Mithra Pharmaceuticals S.A.

Major Shareholding Notification • Sep 12, 2023

Publication of a Transparency Notification Received from Armistice Capital, LLC

Liege, Belgium, 12 September 2023 – 5:45 pm CEST – Mithra (Euronext Brussels: MITRA), a company dedicated to Women's Health, today announces, in accordance with Article 14 of the Belgian Law of 2 May 2007 regarding the publication of major shareholdings in issuers whose securities are admitted to trading on a regulated market (the "Transparency Law"), that it received a notification of transparency from Armistice Capital, LLC, with registered offices at 510 Madison Avenue, 7th Floor, NY 10022, New York, USA, on 31 August 2023.

Armistice Capital, LLC notified Mithra that it has actively crossed above the legal 10% threshold on 28 August 2023 as a result of the completion of the Private Placement completed on the same date¹ . Armistice Capital, LLC now holds 14.58% (10,000,000 shares) of the 68,587,058 shares currently outstanding.

The detailed transparency notifications are available on the Investors section of Mithra (mithra.com/en/investors/). An updated overview of the Mithra's shareholders structure will be included in the corporate governance charter of Mithra, which will be made available on its website.

For more information, please contact:

Mithra Pharmaceuticals SA	Investor & media relations
David Horn Solomon	Chris Maggos
Chief Executive Officer	Cohesion Bureau
investorrelations@mithra.com	chris.maggos@cohesionbureau.com
	+41 79 367 6254

About Mithra

Mithra Pharmaceuticals SA (Euronext: MITRA) is a Belgian biopharmaceutical company dedicated to transforming Women's Health by offering new choices through innovation, with a particular focus on contraception and menopause. Mithra's goal is to develop products offering better efficacy, safety and convenience, meeting women's needs throughout their life span. Mithra explores the potential of the unique native estrogen estetrol in a wide range of applications in women health and beyond. After having successfully launched the first estetrol-based product in 2021, the contraceptive pill Estelle® , Mithra is now focusing on its second product Donesta® , the next-generation hormone therapy. Mithra also offers partners a complete spectrum of solutions from early drug development, clinical batches and commercial manufacturing of complex polymeric products (vaginal ring, implants) and complex liquid injectables and biologicals (vials, pre-filled syringes or cartridges) at its technological platform Mithra CDMO. Active in more than 100 countries around the world, is headquartered in Liège, Belgium. www.mithra.com

¹ https://www.mithra.com/en/mithra-completes-eur-20-million-private-placement-in-equity/

11-09-2023

Important information

The contents of this announcement include statements that are, or may be deemed to be, "forward-looking statements". These forward-looking statements can be identified by the use of forward-looking terminology, including the words "believes", "estimates," "anticipates", "expects", "intends", "may", "will", "plans", "continue", "ongoing", "potential", "predict", "project", "target", "seek" or "should", and include statements the Company makes concerning the intended results of its strategy. By their nature, forward-looking statements involve risks and uncertainties and readers are cautioned that any such forward-looking statements are not guarantees of future performance. The Company's actual results may differ materially from those predicted by the forward-looking statements. The Company undertakes no obligation to publicly update or revise forward-looking statements, except as may be required by law.

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