Report Publication Announcement • Nov 16, 2017
Report Publication Announcement
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BerGenBio to present at Jefferies 2017 London Healthcare Conference
Bergen, Norway, 16 November 2017 - BerGenBio ASA (OSE:BGBIO), a clinical-stage
biopharmaceutical company developing novel, selective Axl kinase inhibitors for
multiple cancer indications, announces that the Company will be presenting at
the Jefferies 2017 London Healthcare Conference in London, UK, on 16 November
The presentation will be delivered by Richard Godfrey, CEO, and the presented
slides are available on the Company's website: www.bergenbio.com.
-Ends-
About BerGenBio ASA
BerGenBio ASA is a clinical-stage biopharmaceutical company focused on
developing a pipeline of first-in-class Axl kinase inhibitors to treat multiple
cancer indications. The Company is a world leader in understanding the essential
role of Axl kinase in mediating cancer spread, immune evasion and drug
resistance in multiple aggressive solid and haematological cancers.
BerGenBio's lead product, BGB324, is a selective, potent and orally bio
-available small molecule Axl inhibitor in four Company sponsored Phase II
clinical trials in major cancer indications, with read-outs anticipated in the
second half of 2018. It is the only selective Axl inhibitor in clinical
development.
The Company sponsored clinical trials are:
· BGB324 as a single agent and combination therapy in acute myeloid leukaemia
(AML) / myeloid dysplastic syndrome (MDS)
· BGB324 with TARCEVA® (erlotinib) in advanced EGFR mutation driven non-small
cell lung cancer (NSCLC)
· BGB324 with KEYTRUDA in advanced adenocarcinoma of the lung, and
· BGB324 with KEYTRUDA in triple negative breast cancer (TNBC).
The clinical trials combining BGB324 with KEYTRUDA in adenocarcinoma of the lung
and TNBC are conducted in collaboration with Merck & Co., Inc., Kenilworth,
N.J., USA.
In addition, a number of investigator-sponsored trials are underway, including a
trial to investigate BGB324 with either MEKINIST® (trametinib) plus TAFINLAR®
(dabrafenib) or KEYTRUDA in advanced melanoma, as well as a trial combining
BGB324 with docetaxel in advanced NSCLC.
BerGenBio is simultaneously developing a companion diagnostic test to identify
patient subpopulations most likely to benefit from treatment with BGB324. This
will facilitate more efficient registration trials and support a precision
medicine based commercialisation strategy.
The Company is also developing a diversified pre-clinical pipeline of drug
candidates, including BGB149, an anti-Axl monoclonal antibody.
For further information, please visit: www.bergenbio.com
KEYTRUDA® is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary
of Merck & Co., Inc., Kenilworth, NJ, USA, TARCEVA® is a registered trademark of
OSI Pharmaceuticals, LLC., marketed by Roche-Genentech. TAFLINAR® is a
registered trademark of Novartis International AG and MEKINIST® is a registered
trademark of GSK plc.
Contacts
Richard Godfrey
CEO, BerGenBio ASA
+47 917 86 304
Tom Henrik Sundby
Finance Director, BerGenBio ASA
+47 477 54 415
Media Relations
David Dible, Mark Swallow, Marine Perrier
Citigate Dewe Rogerson
+44 207 638 9571
Forward looking statements
This announcement may contain forward-looking statements, which as such are not
historical facts, but are based upon various assumptions, many of which are
based, in turn, upon further assumptions. These assumptions are inherently
subject to significant known and unknown risks, uncertainties and other
important factors. Such risks, uncertainties, contingencies and other important
factors could cause actual events to differ materially from the expectations
expressed or implied in this announcement by such forward-looking statements
This information is subject to the disclosure requirements pursuant to section 5
-12 of the Norwegian Securities Trading Act.
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