Mithra Pharmaceuticals S.A.

Report Publication Announcement • Apr 16, 2018

MITHRA RELEASES 2017 ANNUAL REPORT AND INVITATION TO ITS ORDINARY GENERAL SHAREHOLDERS' MEETING

Liège, Belgium 16 April 2018 – 7:30 AM: Mithra (Euronext Brussels: MITRA), a company specialized in Women's Health, is pleased to announce the publication of its 2017 Annual Report and the invitation to its Ordinary General Shareholders' meeting.

Annual Report

The Annual Report which outlines Mithra's achievements in 2017 includes the following information:

• Overview of Mithra's R&D pipeline and Letter to Shareholders;
• Highlights of Mithra's Strategy and Outlook for 2018;
• Management Report;
• Remuneration Report;
• Financial statements and notes.

François Fornieri, CEO Mithra : "2017 has been a crucial year of progress for Mithra during which we advanced our key clinical programs. These include the pivotal Phase III trials of our innovative 5th generation oral contraceptive, Estelle®, and the Phase II study of Donesta®, our novel candidate for menopausal symptoms. Also, business development activity accelerated significantly, marked by important commercialization contracts, including Libbs for Estelle® in Brazil, Fuji Pharma for Donesta® in Japan and Mayne Pharma for Myring™ in the US.

We look forward to building on the progress made to date, with important read-outs for both the Donesta® and Estelle® clinical trials during 2018, and the addition of commercial partners for our portfolio in new territories. We are confident that with Donesta® and Estelle®, we have two potential blockbusters in our pipeline that position Mithra for long-term international growth as a transformational leader in Women's Health."

Mithra releases its Annual Report in English and French. In case of interpretation differences, the French version will prevail.

The report is available in English and French and can be downloaded on the website investors.mithra.com as a PDF file.

Ordinary General Shareholders' meeting

The Ordinary General Shareholders' meeting of Mithra Pharmaceuticals will be held on May 17 2018 at 5:00 PM (CEST) in Liège (Belgium). Mithra is pleased to invite its shareholders.

The notice for the Ordinary General Shareholders' meeting including a description of the formalities to participate in the Meeting is available on the website investors.mithra.com.

Pour plus d'informations, veuillez contacter:

Investor Relations

Sofie Van Gijsel, IRO +32 485 19 14 15 investorrelations@mithra.com svangijsel@mithra.com

Press

Julie Dessart, Chief Communication Officer +32 4 349 28 22 / +32 475 86 41 75 press@mithra.com

A propos de Mithra

Mithra (Euronext : MITRA) s'engage à offrir des alternatives innovantes dans le domaine de la santé féminine en mettant particulièrement l'accent sur la fertilité, la contraception et la ménopause. L'objectif de Mithra est de développer de nouveaux produits qui répondent aux besoins des femmes en termes de sécurité et de facilité d'utilisation. Ses deux produits candidats phares, Estelle®, un contraceptif oral de cinquième génération, et Donesta®, un traitement hormonal de nouvelle génération, sont basés sur l'E4 (Estetrol), un œstrogène naturel unique. Par ailleurs, la société développe, fabrique et commercialise des solutions thérapeutiques complexes et offre à ses partenaires un éventail complet en matière de recherche, de développement et de fabrication spécialisée au sein de sa plateforme Mithra CDMO. Mithra a été fondée en 1999 en tant que spin-off de l'Université de Liège par M. François Fornieri et le Prof. Dr. Jean-Michel Foidart et est basée à Liège, en Belgique. Pour plus d'informations, rendez-vous sur : www.mithra.com

Important information

The contents of this announcement include statements that are, or may be deemed to be, "forwardlooking statements". These forward-looking statements can be identified by the use of forward-looking terminology, including the words "believes", "estimates," "anticipates", "expects", "intends", "may", "will", "plans", "continue", "ongoing", "potential", "predict", "project", "target", "seek" or "should", and include statements the Company makes concerning the intended results of its strategy. By their nature, forward-looking statements involve risks and uncertainties and readers are cautioned that any such forward-looking statements are not guarantees of future performance. The Company's actual results may differ materially from those predicted by the forward-looking statements. The Company undertakes no obligation to publicly update or revise forward-looking statements, except as may be required by law.

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