3SBio Inc. — AGM Information 2018

May 18, 2018

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(Incorporated in the Cayman Islands with limited liability)

（於開曼群島註冊成立的有限責任公司）

(Stock Code 股份代號 : 1530)

NOTIFICATION LETTER 通 知 信 函

18 May 2018

Dear Non-registered holders[(1)] ,

3SBIO INC. (the “Company”)

– “ ” Publication of AGM Circular ( Current Corporate Communication )

The English and Chinese versions of the Company’s Current Corporate Communication are available on the Company’s website at www.3sbio.com and the HKExnews’ website at www.hkexnews.hk.

If you would like to receive the printed version of the Current Corporate Communication, please complete the request form on the reverse side (the “ Request Form ”) and sign and return it by post or by hand to the Company’s share registrar c/o Computershare Hong Kong Investor Services Limited (the “ Share Registrar ”) at 17M Floor, Hopewell Centre, 183 Queen’s Road East, Wanchai, Hong Kong. If you post your reply in Hong Kong, you may use the mailing label in the Request Form and need not affix a stamp on the envelope when returning your Request Form. Otherwise, please affix an appropriate stamp. You may also send an email with a sc anned copy of the Request Form to 3sbio.ecom@computershare.com.hk.

Should you have any query in relation to this letter, please call the telephone hotline of the Share Registrar at (852) 2862 8688 during business hours from 9:00 a.m. to 6:00 p.m., Monday to Friday, excluding public holidays.

By Order of the Board 3SBio Inc. Dr. LOU Jing Chairman

Note (1): This letter is addressed to non-registered holders (a “ non-registered holder ” means such person or company whose shares in the Company are held in The Central Clearing and Settlement System (CCASS) and who has notified the Company from time to time through Hong Kong Securities Clearing Company Limited that such person or company wishes to receive Corporate Communications*). If you have sold or transferred your shares in the Company, please disregard this letter and the Request Form on the reverse side.

*Corporate Communications include but not limited to (a) annual report and where applicable, summary financial report; (b) interim report and, where applicable, summary interim report; (c) notice of meeting; (d) listing document; and (e) circular.

各位非登記持有人[(1)] ：

三生制葯（ 「 本公司」）

– 「 發佈股東週年大會通函（ 本次公司通訊文件」）

本公司的本次公司通訊文件之中、英文版本已上載於本公司網站 www.3sbio.com 及香港交易所披露易網站 www.hkexnews.hk，歡 迎查閲。

如 閣下欲收取本次公司通訊文件之印刷本，請 閣下填妥在本函背面的申請表格，並在表格上簽名，並寄回戓親手交回本公司 之股份登記處 ─ 香港中央證券登記有限公司（「 股份登記處 」），地址為香港灣仔皇后大道東183號合和中心17M樓。倘若 閣 下在香港投寄，可使用申請表格内的郵寄標籤寄回，而毋須在信封上貼上郵票；否則，請貼上適當的郵票， 閣下亦可把已填妥 。 之申請表格的掃描副本電郵至3sbio.ecom@computershare.com.hk

閣下如有任何與本函內容有關的疑問，請致電股份登記處電話熱線 (852) 2862 8688 ，辦公時間為星期一至星期五（公眾 假期除外）上午 9 時正至下午 6 時正。

2018 年 5 月 18 日

承董事會命 三生制葯 董事長 婁競博士

附註 (1) ：本函乃向本公司之非登記持有人（「 非登記持有人 」指存放本公司股份於中央結算及交收系統的人士或公司，透過香港中央結算有限公司不時向本公司發出通知，表示該等人士或公司希望收 到公司通訊 * ）發出。如果閣下已經售出或轉讓所持有的所有本公司股份，則無需理會本函件及所附之申請表格。

• 公司通訊包括但不限於： (a) 年度報告及財務摘要報告（如適用）； (b) 中期報告及中期摘要報告（如適用）； (c) 會議通告； (d) 上市文件；及 (e) 通函。

18052018 1 0

CCS3632 SBOH_NRH

Non-registered holder Name and Address: 非登記股東之姓名及地址:

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Request Form 申請表格

To: 3SBio Inc. (the “Company”) 致： 三生制葯（「公司」） (Stock Codes: 1530) （股份代號： 1530 ） c/o Computershare Hong Kong Investor Services Limited 經香港中央證券登記有限公司 17M Floor, Hopewell Centre, 183 Queen’s Road East, 香港灣仔皇后大道東 183 號 Wanchai, Hong Kong 合和中心 17M 樓

To: 3SBio Inc. (the “Company”)

I/We would like to receive the Corporate Communications * of the Company (“ Corporate Communications ”) in the manner as indicated below: 本人／我們希望以下列方式收取 貴公司之公司通訊 * （「 公司通訊 」）：

(Please mark ONLY ONE （ X ） of the following boxes)

（請從下列選擇中，僅在其中 一個空格 內劃上「 X 」號）

□ to receive the 僅收取公司通訊之 printed English version 英文印刷本；或 of all Corporate Communications ONLY; or

□ to receive the 僅收取公司通訊之 printed Chinese version 中文印刷本；或 of all Corporate Communications ONLY; or

to receive both printed English and Chinese versions of all Corporate Communications. □ 同時收取公司通訊之 英文及中文各一份印刷本 。

Name Contact telephone number 姓名 聯絡電話號碼 Signature Date 簽名 日期

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Notes 附註：

1. Please complete all your details clearly.

請 閣下清楚填妥所有資料。

1. This Request Form is to be completed by non-registered holders (a “ non-registered holder ” means such person or company whose shares in the Company are held in the Central Clearing and Settlement System (CCASS) and who has notified the Company from time to time through Hong Kong Securities Clearing Compan y Limited that such person or company wishes to receive Corporate Communications).

   • 本函是由本公司之非登記持有人（「 非登記持有人 」指存放本公司股份於中央結算及交收系統的人士或公司，透過香港中央結算有限公司不時向本公司發出通知表示該等人士或公司希望 收到公司通訊）填妥的。

2. Any form with more than one box marked (X), with no box marked (X), with no signature or otherwise incorrectly completed will be void. 如在本表格作出超過一項選擇、或未有作出選擇、或未有簽署、或在其他方面填寫不正確，則本表格將會作廢。

3. For the avoidance of doubt, we do not accept any special instructions written on this Change Request Form . 為免存疑，任何在本申請表格上的額外手寫指示，本公司將不予處理。

• Corporate Communications include but not limited to (a) annual report and where applicable, summary financial report; (b) interim report and, where applicable, summary interim report; (c) notice of meeting; (d) listing document; and (e) circular.

公司通訊包括但不限於： (a) 年度報告及財務摘要報告（如適用）； (b) 中期報告及中期摘要報告（如適用）； (c) 會議通告； (d) 上市文件；及 (e) 通函。

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郵寄標籤 MAILING LABEL

閣下寄回此更改指示回條時，請將郵寄標籤剪貼於信封上。 如在本港投寄毋須貼上郵票。

Please cut the mailing label and stick this on the envelope to return this Change Request Form to us.

No postage stamp necessary if posted in Hong Kong .

香港中央證券登記有限公司 Computershare Hong Kong Investor Services Limited 簡便回郵號碼 Freepost No. 37 香港 Hong Kong

v.2 March 2016