Novonesis AS

Transaction in Own Shares • May 6, 2021

Trading by management and close relations of management

In accordance with article 19 in Regulation (EU) No 596/2014 of 16 April 2014 on market abuse (the Market Abuse Regulation) and commission delegated regulation (EU) 1052/2016 of 8 March 2016, Novozymes reports the following transactions under ISIN DK0060336014, Novozymes B shares under the symbol NZYM B.

Details of the person discharging managerial responsibilities/person closely associated Name Claus Crone Fuglsang Reason for notification +45 3077 8682 Carl Ahlgren

Company announcement No. 25

May 6, 2021

Contact information novozymesIR@novozymes.com

Tobias Cornelius Björklund tobb@novozymes.com

+1 919 702 6144

Position/status	CSO and Executive Vice President, Research & Development	cxal@novozymes.com
Initial notification/	Initial notification
amendment		Ulrik Wu Svare
		+45 3077 3187
Details of the issuer		ulms@novozymes.com

Entity	Novozymes A/S
LEI code	529900T6WNZXD2R3JW38

Details of the transaction(s)

Description:
Financial instrument	Shares
Identification code	ISIN DK0060336014
Nature of the transaction	Exercise of share options (purchase)
Place(s) of transaction(s),
price(s) and volume(s)	Place(s) Price(s) Volume(s)
	Novozymes' custody account 271.20 17,296 shares
Aggregated information	Number of shares: 17,296
	Average price, DKK: 271.20
	Transaction value, DKK: 4,690,675.20
Date of the transaction	2021-05-05 (10:50:25 CET)

About Novozymes

Novozymes is the world leader in biological solutions. Together with customers, partners and the global community, we improve industrial performance while preserving the planet's resources and helping build better lives. As the world's largest provider of enzyme and microbial technologies, our bioinnovation enables higher agricultural yields, low-temperature washing, energyefficient production, renewable fuel and many other benefits that we rely on today and in the future. We call it Rethink Tomorrow. www.novozymes.com

Novozymes A/S CVR number: 10 00 71 27 LEI: 529900T6WNZXD2R3JW38

Novozymes A/S Krogshoejvej 36 2880 Bagsvaerd Denmark

Phone: +45 4446 0000

Details of the person discharging managerial responsibilities/person closely associated

Name Claus Crone Fuglsang

Reason for notification

Position/status	CSO and Executive Vice President, Research & Development
Initial notification/	Initial notification
amendment

Details of the issuer

Entity	Novozymes A/S
LEI code	529900T6WNZXD2R3JW38

Details of the transaction(s)

Description:
Financial instrument	Shares
Identification code	ISIN DK0060336014
Nature of the transaction	Sale of shares
Place(s) of transaction(s),
price(s) and volume(s)	Place(s)	Price(s)	Volume(s)
	See appendix	See appendix	See appendix
Aggregated information	Number of shares: 17,296
	Average price, DKK: 441.79
	Transaction value, DKK: 7,641,125.05
Date of the transaction	2021-05-05 (see appendix for details)

Appendix

Date & Time	Exchange	No. of shares	Price (DKK)
05.May.2021 10:58:04	XOFF	54	442.7
05.May.2021 11:01:45	XOFF	26	442.8
05.May.2021 11:01:45	XOFF	25	442.8
05.May.2021 11:01:45	XOFF	43	442.8
05.May.2021 11:01:49	XOFF	23	442.8
05.May.2021 11:01:49	XOFF	9	442.8
05.May.2021 11:01:52	XOFF	21	442.8
05.May.2021 11:02:22	XOFF	171	442.6
05.May.2021 11:03:57	XOFF	63	442.9
05.May.2021 11:03:57	XOFF	212	442.8
05.May.2021 11:03:58	XOFF	61	442.8
05.May.2021 11:03:58	XOFF	9	442.8
05.May.2021 11:04:51	XOFF	32	442.7
05.May.2021 11:04:51	XOFF	62	442.7
05.May.2021 11:06:06	XOFF	32	442.6
05.May.2021 11:06:06	XOFF	19	442.6
05.May.2021 11:06:06	XOFF	32	442.6
05.May.2021 11:06:06	XOFF	64	442.6
05.May.2021 11:07:51	XOFF	32	442.6
05.May.2021 11:07:51	XOFF	42	442.6
05.May.2021 11:07:51	XOFF	22	442.6
05.May.2021 11:08:56	XOFF	23	442.6
05.May.2021 11:08:56	XOFF	19	442.6
05.May.2021 11:08:56	XOFF	30	442.6
05.May.2021 11:09:55	XOFF	24	442.6
05.May.2021 11:09:55	XOFF	11	442.6
05.May.2021 11:09:55	XOFF	13	442.6
05.May.2021 11:09:55	XOFF	33	442.6
05.May.2021 11:09:55	XOFF	10	442.6
05.May.2021 11:11:37	XOFF	23	442.6
05.May.2021 11:11:37	XOFF	32	442.6
05.May.2021 11:14:55	XOFF	173	442.5
05.May.2021 11:15:02	XOFF	73	442.7
05.May.2021 11:15:47	XOFF	889	442.6
05.May.2021 11:15:49	XOFF	18	442.7
05.May.2021 11:15:49	XOFF	24	442.7
05.May.2021 11:15:49	XOFF	16	442.7
05.May.2021 11:15:49	XOFF	36	442.7
05.May.2021 11:15:49	XOFF	23	442.8
05.May.2021 11:15:49	XOFF	31	442.8
05.May.2021 11:34:32	XOFF	902	441.1
05.May.2021 11:34:37	XOFF	1174	441
05.May.2021 11:34:40	XOFF	90	441

a m

05.May.2021 11:34:40	XOFF	2	441.1
05.May.2021 11:34:40	XOFF	21	441.1
05.May.2021 11:34:40	XOFF	30	441.1
05.May.2021 11:35:02	XOFF	140	441.15
05.May.2021 11:35:10	XOFF	32	441.3
05.May.2021 11:35:10	XOFF	18	441.3
05.May.2021 11:35:10	XOFF	7	441.3
05.May.2021 11:35:10	XOFF	9	441.3
05.May.2021 11:35:10	XOFF	9	441.3
05.May.2021 11:35:10	XOFF	3	441.3
05.May.2021 11:35:10	XOFF	9	441.3
05.May.2021 11:35:10	XOFF	100	441.3
05.May.2021 11:36:05	XOFF	2	441.7
05.May.2021 11:36:05	XOFF	9	441.7
05.May.2021 11:36:58	XOFF	23	441.7
05.May.2021 11:36:58	XOFF	5	441.7
05.May.2021 11:36:58	XOFF	25	441.7
05.May.2021 11:36:58	XOFF	7	441.7
05.May.2021 11:37:45	XOFF	25	441.7
05.May.2021 11:37:45	XOFF	8	441.7
05.May.2021 11:37:45	XOFF	41	441.7
05.May.2021 11:41:13	XOFF	24	441.8
05.May.2021 11:41:13	XOFF	19	441.8
05.May.2021 11:41:13	XOFF	34	441.8
05.May.2021 11:41:13	XOFF	6	441.8
05.May.2021 11:41:13	XOFF	32	442
05.May.2021 11:41:15	XOFF	191	441.9
05.May.2021 11:41:18	XOFF	369	441.95
05.May.2021 11:41:18	XOFF	52	441.7
05.May.2021 11:41:18	XOFF	99	441.7
05.May.2021 11:41:18	XOFF	75	441.7
05.May.2021 11:41:18	XOFF	46	441.7
05.May.2021 11:41:18	XOFF	173	441.6
05.May.2021 11:41:35	XOFF	44	441.4
05.May.2021 11:41:35	XOFF	45	441.4
05.May.2021 11:41:35	XOFF	19	441.4
05.May.2021 11:41:35	XOFF	29	441.4
05.May.2021 11:41:35	XOFF	35	441.4
05.May.2021 11:41:35	XOFF	177	441.4
05.May.2021 11:41:35	XOFF	153	441.4
05.May.2021 11:41:37	XOFF	236	441.4
05.May.2021 11:42:34	XOFF	141	441.4
05.May.2021 11:42:34	XOFF	29	441.5
05.May.2021 11:42:34	XOFF	53	441.5
05.May.2021 11:42:34	XOFF	126	441.4
05.May.2021 11:42:34	XOFF	174	441.3

	×
× ۰.

05.May.2021 11:42:45	XOFF	32	441.1
05.May.2021 11:42:45	XOFF	65	441.1
05.May.2021 11:42:58	XOFF	896	440.5
05.May.2021 11:42:59	9125	174	440.6
05.May.2021 11:43:02	XOFF	40	440.8
05.May.2021 11:43:02	XOFF	45	440.8
05.May.2021 11:43:02	XOFF	61	440.9
05.May.2021 11:43:02	XOFF	55	440.9
05.May.2021 11:43:05	XOFF	28	441
05.May.2021 11:43:05	XOFF	50	441
05.May.2021 11:43:05	XOFF	64	441.1
05.May.2021 11:43:20	XOFF	61	441
05.May.2021 11:43:24	XOFF	29	441.1
05.May.2021 11:43:24	XOFF	53	441.1
05.May.2021 11:43:25	XOFF	25	441.3
05.May.2021 11:43:25	XOFF	38	441.3
05.May.2021 11:45:08	XOFF	24	441.8
05.May.2021 11:45:08	XOFF	12	441.8
05.May.2021 11:45:08	XOFF	11	441.8
05.May.2021 11:45:08	XOFF	36	441.8
05.May.2021 11:45:55	XOFF	32	441.8
05.May.2021 11:45:55	XOFF	66	441.8
05.May.2021 11:46:55	XOFF	6	441.9
05.May.2021 11:46:57	XOFF	26	441.9
05.May.2021 11:46:57	XOFF	66	441.9
05.May.2021 11:46:57	XOFF	10	441.9
05.May.2021 11:48:13	XOFF	23	441.9
05.May.2021 11:48:13	XOFF	30	441.9
05.May.2021 11:49:08	XOFF	53	441.7
05.May.2021 11:15:54	XOFF	17	443
05.May.2021 11:17:08	XOFF	30	442.9
05.May.2021 11:17:08	XOFF	56	442.9
05.May.2021 11:18:08	XOFF	25	442.9
05.May.2021 11:18:08	XOFF	15	442.9
05.May.2021 11:18:08	XOFF	41	442.9
05.May.2021 11:18:34	XOFF	7	442.9
05.May.2021 11:18:34	XOFF	21	442.9
05.May.2021 11:18:34	XOFF	25	442.9
05.May.2021 11:19:14	XOFF	20	443.2
05.May.2021 11:19:14	XOFF	21	443.2
05.May.2021 11:19:26	XOFF	23	443.1
05.May.2021 11:19:26	XOFF	32	443.1
05.May.2021 11:19:36	XOFF	30	443.1
05.May.2021 11:19:43	XOFF	16	443.1
05.May.2021 11:19:43	XOFF	12	443.1
05.May.2021 11:19:43	9125	74	443

	a m
× ۰,

05.May.2021 11:20:32	XOFF	23	443.3
05.May.2021 11:20:32	XOFF	30	443.3
05.May.2021 11:20:33	XOFF	24	443.6
05.May.2021 11:20:33	XOFF	34	443.6
05.May.2021 11:20:33	XOFF	23	443.7
05.May.2021 11:20:33	XOFF	30	443.8
05.May.2021 11:21:24	XOFF	175	443.3
05.May.2021 11:21:33	XOFF	32	443.2
05.May.2021 11:21:33	XOFF	62	443.2
05.May.2021 11:22:07	XOFF	23	443.2
05.May.2021 11:22:07	XOFF	20	443.2
05.May.2021 11:22:07	XOFF	11	443.2
05.May.2021 11:22:07	XOFF	8	443.2
05.May.2021 11:22:07	XOFF	30	443.2
05.May.2021 11:22:07	XOFF	11	443.2
05.May.2021 11:22:21	XOFF	96	443.1
05.May.2021 11:26:52	XOFF	26	442.5
05.May.2021 11:26:52	XOFF	42	442.5
05.May.2021 11:26:53	XOFF	171	442.4
05.May.2021 11:27:28	XOFF	32	442.5
05.May.2021 11:28:41	XOFF	64	442.5
05.May.2021 11:28:41	XOFF	13	442.5
05.May.2021 11:29:20	XOFF	18	442.5
05.May.2021 11:29:20	XOFF	19	442.5
05.May.2021 11:29:20	XOFF	16	442.5
05.May.2021 11:29:20	XOFF	19	442.5
05.May.2021 11:29:20	XOFF	18	442.6
05.May.2021 11:30:10	XOFF	5	442.2
05.May.2021 11:30:10	XOFF	21	442.2
05.May.2021 11:30:10	XOFF	20	442.2
05.May.2021 11:30:10	XOFF	44	442.2
05.May.2021 11:30:10	XOFF	9	442.2
05.May.2021 11:30:38	XOFF	34	442.3
05.May.2021 11:30:37	XOFF	70	442.3
05.May.2021 11:30:56	XOFF	300	441.9
05.May.2021 11:31:00	XOFF	84	441.7
05.May.2021 11:31:00	XOFF	3	441.7
05.May.2021 11:31:00	XOFF	84	441.7
05.May.2021 11:31:06	XOFF	1077	441.55
05.May.2021 11:31:18	XOFF	34	441.7
05.May.2021 11:31:18	XOFF	2	441.7
05.May.2021 11:31:18	XOFF	78	441.7
05.May.2021 11:31:18	XOFF	61	441.7
05.May.2021 11:31:21	XOFF	29	441.8
05.May.2021 11:31:21	XOFF	52	441.8
05.May.2021 11:31:36	XOFF	28	442.2

05.May.2021 11:31:36	XOFF	50	442.2
05.May.2021 11:32:12	XOFF	7	442.2
05.May.2021 11:32:12	XOFF	16	442.2
05.May.2021 11:32:12	XOFF	33	442.2
05.May.2021 11:32:42	XOFF	23	442.4
05.May.2021 11:33:49	XOFF	122	441.95
05.May.2021 11:33:49	XOFF	148	441.95
05.May.2021 11:33:49	XOFF	180	441.95
05.May.2021 11:33:54	XOFF	200	441.8
05.May.2021 11:34:00	XOFF	173	441.6
05.May.2021 11:34:07	XOFF	325	441.5
05.May.2021 11:34:10	XOFF	132	441.45
05.May.2021 11:34:10	XOFF	171	441.4
05.May.2021 11:34:12	XOFF	1400	441.45
05.May.2021 11:34:25	XOFF	23	441.5
05.May.2021 11:34:25	XOFF	30	441.5
05.May.2021 11:34:30	XOFF	141	441.1
05.May.2021 10:51:18	XOFF	53	443
05.May.2021 10:52:07	XOFF	27	443.2
05.May.2021 10:52:07	XOFF	4	443.1
05.May.2021 10:52:07	XOFF	23	443.1
05.May.2021 10:52:07	XOFF	42	443.1
05.May.2021 10:52:52	XOFF	28	443
05.May.2021 10:52:52	XOFF	49	443
05.May.2021 10:52:56	XOFF	175	442.95
05.May.2021 10:53:00	XOFF	30	443
05.May.2021 10:53:00	XOFF	23	443
05.May.2021 10:53:08	XOFF	64	442.8
05.May.2021 10:53:56	XOFF	32	442.8
05.May.2021 10:54:42	XOFF	64	442.8
05.May.2021 10:54:43	XOFF	32	442.9
05.May.2021 10:56:42	XOFF	23	442.8
05.May.2021 10:56:42	XOFF	30	442.8
05.May.2021 10:57:01	XOFF	32	443
05.May.2021 10:57:01	XOFF	83	442.8