Mithra Pharmaceuticals S.A.

Board/Management Information • Apr 25, 2023

Personal address Personal

Chaussée de Louvain 574A Birthdate: December 27, 1958 B-1380 Lasne Citizenship: Belgian BELGIUM Cell Phone: + 32 475 49 69 29 Email : chomsy@lsshealth.com

Business address

Life Science Strategy Consulting Chaussée de Louvain 574A B-1380 Lasne BELGIUM

BUSINESS EXPERIENCE

April 2020 – Dec 2022	Capstan Therapeutics Inc. Founder, Interim CEO and Board Member
	Teefib Inc. is a platform biotechnology company developing in-vivo immune cell engineering solutions using targeted Lipid Nanoparticles. The Company co-founders are Carl June and Bruce Levine, Drew Weissman and Hamideh Parhiz, Ellen Pure and Steve Albelda, Jonathan Epstein and Haig Aghajanian. We raised a seed round of USD 63M in November 2021 and, under my tenure, we closed a Series A of USD 102M 7 month later in June 2022. The company is focused on 4 Therapeutic Areas, Oncology, Fibrosis, Autoimmunity and Blood monogenic disorders. At the time I handed, we had a full executive team hired as well as 48 headcounts, in two locations, Philadelphia and San Diego.
Sept. 2004-December 2019 Celyad SA
	Founder, Chief Executive Officer and Board member
	Celyad SA is a biotechnology company currently active in the field of CAR T cells for oncology applications. Celyad was initially called Cardio3 BioSciences, and, at its inception, developed a stem cell based treatment for cardiovascular diseases. The company was founded on a technology invented by a researcher from Harvard Medical School. The Company reinvented itself when we acquired our NKG2D based CAR T asset from Dartmouth college, which allowed us to list on NASDAQ in 2015.
2017 -	Miracor SA Board Member
Jan 1992- Aug 2004	GUIDANT CORPORATION -
Sept 1999- Aug 2004	Director Clinical Research Vascular Intervention Europe (EMEA) • Setting up and running the clinical research organization for the Vascular Intervention division, including Coronary, Peripheral, Neurology and Vascular Surgery – When I left, the group had 40 employees and performed multiple large marketing and product approval studies. I have developed strong contacts with the key stakeholders in the US as well as in Europe, in interventional cardiology (Physicians and industry)
Jan 2001-Aug 2004	Director Business Development • Negotiated two technology transfers in the field of coronary intervention and stem cells

Sept 1999-Aug 2000	Director Guidant Europe Cardiovascular Institute • Setting up Guidant European Training facility with state of the art virtual reality equipment and Cath lab simulation. Example now followed in the US and Japan.
Jan 1997-Aug 1999	Director Cardiac Rhythm Management Europe (EMEAC) • Marketing, clinicals and new product planning for the European operations of the Cardiac Rhythm Management division of Guidant (CPI and HRT) 175 M US\$ in annual sales (20% CAGR growth). • Strategic Planning for CRM Europe • Managing a team of Marketing Managers, Product Managers, Clinical Director, Medical Sciences Director. • Coordinating US-Europe R & D and business development activities
March 1995-Jan 1997	Director of Clinical Affairs, Cardiac Rhythm Management Europe Managed a team of 8 European Clinical Coordinators, 1 data coordinator, 1 Publication Coordinator, 5 European Research Coordinators, 1 Field Clinical Engineer manager and 6 Field Clinical Engineers. • Implemented a new data collection system with remote data entry capabilities • Initiated the work on a worldwide clinical data base • Participated in multifunctional task teams on globalization
March 1993-Feb. 1995	Country Manager CPI Ventak (implantable defibrillators), Paris, France Managed a team of 3 sales people, 1 business development coordinator and 1 customer service administrative. • Brought market share from 45% to 65% and achieved 40% growth rate on two consecutive years • Raised the average selling price by 12% • Reduced inventory from 120 to 60 days and working capital by 55% • Organized a 400 participants European scientific symposium • Created a young investigators scientific board • Initiated political and administrative contacts to get a reimbursement for the devices
Jan. 1992-March 1993	CPI Pacing European Marketing Associate, London, UK Responsible for the coordination of the European marketing strategy of the pacemaker product lines • Designed and conducted a European market research to determine the value of our key product differences • Developed the new products requirements based on the market research • Coordinated European phase 5 studies • Designed a new computerized inventory and consignment tracking system • Liaised with the country managers to implement the new system, which reduced inventory levels by 40% and consignment losses by 12% • Organized the European launch of a new product line
Jan. 1991-Jan. 1992	MBA, IMD, Lausanne Switzerland
Aug. 1987-Dec. 1990	CENTRE HOSPITALIER MOLIERE LONGCHAMP, Brussels, Belgium 200 beds university hospital Conducted several research projects on various orthopedic subjects and presented some of the results at international congresses
Oct. 1988-Dec. 1990	Resident, Orthopedic Department Surgical, administrative and teaching responsibilities.
July 1987-Oct. 1988	Junior resident with surgical and teaching responsibilities
Aug. 1987-Dec. 1990	BELGIAN RED CROSS AUTOPHERESIS CENTER The largest blood bank in Belgium dealing blood derivatives. MD in charge (part time).

EDUCATION 1991	MBA, IMD, Lausanne, Switzerland
1990	Orthopedic Residency, Brussels University, Belgium
1987	Medical Doctorate, Magna Cum Laude, University of Louvain, Brussels, Belgium
1986	FMGEMS certification (qualification to practice medicine in the USA)
LANGUAGES OTHER EXPERIENCE	Fluent: French, English and Arabic
1987	Harvard Medical School Surgery Residency, Boston, USA