Zealand Pharma

Major Shareholding Notification • Nov 26, 2015

Copenhagen, 2015-11-26 12:35 CET (GLOBE NEWSWIRE) -- 26 November 2015 – Zealand
informs that pursuant to Section 29 of the Danish Securities Act, cf. Executive
order no. 1256 of 4 November 2015 on major shareholders and the Danish
Companies Act section 55, cf. section 56, the company has received a major
shareholder announcement from Bpi Groupe, 27-31 Avenue du Général Leclerc,
94700 Maisons-Alfort, France (French registration no. 507 523 678 R.C.S.
Créteil).

Bpi Group has announced to Zealand that following Zealand’s capital increase as
effected on 8 September 2015 (Company announcement no. 38-15), Bpi Groupe’s
indirect holding, (via its subsidiaries CDC Entreprises Capital Investissement
and Bpi France Participation) of nominally DKK 1,190,215 shares of nominally
DKK 1 each and 1,190,215 voting rights in Zealand Pharma A/S corresponds to
less than 5.00 % of the company’s total share capital and voting rights.

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For further information, please contact:

Hanne Leth Hillman, Senior Vice President for Investor Relations and
Communications

Tel: +45 50 60 36 89, email: hlh@zealandpharma.com

About Zealand Pharma

Zealand Pharma A/S (Nasdaq Copenhagen: ZEAL) (“Zealand”) is a biotech company
with leading-edge scientific expertise in turning peptides into medicines.
Zealand has a growing proprietary pipeline of novel specialty drug candidates
and a mature portfolio of products and projects under license collaborations
with Sanofi, Helsinn Healthcare and Boehringer Ingelheim.

Zealand’s first invented medicine, lixisenatide, a once-daily prandial GLP-1
analogue for the treatment of Type 2 diabetes, is marketed globally outside the
US as Lyxumia® by Sanofi and under regulatory review in the US. The license
collaboration with Sanofi covers also a single-product combination of
lixisenatide and insulin glargine (Lantus®) which is on track for regulatory
submission in the US in Q4 2015 and in the European Union in Q1 2016.

The proprietary pipeline includes; danegaptide for ischemic reperfusion
Injuries in Phase II development; ZP1848 for Short Bowel Syndrome in Phase II
development; and the stable glucagon analogue, ZP4207, in Phase II preparation
both as a single-dose rescue pen for severe hypoglycemia and for multiple-dose
use to treat and control mild to moderate hypoglycemia; as well as several
preclinical peptide therapeutics.

The company is based in Copenhagen (Glostrup), Denmark. For further information
about Zealand’s business and activities, please visit: www,zealandpharma.com or
follow us on Twitter @ZealandPharma