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argenx SE

Report Publication Announcement Aug 21, 2014

6221_iss_2014-08-20_141f8ef8-7a6a-4822-8c7d-f2b5fb4e251d.pdf

Report Publication Announcement

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arGEN-X: Notice of Results for the First Half 2014 and Business Update

20 August 2014

Breda, the Netherlands / Ghent, Belgium – arGEN-X N.V. (Euronext Brussels: ARGX), a clinical-stage biopharmaceutical company focused on creating and developing differentiated therapeutic antibodies for the treatment of cancer and severe autoimmune diseases, will release its maiden results for the first half 2014 and a business update on Wednesday 27 August 2014. The full report will be available on arGEN-X' website www.argen-x.com in the Investors section from 7am CET.

About arGEN-X

arGEN-X is a clinical-stage biopharmaceutical company focused on creating and developing differentiated therapeutic antibodies for the treatment of cancer and severe autoimmune diseases. arGEN-X has generated a pipeline of differentiated clinical and preclinical antibody candidates using its SIMPLE Antibody™ discovery platform. SIMPLE Antibody™ has a particular strength in addressing novel, complex disease targets that are difficult to access using established antibody technology platforms. Proprietary Fc engineering technologies (NHance® and ABDEG™) and POTELLIGENT® technology (licensed from BioWa, inc.) further enhance the therapeutic properties of SIMPLE Antibody™ leads in terms of tissue penetration/residence time in the body, ability to clear disease targets or pathogenic antibodies and cell-killing potency through Antibody-Dependent Cell-mediated Cytotoxicity (ADCC), respectively. arGEN-X has leveraged its suite of antibody technologies in forging strategic collaborations with pharmaceutical and biotechnology companies to provide new approaches to diseases with unmet medical needs.

arGEN-X is listed on the Euronext Brussels exchange under the symbol ARGX.

www.arGEN-X.com

SIMPLE Antibody™, NHance® and ABDEG™ are trademarks of arGEN-X NV POTELLIGENT® is a trademark of BioWa Inc.

For further information, please contact:

Tim Van Hauwermeiren, Chief Executive Officer Eric Castaldi, Chief Financial Officer +32 (0)9 243 40 70 [email protected]

Mark Swallow/David Dible Citigate Dewe Rogerson +44 207 282 2948 [email protected]

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, DIRECTLY OR INDIRECTLY, IN OR INTO THE UNITED STATES, AUSTRALIA, CANADA, SOUTH AFRICA OR JAPAN

Beth DelGiacco (US IR) Stern Investor Relations +1 212 362 1200 [email protected]

Neither this message nor the information contained in it may be taken, transmitted or distributed into the United States, Australia, Canada, South Africa or Japan. This message is not an offer of securities for sale in the United States, Australia, Canada, South Africa or Japan or any jurisdiction in which such an offer or solicitation is unlawful. The securities of arGEN-X have not been and will not be registered under the U.S. Securities Act of 1933, as amended (the "Securities Act") or under the securities legislation of any state of the United States. Securities may not be offered or sold in the United States absent registration or an exemption from registration under the Securities Act. Any public offering of securities to be made in the United States must be made by means of a prospectus that may be obtained from the issuer and that contains detailed information about the company and management, as well as financial statements.

Forward-looking Statements

The contents of this announcement include statements that are, or may be deemed to be, "forwardlooking statements". These forward-looking statements can be identified by the use of forwardlooking terminology, including the terms "believes", "estimates", "anticipates", "expects", "intends", "may", "will", or "should", and include statements arGEN-X makes concerning the intended results of its strategy. By their nature, forward-looking statements involve risks and uncertainties and readers are cautioned that any such forward-looking statements are not guarantees of future performance. arGEN-X' actual results may differ materially from those predicted by the forward-looking statements. arGEN-X undertakes no obligation to publicly update or revise forward-looking statements, except as may be required by law.

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