22nd Century Group, Inc. — Director's Dealing 2025

Nov 13, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: 22nd Century Group, Inc. (XXII)
CIK: 0001347858
Period of Report: 2025-11-10

Reporting Person: Otto Daniel A (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-11-10	Common Stock	A	37146	—	Acquired	37871	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-11-10	Stock option (right to buy)	$1.27	A	111439	Acquired	2035-11-10	Common Stock (111439)	Direct

Holdings (Derivative)

Security	Exercise Price	Expiration	Underlying	Shares	Ownership
Stock option (right to buy)	$46.23	2035-03-10	Common Stock (2176)	2176	Direct

Footnotes

F1: The restricted stock units vest 1/3 per year on November 10, 2026, 2027 and 2028, subject to continued service with the Company.

F2: The amount shown reflects the number of shares held following the reported transaction, as adjusted for a 1-for-23 stock split effectuated by the issuer on June 20, 2025.

F3: Options vest 1/3 per year on the anniversary of the date of grant, subject to continued service with the Company.