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BerGenBio

Board/Management Information Nov 21, 2018

3555_rns_2018-11-21_eabcad72-ef45-4426-81d1-1ae827e65a85.html

Board/Management Information

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BerGenBio appoints cancer drug development specialist Alan Barge MD as interim Chief Medical Officer

BerGenBio appoints cancer drug development specialist Alan Barge MD as interim Chief Medical Officer

Further senior organisational changes made in preparation for advancing

bemcentinib into the next stage of clinical development in multiple aggressive

cancers

Bergen, Norway, 22nd November 2018 - BerGenBio ASA (OSE: BGBIO), a clinical

-stage biopharmaceutical company developing novel, oral, selective AXL kinase

inhibitors for multiple cancer indications, is delighted to announce the

appointment of Alan Barge MD as Interim Chief Medical Officer and member of the

leadership team. The Company also announces further senior organisational

changes and a strengthening of its clinical operations as it prepares for the

intended advancement of its lead candidate bemcentinib into the next stages of

clinical development.

Dr Barge is a board-certified oncologist and haematologist, with more than 25

years of experience in cancer drug development, spent primarily at AstraZeneca

and Amgen. He spent over 12 years at AstraZeneca, where he was VP and Head

Oncology and Infection, during which time he was responsible for the development

of Iressa® (gefitinib) for non-small cell lung cancer (NSCLC) and the

translational research that resulted in the successful personalised medicine

strategy for AZ. Prior to AZ, Dr Barge was European and Global Medical Director

at Amgen, at which he was responsible for European approval and label extensions

for several of Amgen's cancer therapies. More recently, Dr Barge has been

actively involved in the biotech sector in both CMO and non-executive positions,

including CMO of Carrick Therapeutics (UK and Ireland) and SVP Oncology at ASLAN

Pharmaceuticals (Singapore).

Dr Barge will work as part of BerGenBio's leadership team on an interim basis

until a permanent CMO is appointed.

Richard Godfrey, Chief Executive Officer of BerGenBio, commented: "We are

delighted to welcome Alan to the team. His vast experience from developing

successful cancer drugs with AstraZeneca and Amgen will be most valuable in

forming and executing the Company's clinical and regulatory strategy for

bemcentinib as we enter the next phase of development. We anticipate further

results from our phase II proof-of-concept studies of bemcentinib in NSCLC and

AML in the coming months, and aim to start a randomised phase 2 trial programme

in these indications in 2019."

In addition, BerGenBio announces the promotion of Dr Anthony Brown to Chief

Scientific Officer from Director of Research, succeeding BerGenBio co-founder

Professor James Lorens, who becomes a Senior Scientific Advisor to the Company.

Murray Yule, BerGenBio's Clinical Development Officer, will leave the Company

with effect from 30 November 2018. Further, as noted during the Company's Q3

2018 results presentation, Dr Tone Bjaaland has recently been appointed as

Director of Clinical Operations (>25 years' experience in clinical research) and

further strengthens the team.

About BerGenBio ASA

BerGenBio is a clinical-stage biopharmaceutical company focused on developing

transformative drugs targeting AXL as a potential cornerstone of therapy for

advanced and aggressive cancers. The company's proprietary lead candidate,

bemcentinib, is a potential first-in- class, selective AXL inhibitor in a broad

phase II clinical development programme. Ongoing clinical trials are

investigating bemcentinib in multiple solid and haematological tumours, in

combination with current and emerging therapies (including immunotherapies,

targeted therapies and chemotherapy), and as a single agent.

In parallel, BerGenBio is developing a companion diagnostics test to identify

patient populations most likely to benefit from bemcentinib: this is expected to

facilitate more efficient registration trials and support a precision medicine

-based commercialisation strategy.

BerGenBio is based in Bergen, Norway with a subsidiary in Oxford, UK. The

company is listed on the Oslo Stock Exchange (ticker: BGBIO). www.bergenbio.com

Contacts

Richard Godfrey CEO, BerGenBio ASA

+47 917 86 304

Rune Skeie, CFO, BerGenBio ASA

[email protected]

+47 917 86 513

International Media Relations

David Dible, Mark Swallow, Marine Perrier, Citigate Dewe Rogerson

[email protected]

+44 207 638 9571

Media Relations in Norway

Jan Petter Stiff, Crux Advisers

[email protected]

+47 995 13 891

Forward looking statements

This announcement may contain forward-looking statements, which as such are not

historical facts, but are based upon various assumptions, many of which are

based, in turn, upon further assumptions. These assumptions are inherently

subject to significant known and unknown risks, uncertainties and other

important factors. Such risks, uncertainties, contingencies and other important

factors could cause actual events to differ materially from the expectations

expressed or implied in this announcement by such forward-looking statements.

This information is subject to the disclosure requirements pursuant to section 5

-12 of the Norwegian Securities Trading Act

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