of £4,823,044; and
• (c) to the allotment of equity securities or sale of treasury shares (otherwise than under paragraph (a) or paragraph (b) of this Resolution 17) up to a nominal amount equal to 20% of any allotment of equity securities or sale of treasury shares from time to time under paragraph (b) of this Resolution 17, such authority to be used only for the purposes of making a followon offer which the Board of the Company determines to be of a kind contemplated by paragraph 3 of Section 2B of the Statement of Principles on Disapplying Pre-Emption Rights most recently published by the Pre-Emption Group prior to the date of this Notice,

such authority to expire at the end of the next AGM of the Company following the passing of this Resolution 17 or, if earlier, at the close of business on 23 September 2024 (unless previously revoked or varied by the Company in general meeting) but, in each case, prior to its expiry, revocation or variation the Company may make offers, and enter into agreements, which would, or might, require equity securities to be allotted (and treasury shares to be sold) after the authority expires, or is otherwise revoked or varied and the Directors may allot equity securities (and sell treasury shares) under any such offer or agreement as if this authority had not expired or been revoked or varied.

For the purpose of this Resolution 17, "rights issue" has the same meaning as in Resolution 16 above.

• 1. That subject to the passing of Resolution 16 and in substitution for all existing authorities (other than the authority granted under Resolution 17), the Directors be, and are, generally and unconditionally authorised (in addition to any authority granted under Resolution 17) to allot equity securities (as defined in section 560 of the Act) for cash under the authority given by Resolution 16 and/or to sell ordinary shares held by the Company as treasury shares for cash as if section 561 of the Act did not apply to any such allotment or sale, such authority to be:
  2. (a) limited to the allotment of equity securities or sale of treasury shares up to an aggregate maximum nominal amount of £4,823,044, such authority to be used only for the purposes of financing (or refinancing, if the authority is to be used within twelve months after the original transaction) a transaction which the Directors determine to be an acquisition or other capital investment of a kind contemplated by the Statement of Principles on Disapplying Pre-Emption Rights most recently published by the Pre-Emption Group prior to the date of this Notice; and
  3. (b) limited to the allotment of equity securities or sale of treasury shares (otherwise than under paragraph (a) of this Resolution 18) up to a nominal amount equal to 20% of any allotment of equity securities or sale of treasury shares from time to time under paragraph (a) of this Resolution 18, such authority to be used only for the purposes of making a follow-on offer which the Board of the Company determines to be of a kind contemplated by paragraph 3 of Section 2B of the Statement of Principles on Disapplying Pre-Emption Rights most recently published by the Pre-Emption Group prior to the date of this Notice,

such authority to expire at the end of the next AGM of the Company following the passing of this Resolution 18 or, if earlier, at the close of business on 23 September 2024 (unless previously revoked or varied by the Company in general meeting) but, in each case, prior to its expiry, revocation or variation the Company may make offers, and enter into agreements, which would, or might, require equity securities to be allotted (and treasury shares to be sold) after the authority expires, or is otherwise revoked or varied and the Directors may allot equity securities (and sell treasury shares) under any such offer or agreement as if this authority had not expired or been revoked or varied.

1. That in accordance with the Company's articles of association ("Articles"), a general meeting (other than an Annual General Meeting) may be held on not less than 14 clear days' notice.

By order of the Board

Natalie Walter General Counsel and Company Secretary Oxford Biomedica plc

5 May 2023

The notes on the following pages give an explanation of the proposed Resolutions.

Resolutions 1 to 16 (inclusive) are proposed as Ordinary Resolutions. This means that for each of those Resolutions to be passed, more than half of the votes cast (more than 50%) must be in favour of the Resolution. Resolutions 17 to 19 (inclusive) are proposed as Special Resolutions. This means that for each of those Resolutions to be passed, at least three- quarters of the votes cast (at least 75%) must be in favour of the Resolution.

The Directors consider that all the Resolutions to be put to the meeting are in the best interests of the Company and its shareholders as a whole. The Board unanimously recommends that you vote in favour of all the Resolutions, as they propose to do in respect of their own beneficial holdings of ordinary shares in the issued share capital of the Company

Ordinary Resolutions

Resolution 1 – Report and Accounts

The Company is required to present to the shareholders at the 2023 AGM the audited financial statements of the Company for the financial year ended 31 December 2022. This provides an opportunity to discuss the performance of the Company during the period, its management and its prospects for the future.

A copy of the Annual Report and accounts of the Company for the financial year ended 31 December 2022 is enclosed with this Notice of Meeting, or has been made available to you electronically on the Company's website at www.oxb.com.

Resolution 2 – Directors' Remuneration Report

Resolution 2 relates to the Company's Directors' Remuneration Report. The Directors' Remuneration Report sets out remuneration arrangements for, and payments made to, Directors in respect of 2022. The remuneration report appears at pages 89 to 114 of the Annual Report and accounts.

This Resolution is an advisory vote and the Directors' entitlements to remuneration are not conditional upon it.

Resolutions 3 to 13 – appointment and reappointment of Directors

The Articles require that any Director who was appointed after the last AGM or has served for three years, and one third of the other Directors, retire from office by rotation at each AGM. However, to ensure that the Company complies with the revised UK Corporate Governance Code, produced by the Financial Reporting Council in July 2018, all Directors will be subject to annual re-election.

At this year's AGM, Dr. Frank Mathias, who was appointed as Chief Executive Officer and a new Director to the Board in March 2023 and Leone Patterson, who was appointed as a Non-Executive Director to the Board in April 2023 will each stand for appointment by the shareholders for the first time.

Dr. Siyamak Rasty is retiring from the Board and therefore is not standing for re-election at the 2023 AGM.

The performance of all Directors proposed for reappointment has been evaluated by the Chair and the Board and it has been determined that they each perform effectively and show full commitment to their roles on the Board. The Board therefore recommends that you support the appointment of Dr. Mathias and Leone Patterson and the reappointment of each of the retiring Directors who are standing for reappointment.

Biographical details of each of the Directors can be found in Appendix 1 to this Notice.

Resolutions 14 and 15 – Appointment and remuneration of auditor

As required under the Companies Act 2006 ("Act"), Resolution 14 seeks shareholder approval for the appointment of PriceWaterhouseCoopers LLP as the Company's auditor. Having completed a competiive tender process in 2022, the Company's Audit Committee recommended to the Board that PriceWaterhouseCoopers LLP be appointed as the Company's auditor, subject to shareholder approval, in place of KPMG LLP who have completed their audit. KPMG LLP did not praticipate in the tender process. In accordance with the Act, KPMG LLP as the Company's outgoing auditor, is required to provide the Company with a statement of reasons, which outlines the circumstances relevant to it ceasing to hold office as auditor. A copy of KPMG LLP's statement of reasons is contained in Appendix 2 to this Notice.

Resolution 15 proposes that the Audit Committee be authorised for and on behalf of the Board to determine the auditor's remuneration.

Resolution 16 – authority to allot shares

Resolution 16 seeks shareholder approval to renew the Directors' authority to allot shares.

Under section 551 of the Act, the Directors cannot allot shares in the Company unless they are authorised to do so by the Company in general meeting. Resolution 16 is proposed as an Ordinary Resolution to seek a new authority, which will replace any existing authorities granted prior to the 2023 AGM. It is proposed that the Directors be authorised to allot new shares or to grant rights to subscribe for or to convert any security into shares in the Company, subject to the normal pre-emption rights reserved to shareholders contained in the Act, up to an aggregate maximum nominal amount of £16,076,815, representing approximately one-third of the issued share capital of the Company as at 2 May 2023, being the last practicable date before the publication of this Notice.

In line with The Investment Association ("IA") guidelines, the authority will also permit the Directors to allot an additional one third of the Company's issued share capital provided such shares are reserved for a fully preemptive rights issue. Resolution 16 reflects the IA's recommendations.

If the Directors wish to use the authority conferred in Resolution 16 to allot shares for cash, section 561(1) of the Act requires that the new shares must be offered first to existing shareholders in proportion to their existing shareholdings. The shareholders' entitlement to be offered the new shares is known as a "pre-emption right". However, for legal, regulatory and practical reasons, it might not be possible for new shares allotted by means of a rights issue to be issued to certain shareholders, particularly those resident overseas. Further, it might, in some circumstances, be in the Company's interests for the Directors to be able to allot some shares for cash without having to offer them first to existing shareholders. To enable this to be done, shareholders must first waive these pre-emption rights.

Special Resolutions

Resolutions 17 and 18 – disapplication of pre-emption rights

Resolutions 17 and 18 are proposed as Special Resolutions to seek new authorities, which will replace existing authorities granted prior to the 2023 AGM. If granted, the authorities set out in Resolutions 17 and 18 will enable the Directors to allot new shares without first offering them to existing shareholders in proportion to their existing holdings and without further reference to shareholders.

In November 2022, the Pre-Emption Group revised their Statement of Principles ("Revised Statement of Principles") to allow companies to seek authority for an issue of shares for cash otherwise than in connection with a pre-emptive offer to include: (i) an authority up to 10% of the Company's issued share cpaital for use on an unrestricted basis (plus an additional authority of up to 2% of the Company's issued share capital (excluding treasury shares) which may be sought solely for the purpose of making a follow-on offer of the kind contemplated by paragraph 3 of Section 2B of the Revised Statement of Principles); and (ii) an additional authority up to a further 10% of the Company's issued share capital for use in connection with an acquisition of specified capital investment announced contemporaneously with the issue, or that has taken place in the 12-month period preceeding the announcment of the issue (plus an additional authority of up to 2% of the Company's issued share capital (excluding treasury shares) which may be sought solely for the purpose of making a follow-on offer of the kind contemplated by paragraph 3 of Section 2B of the Revised Statement of Principles).

The Board, having considered the Revised Statement of Principles, has concluded that it would be in the best interest of the Company's shareholders to seek approval under the new regime. Accordingly, Resolutions 17 and 18 apply the increased limits of 10% of the Company's issued share capital (plus a further 2% of the Company's issued share capital to be used only for the purposes of making a follow-on offer) set out in the Revised Statement of Principles, and the Directors confirm their intention to adhere to the provisions in the Revised Statement of Principles (including the conditions specified in Part 2B of the Revised Statement of Principles).

Resolution 17 seeks the disapplication of pre-emption rights as follows:

• sub-paragraph (a) of Resolution 17 seeks authority for the Directors to allot new shares for cash by way of a pre-emptive offer or rights issue and to make any arrangements which may be necessary to deal with any legal, regulatory and practical problems arising from a rights issue or other pre-emptive offer, for example, by excluding affected shareholders from the rights issue or other pre-emptive offer;
• sub-paragraph (b) of Resolution 17 seeks authority to issue new shares (otherwise than under paragraph (a) of Resolution 17) up to a maximum aggregate nominal value of £4,823,044, equivalent to 10% of the Company's issued ordinary share capital as at 2 May 2023, being the last practicable date before the publication of this Notice; and
• sub-paragraph (c) of Resolution 17 seeks authority to limit the allotment of equity securities or sale of treasury shares (otherwise than under paragraphs (a) or (b) of Resolution 17) up to a maximum aggregate nominal value of £964,608 equal to 20% of any allotment of equity securities or sale of treasury shares from time to time under paragraph (b) of Resolution 17 (being 2% of the Company's issued share capital), to be used only for the purposes of making a follow-on offer which the Board of the Company determines to be of a kind contemplated by paragraph 3 of Section 2B of the Revised Statement of Principles.

Resolution 18 seeks the further disapplication of pre-emption rights as follows:

• sub-paragraph (a) of Resolution 18 seeks authority to issue new shares up to a further maximum aggregate nominal value of £4,823,044, equivalent to 10% of the Company's issued ordinary share capital as at 2 May 2023, being the last practicable date before the publication of this Notice, in connection with an acquisition or specified capital investment of a kind contemplated by the Revised Statement of Principles; and
• sub-paragraph (b) of Resolution 18 seeks authority to limit the allotment of equity securities or sale of treasury shares up to a maximum aggregate nominal value of £964,608 equal to 20% of any allotment of equity securities or sale of treasury shares from time to time, under paragraph (a) of Resolution 18 (being 2% of the Company's issued share capital), to be used only for the purposes of making a follow-on offer of the kind contemplated by paragraph 3 of Section 2B of the Revised Statement of Principles), to be used only in connection with an acquisition or specified capital investment.

It is the Company's intention that such authority would only be used in connection with an acquisition or a specified capital investment which the Company would announce at the same time as it announces the issue of shares in reliance on such authority, or which has taken place in the preceding 12 month period and is disclosed in the announcement of the issue of the shares.

However, the interests of existing shareholders are protected in that their proportionate interests in the Company cannot be reduced by more than 10% per cent through the issue of new shares for cash and cannot be reduced by more than a further 10% through the issue of new shares for cash in connection with an acquisition or a specified capital investment, plus a further 4% of the Company's issued share capital (excluding treasury shares) pursuant to follow-on offers of the kind contemplated by paragraph 3 of Section 2B of the Revised Statement of Principles. The Directors confirm that the authority granted by Resolution 18 will only be used in accordance with the Revised Statement of Principles.

The proposed authorities, if granted, will expire at the conclusion of the 2024 AGM or, if earlier, fifteen months from the date of the passing of the Resolutions. It is the Directors' intention to renew these authorities annually.

Resolution 19 – notice of general meetings

Resolution 19 is proposed to approve the holding of general meetings, other than AGMs, on 14 clear days' notice in accordance with the Companies (Shareholder Rights) Regulations 2009 (the "Regulations"). The authority will be effective until the 2024 AGM, when it is intended that the approval be renewed again. The Company will also need to meet the requirements for electronic voting under the Regulations before it can call a general meeting on 14 clear days' notice. If passed, this Resolution will enable the Company to retain maximum flexibility to seek shareholder approval for any future change or transaction more quickly, where it is thought by the Directors to be an advantage to the shareholders as a whole to do so.

Form of Proxy

You will no longer automatically receive a proxy form which will help reduce the Company's print and distribution costs along with the impact on the environment, however you are encouraged to submit your vote electronically via Signal Shares (www.signalshares.com) or via the LinkVote+ app or if you are an institutional investor, via Proxymity (https://www.proxymity.io) or via CREST (if your shares are held electronically). Proxy forms are available upon request from the Company's Registrar, Link Group (further details on how to submit your vote can be found in note 5 of the Notes for shareholders). Shareholders are advised to submit a proxy instruction in accordance with the instructions so as to ensure it arrives at the Company's registrars, Link Group, PXS 1, Central Square, 29 Wellington Street, Leeds, LS1 4DL or to submit a proxy vote electronically via www.signalshares.com, or the LinkVote+ app or if you are an institutional investor, via Proxymity (https://www.proxymity.io) (see note 5 of the Notes for Shareholders), as soon as possible, but in any event no later than 3.00 p.m. on 21 June 2023. The return of a Proxy form or the electronic appointment of a proxy does not preclude you from attending and voting at the 2023 AGM if you so wish. However, for the reasons given in the letter from the Chair that accompanies this Notice, shareholders are encouraged to attend the 2023 AGM virtually, via electronic means.

The Directors consider that the Resolutions to be proposed at the 2023 AGM are in the best interests of the Company and its shareholders, and they recommend shareholders to vote in favour of the Resolutions.

https://web.lumiagm.com Meeting ID: 192-070-889

Meeting Access

Shareholders can participate in the 2023 AGM electronically, should they wish to do so. This can be done by accessing the meeting website: https:// web.lumiagm.com

Lumi is available as a mobile web client, compatible with the latest browser versions of Chrome, Firefox, Edge and Safari and can be accessed using any web browser, on a PC, tablet or smartphone device.

On accessing the meeting website, you will be asked to enter the Meeting ID above.

You will then be prompted to enter your unique 11 digit Investor Code (IVC) including any leading zeros, and 'PIN'. Your PIN is the last 4 digits of your IVC. This will authenticate you as a shareholder.

Your IVC can be found on your share certificate, or Signal Shares users (www.signalshares.com) will find this under 'Manage your account' when logged in to the Signal Shares portal. You can also obtain this by contacting Link Group, our Registrars, by calling +44 (0) 371 277 1020*

Access to the meeting will be available from 3:00 pm on 23 June 2023; however, please note that your ability to vote will not be enabled until the Chair formally declares the poll open.

Broadcast

The meeting will be broadcast in audio format. Once logged in, and at the commencement of the meeting, you will be able to listen to and watch the proceedings of the meeting on your device.

Voting

Once the Chair has formally opened the meeting, the voting procedure will be explained. Once voting has opened, the voting icon will appear on the navigation bar. From here, the resolutions and voting choices will be displayed.

Select the option that corresponds with how you wish to vote. Once you have selected your choice, the option will change colour and a confirmation message will appear to indicate your vote has been cast and received. There is no submit button. If you make a mistake or wish to change your vote, simply select the correct choice. If you wish to "cancel" your vote, select the "cancel" button. You will be able to do this at any time whilst the poll remains open and before the Chair announces its closure.

Questions

hareholders are encouraged to ask questions in advance by emailing ir@oxb.com before 2.30 p.m. BST on 23 June 2023 and these will be addressed in the Q&A session during the webcast made available at 3:00 p.m. BST on 23 June 2023, which will follow the conclusion of (but does not form part of) the 2023 AGM.

Shareholders attending electronically may ask questions on the day through the Lumi platform, by typing and submitting their question in writing via the Lumi messaging function or verbally via the teleconference. To submit your question in writing select the messaging icon from within the navigation bar and type your question at the top of the screen, then click on the arrow icon to the right of the text box.

Details of how to access the teleconference will be provided on the day of the 2023 AGM once you are logged into the Lumi platform.

Requirements

An active internet connection is required at all times in order to allow you to cast your vote when the poll opens, submit questions and listen to the audiocast. It is the user's responsibility to ensure you remain connected for the duration of the meeting.

Duly appointed proxies and corporate representatives

If you wish to appoint a proxy other than the Chair of the meeting and for them to attend the virtual meeting on your behalf, please submit your proxy appointment in the usual way before contacting Link Group on +44 (0) 371 277 1020* in order to obtain their IVC and PIN. It is suggested that you do this as soon as possible and at least 48 hours (excluding non- business days) before the meeting.

If your shares are held within a nominee and you wish to attend the electronic meeting, you will need to contact your nominee as soon as possible. Your nominee will need to present a corporate letter of representation to Link Group, our registrar, as soon as possible and at least 72 hours (excluding non-business days) before the meeting, in order that they can obtain for you your unique IVC and PIN to enable you to attend the electronic meeting.

* Lines are open from 9.00 a.m. to 5.30 p.m. Monday to Friday, calls are charged at the standard geographic rate and will vary by provider. Calls outside the UK will be charged at the applicable international rate.

1. In line with previous years, the Company's 2023 AGM will be held as a combined physical and electronic meeting.

Shareholders not attending in person will be able to attend the meeting via the online meeting platform. (A step-by-step guide on how to access the online meeting platform can be found on page 6 of this document.) To ensure their votes are counted, the Company strongly encourages all shareholders to submit a proxy vote in advance of the meeting, appointing the Chair of the meeting as their proxy rather than a named person. If a named person is appointed, and for some reason that shareholder or that other proxy are not able to attend the 2023 AGM electronically or in person, that shareholder's votes will not be counted. These notes to the notice of meeting should be read in this context.

• 1. A shareholder entitled to attend and vote at the meeting is also entitled to appoint one or more proxies to attend, speak and vote on a show of hands and on a poll instead of him or her. As explained in note 1 above, shareholders submitting a form of proxy are strongly encouraged to appoint the Chair of the meeting rather than a named person as their proxy. This will ensure that your vote will be counted.
• 1. A proxy need not be a member of the Company. Where a shareholder appoints more than one proxy, each proxy must be appointed in respect of different shares comprised in his or her shareholding which must be identified on the proxy form. Each such proxy will have the right to vote on a poll in respect of the number of votes attaching to the number of shares in respect of which the proxy has been appointed. Where more than one joint shareholder purports to appoint a proxy in respect of the same shares, only the appointment by the most senior shareholder will be accepted as determined by the order in which their names appear in the Company's register of members. If you wish your proxy to speak at the meeting, you should appoint a proxy other than the Chair of the meeting and give your instructions to that proxy. If you are not a shareholder but you have been nominated by a shareholder to enjoy information rights, you do not have the right to appoint a proxy or proxies pursuant to note 2. Please read note 10.
• 1. A corporation which is a shareholder may appoint one or more corporate representatives who have one vote each on a show of hands and otherwise may exercise on behalf of other shareholders all of its powers as a shareholder provided that they do not do so in different ways in respect of the same shares.
• 1. You can vote using one of the following:
  2. by logging on to www.signalshares.com and following the instructions;
  3. Link Group, the company's registrar, has launched a shareholder app: LinkVote+. It's free to download and use and gives shareholders the ability to access their shareholding record at any time and allows users to submit a proxy appointment quickly and easily online rather than through the post. The app is available to download on both the Apple App Store and Google Play, or by scanning the relevant QR code below.

• if you are an institutional investor you may also be able to appoint a proxy electronically via the Proxymity platform, a process which has been agreed by the Company and approved by the Registrar. For further information regarding Proxymity, please go to www.proxymity.io. Your proxy must be lodged by 3.00 p.m. on 21 June 2023 in order to be considered valid or, if the meeting is adjourned, by the time which is 48 hours before the time of the adjourned meeting. Before you can appoint a proxy via this process you will need to have agreed to Proxymity's associated terms and conditions. It is important that you read these carefully as you will be bound by them and they will govern the electronic appointment of your proxy. An electronic proxy appointment via the Proxymity platform may be revoked completely by sending an authenticated message via the platform instructing the removal of your proxy vote.
• in the case of CREST members, by utilising the CREST electronic proxy appointment service in accordance with the procedures set out below.

If you need help with voting online, or require a paper proxy form, please contact the Company's Registrar, Link Group, by email at shareholderenquiries@linkgroup.co.uk., or by phone on 0371 664 0391 if calling from the United Kingdom, or +44 (0) 371 664 0391 if calling from outside of the United Kingdom. Calls will be charged at the standard geographic rate and will vary by provider. Calls outside the United Kingdom will be charged at the applicable international rate. The lines are open between 9.00 a.m.–5.30 p.m., Monday to Friday, excluding public holidays in England and Wales.

In order for a proxy appointment to be valid a proxy instruction must be completed. In each case the proxy instruction must be received by Link Group, PXS 1, Central Square, 29 Wellington Street, Leeds, LS1 4DL by 3:00 p.m. on 21 June 2023. Shareholders who intend to appoint more than one proxy can obtain additional forms of proxy from Link Group.

To register your vote electronically via Signal Shares (www. signalshares.com), select "Register an Account" then enter your surname, Investor Code, Postcode and an email address. Create a password and click "Register" to proceed. You will be able to vote immediately by selecting "Proxy Voting" from the menu. You can find your Investor Code ("IVC") on your share certificate, or Signal Shares users (www.signalshares.com) will find this under 'Manage your account' when logged in to the Signal Shares portal. You can also obtain this by contacting Link Group, the Company's registrar, by calling +44 (0) 371 277 1020. Lines are open from 9.00 a.m. to 5.30 p.m. Monday to Friday. Calls are charged at the standard geographic rate and will vary by provider. Calls outside the UK will be charged at the applicable international rate.

• 1. An abstention (or "vote withheld") option has been included on the Form of Proxy and in the available options for electronic proxy voting. The legal effect of choosing the abstention option on any Resolution is that the shareholder concerned will be treated as not having voted on the relevant Resolution. The number of votes in respect of which there are abstentions will however be counted and recorded, but disregarded in calculating the number of votes for or against each Resolution.
• 1. In accordance with Regulation 41 of the Uncertificated Securities Regulations 2001 and section 360B(2) of the Act , the Company specifies that only those shareholders registered in the register of members of the Company as at close of business 21 June 2023 or, in the event that the meeting is adjourned, in such register not later than 48 hours before the time of the adjourned meeting (excluding any part of a day that is not a working day), shall be entitled to attend, or vote (whether in person or by proxy) at the meeting in respect of the number of shares registered in their names at the relevant time. Changes after the relevant time will be disregarded in determining the rights of any person to attend or vote at the meeting or any adjourned meeting (as the case may be).
• 1. CREST members who wish to appoint a proxy or proxies by utilising the CREST electronic proxy appointment service may do so by utilising the procedures described in the CREST Manual. CREST personal members or other CREST sponsored members, and those CREST members who have appointed a voting service

provider(s), should refer to their CREST sponsor or voting service provider(s), who will be able to take the appropriate action on their behalf. In order for a proxy appointment by means of CREST to be valid, the appropriate CREST message (a CREST Proxy Instruction) must be properly authenticated in accordance with Euroclear UK & International Limited ("EUI") specification and must contain the information required for such instructions, as described in the CREST Manual. The message must be transmitted so as to be received by the Registrar (ID RA10) by 3.00 p.m. 21 June 2023. For this purpose, the time of receipt will be taken to be the time (as determined by the timestamp applied to the message by the CREST applications host) from which the Registrar is able to retrieve the message by enquiry to CREST in the manner prescribed by CREST. CREST members and, where applicable, their CREST sponsors or voting service providers, should note that EUI does not make available special procedures in CREST for any particular messages. Normal system timings and limitations will therefore apply in relation to the input of CREST Proxy Instructions. It is the responsibility of the CREST members concerned to take (or, if the CREST member is a CREST personal member or sponsored member or has appointed a voting service provider(s), to procure that his CREST sponsor or voting service provider(s) take(s)) such action as shall be necessary to ensure that a message is transmitted by means of the CREST system by any particular time. In this connection, CREST members and where applicable, their CREST sponsors or voting service providers are referred, in particular, to those sections of the CREST Manual concerning practical limitations of the CREST system and timings. The Company may treat as invalid a CREST proxy instruction in the circumstances set out in Regulation 35(5)(a) of the Uncertificated Securities Regulations 2001.

• 1. Unless otherwise indicated on the Form of Proxy, CREST voting or any other electronic voting channel instruction, the proxy will vote as they think fit or, at their discretion, withhold from voting.
• 1. Completion of a proxy instruction will not affect the right of such member to attend and vote in person at the meeting or any adjournment thereof.
• 1. If you are a person who has been nominated under section 146 of the Act to enjoy information rights, you may have a right, under an agreement between you and the shareholder who has nominated you, to be appointed or to have someone else appointed for you as a proxy for the meeting. If you do not have such a right, or you do have such a right but do not wish to exercise it, you may have a right under such an agreement to give instructions to the shareholder who nominated you as to the exercise of the voting rights attached to the ordinary shares in respect of which you have been nominated.
• 1. As at 2 May 2023, being the last practicable date before the publication of this Notice, the Company's issued share capital consisted of 96,460,891 ordinary shares of 50 pence each, carrying one vote each, so that the total number of votes at such date is 96,460,891.
• 1. Voting on the Resolutions will be conducted by way of a poll. This will ensure an exact and definitive result.
• 1. Under section 527 of the Act, the Company may be required by shareholders representing at least 5% of the total voting rights of all shareholders who have the right to vote at the meeting (excluding votes which attach to treasury shares) or by at least 100 shareholders who have the right to vote at the meeting and hold shares in the Company on which there has been paid up an average sum, per shareholder, of at least £100, to publish on a website a statement setting out any matter relating to: (i) the audit of the Company's accounts that are to be laid before this AGM (including the independent auditors' report and the conduct of the audit) or (ii) any circumstance connected with the auditors to the Company ceasing to hold office since the previous meeting at which annual accounts and reports were laid in accordance with section 437 of the Act which, in either case, the requesting members propose to raise at the meeting. Such a request may be in hard copy or in electronic form, must identify the statement to which it relates, must be authenticated by the person or persons making it and must be received by the Company at least one week before the meeting.

Such requests should be sent to the Company at Windrush Court, Transport Way, Oxford, OX4 6LT or may be faxed to 01865 783001 or emailed to enquiries@oxb.com. The Company may not require the shareholders requesting such website publication to pay its expenses in complying with the section. Where the Company is required to place a statement on a website, it must forward the statement to the Company's auditors not later than the time when it makes the statement available on the website. The business which may be dealt with at this AGM includes any statement that the Company has been required to publish on a website.

• 1. A copy of this Notice, together with any members' statements which, in each case, have been received by the Company after the despatch of this Notice and the other information required by section 311A of the Act are all available on the Company's website at www.oxb.com under 'investors: shareholder meetings'.
• 1. Shareholders, proxies and authorised representatives will be required to provide their names and addresses for verification against the register of members and proxy appointments received by the Company before entering the meeting. Each authorised representative must produce proof of his or her appointment, in the form of the actual appointment or a certified copy. Other than this, there are no procedures with which any such persons must comply in order to attend and vote at the meeting.
• 1. In normal circumstances, shareholders, proxies and authorised representatives may raise questions at the meeting concerning any business being dealt with at the meeting and will receive answers, except that a question need not be answered where it would interfere unduly with the conduct of the meeting, would involve the disclosure of confidential information, where the answer has already been given on a website in the form of an answer to a question or where it is undesirable in the interests of the Company or the good order of the meeting that the question be answered. Shareholders are encouraged to submit questions in advance by emailing ir@oxb. com before 2.30 p.m. BST on 23 June 2023.
• 1. As explained in note 1 above the 2023 AGM will be held as a combined physical and electronic meeting. For shareholders attending the meeting remotely via the online meeting platform, access to the 2023 AGM will be available from 15 minutes before the meeting start time, although the voting functionality will not be enabled until the Chair of the meeting declares the poll open. During the AGM, you must ensure you are connected to the internet at all times in order to vote when the Chair commences polling on the Resolutions. Therefore, it is your responsibility to ensure connectivity for the duration of the AGM via your wifi. A user guide to the audio/video webcast is available on the Company's website at: www.oxb.com.
• 1. If you wish to appoint a proxy other than the Chair of the meeting and for them to attend the virtual meeting on your behalf, please submit your proxy appointment in the usual way before contacting Link Group on +44 (0) 371 277 1020 in order to obtain their IVC and PIN. It is suggested that you do this as soon as possible and at least 48 hours (excluding non-business days) before the meeting.
• 1. If your shares are held within a nominee and you wish to attend the electronic meeting, you will need to contact your nominee as soon as possible. Your nominee will need to present a corporate letter of representation to Link Group, the Company's registrar, as soon as possible and at least 72 hours (excluding non-business days) before the meeting, in order that they can obtain for you your unique IVC and PIN to enable you to attend the electronic meeting.
• 1. The following documents will be available for inspection at the registered office of the Company at Windrush Court, Transport Way, Oxford, OX4 6LT during normal business hours on any week day (public holidays excepted) from the date of this Notice until the date of the 2023 AGM, and at the place of the meeting for one hour before the meeting and at the meeting itself:
  2. copies of the Directors' service agreements and letters of appointment; and
  3. the constitutional documents of the Company, comprising the Articles.

Dr. Roch Doliveux

Chair

Dr. Roch Doliveux was appointed to the Board as Non-Executive Chair in June 2020. Dr. Doliveux also became Interim Chief Executive Officer from January 2022 until March 2023, following the Company's announcement of John Dawson's intention to retire as Chief Executive Officer and the acquisition of the AAV business in the US.

Dr. Doliveux is currently Chair of the Board of Directors at Pierre Fabre S.A. and Vice Chair of Pierre Fabre Participations. He was previously the Chief Executive Officer of UCB S.A. for ten years during which time he transformed the company from a diversified chemical group into a global biopharmaceutical leader. He was a member of the Board of UCB from 2002 – 2015 and from 2017 – 2021. In addition, Dr. Doliveux was a member of the Board of Stryker from 2010 – 2020 and Chair of the Compensation Committee from 2016 – 2020. He also chaired the Board of Vlerick Business School from 2013 – 2017, the Board of IMI, the largest healthcare publicprivate partnership in the world from 2012 – 2015 and GLG Institute from 2016 – 2022 Dr. Doliveux is a Veterinary Surgeon by training and has an MBA from INSEAD.

Dr. Frank Mathias

Chief Executive Officer

Dr. Frank Mathias joined Oxford Biomedica's Board in March 2023.

Dr. Mathias was previously the CEO of Rentschler Biopharma SE, which he successfully developed into a leading global, full-service CDMO. Prior to this, Dr. Mathias was CEO of Medigene AG, a publicly listed immuno-oncology company focusing on the development of T-cell-based cancer therapies. Over the course of his 30-year career, Dr. Mathias has also served in senior roles at leading global pharmaceutical companies including Amgen, Servier and Hoechst AG, and in 2019 was awarded the title of "EY Entrepreneur of the Year" in Germany. Dr. Mathias is a pharmacist by training and completed his Doctorate in Pharmacy at Paris VI University.

Dr. Heather Preston

Independent Non-Executive Director

Dr. Heather Preston was appointed to the Board as a Non-Executive Director in March 2018 and was appointed Chair of the Remuneration Committee in June 2020.

Dr. Preston is a Senior Advisor to TPG Biotech. She has over 30 years of experience in healthcare, as a scientist, physician and management consultant and she has been an investor in life sciences and biotechnology for the last 20 years. Dr. Preston holds a degree in Medicine from the University of Oxford.

Robert Ghenchev

Non-Executive Director

Robert Ghenchev was appointed to the Board as a Non-Executive Director in June 2019.

Mr Ghenchev is currently Head of Growth Equity at Novo Holdings. Prior to joining Novo Holdings, he was an investment banker at Moelis & Company and Deutsche Bank in London. Mr Ghenchev has deep corporate finance experience advising life science companies on a wide range of issues. He holds a J.Hons. B.A. degree in Finance and Economics from McGill University and a M.Sc. degree in Financial Economics from the University of Oxford.

Catherine Moukheibir

Independent Non-executive Director

Catherine Moukheibir was appointed to the Board as a Non-Executive Director in December 2021.

Over the course of her career Ms Moukheibir has served in senior executive roles and board positions including at Kymab Limited, Innate Pharma S.A, Ablynx N.V, Genkyotex S.A, MedDay Pharmaceuticals, Zealand Pharma A/S, Zeltia S.A., and Creabilis. Prior to that, she was the CFO of Movetis N.V, overseeing the company's IPO on Euronext and subsequent sale to Shire Pharmaceuticals. She started her career in investment banking and capital markets working in the US and London. Ms Moukheibir holds an MBA and a Masters in Economics from Yale University. Ms Moukheibir has extensive international experience in finance, capital markets and life sciences and is currently serving as a Non-Executive board member with various companies, both listed (Biotalys, Ironwood Pharmaceuticals, Inc and MoonLake Therapeutics), and privately owned (CMR Surgical Limited, Asceneuron SA. DNA Script and Noema Pharma).

Leone Patterson

Independent Non-Executive Director

Leone Patterson was appointed to Oxford Biomedica's Board as an Independent Non-Executive Director in April 2023.

Ms Patterson has more than 20 years of public company biotech experience including in the cell and gene therapy industry and has managed significant growth within international commercial companies working across areas including strategy, finance, operations and governance. She is currently the Chief Financial and Business Officer at Tenaya Therapeutics, a clinical-stage company with a mission to discover, develop, and deliver potentially curative therapies, including gene therapy, for heart disease. She is also a Board member at Nkarta, Inc., a clinical-stage cell therapy company. Over the course of her career, Ms Patterson has held leadership roles at Adverum Biotechnologies, Diadexus Inc., and Transcept Pharmaceuticals and, earlier in her career, worked within Novartis, Chiron and KPMG. She holds a B.S. in business administration and accounting from Chapman University, an executive M.B.A. from St. Mary's College and is a Certified Public Accountant (inactive).

Stuart Henderson

Vice Chair (Independent Non-Executive Director)

Stuart Henderson was appointed to the Board as a Non-Executive Director and Chair of the Audit Committee in June 2016. He became Deputy Chair and Senior Independent Director in June 2020. In March 2023, Mr Henderson became Vice Chair when the role of Deputy Chair and Senior Independent Director was divided into two roles. Mr Henderson is also the designated Director by the Board to oversee engagement between the Board and the workforce.

Mr Henderson was previously a partner at Deloitte, where he was Head of European Healthcare and Life Sciences. Prior to this he was a Partner at Arthur Andersen. Mr Henderson has extensive audit and transaction experience and has worked with life sciences businesses for over 35 years. Mr Henderson is a former Director of the Babraham Institute, Biocity Group Limited, Norwich Research Partners LLP and OneNucleus (the Life Sciences trade body for Cambridge and London), and a former Non-Executive Director of Cell Therapy Catapult Limited.

Stuart Paynter

Chief Financial Officer

Stuart Paynter joined the Board as Chief Financial Officer in August 2017.

Mr Paynter has 22 years' experience in the pharmaceutical and healthcare sectors. He qualified as a chartered accountant with Haines Watts before moving to EDS. Mr Paynter subsequently joined Steris, and worked in a variety of roles within the healthcare and life sciences divisions prior to becoming the European Finance Director. Mr Paynter then moved to Shire Pharmaceuticals where he became the Senior Director of Finance Business Partnering for all business outside of the US, transitioning to a corporate finance role before becoming the Global Head of Internal Audit. Prior to joining Oxford Biomedica Mr Paynter was Head of Finance Business Partnering at De La Rue plc. He is a member of the Institute of Chartered Accountants in England and Wales.

Professor Dame Kay Davies Independent Senior Independent Director

Professor Dame Kay Davies was appointed to the Board as a Non-Executive Director in March 2021. In March 2023, Professor Davies became Senior Independent Director when the role of Deputy Chair and Senior Independent Director was divided into two roles.

Professor Davies is a world-leading human geneticist with a research focus on the molecular analysis of neuromuscular and neurological disease. She is currently Professor of Anatomy Emeritus and Co- Director of MDUK Oxford Neuromuscular Centre at the University of Oxford. She was co-founder of Summit Therapeutics Plc, a spinout from her research activities. Professor Davies also sits on the Board of UCB S.A. and was appointed a governor of the Welcome Trust in 2008, serving as Deputy Chair between 2013 and 2017. Professor Davies has a BA in Chemistry and a D.Phil. in Biochemistry from the University of Oxford.

Dr. Michael Hayden

Non-executive Director

Dr. Hayden was appointed to the Board as a Non-Executive Director in July 2021.

He was previously the President of Global R&D and Chief Scientific Officer at Teva Pharmaceuticals Industries Ltd. and has co-founded five biotechnology companies: Prilenia Therapeutics B.V., NeuroVir Therapeutics Inc., Xenon Pharmaceuticals Inc., Aspreva Pharmaceuticals Corp and 89bio, Inc. He currently serves as CEO of Prilenia Therapeutics and represents private and public (Ionis Pharmaceuticals Inc., AbCellera Biologics Inc. and 89Bio Inc.) companies at board level. Dr. Hayden has focused his research primarily on translational medicine, including genetics of diabetes, lipoprotein disorders, Huntington's disease, predictive and personalised medicine, and drug development, and has authored approximately 900 peer-reviewed publications and invited submissions.

Namrata Patel

Independent Non-executive Director

Namrata Patel was appointed to Oxford Biomedica's Board as an Independent Non-Executive Director in April 2022.

Ms Patel has extensive international experience in manufacturing and end to end Supply Chain management, as well as experience in the commercialised regulated industry. She has held positions of increasing seniority in major blue chip companies including Coca Cola, W H Smith Office Supplies, Gillette, and currently leads the Global Beauty Sector Supply Chain in Procter & Gamble, playing a key role in delivering their 2040 Sustainability Ambition Goals. She holds a Masters in Logistics and Management from the Cranfield School of Management, and a BA Hons in Public Administration from the University of South Wales, Mid Glamorgan.

Oxford Biomedica plc Appendix 2: KPMG LLP Statement of Reasons KPMG LLP Tel +44 (0) 20 7311 1000 Audit Fax +44 (0) 20 7311 3311 15 Canada Square London E14 5GL

Private & confidential Oxford Biomedica Plc Windrush Court Transport Way OXFORD OX4 6LT

27 April 2023

Dear Sir/Madam,

Yours faithfully,

KPMG LLP

Audit registration address: 15 Canada Square

United Kingdom

15 Canada Square

London E14 5GL United Kingdom

Our ref AR-1712

Contact William Smith

william.smith@kpmg.co.uk

KPMG LLP Tel +44 (0) 20 7311 1000 Audit Fax +44 (0) 20 7311 3311

Private & confidential Oxford Biomedica Plc Windrush Court Transport Way OXFORD OX4 6LT

Our ref AR-1712 Statement to Oxford Biomedica Plc (no. 03252665) on ceasing to hold office as

Contact William Smith william.smith@kpmg.co.uk

Registered in England No OC301540 Registered office: 15 Canada Square, London, E14 5GL For full details of our professional regulation please refer to 'Regulatory information' under 'About' at www.kpmg.com/uk

27 April 2023 auditors pursuant to section 519 of the Companies Act 2006 The reason connected with our ceasing to hold office is following a commercial

Dear Sir/Madam, the Group, and that KPMG would not participate in the audit tender.

decision based on discussions with the company where it was mutually agreed that they would explore different and fresh perspectives on the conduct of the audit of

Statement to Oxford Biomedica Plc (no. 03252665) on ceasing to hold office as auditors pursuant to section 519 of the Companies Act 2006

The reason connected with our ceasing to hold office is following a commercial decision based on discussions with the company where it was mutually agreed that they would explore different and fresh perspectives on the conduct of the audit of the Group, and that KPMG would not participate in the audit tender. Audit registration number: 9188307

Yours faithfully, Canary Wharf, London E14 5GL

KPMG LLP Audit registration number: 9188307 Audit registration address: 15 Canada Square Canary Wharf, London E14 5GL

KPMG LLP, a UK limited liability partnership and a member firm of the KPMG global organisation of independent member firms affiliated with KPMG International Limited, a private English company limited by guarantee. Reference - AR-1712

Document Classification - KPMG Highly Confidential

Registered in England No OC301540 Registered office: 15 Canada Square, London, E14 5GL For full details of our professional regulation please refer to 'Regulatory information' under 'About' at www.kpmg.com/uk

KPMG LLP, a UK limited liability partnership and a member firm of the KPMG global organisation of independent member firms affiliated with KPMG International Limited, a private English company limited by

Reference - AR-1712 Document Classification - KPMG Highly Confidential

Registered in England No. 3252665

Registered Office Windrush Court, Transport Way, Oxford, OX4 6LT

guarantee.