Novonesis AS

Director's Dealing • Dec 1, 2010

December 1, 2010

In accordance with Section 28a of the Danish Securities Trading Act, Novozymes reports the following transactions under ISIN DK0010272129, Novozymes B shares under the symbol NZYM B.

Name	Relation/ Category of close relation	Trading date	Character of transaction	Volume of transaction Buy (+) / Sell (-)	Value of transaction (DKK)
Ulla Morin	Employee representative of the Board of Directors	30/11 2010	Exercise of Options (purchase of shares)	+ 150	25,350.00
		30/11 2010	Sale of shares	-150	112,880.50

Contact persons:

René Tronborg (Europe) Tel. (direct): +45 4446 2274 Tel. (mobile): +45 3077 2274

Paige Donnelly (USA) Tel. (direct): +1 919 494 3209 Tel. (mobile): +1 919 218 4501

Press and media: Investor relations:

Tobias Bjørklund Tel. (direct): +45 4446 8682 Tel. (mobile): +45 3077 8682

Martin Riise Nielsen Tel. (direct): +45 4446 0738 Tel. (mobile): +45 3077 0738

Thomas Bomhoff (USA) Tel. (direct): +1 919 494 3483 Tel. (mobile): +1 919 649 2565

Novozymes is the world leader in bioinnovation. Together with customers across a broad array of industries we create tomorrow's industrial biosolutions, improving our customers' business and the use of our planet's resources. Read more at www.novozymes.com.

Company announcement no. 16, 2010 Page 1 of 1 Novozymes A/S Investor Relations

Krogshoejvej 36 2880 Bagsvaerd Denmark

Telephone: +45 4446 0000 Fax: +45 4446 9999 Internet: www.novozymes.com CVR number: 10 00 71 27