OXFORD CANNABINOID TECHNOLOGIES HOLDINGS PLC

Proxy Solicitation & Information Statement • Oct 27, 2021

Oxford Cannabinoid Technologies Holdings PLC Additional Holders:

The Chairman of Oxford Cannabinoid Technologies Holdings PLC invites you to attend the Annual General Meeting of the Company to be held at the offices of Penningtons Manches Cooper LLP, 125 Wood Street, EC2V 7AW on 24 November 2021 at 10.00 a.m.

Please detach this portion before posting this proxy form.

Form of Proxy – Annual General Meeting to be held on 24 November 2021

Shareholder Reference Number

To be effective, all proxy appointments must be lodged with the Company's Registrars at: Computershare Investor Services PLC, The Pavilions, Bridgwater Road, Bristol BS99 6ZY by 22 November 2021 at 10.00 a.m.

Explanatory Notes:

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• 1. Every holder has the right to appoint some other person(s) of their choice, who need not be a shareholder, a proxy or proxies to exercise all or any of his rights, to attend, speak and vote on their behalf at the meeting. If you wish to appoint a person other than the Chairman, please insert the name of your chosen proxy holder in the space provided (see reverse). If the proxy is being appointed in relation to less than your full voting entitlement, please enter in the box next to the proxy holder's name (see reverse) the number of ordinary shares of £0.01 each in the capital of the Company ("Ordinary Shares") in relation to which they are authorised to act as your proxy. If returned without an indication as to how the proxy shall vote on any particular matter, the proxy will exercise his discretion as to whether, and if so how, he votes (or if this proxy form has been issued in respect of a designated account for a shareholder, the proxy will exercise his discretion as to whether, and if so how, he votes). Appointment of a proxy does not preclude you from attending the meeting and voting in person. If you have appointed a proxy and attend the meeting in person and vote, your proxy appointment will automatically be terminated.
• 1. To appoint more than one proxy, an additional proxy form(s) may be obtained by contacting the Registrar's helpline on 0370 703 0342 or you may photocopy this form. Please indicate in the box next to the proxy holder's name (see reverse) the number of Ordinary Shares in relation to which they are authorised to act as your proxy. Please also indicate by marking the box provided if the proxy instruction is one of multiple instructions being given. All forms must be signed and should be returned together in the same envelope.
• 1. The 'Vote Withheld' option overleaf is provided to enable you to abstain on any particular resolution. However, it should be noted that a 'Vote Withheld' is not a vote in law and will not be counted in the calculation of the votes 'For' and 'Against' a resolution.
• 1. Pursuant to Regulation 41 of the Uncertificated Securities Regulations 2001, entitlement to attend and vote at the meeting and the number of votes which may be cast thereat will be determined by reference to the Register of Members of the Company at 6.30 p.m. on 22 November 2021 or if the meeting is adjourned, no later than 48 hours before the time of any adjourned meeting, excluding non-working days. Changes to entries on the Register of Members after that time shall be disregarded in determining the rights of any person to attend and vote at the meeting.
• 1. To appoint one or more proxies or to give an instruction to a proxy (whether previously appointed or otherwise) via the CREST system, CREST messages must be received by the issuer's agent (ID number 3RA50) no later than 10.00 a.m. on 22 November 2021 or if the meeting is adjourned, no later than 48 hours before the time of any adjourned meeting, excluding non-working days. For this purpose, the time of receipt will be taken to be the time (as determined by the timestamp generated by the CREST system) from which the issuer's agent is able to retrieve the message. The Company may treat as invalid a proxy appointment sent by CREST in the circumstances set out in Regulation 35(5)(a) of the Uncertificated Securities Regulations 2001.
• 1. The above is how your address appears on the Register of Members. If this information is incorrect please ring the Registrar's helpline on 0370 703 0342 to request a change of address form or go to www.investorcentre.co.uk to use the online Investor Centre service.
• 1. Any alterations made to this form should be initialled.

Kindly Note: This form is issued only to the addressee(s) and is specific to the unique designated account printed hereon. This personalised form is not transferable between different: (i) account holders; or (ii) uniquely designated accounts. The Company and Computershare Investor Services PLC accept no liability for any instruction that does not comply with these conditions.

All Named Holders

Form of Proxy

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Please complete this box only if you wish to appoint a third party proxy other than the Chairman. Please leave this box blank if you want to select the Chairman. Do not insert your own name(s).

I/We hereby appoint the Chairman of the Meeting OR the person indicated in the box above as my/our proxy to attend, speak and vote in respect of my/our full voting entitlement* on my/our behalf at the Annual General Meeting of Oxford Cannabinoid Technologies Holdings PLC to be held at the offices of Penningtons Manches Cooper LLP, 125 Wood Street, EC2V 7AW on 24 November 2021 at 10.00 a.m., and at any adjourned meeting. 8

* For the appointment of more than one proxy, please refer to Explanatory Note 2 (see front).

Please mark here to indicate that this proxy appointment is one of multiple appointments being made.

*

Please use a black pen. Mark with an X inside the box as shown in this example.

		For	Against	Vote Withheld
	Ordinary Resolutions
1.	To receive and adopt the annual accounts and reports for the financial period ended 31 May 2021.
2.	To receive and approve the Directors' remuneration report for the financial period ended 31 May 2021.
3.	To re-elect Charanjit Cheryl Dhillon as director of the Company.
4.	To re-elect Karen Lowe as director of the Company.
5.	To re-elect Dr John Lucas as director of the Company.
6.	To re-elect Indraneil Mahapatra as director of the Company.
7.	To re-elect Bishrut Mukherjee as director of the Company.
8.	To re-elect Julie Patricia Pomeroy as director of the Company.
9.	To re-elect Gavin Hilary Sathianathan as director of the Company.
	10. To re-elect Clarissa Ann Sowemimo-Coker as director of the Company.
	11. To re-appoint Moore Kingston Smith LLP as auditors of the Company.
	12. To authorise the Directors to fix the remuneration of the auditors of the Company.
	13. To authorise the Directors to allot ordinary shares and relevant securities, pursuant to Section 551 of the Companies Act 2006.
Special Resolutions
	14. To authorise the directors to disapply pre-emption rights (general authority).
	15. To authorise the directors to disapply pre-emption rights (additional authority).
	16. That a general meeting other than an annual general meeting may be called on not less than 14 clear days' notice.

I/We instruct my/our proxy as indicated on this form. Unless otherwise instructed the proxy may vote as he or she sees fit or abstain in relation to any business of the meeting.

Signature Date

DD/MM/YY

In the case of a corporation, this proxy must be given under its common seal or be signed on its behalf by an attorney or officer duly authorised, stating their capacity (e.g. director, secretary).

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