Novonesis AS

Board/Management Information • Sep 18, 2008

TRADING BY MANAGEMENT IN NOVOZYMES A/S B SHARES

September 18, 2008

In accordance with Section 28a of the Danish Securities Trading Act, Novozymes reports the following transactions under ISIN DK0010272129, Novozymes B shares under the symbol NZYM B.

Name	Relation/ Category of close relation	Trading date	Character of the transaction	No. of shares traded Buy (+) / Sell (-)	Market value of shares traded (DKK)
Peder Holk Nielsen	EVP, Enzymes Business	18/9 2008	Share options	- 10,200	4,980,550

Contact persons:

Press and media: Investor relations:

Johan Melchior Tel. (direct): +45 4446 0690 Tel. (mobile): +45 3077 0690

Paige Donnelly (USA) Tel. (direct): +1 919 494 3209 Tel. (mobile): +1 919 218 4501

Camilla Kinch Jensen Tel. (direct): +45 4446 0852 Tel. (mobile): +45 3077 0852

Tobias Bjørklund (USA) Tel. (direct): +1 919 494 3483 Tel. (mobile): +1 919 649 2565

Novozymes is the world leader in bioinnovation. Together with customers across a broad array of industries we create tomorrow's industrial biosolutions, improving our customers' business and the use of our planet's resources. Read more at www.novozymes.com.

Company announcement no. 10, 2008 Page 1 of 1 Novozymes A/S Investor Relations

Krogshøjvej 36 2880 Bagsværd Denmark

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Internet: www.novozymes.com CVR number: 10 00 71 27