Novonesis AS

Director's Dealing • Feb 29, 2012

February 29, 2012

In accordance with Section 28a of the Danish Securities Trading Act, Novozymes reports the following transactions under ISIN DK0060336014, Novozymes B shares under the symbol NZYM B.

Name	Relation/ Category of close relation	Trading date	Character of transaction	Volume of transaction Buy (+) / Sell (-)	Value of trans action (DKK)
Thomas Nagy	EVP, Stakeholder Relations	28/2/2012	Sale of shares	-25,000	4,138,500
		28/2/2012	Sale of shares	-35,000	5,813,500
Peder Holk Nielsen	Koncerndirektør Enzyme Business	28/2/2012	Sale of shares	-90,000	14,935,320

Contact persons: Press and media: Investor relations: René Tronborg (Europe) Tel. (direct): +45 4446 2274 Tel. (mobile): +45 3077 2274

Paige Donnelly (USA) Tel. (direct): +1 919 494 3209 Tel. (mobile): +1 919 218 4501 Martin Riise Tel. (direct): +45 4446 0738 Tel. (mobile): +45 3077 0738

Thomas Bomhoff (USA) Tel. (direct): +1 919 494 3483 Tel. (mobile): +1 919 649 2565

Novozymes is the world leader in bioinnovation. Together with customers across a broad array of industries we create tomorrow's industrial biosolutions, improving our customers' business and the use of our planet's resources. Read more at www.novozymes.com.

Company announcement no. 21, 2012 Page 1 of 1 Novozymes A/S Investor Relations

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Telephone: +45 4446 0000 Fax: +45 4446 9999 Internet: www.novozymes.com CVR number: 10 00 71 27