3SBio Inc. — AGM Information 2023

May 22, 2023

(Incorporated in the Cayman Islands with limited liability)

22 May 2023

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（於開曼群島註冊成立的有限責任公司）

(Stock Code 股份代號 : 1530)

Dear Shareholders,

3SBIO INC. (the “Company”)

– Publication of Circular of 2023 Annual General Meeting, Notice of 2023 Annual General Meeting and Proxy Form for 2023 Annual General Meeting (collectively, the “Current Corporate Communication”)

Please be informed that the English and Chinese versions of the Company’s Current Corporate Communication are available on the Company’s website at www.3sbio.com (under "Investor" tab) and the HKExnews’ website at www.hkexnews.hk, or the arranged printed form(s) of the Current Corporate Communication is enclosed (if applicable). You may access the Current Corporate Communication on the Company’s website or by browsing through the HKExnews’ website.

For shareholders who choose or are deemed to have consented to receive Corporate Communications [(Note)] by electronic means but if for any reason any shareholder has difficulty receiving or gaining access to the Corporate Communications, or if you want to receive another printed language version of the Current Corporate Communication (if applicable), the Company will promptly, upon your request, send you a printed version free of charge. Please make your request to the Company’s share registrar, Computershare Hong Kong Investor Services Limited (the “ Share Registrar ”), at 17M Floor, Hopewell Centre, 183 Queen’s Road East, Wanchai, Hong Kong or by email at 3sbio.ecom@computershare.com.hk.

Please also note that you are entitled to change your choice of language and/or means of receipt of the Company’s future Corporate Communications by giving reasonable notice in writing or by completing, signing and returning the Change Request Form on the reverse side by post or hand delivery to the Share Registrar or by email at 3sbio.ecom@computershare.com.hk. If you post from Hong Kong, you may use the mailing label at the bottom of the Change Request Form and need not affix a stamp when returning your Change Request Form. Otherwise, please affix an appropriate stamp. The Change Request Form may also be downloaded from the Company’s website at www.3sbio.com or the HKExnew’s website at www.hkexnews.hk.

If you have any queries relating to this letter, please call the Share Registrar’s telephone hotline at (852) 2862 8688 during business hours from 9:00 a.m. to 6:00 p.m. (Monday to Friday, excluding public holidays) or send an email to 3sbio.ecom@computershare.com.hk.

By Order of the Board 3SBio Inc. Dr. LOU Jing Chairman

Note: Corporate Communications means any document(s) including, but not limited to, (a) annual report and, where applicable, summary financial report; (b) interim report and, where applicable, summary interim report; (c) notice of meeting; (d) listing document; (e) circular; and (f) proxy form.

各位股東：

三生制葯（「本公司」）

– 發佈 2023 股東週年大會通函 、 2023 股東週年大會通告及 2023 股東週年大會代表委任表格（統稱 「 本次公司通訊」）

謹通知 閣下本公司的本次公司通訊的中、英文版本已載列於本公司網站（www.3sbio.com ） ( 見“投資者”頁面）及香港交易 所披露易網站（www.hkexnews.hk ），歡迎瀏覽；或 ( 如適用 ) ，現 按安排附上本次公司通訊的印刷本。 閣下可於本公司網 站或瀏覽香港交易所披露易網站獲取本次公司通訊 。

至於已選擇或被視為已選擇收取公司通訊 （附註） 電子版本之股東，若因任何理由在收取或瀏覽公司通訊上遇到困難，或 閣 下欲收取本次公司通訊文件之另一語言印刷本（如適用者），本公司將於收到 閣下之要求後，迅即免費寄發一份印刷本 予 閣下。請把上述要求寄回本公司股份登記處「香港中央證券登記有限公司」（「 股份登記處 」），地址為香港灣仔皇后 大道東 183 號合和中心 17M 樓或以電郵發送至 3sbio.ecom@computershare.com.hk。

閣下有權更改收取今後刊發之公司通訊的語言版本及 / 或收取方式。 閣下可寄發適當書面通知或填妥、簽署及寄回或親手 交回本函背面的更改回條予本公司股份登記處或透過電郵至 3sbio.ecom@computershare.com.hk。倘若 閣下在香港投寄，可使用 更改回條內的郵寄標籤寄回, 而毋須貼上郵票；否則，請貼上適當的郵票。更改回條亦可於本公司網站（www.3sbio.com）或香港 交易所披露易網站（www.hkexnews.hk ）內下載。

如 閣下對本函內容有任何疑問，請於辦公時間內星期一至星期五（公眾假期除外）上午9時正至下午6時正致電股份登記處電話熱 。 線(852) 2862 8688 或電郵至 3sbio.ecom@computershare.com.hk

承董事會命 三生制葯 董事長 婁競博士

2023 年 05 月 22 日

附註：公司通訊包括但不限於： (a) 年度報告及財務摘要報告（如適用）； (b) 中期報告及中期摘要報告（如適用）； (c) 會議通告； (d) 上市文件； (e) 通函；及 (f) 委任代表表格。

22052023 1 0

CCS5207 SBOH

Shareholder Name and Address: 股東之姓名及地址:

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Change Request Form 更改回條

To: 3SBio Inc. (the “Company”) 致 : 三生制葯（「本公司」） (Stock Code: 1530) （股份代號 : 1530 ） c/o Computershare Hong Kong Investor Services Limited 經香港中央證券登記有限公司 17M Floor, Hopewell Centre, 183 Queen’s Road East 香港灣仔皇后大道東 183 號 Wanchai, Hong Kong 合和中心 17M 樓

I/We would like to receive all future corporate communications* of the Company (“Corporate Communications”) in the manner as indicated below: 本人／吾等欲以下列方式收取 貴公司日後之所有公司通訊*（「公司通訊」）：

• (Please mark （ X ） in ONLY ONE of the following boxes) （請從下列選擇中，僅在其中 一個空格 內劃上「 X 」號）

• to read the receive a printed notification letter of the publication of Corporate Communications on the Company’s website; website version of Corporate Communications published on the Company’s website in place of receiving printed copies; and OR 瀏覽在本公司網站發佈之公司通訊之 網上版本 ，以代替收取印刷本，並收取公司通訊已在本公司網站發佈的通知函印刷本； 或

• to receive the 僅收取公司通訊之 printed English version 英文印刷本 ； 或 of Corporate Communications ONLY; OR

• to receive the 僅收取公司通訊之 printed Chinese version 中文印刷本 ； 或 of Corporate Communications ONLY; OR

• to receive both printed English and Chinese versions of Corporate Communications.

• □ 同時收取公司通訊之 英文及中文印刷本 。

Name(s) of shareholder(s)[[#]]

Name(s) of shareholder(s)[[#]] Date 股東姓名 [#] 日期

(Please use ENGLISH BLOCK LETTERS 請用英文正楷填寫 )

Shareholder(s) registered address

股東的登記地址

Contact telephone number

聯絡電話號碼

# You are required to fill in the details if you download this change request form from the Company’s website.

假如閣下從本公司網站下載本更改回條，請必須填上有關資料。

Signature(s) 簽署

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Notes 附註：

1. Please complete all your details clearly.

請 閣下清楚填妥所有資料。

1. If your shares are held in joint names, the shareholder whose name stands first on the register of members of the Company in respect of the joint holding should sign on this Change Request Form in order to be valid.

   • 如股份为聯名持有，則本更改回條須由在本公司股東名冊上就聯名持有股份其姓名位列首位的股東簽署，方為有效。

2. Any form with more than one box marked (X), with no box marked (X), with no signature or otherwise incorrectly completed will be void. 如在本更改回條作出超過一項選擇、或未有作出選擇、或未有簽署、或在其他方面填寫不正確，則本更改回條將會作廢。

3. The above instruction will apply to all future Corporate Communications to be sent to shareholders of the Company until you notify otherwise by reasonable notice in writing to the Company’s share registrar, Computershare Hong Kong Investor Services Limited at 17M Floor, Hopewell Centre, 183 Queen’s Road East, Wanchai, Hong Kong or by email at 3sbio.ecom@computershare.com.hk.

   • 上述指示適用於日後向本公司股東發出的所有公司通訊，直至 閣下發出適當的書面通知通知本公司股份登記處「香港中央證券登記有限公司」（地址為香港灣仔皇后大道 東 183 號合和中心 17M 樓）或以電郵發送至 3sbio.ecom@computershare.com.hk 另作選擇為止。

4. Shareholders are entitled to change the choice of means of receipt and language of Corporate Communications at any time by reasonable notice in writing to the Company’s share registrar (at the above address) or by email at 3sbio.ecom@computershare.com.hk.

   • 股東有權在任何時候發出適當的書面通知予本公司股份登記處（地址如上）或以電郵發送至3sbio.ecom@computershare.com.hk，要求更改公司通訊的語言版本及收取方式。

5. For the avoidance of doubt, we do not accept any special instructions written on this Change Request Form.

   • 為免存疑，任何在本更改回條上的手寫的特别指示，本公司將不予處理。

• *Corporate Communications means any document(s) including, but not limited to, (a) annual report and, where applicable, summary financial report; (b) interim report and, where applicable, summary interim report; (c) notice of meeting; (d) listing document; (e) circular; and (f) proxy form.

公司通訊包括但不限於： (a) 年度報告及財務摘要報告（如適用）； (b) 中期報告及中期摘要報告（如適用）； (c) 會議通告； (d) 上市文件； (e) 通函；及 (f) 委任代表表格。

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Mailing Label 郵寄標籤 Please cut the mailing label and stick it on an envelope to return this Change Request Form to us.

Computershare Hong Kong Investor Services Limited No postage is necessary if posted in Hong Kong . 香港中央證券登記有限公司 Freepost No. 簡便回郵號碼 ： 37 閣下寄回本更改回條時，請將郵寄標籤剪貼於信封上。 Hong Kong 香港 如在本港投寄， 閣下無需支付郵費或貼上郵票。 v.2 March 2016

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