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130_10-k_2008-04-09_8bbface8-f4d8-428a-9835-6f0bcf884259.pdf

Annual Report

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Uncover the Hidden

IFRS Change IFRS IFRS
2007 over 2006 2006 2005
Revenue TEUR 54,444 + 8% 50,378 41,792
Return on revenue before tax 9% - 4% 9% 5%
Profit for the year TEUR 1,948 - 12% 2,221 1,590
Profit before tax (EBT) TEUR 4,921 + 4% 4,748 2,215
Interest TEUR -767 - 4% -796 -667
EBIT TEUR 5,688 + 3% 5,544 2,882
Depreciation and amortization TEUR -3,731 - 18% -4,537 -3,912
EBITDA TEUR 9,419 - 7% 10,081 6,794
Earnings per share EUR 0.62 - 13% 0.71 0.51
Cash flow from operating activities TEUR 6,631 + 45% 4,561 3,531
Tax rate 56% + 66% 34% 31%
Shareholders' equity TEUR 36,491 + 0% 36,329 34,955
Equity ratio 54% - 5% 57% 52%
Total assets TEUR 67,587 + 5% 64,174 66,997
Book value per share EUR 11.61 + 0% 11.59 11.28
Staff Persons 327 + 12% 291 247
Number of shares as of Dec. 31
(excl. own shares) Item 3,142,290 0% 3,130,526 3,120,511
Dividends EUR 0.25* 0% 0.25 0.15

The specified key indicators refer to earnings for continuing operations with the exception of the year's net income or shortfall and results per share.

* Dividend to be recommended by the company to the annual general meeting on June 11, 2008

Group Management Report 13
10
Letter to Shareholders 6
2007 Milestones 4
The Share
Staff 32
Marketing and Public Relations 34
Environment and Safety 35
Quality Management 36
Consolidated Financial Statements
of the Eckert & Ziegler Group
39
Notes to the Group Financial
Statements
44
Corporate Governance Report 80
Supervisory Board Report 82
Parent Company's Financial
Statements of Eckert & Ziegler
Aktiengesellschaft
83
Glossary 86
Corporate Structure 88
Financial Calendar 90
Imprint 90

Contact 90

Notes to the English translation

This English translation of Eckert & Ziegler AG annual report has been compiled with care and diligence. However, the relevant version is in all cases, including errors and omissions, the German original. Further, since the annual report is a technical document, and the German grammar is quite different from the English one, some of the translations may sound awkward. We tried to eliminate clumsy passages as much as possible, but apologize if we failed to do so completely.

Konsoldierte Gewinn- und Verlustrechnungen 2007 Milestones

January

n Forschergarten (Researchers Garden; www.forschergarten.de), the natural science pre-school program that was initiated by Eckert & Ziegler AG, is honored as a "Ausgewählter Ort im Land der Ideen 2007" (2007 Selected Site in the Land of Ideas).

n Eckert & Ziegler BEBIG receives a large-scale follow-up contract from Venezuela to supply innovative tumor radiation systems of the MultiSource® type. The total volume amounts to 1.6 million US dollars.

March

n At the annual results press conference held on March 29, Eckert & Ziegler reports record revenue for 2006, with the annual revenue threshold of

EUR 50 million being exceeded for the first time. Compared with the previous year, the dividend per share rises by 67%.

2004 2005 2006 35,533 41,792 50,378

n Positron emission tomography (PET) will in future be capable of being prescribed as an approved medical method for determining the tumor stage and detecting the reoccurrence of non-small-cell lung cancer and also in characterizing lung nodules for avoiding operative procedures. As a result of the signal effect for establishing this unique investigation method, a consid-

n The seventh MedTech Day takes place in Frankfurt in collaboration with the Deutsche Börse, the DVFA (German Association of Financial Analysts), the Landesbank Baden-Württemberg and the Spectaris industrial federation.

May

June

n The renowned French institute for radiation therapy, the Institut Curie in Paris, again extends its existing cooperation contract with Eckert & Ziegler AG to supply prostate implants. The contract is worth roughly EUR 2 million.

erable rise in the numbers of investigations is expected.

n For the first time, a tumor radiation machine ("Afterloader") of the MultiSource® type is installed in India. The Mahatma Ghandi Memorial Hospital in

Bhimavaram will in future work with this machine, which is equipped with a long-life cobalt source.

July

n Eckert & Ziegler AG can look back on ten years of successful work and the company celebrates its anniversary in Berlin with guests from the worlds of politics, business, and culture.

n Eckert & Ziegler acquires the Bonn radiopharmacy producer MC Pharma and further consolidates its market position as a manufacturer of radiopharmaceuticals for new imaging methods in nuclear medicine.

The cyclotron which is acquired is used to produce contrast media, also referred to as PET tracers, which are used in positron emission tomography (PET) to diagnose cancer.

n In order to create closer ties with customers, be more efficient and optimize the flows of information, the radiopharmacy segment is restructured. The

cyclotron division is established and the responsibilities for contrast media throughout Europe are centralized.

n The Californian subsidiary Eckert & Ziegler Isotope Products Inc. (IPL) presents the new gallium-68 generator IGG100 at the 20th Congress of the European Association of Nuclear Medicine.

n The European Association of Nuclear Medicine (EANM) and Eckert & Ziegler offer a joint award to promote research work among young, talented nuclear medicine researchers. In the coming years, the intention is

that the EANM Eckert & Ziegler Abstract Award will considerably boost the profile of Eckert & Ziegler in international expert circles within nuclear medicine.

n Eckert & Ziegler Eurotope GmbH, a specialist in systems and automation technology for producing radiopharmaceuticals, presents improved synthesis modules for marking peptides with gallium-68. The devices utilize a production process with improved process

parameters and make it possible to produce a whole range of gallium peptides. The field of application of Modular Lab is therefore expanded to include a class of materials which is currently being researched intensively by many users of nuclear medicine.

October

November

December

Letter to Shareholders

Dear Friends of Eckert & Ziegler,

In 2007 our company again made good progress. In organic terms and adjusted for exchange rate fluctuations, the business volume grew by roughly 10 percent to a new record high of EUR 55 million. Over the last five years, the Group has now managed to increase its sales volume at an average annual growth rate of about 14% – without dilution and a stable equity ratio. In addition, the purchase of another cyclotron company in 2007 and the merger of the prostate cancer implant business with IBt has laid the foundations for growth in the future. We expect to surpass the EUR 70 million sales revenue level shortly. With extensive investments in infrastructure and a pipeline full of new products, Eckert & Ziegler should be positioned well for the future.

Along with the sales also earnings developed well in 2007. Although the net profit for the year is nominally 13% lower than in the previous one, this is exclusively due to a cash neutral book loss resulting from a change in the German tax laws. If one excludes this effect, the year under review displays growth of 25% from EUR 0.71 to EUR 0.89 per share. In the operational capital flow, this is reflected – literally – in hard cash: the self-financing capacity rose by EUR 2 million to EUR 6.5 million and was 44% above the level of the previous year. For the first time in five years, the Group was able to largely conserve its liquidity reserves and refrain almost entirely from selling securities.

In spite of the organic growth, the renewed dividend and the takeover of a rival company, the Group's key balance sheet figures remained solid in the year under review. The equity ratio remained stable within its normal variations, reaching again a high level of 54%. The leverage ratio fell slightly. Productivity rose. The innovative strength, measured by the level of sales from new products, that is, by those that are less then three years in the Group's product portfolio, remained high. Almost a third of anything the Company sold in 2007 fell into this category. In terms of the key economic parameters, the fiscal year was without doubt a success.

Not only the numbers looked good. In 2007 also the strategic position of the company improved. Particu-

larly outstanding achievements were the advances made in the new Radio-pharmaceuticals segment, where considerable leaps in sales and improved profitability were recorded. The Executive Board is convinced that nuclear medicine imaging processes, and here in particular positron emission tomography (PET), will become increasingly important in the future, and that the Group is well advised to become actively involved in this area.

One of the reasons for the growth seen in nuclear medicine is that more and more hybrid devices are being developed and marketed in which different imaging processes – and in particular PET – are combined with one another in one device. The benefits of these multi-modality devices are that they provide, in high resolution, graphically outstanding images which can be interpreted intuitively and can be shown and analysed on a computer in all possible perspectives and sections. This gives doctors a completely new tool for diagnosis and follow-up checks and, in the best-case scenario, they no longer need to call in specialists to answer specific questions.

The new hybrid devices are still expensive and confined at present to university hospitals and other early pioneering organizations, but their advantages will quickly ensure that hospitals acquire such devices on a wide-scale basis. In order to tap into their full potential, suppliers will then be needed to provide the cor-

responding radioactive contrast media. Eckert & Ziegler is well placed to cater for this need. By acquiring Eckert & Ziegler EURO-PET Köln/ Bonn, we were able in the year under review to add to our network even another production centre. It is located in the densely populated Ruhr area and already has a well established customer base there.

Our commitment to nuclear imaging not only extends to contrast media. Eckert & Ziegler is also developing automatic synthesis devices that can be used for a decentralised production of radiopharmaceuticals. Contrary to conventional drugs, contrast media used for positron emission tomography cannot be centrally manufactured and distributed; they must instead be reproduced every day in local cyclotrons. These creates a need for reliable and inexpensive devices that meet the requirements of pharmaceutical Good Manufacturing Practise. Eckert & Ziegler hence becomes a partner in the distribution of new contrast media by enabling drug companies to bring their innovations to the clinic.

"Uncover the Hidden", the motto of the Radiopharmaceuticals segment and this business report, could also serve as a caption describing our most recent transaction. It brought together the implant division of Eckert & Ziegler with the ones of our former Belgian competitor International Brachytherapy (IBt). As a result of the transaction, IBt has become Europe's

most important manufacturers of implants for the treatment of prostate cancer, and Eckert & Ziegler is now IBt's by far biggest shareholder. The Executive Board is convinced that the combined entity can be much more profitable then the two units each on its own. Also, by concentrating the prostate cancer activities in a listed medical technology company, there is a good chance that they will be free from the valuation markdowns that have affected Eckert & Ziegler AG in the past. At the time that this business report went to print, BEBIG's implants business was worth EUR 24 million, and thus not much less than the market capitalization of the Group as a whole.

We are optimistic that this promising outlook together with the results from the last fiscal year will also benefit shareholders in Eckert & Ziegler AG and we would be delighted as always if you continue to show your kind loyalty to us as a result.

Yours

Dr. Andreas Eckert Chief Executive Officer

The Executive Board of the Eckert & Ziegler AG: Dr. Andreas Eckert, Dr. Edgar Löffler and Dr. André Heß (left to right)

The combination of state-of-the-art technology and radioactivity allows many things to become visible which would remain hidden without them: The tiniest tumors and Parkinson's disease. Natural resources in the earth. Objects that are not meant to be transported in an airplane.

Uncoverthe Hidden

For us, uncovering the hidden also means systematically cultivating the talents of our employees and consistently being aware of the wishes of our customers.

Positron emission tomography, PET for short, is one of the functional imaging processes. With high spatial resolution, it makes complicated metabolic processes in the human body visible – unlike traditional methods (e.g. MRT, CT) – and

makes it possible to pinpoint cancer cells or provides answers to highly complex neurological questions.

A chemical compound (e.g. glucose, a neurotransmitter, antibody) acts as a messenger substance, is linked

(marked) with a weakly radiating radionuclide (e.g.[18F] fluorine, [11C] carbon) and injected into the body. The molecule docks on a cell in which a specific metabolic process takes place – for example in a cancer cell. The PET scanner now detects the

"glowing" radionuclide, allowing imaging and quantification of the desired metabolic process. The physician carrying out the treatment can now see very clearly where any tumor may be located.

PET/CT scan of a brain metastasis The Share

Key data on the Eckert & Ziegler share

International Securities Identification Number (ISIN) DE0005659700

Security identification number (WKN) 565 970

Stock exchange symbols EUZ (Deutsche Börse) EUZ (Bloomberg) EUZG (Reuters)

Stock exchange sector Prime Standard, Frankfurt

All-share indexes

Prime All Share Technology All Share German Entrepreneurial Index (GEX)

Industry-specific index Prime Sector: Pharma & Healthcare Industrial group: Medical Technology

Nominal share capital (Dec. 31, 2007) EUR 3,250,000

Owner bearer shares (Dec. 31, 2007) 3,250,000 units

Share price (Dec. 31, 2007) EUR 9.86

Market capitalization (Dec. 31, 2007) EUR 32.05 million

Highest/lowest price in 2007 EUR 13.01 / EUR 9.80

Investor relations contact of the Eckert & Ziegler Group

Thomas Scheuch Robert-Rössle-Str. 10 13125 Berlin Germany Tel. +49 30 941084-139 Fax +49 30 941084-112 [email protected] www.ezag.de

Shares in Eckert & Ziegler AG commenced trading on the stock exchange on May 25, 1999. Since then, they have been quoted on the Frankfurt Stock Exchange

and on all the German regional exchanges and they are approved for trading on the fully electronic XETRA® trading system. They are traded under the internationally unique, 12-digit security identification number DE0005659700, although the share is also still identified by its former security identification number (WKN) 565970.

In a capital increase, the company's ordinary share capital was increased to EUR 3,250,000 on June 2, 2000. The share capital is divided into 3,250,000 bearer shares with no par value which each confer one vote at the annual general meeting.

As from February 20, 2003, Eckert & Ziegler AG shares have been listed under the Prime Standard. The companies listed in this segment are subject to particularly high international transparency standards which even exceed the prescribed statutory publicity requirements.

In March 2003, Eckert & Ziegler AG acquired 320,000 of its own shares as part of a share buy-back program. These shares have so far largely been used for financing acquisitions and for servicing employee stock options. The capital gains realized from the transactions have all been transferred to the capital reserve for own shares. The company reported that it held 106,835 of its own shares on December 31, 2007.

Since January 3, 2005, shares in Eckert & Ziegler AG have been used to calculate the German Entrepreneurial Index (GEX). This index lists Prime Standard companies in which substantial stock options are held by the founders or the management.

Movements in the share price/earnings per share and proposed dividend

In the fiscal year which has just elapsed, the share recorded a loss in value of approx. 19% compared with the previous year. The company's market capitalization fell by EUR 7 million to EUR 32 million compared with the equivalent date the previous year.

The earnings per share are calculated by dividing the Group's annual net profit by the average number of shares in circulation during the fiscal year. In the year under review, the Eckert & Ziegler Group recorded Group earnings per share of EUR 0.62.

The Executive Board and Supervisory Board propose to the Annual General Meeting to be held on 11 June 2008 that a dividend of EUR 0.25 per share be paid for fiscal year 2007. Based on the end-of-year share price of EUR 9.86, this produces a dividend yield of 2.5%.

Investor relations

In 2007, Eckert & Ziegler again endeavored to provide shareholders, investors and financial analysts with prompt and detailed information about the major developments within the company. The main tools used for this were the announcements which have to be made to the stock exchange, press releases and quarterly reports. They were published in German and English and, where appropriate, supplemented with telephone conferences open to the public. In addition, at the annual results press conference in March, the "Medtech Day" industry get-together in the spring, the annual general meeting in May and the German Equity Capital Forum in the autumn, the Executive Board personally presented new developments and, together with staff from the Corporate Communication department, was available all year round to answer any enquiries or receive visits from interested parties.

The Share

0.00 EUR 2002 0.00 EUR 2003 0.25 EUR 2004 0.15 EUR 2005 0.25 EUR 2006 0.25 EUR* 2007

Dividend payment byEckert & Ziegler AG * Proposal to the annual general meeting

Shareholder structure Dec. 31, 2007 (in%)

n Eckert Consult GmbH 37.9
n Jürgen Ziegler 4.8
n Eckert & Ziegler AG 3.3
n Free float 54.0

Our customers need to be able to rely on our products being delivered on time every single day. Throughout the world. Whether they are for I-125 seed implantations or PET/CT diagnoses. Although this presents complications with radioactive products

that have low half lives, it is achievable. A large network is required, extending from complex logistics right through to complicated approval

procedures. We take care of all the things the customer does not need to see and ensure that everything works smoothly.

The company 14
Legal conditions 14
Main product groups and markets 16
Business development 2007 17
Earnings position 18
Work productivity 18
Development of the segments 19
Financial position and net assets 21
Cash flow 22
Research & development 23
Opportunities and risks 25
Post balance sheet events 28
Outlook 28
Remuneration report 29

Group Management Report

The company

Top: Radiopharmaceutical F-18 fluorodeoxyglucose in dispatch units

Center: Eye applicators for ophthalmological applications

Bottom: Transport cartridges for iodine-125 implants

Eckert & Ziegler is an internationally active specialist in radioactive applications in medicine, science and industry. The company's core expertise includes the handling and processing of low level radioactive materials in production facilities which are approved and specially equipped for the purpose in Europe and the United States. In addition, Eckert & Ziegler focuses on the development and production of synthesis equipment for producing radiopharmaceuticals and medical products for treating cancer.

In the international markets in which Eckert & Ziegler operates, there are relatively few competitors. Eckert & Ziegler has no direct competitor offering such a broad range of products because the company's competitors only cater for specific market niches. This situation is unlikely to change in the future because in order to enter the market a competitor would first have to meet demanding conditions to obtain legal approval.

The Group operates its business through subsidiaries which are assigned to three segments. These segments are aligned to various customer groups. Another segment which represents the costs and revenues of the Berlin holding company is not actively involved in operations.

The Therapy segment's products are aimed at radiation therapists, a group of physicians specializing in the treatment of cancer through radiation. The production facilities and management headquarters for the segment are in Berlin. The most important products are small radioactive implants for treating prostate cancer based on iodine-125 (known as "Seeds") and tumor radiation equipment based on cobalt-60 (known as "Afterloaders").

The Nuclear Imaging and Industry segment provides physicists, engineers, and medical physicists with radioactive components for imaging processes, scientific applications, quality assurance and other purposes related to measurement. Management headquarters and the main production facilities are in Los Angeles, California.

Radiopharmaceuticals with sites in Berlin, Bonn and Milan is the Group's newest and fastest-growing segment. The products in this segment comprise radioactive contrast media for positron emission tomography (PET) and synthesis modules for producing radiopharmaceuticals. The equipment is applied both in practice in diagnostics in nuclear medicine and in research.

The markets of the three operative segments are only loosely interconnected; each has its own business cycle and distinctive characteristics. In addition, there are national differences in respect of the general business conditions. This is particularly the case with medical products – the intensity and dynamics of demand are very much dependent on the specifics of particular national health systems and on the presence of local competitors.

Legal conditions

Eckert & Ziegler Strahlen- und Medizintechnik AG is a joint-stock corporation with head office in Germany. The corporation's nominal capital of EUR 3.25 million is divided into 3.25 million owner bearer shares. Each share entitles the holder to one vote and is decisive in determining the share of profit.

Dr. Andreas Eckert owns a total of 1,232,456 shares directly and indirectly and therewith 37.92% of the voting rights through the holding company Eckert Consult Strategieberatung und Kapitalbeteiligungsgesellschaft mbH.

The shareholders of the corporation exercise their rights at the Annual General Meeting. Each share entitles the holder to one vote. Shares with multiple voting rights, preferential voting rights or maximum voting rights do not exist.

The Supervisory Board monitors and advises the Executive Board management. It consists of six members who are elected by the Annual General Meeting. Company founders Dr. Andreas Eckert and Jürgen Ziegler have the statutory right to appoint one member each to the six-member appointed Supervisory Board.

On May 30, 2006, the Executive Board was authorized by an Annual General Meeting resolution with the approval of the Supervisory Board to increase the company's nominal capital through June 30, 2009 by up to EUR 1,625,000 by issuing a maximum of 1,625,000 owner bearer shares for cash and/or noncash contributions (authorized capital).

Furthermore, on April 30, 1999, the Executive Board was authorized by an Annual General Meeting resolution with the approval of the Supervisory Board to carry out a conditional capital increase provided for in the company's articles of incorporation by up to another EUR 300,000 split into a maximum of 300,000

owner bearing shares (authorized but unissued share capital). The conditional capital can be used to service share option owners who take advantage of the company's share options.

A resolution of the Annual General Meeting of June 12, 2007 authorizes the Executive Board to purchase own shares for purposes other than securities trading by December 11, 2008 for a maximum share of 10% of nominal capital.

The Executive Board manages the company and represents it to third parties. The Executive Board consists of one or more people who, in accordance with paragraph 84 of the Stock Companies Act, are appointed by the Supervisory Board for a maximum term of office of five years. It is permitted to repeat or extend term of office, in each case for a maximum of five years. This again requires a Supervisory Board proposal, which can be composed one year before expiry of the term at the earliest. The Supervisory Board can appoint members of the Executive Board to the position of Chief Executive Officer and Deputy Chief Executive Officer.

The Supervisory Board can revoke appointment to the Executive Board and the appointment of the Chief Executive Officer if there is sufficient cause. This could be due, for example, to a serious breach of duty, an inability to manage properly, or a vote of no confidence by the Annual General Meeting.

The articles of incorporation contain basic regulations on the make-up of the company. According to paragraph 179 of the Stock Companies Act, a change to these articles can only be realized by the Annual General Meeting passing a resolution to that effect with a majority of at least three-quarters of the nominal capital represented during the resolution vote.

There are no substantial agreements related to a change of company control as pertains to a takeover offer. Furthermore, there are no compensation agreements with members of the Executive Board or employees in the event of a takeover offer.

Quality control on the starting material for I-125 implants

Main product groups and markets

Production line for I-125 implants

Within its three operative segments, the Group makes a distinction between 11 main product groups in total. Each of these product groups has its own particular characteristics when it comes to the structure of the consumer base, the competition situation, and the geographical focus. The main product groups are as follows:

Therapy segment

    1. Implants for treating prostate cancer
    1. Tumor radiation equipment
    1. Therapy accessories
    1. Ophthalmological products
    1. Other therapy products

Nuclear Imaging and Industry segment

    1. Radioactive components for industrial applications
    1. Radiation sources for nuclear imaging
    1. Calibration and measurement sources
    1. Raw isotopes and other products

Radiopharmaceuticals segment

  1. Radiodiagnostics and other products 11. Synthesis modules

In terms of sales, in 2007 the biggest main product groups were as follows: 1. the radioactive components for industrial measurement systems, 2. the implants for treating prostate cancer, 3. the radiation sources for nuclear imaging, 4. the radiodiagnostics and 5. the tumor radiation equipment. As in previous years, the five biggest main product groups

accounted for roughly three-quarters of sales, a total of approx. EUR 40 million. The other six main product groups accounted for the remaining 25% of Group sales.

As the markets for the main product groups are only loosely linked to one another and appeal to different users and regions, the Group considers that it has a relatively broadly diversified product base despite specializing in radioisotopes.

Competition situation

The following competition situation essentially applies in respect of the five most important product groups:

n In the three most important product groups in the Nuclear Imaging and Industry segment (group nos 6, 7 and 8 above), Eckert & Ziegler has been well positioned in the market for quite some time, with each product group enjoying a world market share of at least one third. This position was maintained or improved in the period under review. Although some niches in this area showed impressive growth rates, the market as a whole, whose volume today is roughly EUR 50–75 million, developed at only about the same pace as the global GDP growth.

Business development 2007

n With implants for treating prostate cancer (group no. 1 above), Eckert & Ziegler's world market share is lower because the Group offers its products only in Europe. North America in particular is home to competitors whose volume of production is much higher; consequently, it can be assumed that production costs per product are lower. However, this advantage is offset by formidable approval procedures, high transport costs, and complex logistics, all of which makes it difficult for them to benefit from their volume advantages outside of North America. Eckert & Ziegler thus considers itself to be competitively well positioned in Europe, where its market share is at least one third of the total market. During the year under review, this situation has remained unchanged.

The European market for implants for treating prostate cancer is worth EUR 25–40 million and has enjoyed double-digit percentage growth rates in the last three years.

n Radiodiagnostics and other products (category no. 11 above) are primarily the sugar fluorodeoxyglucose (FDG) which is radioactively labeled with fluorine-18. It is used at approx. 200 hospitals throughout Europe in positron emission tomography (PET) to diagnose cancers. According to information provided by the market research company Medical Options, Eckert & Ziegler was the second-largest supplier of this contrast medium in Europe as early as 2006, with regional focuses in Germany, Italy, Poland, and Luxembourg. The Executive Board does not anticipate the rankings to have changed in the year under review and considers Eckert & Ziegler to be the market leader in Germany.

The purchase of an additional cyclotron, the former MC Pharma (now: Eckert & Ziegler EURO-PET Köln/ Bonn GmbH), significantly increased Eckert & Ziegler's production capacity and market volume in 2007.

n With tumor radiation equipment (group no.3 above), which was added to the portfolio three years ago, Eckert & Ziegler's share of the world market is still rather low but is growing much faster than the market as a whole. The main sales markets were in Russia, South America, Asia, and the Middle East. With tumor radiation equipment based on isotope technology and accompanying services, annual global sales are today estimated at EUR 80–120 million.

The volume of business of the Eckert & Ziegler Group again increased in 2007 and rose nominally by roughly 8% from EUR 50.4 to 54.4 million. Thus, in the last four years since 2004, the Group has increased its sales by approx. 53%. Since 2003, the Group has grown on average by roughly 14% a year.

In the figures adjusted to take account of exchangerate effects, the increase in 2007 was in fact even greater than 8% because the falls in the exchange rate of the American dollar resulted, in the Nuclear Imaging and Industry segment, in considerably lower levels of sales when converted. If the dollar exchange rate for 2006 were also applied to 2007, the earnings from sales in 2007 would be around EUR 2.0 million and total Group sales would have been EUR 56.4 million and thus 12% higher than in the previous year.

If one wants to assess the Group's organic growth, the sales which appear in the annual accounts from the acquisition of the Bonn-based company MC Pharma must be deducted from these sales figures. They accounted for roughly EUR 0.9 million. In real and organic terms, i.e. disregarding the changes in the exchange rate with the American dollar and the effects of company purchases, the growth rate for Group sales in 2007 corresponded to roughly 10%, and therefore the rate that Eckert & Ziegler was already able to achieve organically from 2005 to 2006.

As expected, in the year under review, the main driver of growth was the Radiopharmaceuticals segment, which increased by roughly EUR 3 million to EUR 9 million. The Therapy segment grew by EUR 1 million from EUR 20 million to EUR 21 million; by contrast, in the Nuclear Imaging and Industry segment sales remained at the previous year's level of EUR 25 million because of the unfavorable dollar exchange rates. When adjusted to take account of the exchange rate, sales in the segment rose by approx. 7%.

In 2007, Europe including Russia accounted for a total of EUR 31 million of sales, which corresponded to an increase of EUR 5 million compared with the previous year. The Euro zone and neighboring regions have therefore become more important for Eckert & Ziegler and now account for approx. 56% of Group sales (previous year: 52%). The most important consumer countries were Germany with EUR 10 million and France with EUR 8 million. However, in 2007 the biggest sales market for Eckert & Ziegler's products was again the United States where goods worth EUR 18 million were invoiced (predominantly in USD).

Catalytic reaction furnace

Their value equated to roughly a third of total Group revenue and was roughly half a million euros above the level of the previous year. The Group's dependence on exchange rates therefore diminished slightly in 2007, but remained high.

Main customer risk: In the year under review, the Group's five biggest customers accounted for total sales worth EUR 5 million, i.e. roughly 9% of total output. Eckert & Ziegler's customer base remained widespread in 2007.

Earnings position

Group earnings of EUR 2.2 million were 12% below earnings for 2006 (EUR 2.5 million). In a two-year comparison, earnings per share (undiluted) fell by 13% and in a comparison with the forecast published by the Group management at the start of the year by EUR 0.28 per share. The reason for the difference was essentially a special effect which could not have been foreseen for the planning period arising from the business tax reform passed by the German Bundestag in spring 2007. This resulted in a reassessment of the Group's deferred taxes and thus in nonpayable value adjustments amounting to EUR 0.27 per share. The value adjustments are detailed in the Group profit and loss account in the row taxes from income and earnings.

Without the special effect resulting from the business tax reform, profit would have been around EUR 2.8 million and therefore EUR 0.89 per share as forecast. It would thus have increased by 25% compared with the previous year (EUR 0.71). A substantial part of this improvement is down to the fact that in the year under review no special amortization was required for development projects which were dropped. In the previous year, they had reduced revenue by EUR 0.6 million.

By contrast, the sales figures, which were up EUR 4.0 million in the year under review, did not result in an increase in revenue. A cost block which rose disproportionately relative to sales again canceled out the increased gross profit margin, which meant that the operating result of EUR 6.0 million attained roughly the same (high) level as the previous year (EUR 5.9 million). The high cost block was due in small part to distribution costs which rose at a disproportionate rate, and otherwise to special revenue that failed to materialize. In the previous year, the latter contributed EUR 1.3 million to the operating result and in the year under review it disappeared completely.

In the case of profit before tax and minorities, the Group result for 2007 was EUR 4.9 million, an increase of 4% over the previous year's result (EUR 4.7 million). With roughly the same burden of interest (EUR 0.8 million) as in 2006, this resulted in EBIT of EUR 5.7 million in 2007. In relation to sales, this equates to an EBIT margin of approx. 10%.

Compared with the previous year, earnings before interest, taxes, depreciation and amortization (EBITDA) fell by 7% to EUR 9.4 million. This was caused by amortization that fell by EUR 0.9 million to 3.7 million compared with the previous year. This resulted from the fact that in 2007 in the Therapy segment a series of capital-intensive production lines became entirely self-financing. In addition, 2006 was a year with a particularly high amortization volume which stands out from the trend seen over previous years. By contrast, the values for 2005 and 2004, namely EUR 3.9 million and 3.7 million, correspond roughly to the 2007 value stated above.

Work productivity

Work productivity, calculated as sale per employee, fell in the year under review, with an average number of 312 employees and sales of EUR 54.4 million, by 5% to EUR 174,000 per employee, and therefore back to the value recorded in 2005. The main reason for this was the drop in work productivity in the Nuclear Imaging and Industry segment as a result of the exchange rate. If instead of the nominal sales figures (EUR 54.4 million) one uses those sales figures that would have been achieved had exchange rates remained constant (EUR 56.4 million, see above), this results in Group productivity of EUR 181,000 per employee and therefore almost exactly the previous year's value.

Stagnation, although better than a drop, is of course not satisfactory. However, in mitigation it should be stated that one reason for the stagnation in productivity growth in the Group is the accelerated structural change in the Radiopharmaceuticals segment. In 2007, what used to be straight trading with FDG increasingly began to resemble a manufacturing business with the construction of apparatus and its own cyclotrons in which the key work productivity parameters were lower than the commercial norm. As the segment displaying the strongest growth, it is also characterized by the fact that the block of fixed costs is "overpersonalized" and already geared toward the expected greater sales volume.

In the Nuclear Imaging and Industry segment, the Group's most important segment, constant exchange rate fluctuations meant that slight productivity increases of about one percent to EUR 204,000 per employee were recorded. The Therapy segment remained slightly below the level of the previous year

Development of the segments

with sales of EUR 179,000 per employee.

1. Nuclear Imaging and Industry

The Group's largest segment, the Nuclear Imaging and Industry segment, produces and sells radioactive components for industrial measurement systems, radiation sources for nuclear medicine imaging, calibration and measurement sources and also raw isotopes and other products.

In 2007, business with these articles was nominally slightly poorer than in the previous year and, with roughly constant sales with external customers (EUR 25 million compared with EUR 25.2 million in the previous year), the segment recorded a 13% lower result prior to minority shares of EUR 2.8 million (previous year: EUR 3.2 million). At first glance, business therefore appears to have been unsatisfactory in the year under review. As in previous years, the segment again sold more than 70% of its products in the United States and was therefore particularly susceptible to unfavorable effects resulting from exchange rate fluctuations. The fall in the value of the dollar against the euro impacted in full on sales and earnings in the segment and was in fact the real reason for the downturns mentioned above. In real terms and calculated using the previous year's exchange rate, the segment increased its earnings by approx. 7% and sales rose to EUR 26.9 million.

After the boost to sales recorded in 2006 and 2005 thanks to the purchase and full consolidation of Analytics Inc., the segment has thus returned in 2007 to the growth rates of previous years which as expected – lots of products are relatively mature – are singledigit percentages. Within this context, the real sales growth of 7% does in fact represent a very satisfactory figure which stands out from the series of figures seen in recent years. It is down primarily to the consistently high demand for components for industrial measurement applications. The Californian subsidiary Eckert & Ziegler Isotope Products Inc. occupies a strong position in this niche market which it was able to consolidate considerably in the year under review by securing several key American and Chinese customers.

In order to be able to continue to satisfy the demand from this sector in the future, the segment management team was able to complete several investment projects in the year under review enabling Eckert & Ziegler's position to be maintained or expanded in this sector. They included commissioning and obtaining official approval for a new production line at the Czech subsidiary Eckert & Ziegler Cesio s.r.o. and constructing a raw material store for longlife radioisotopes. One place where this is reflected is on the segment balance sheet on which inventories rose by EUR 0.9 million.

Sales of radiation sources for nuclear imaging, calibration sources and raw isotopes displayed a less dynamic trend in the year under review. Based on constant exchange rates, they maintained roughly their values of the previous year, but in nominal terms they fell slightly.

A positive impact was generated in 2007 by the market launch of the new IGG 100 gallium generator, which was developed in collaboration with the sister company Eckert & Ziegler EUROTOPE GmbH. It is aimed at nuclear medicine researchers and developers who are looking for a PET-compatible alternative to cyclotron isotopes for peptide labeling. In terms of its technical data, in particular its elution resistance and contamination with metal breaches, the IGG 100 is much better than other generators available in the market.

2. Therapy

The Therapy segment manufactures and sells implants for treating prostate cancer, ophthalmologic applicators for treating eye cancer, tumor radiation equipment, accessories for radiation therapy and other therapy products primarily for radio oncologists. The main sales markets are the European Union and neighboring regions (including Russia), which accounted for almost 90% of sales with external customers or EUR 18.3 million of the total sales of EUR 20.8 million. The remaining EUR 2.5 million of sales were essentially spread among deliveries carried over from the major order placed in 2006 from Venezuela and exports to Asia.

Compared with the previous year when EUR 19.8 million of sales were generated, the segment was able to increase its sales by 5%, which is to be regarded as an excellent achievement in view of the major order from Latin America in 2006. The product group displaying the strongest growth was "accessories for radiation therapy". The commercial goods, which Eckert & Ziegler does not manufacture itself but instead mainly distributes and sells in France for a brand-name manufacturer, benefited from a realignment of the product range and increased by more

Sales trends in individual segments (external sales)

n Nuklear Imaging and Industry n Therapy n Radiopharmacy (in million EUR)

Sales bysegments 2007

n Nuclear Imaging
and Industry 46%
n Therapy 38%

Sales trends byregions

n North America n Europe n Asia/Pacific n Others (in million EUR)

than a quarter. In 2007, the implants for treating prostate cancer also displayed double-digit percentage growth and achieved a sales volume of EUR 9.6 million (plus 22%). With the tumor radiation equipment, there was as expected a drop in sales on account of the high level of sales achieved in the previous year, but eye applicators maintained their 2006 level.

In terms of revenue, the Therapy segment's revenue prior to minority interests of EUR 0.7 million was just short of the segment's revenue result in the previous year (EUR 0.8 million), which was mainly attributable to the reassessment of the losses carried forward as part of the business tax reform and therefore to increased tax burdens without any effect on cash. By contrast, the profit before tax and minority interests improved by EUR 0.2 million to EUR 1.5 million. The essential reason for this was an improved interest result. This was down to what has now been the successful integration of the divisions acquired in recent years and the better control of current assets associated with this. The profit from operations itself (EUR 2.5 million) only slightly exceeded the previous year's figure (EUR 2.4 million) because of a disproportionate rise in distribution costs.

The segment recorded earnings before interest, taxes, depreciation and amortization (EBITDA) of EUR 4.3 million. This figure was EUR 0.4 million lower than the previous year's figure of EUR 4.7 million, in particular because at the end of 2006 a series of production lines which could have continued to be used perfectly well in industrial terms were completely written off and the volume of the write-offs in the year under review fell by EUR 0.5 million to EUR 1.8 million.

3. Radiopharmaceuticals

The Radiopharmaceuticals segment was newly created in 2006. It houses on the one hand the product group of synthesis modules for producing radiopharmaceuticals (Modular Lab) and on the other hand radiodiagnostics for diagnosing cancer. These shortlife preparations, which are also known as radioactive contrast media, are produced almost exclusively to order in special cyclotrons and "freshly" delivered every day. The most important products among the contrast media are the weakly radioactive sugar F-18 fluorodeoxyglucose (FDG) and radioactively labeled cholines.

In the year under review, developments in the Radiopharmaceuticals segment were characterized by significant growth in sales, the forecast continued fall in losses and, in terms of the balance sheet, the purchase of the Bonn-based company MC Pharma

GmbH. The following comments should be made about these developments:

Of the increase in sales with external customers of EUR 3.2 million to EUR 8.6 million, EUR 1.6 million of it (approx. half) was attributable to the new Modular Lab range of synthesis equipment, and a quarter of it was due to the successful outsourcing of the contrast media business from Berlin to Poland, in particular to Silesia (Gliwice and Wroclaw). The rest of the growth in sales resulted primarily from the sales generated by the new subsidiary Eckert & Ziegler EURO-PET Köln/Bonn GmbH (previously: MC Pharma). As in previous years, the main product was F-18 fluorodeoxyglucose (FDG), with roughly 20,000 patient doses being supplied in the year under review, primarily in Germany, Italy, and Poland.

The segment's loss, which was reduced by EUR 0.7 million, is mainly down to two factors. Firstly, in 2007 no special write-downs for development projects which were canceled were required, and secondly the sales, which were EUR 3.2 million higher, resulted in a gross profit margin which was EUR 1.7 million higher and as a result profit from operations which was EUR 0.6 million better than in the previous year. Although in terms of value (minus EUR 0.4 million) it is still negative, the loss is much better than the previous year's figure of EUR 1 million, especially if one considers that, following the successful market launch of Modular Lab in 2007, amortization on the development costs for this product range have been included in the profit from operations for the first time.

The positive effect of the improved profit from operations was neutralized by interest payments which increased by EUR 0.3 million and revenue from deferred taxes which fell by EUR 0.3 million. The increase in interest can be attributed to the acquisition of MC Pharma, and the disproportionate drop in tax revenues to a special effect in the previous year.

The profit from continuing operations remained at the 2006 level (minus EUR 0.9 million).

The purchase of MC Pharma, now trading as Eckert & Ziegler EURO-PET Köln/Bonn GmbH, which was substantially financed by a vendor loan, is reflected in a stretching of the balance sheet to the tune of roughly EUR 3 million. As the transaction affects the Group as a whole, it will be commented on in more detail in the following section on the Group's financial position and net assets.

Financial position and net assets

The changes to the balance sheet are slightly more pronounced in 2007 than in the previous period, but relatively low compared with fiscal years in which there were many acquisitions, for instance compared with the previous year. The balance sheet total rose slightly by EUR 3.4 million or 5% to EUR 67.6 million, with the equity ratio falling slightly by 3% to 54%. The fluctuations were not dramatic compared with recent years, including with the equity and total equity yield, which were each one percent lower than in the previous year and were 6% and 8%, respectively.

The changes on the balance sheet can essentially be attributed to a small number of factors. As well as the ever-present impact of currency effects which can be traced back to the fall in the rate of the US dollar against the euro, the balance sheet at the end of 2007 is dominated primarily by the purchase of MC Pharma, the shifting of a long-term loan which was due for repayment into current liabilities and the build-up of inventories. The following detailed statements can be made on these points:

  1. People familiar with the Group from previous annual reports will be well aware that the Group balance sheet is dependent on exchangerate fluctuations. This results from the fact that important Group subsidiaries, in particular the Californian subsidiary Eckert & Ziegler Isotope Products Inc., publish their balance sheets in the American currency. In addition, the Group invoices roughly a third of its sales on a dollar basis. Any appreciation or depreciation in currency therefore has a considerable impact on current assets, profits carried forward and debts.

  2. The acquisition of MC Pharma, now trading as Eckert & Ziegler EURO-PET Köln/Bonn GmbH, is reflected in a stretching of the balance sheet to the tune of roughly EUR 3 million. In terms of assets, it affects the property, plant and equipment and intangible assets which together rose by EUR 3.6 million to EUR 19.5 million; in the liabilities section of the balance sheet it affects the other current liabilities and the short-term loans which together grew by EUR 3.4 million to EUR 9.2 million. The background to the classification in the books as short-term is the obligation to repay the vendor loan for EUR 2.8 million by the end of 2008.

Balancesheet structure

Total assets 2007: TEUR 67,587

Total assets 2006: TEUR 64,173

Modular Lab for marking antibodies with radioactive isotopes

Cash flow

In contrast to the comparatively modest earnings figures which were influenced by considerable cashfree special effects, the Group's key liquidity figures displayed an excellent trend. Cash flow from operating activities in particular was robust, achieving a record level of EUR 6.6 million, the highest level seen in the last four years. It was EUR 2.0 million or 43% above the equivalent figure for the previous year.

Whereas in 2007 the inflow of liquidity from operating activities increased considerably compared with the previous year, the cash flows for investments and financing essentially corresponded to the values of previous periods, at least if they are adjusted to reflect the sales of securities. In the year under review, EUR 4.6 million was spent on investments in fixed assets, including the acquisition of consolidated companies. Although this was EUR 0.5 million or 13% above the 2006 level, this does not signal any change in the investment and acquisition strategy. As in the previous year, in 2007 loan commitments amounting to EUR 1.2 million net were repaid (2006: EUR 2.6 million), and a dividend of EUR 0.8 million was paid (previous year: EUR 0.5 million).

Despite these payments and the increase in operating output, the stock of liquid assets including securities only fell by EUR 0.4 million to EUR 5.4 million compared with the final day of the previous year. As the leverage ratio remained largely constant in the year under review, the Executive Board currently sees itself as being well equipped to finance further growth.

  1. The increase in the short-term borrowing obligations of EUR 1.6 million to EUR 4.1 million is a similar example of reclassification of liabilities which were previously non-current liabilities into current liabilities on account of due dates for repayment which are brought forward. Conversely, there is also a reduction in the liabilities to credit institutes of EUR 1.6 million to EUR 3.2 million. Here too, the background to this is provided by debt restructuring agreements due by fall at the latest for which offers have already been submitted to the Executive Board.

  2. Roughly half (EUR 0.9 million) of the increase in inventories of EUR 1.8 million to EUR 7.7 million, which is disproportionate compared with the growth in sales, is due to the strategic procurement of long-life radioisotopes in the Nuclear Imaging and Industry segment. These are used as raw materials for industrial radiation sources and, as a result of the technology involved, they are not always available in sufficient quantities at short notice. Customer orders already exist for the items held in stock. After the new production facility in Prague is commissioned, they will be processed continuously over the next few years.

Roughly EUR 0.5 million of the increases in inventories are attributable to the build-up of a stock of synthesis equipment and components in the "Modular Lab" product range which should enable short delivery times to be met. In terms of other major changes on the balance sheet amounting to more than one million euros, only the increase in provisions by EUR 1.1 million to EUR 5.1 million needs to be reported. Among other factors, this is due to increased bonus provisions and other provisions in the therapy sector.

Research & development

The research and development expenditure of the Eckert & Ziegler Group is only detailed to some extent as expenditure directly in the profit and loss account. As in line with IFRS the Group takes advantage of the option of activating development expenditure, most of the development activities appear as items on the balance sheet. Another factor leading to an underestimate of the expenditure on R&D is the fact that the Group only records development activities separately if development funds or investment allowances can be obtained in respect thereof.

The figure given for research and development expenditure in the profit and loss account therefore only provides a very rough indication of the Group's innovative strength. If it is applied as a measure for 2007, the EUR 0.3 million in the profit and loss account must be supplemented with another EUR 1.9 million of activated personal contributions which can be assigned to the development of Modular Lab. The total costs therefore amounted to roughly EUR 2.2 million, roughly EUR 0.4 million more than in the previous year.

Another indication of the innovative strength of the Eckert & Ziegler Group is the high level of sales achieved with new products in the year under review. The criterion used for "new" here is whether at the start of the year under review the article had been offered for sale by the Group for a maximum of two years, i.e. only from 2005 onwards. Based on this benchmark, it is apparent that all of the products in the Radiopharmaceuticals segment (contrast media and synthesis modules), and also those calibration and measurement sources that are produced by Eckert & Ziegler Analytics and the Czech company SORAD as well as all prostate cancer implants which are based on the new design intro-duced in August 2005, are counted as new products.

In the year under review, they accounted for sales of EUR 19 million. Compared with the total sales of EUR 55 million, this corresponds to a proportion of 34%. This is lower than in the previous year (42%), but this is not because there was less innovation taking place but instead is down to the fact that in the years prior to 2005 there were particularly intensive reorganization and restructuring efforts aimed at replacing the collapsed market in cardio-vascular radiation sources.

Specific details on the activities:

In the Radiopharmaceuticals segment, almost EUR 1.9 million was invested in the completion and improvement of the Modular Lab range of synthesis modules. Working together with academic partners, one of the achievements here was the development of automatic machines for labeling peptides with gallium-68. They utilize new manufacturing processes with improved process parameters and allow a whole range of gallium-DOTA peptides to be produced. The synthesis modules are thus suitable for a class of substances that is currently being researched in great depth by many users of nuclear medicine.

In order to be able to provide raw isotopes for the target group of gallium researchers and users, our Californian subsidiary Eckert & Ziegler Isotope Products Inc., working together closely with the Radiopharmaceuticals segment, introduced onto the market a gallium generator which is suitable for the synthesis modules in the year under review. The IGG 100 is noted for a previously unattained level of purity and a particularly stable level of productivity. With this generator, Eckert & Ziegler has secured a strong position in the global market for gallium products.

In the year under review, the developments achieved in the Radiopharmaceuticals segment also included the establishment and approval of a new process for producing 18F-fluoroethylcholine (FEC), a radiodiagnostic which can be used to confirm or rule out any suspicion of prostate cancer more quickly and more reliably than is possible using alternative methods. Citing a compassionate use clause in the Drug Registration and Administration Act, Eckert & Ziegler has also obtained authorization to market the product from the German Office for Drugs and Medical Products in Cologne, and has recently begun supplying FEC to a series of German hospitals.

Finally, in 2007 the team in the Radiopharmaceuticals segment successfully managed to establish a stable process for synthesizing a contrast medium which can be applied outside of traditional oncological indications. This medium is F-DOPA, a radiodiagnostic based on fluorine-18 which can be used to detect Parkinson's disease. In addition, in the year under review, work also began on a process for producing fluoroethyltyrosine (FET), which can be used to diagnose brain tumors.

The efforts of the developers in the Therapy segment were focused on expanding the range of accessories for the existing equipment ranges. Among other things, applicators were developed for treating cervical cancer and vaginal carcinomas which are used in brachytherapy with tumor radiation equipment of the Multisource® type. In addition to this, the engineers and technicians worked on new eye applicators based on iodine-125 which are suitable for treating malignant retinal and choroid tumors.

In the Nuclear Imaging and Industry segment, the development work was focused on the IGG 100 gallium-68 generator described above. In addition, the flexible flood source Perflexion® was patented, and a transportation and storage case for this calibration instrument was presented at the congress of the American Society of Nuclear Medicine. The new packaging unit was well received.

Eckert & Ziegler again received its main impetus for improving radioactive components from its traditionally close working relationship with manufacturers of imaging equipment (gamma cameras, PET scanners). Working in partnership with these original equipment manufacturers, nine new source designs specifically for PET and SPECT scanners were developed and marketed in the year under review. These were line sources and flood sources as well as 3D phantoms. Eckert & Ziegler boasts considerable resources for developing nuclear medicine imaging sources and is able to offer its customers specific solutions and customized designs.

The reference and calibration sources department stepped up its development activities for the plastic oscillator market and, with the PSC-0025 model, it marketed its fourth product which can be used to calibrate equipment for measuring body fluids and bacteria.

Opportunities and risks

Shareholders in Eckert & Ziegler AG must be aware that the company is exposed to a large number of opportunities and risks which may influence the company's business activities and share price. This report will now outline what risks and opportunities the individual segments display, and what effects this might have on the Group as a whole. Furthermore, the Group risk management and safeguarding measures that have been taken will be described.

Risk management

Eckert & Ziegler AG attempts to handle its business risks using a range of instruments. As part of the risk management system, yearly interviews with technical managers and leading executives are held at which new and existing risks are identified and ranked with respect to probability and potential effects on the company. As far as possible, preventive measures are taken to counter those risks which might damage the company, contingency plans are drawn up, and regular evaluations of these risk factors are organized. These include market and competitor surveys, evaluation of scientific literature, analysis of customer complaints, cost and sales statistics, and similar data.

Overall, a risk-minimizing approach is chosen. Existing risks are systematically monitored, and minimized or guarded against by means of ongoing process improvement. New product developments and acquisitions are tested for possible risks at the outset and incorporated into the risk management system. Market developments are monitored, as are the activities of competitors, so that our own strategies can be modified and implemented at an early stage.

Group accounting at Eckert & Ziegler AG is responsible for observing and evaluating prevailing risks on a regular basis and reports to the Executive Board. These reports form the basis for regular meetings of the Executive Board at which significant risks to the survival and earnings of the Group and its subsidiaries are presented and discussed.

The Supervisory Board, to which all the main decisions are presented, explained and submitted for approval, and which is kept regularly informed about economic developments, serves as a further safeguard against risk.

Financial risks

At this point, the Group considers itself in possession of sufficient financial means to secure its position as well as to further development. It also sees itself as capable of meeting all financial obligations. However, in the coming business years, it anticipates a slight increase in the debit ratio in order to secure growth via further acquisitions and to finance the development of new products.

In addition to economic and technical development risks, Eckert & Ziegler is also subject to the vicissitudes of the market. These can lead not only to revenue risks as a matter of course but also to liquidity risks, since the Group has received outside financing for some of its acquisitions and has provided guarantees for loans to its subsidiaries. The Group remains susceptible to problems even if the management reacts rapidly to reduce costs and/or leave a threatened field of activity. However, the Executive Board is taking measures to limit risks through loans and guarantees in an amount which is justifiable in relation to the Group's overall assets.

Monitoring and control measures to avoid financial risk include the use of such instruments as the annual financial budget with revisions during the year, and fine-toothed analysis of deviations from the budget. This enables potential risks to be identified at an early stage and suitable countermeasures to be implemented. Due to the high proportion of sales in the US, there is a certain degree of dependence on the US dollar exchange rate. However, because the subsidiary in the US responsible for most of this revenue also incurs its costs in US dollars, the effects of changes in the exchange rate are less than for conventional export business. For German exports, sales in foreign currencies are hedged by forward exchange contracts and simple put options when required.

At the time of reporting, the companies Eckert & Ziegler Strahlen- und Medizintechnik AG, Eckert & Ziegler Bebig GmbH and Eckert & Ziegler Eurotope GmbH are undergoing an audit. The results of this audit are uncertain especially as different effects, some of which compensate one another, confront one another and the individual facts and circumstances have not yet been definitively clarified. It is possible that, given a one-sided interpretation by the financial auditors, a payment of tax arrears may have to be made or a legal dispute may ensue.

Legal risks

The acquisitions of recent years have given rise to some contractual risks for the Group. Although the Executive Board sought to contain all risks in advance by means of unmistakable provisions and the services of qualified attorneys, disputes can still arise over the interpretation of contracts. The Group is currently facing an additional purchase price demand, with an attempt at court to have more than EUR 1 million in back payments made from the acquisition of MCP Medical International GmbH (now: Eckert & Ziegler MMI GmbH) in March 2004. The Board views this suit as groundless but cannot exclude the possibility that this or similar actions find backing. Yet it would be inadvisable to refrain from acquisitions in order to avoid all risk. In the past, the Group has been able to add a number of profitable business fields only via acquisitions, and we must continue to accept such risks in the future in the interest of further development.

Personnel risks

In many segments, Eckert & Ziegler depends on the specialized knowledge of its employees. Especially in setting up new business fields, but also in development and sales, it relies on the expertise and skills of a few particularly well-qualified key individuals. In order to minimize the risk of losing talented personnel, the company strives to create a friendly and supportive atmosphere, a modern and secure working environment, adequate compensation, professional training and further education opportunities, and flexible working hours. The company has also launched a share option program to enhance longterm loyalty and motivation. Despite these measures and a demonstrated high degree of employee satisfaction, Eckert & Ziegler cannot guarantee that these employees will remain with the company or display the necessary commitment.

General risks associated with production and handling radioactivity in particular and opportunities arising from this

The production risk includes the risk of being unable to buy all the raw materials and consumables at the right time and in the necessary quantities. This risk can be reduced by warehousing and by establishing alternative procurement sources, but it can never be eliminated altogether. With products being dispatched all over the world, in many cases as hazardous materials, Eckert & Ziegler is dependent on

specialized service providers. There can be no guarantee that these services will be sustained in their existing form. Official licenses and permits are needed for the production and dispatch of many products, and Eckert & Ziegler AG can only exert indirect influence on when these are issued or renewed.

Both radioactivity itself and its use in medical or pharmaceutical products entail product liability risks. Eckert & Ziegler is addressing these risks by adhering to strict quality criteria. Its operational facilities are ISO-certified, and its quality management systems are regularly checked by both internal and external audits. In order to avoid accidents that injure employees, cause damage to the environment, or prompt regulatory agencies to close down production facilities, staff members regularly undergo training in occupational safety and radiation protection. Despite all these measures, it cannot be excluded that events giving rise to liability could occur and pose a threat to the company. As far as possible and feasible, appropriate insurance has been taken out to guard against liability risks.

Eckert & Ziegler has undoubtedly acquired a great deal of know-how thanks to its many years of experience in handling radioactivity. This experience also provides a safeguard against new competitors entering the market as well as a wide range of options for accelerating organic and acquisition-driven growth in these business fields.

General strategic risks

As a specialist for a broad portfolio of radioactive components, radiation equipment and radiopharmaceutical products, Eckert & Ziegler is better protected against slumps in the market than single-product companies. Although the different business fields feature related technology, they differ considerably in their product life cycles and in their customer and market structures. This variation generally lowers the risk that competitors will undermine the company's business foundation with new and better products. Nevertheless, the possibility cannot be entirely excluded that improved processes and efforts on the part of the competition might lead to the loss of important markets, and thus endanger the company.

To counter this threat, Eckert & Ziegler is actively seeking to develop new products and to identify and set up new business fields. However, the risk exists that these efforts will remain unsuccessful and that new business fields can only be developed too late, or inadequately, or not at all. Furthermore, the possibility cannot be ruled out that competitors will undertake more successful actions with other products or marketing strategies.

Risks in the Nuclear Imaging and Industry segment

Many nuclear medicine and industrial subsegments have oligopolistic market structures, which means that the loss of major customers can have a marked impact on revenue and sales. Eckert & Ziegler AG strives to counter these sales risks by setting up medium and long-term supply contracts, but it cannot guarantee that it will always be successful at this endeavor in the future.

The segment relies on possibilities for disposing of radioactive waste produced when taking back sources from customers and during production. There are signs that one of these disposal facilities in the USA is set for closure, as a result of which Eckert & Ziegler anticipates higher costs at the remaining facilities. Efforts are being made to counter the increases in costs by adopting internal recycling which reduces external waste.

Strategic risks and market risks in the Therapy segment

Major sales and revenue risks continue to lie in developing the European market for permanent implants for the treatment of prostate cancer. This innovative treatment method in European countries still faces the problem that the reimbursement by statutory health insurance programs is essential for the economic success of this method – in some key countries it is either not yet or only partially secured. In addition, the competitive situation has also reduced the profit margin here. Eckert & Ziegler is attempting to enhance customer loyalty via an attractive service program and long-term supply contracts, and thus counter existing risks to sales and earnings.

Sales of radiation systems are still subject to the risk that market penetration in the primary target markets will not take hold as expected or will be delayed due to high capital expenditures and follow-up costs. However, the year under review has shown that the equipment further developed permanently from the created sales structures could be well placed in the market.

Risks in the Radiopharmaceuticals segment

In the new Radiopharmaceuticals segment, a risk to sales exists in the possibility that the necessary

authorizations might not be granted or might be withdrawn. It is also possible that both the number of new customers and the sales themselves might not develop as expected due to less than ideal decisions on cost reimbursement by statutory health insurance programs.

Even as part of the process of examining the acquisition of Eckert & Ziegler EURO-PET Köln/Bonn GmbH (previously: MC Pharma GmbH), it was apparent that the cyclotron installed there was of an older design and the manufacturer Siemens would soon stop producing spare parts and providing customer service for the facility. A model calculation was therefore used to run through the worst-case scenario, which involved having to replace the cyclotron. However, even this scenario proved to be profitable. A replacement now even appears less likely because spare parts have since been procured and a number of employees have received training in maintenance and service.

Changes to risks

In spite of the growth in its range of products, there has been no heightening of the risk profile for the Eckert & Ziegler Group which could endanger the company's intrinsic value. A large number of prevailing risks have already been considered in the Group's detailed planning for the coming year. The Executive Board does not expect that there will be significant impact on fiscal year 2008 stemming from the abovementioned risks.

Post balance sheet events

In February 2008, Eckert und Ziegler AG invested its stake in Eckert & Ziegler BEBIG GmbH as a contribution in kind in International Brachytherapy S.A. (IBt), Seneffe (Belgium) and in return for this it received 38.5% of the nominal shares (or 29.9% of the voting shares) in IBt arising from a capital increase. In this connection, Eckert & Ziegler AG invested its claims against Eckert & Ziegler BEBIG GmbH as a capital reserve in Eckert & Ziegler BEBIG GmbH.

Outlook

In fiscal year 2008, the Group anticipates a considerable growth in sales, especially because in this period Eckert & Ziegler EURO-PET Köln/Bonn GmbH (formerly MC Pharma), which was purchased in October 2006, will be recorded with its full-year sales revenues for the first time. Another factor is that in February 2008, as part of a merger of the prostate cancer implant divisions, the Group not only emerged to become the biggest shareholder in International Brachytherapy (IBt). As part of this transaction, Eckert & Ziegler also acquired an option to purchase a further share package and, if it were to exercise this

option, it could hold more than 50% of all the shares in its former competitor. However, in accordance with the regulations of International Financial Reporting just the theoretical possibility of being able to acquire and therefore control the majority of the votes at an annual general meeting results in a duty to consolidate, which is why additional sales of roughly EUR 10 million arising from the inclusion of IBt in the Group companies which are consolidated are expected for fiscal year 2008. Together with the Group's organic growth and the boost to sales from the initial consolidation of Eckert & Ziegler EURO-PET Köln/Bonn GmbH, the sales threshold of EUR 70 million will probably be broken – provided that the dollar enjoys a stable exchange rate against the euro.

On the earnings side, the purchase of the package of shares and the consolidation of IBt are resulting in a cascade (currently difficult to overlook) of effects which boost profits on the one hand and reduce profits on the other.

However, a factor that will reduce profits in the medium term is the fact that, as part of the transaction, Eckert & Ziegler sold its profitable implants division to IBt. The Group therefore no longer enjoys the benefit of all the profits from the division but instead

just 40% of the revenue from the joint venture company. In the initial phase at least, this share will be lower than any anticipated profit from the implant division that has been sold off. However, for strategic reasons, Eckert & Ziegler has accepted the dilution of its entitlement to a share in profits in favor of IBt's existing shareholders. The Executive Board is confident that the combination of the two companies will generate greater growth and therefore higher revenues over the longer term than would be possible by going it alone.

The crucial factor in determining whether profits can be maintained over the long term will therefore be the rate at which the earnings for the merged implant businesses grow, and whether the growth is sufficient for Eckert & Ziegler in fiscal year 2008 to compensate for the value of the profits relinquished in 2008.

Remuneration report

Executive Board remuneration

Executive Board remuneration is set by the Supervisory Board and is subject to reevaluation by the Supervisory Board roughly every two to three years. The Executive Board remuneration is currently composed of fixed and variable payment components. When determining the amount of the overall remuneration as well as the distribution of the individual remuneration components, the Supervisory Board bases its decisions on appropriateness. The conferred area of responsibility, personal performance, and the experience of the Executive Board member, the company's outlook for the future, and the competition situation are key factors here.

Fixed remuneration represents about half the total remuneration of the Executive Board members. It is in the form of a fixed salary and non-monetary items. The fixed salary includes allowances for health, longterm care and retirement insurances in addition to the basic remuneration. Non-monetary compensation consists primarily of providing company cars.

Variable remuneration components are also designated. These are non-recurring and annually recurring remunerations linked to short-term business success. One-off bonuses may be granted in recognition of outstanding performance. An agreement providing for an annually recurring profit-sharing bonus is based on the consolidated profit and loss statement as per IFRS and is limited in the amount paid.

Variable remuneration components which are attractive over the long term and are risky in nature are no longer provided following the expiry of the company's former share option program. However, members of the Executive Board still hold share options from this program which they were granted in previous fiscal years and they have not yet exercised. The share option program entitles the share option owner to exercise his/her rights on a defined number of shares. The earliest the options may be exercised is after a vesting period of two years from the date of issue and they can be exercised only within specified dates. Further, it is possible to exercise these rights only if the share price increase in the period between date of issue and the first period for exercising option rights exceeds the Technology All Share Index in the same period.

In the event that an Executive Board member's employment is terminated, there are no promises of severance payment. Share options can be exercised only as long as there is a contractual relationship with the company or with one with which it is associated. There are no agreements with Executive Board members concerning company retirement arrangements.

Of the total remunerations for fiscal year 2007 totaling EUR 966 thousand, EUR 586 thousand were fixed and EUR 380 thousand were short-term performancerelated remuneration components (see table 1 below).

There were no payments to former Executive Board members or their heirs in fiscal year 2007. There are retirement benefit provisions for a former Executive Board member totaling EUR 98 thousand.

Supervisory Board remuneration

In compliance with statutory provisions, Supervisory Board remuneration consists of an annual fixed compensation of EUR 6,000, whereby the chairperson receives double that amount and a deputy chairperson one and a half times that amount. The members of the Supervisory Board receive no profit-related remuneration.

In addition to the fixed annual remuneration, members of the Supervisory Board receive EUR 750 for every punctually and fully attended Supervisory Board meeting.

The sales tax is reimbursed by the company provided that the members of the Supervisory Board are entitled to submit a separate sales tax invoice to the company and do so.

For services rendered beyond the scope of Supervisory Board responsibilities, in particular for advisory and brokering services, no remunerations were granted in the reporting year.

In fiscal year 2007, the Supervisory Board members received fixed remunerations of EUR 45 thousand and emoluments for meetings totaling EUR 21 thousand. Total expenditures were thus EUR 66 thousand (see table 2 below).

Directors' dealings

Directors' dealings pursuant to paragraph 15a of the Securities Act (WpHG) were not reported to the company in 2007.

Directly or indirectly, members of the Executive Board own more than 1% of the shares is-sued by the company, namely 38.24%. Members of the Supervisory Board own less than 1% of the shares issued by the company.

Table 1 Fixed remuneration components Shortterm performance-
related remuneration components
Total
Fixed salary Non-monetary compensation Profit sharing/Bonus
TEUR TEUR TEUR TEUR
Dr. Andreas Eckert 256 7 200 463
Dr. Edgar Löffler 180 10 150*) 340
Dr. Andreas Hey 133 0 30 163
Table 2 Remunerated position Fixed remuneration Meeting allowances
TEUR TEUR Total
TEUR
Prof. Dr. Wolfgang Maennig Supervisory Board Chairperson 12 3 15
Ralf Hennig Supervisory Board Deputy Chairperson 9 4 13
Prof. Dr. Ronald Frohne Supervisory Board member 6 2 8
Prof. Dr. Nikolaus Fuchs Supervisory Board member 6 4 10
Frank Perschmann Supervisory Board member 6 4 10

*) Payment of a partial sum of EUR 100,000 into a support fund which serves the purpose of providingcongruent back-up for a promised provision.

All around the world, the personal dedication of our employees ensures that customers, investors and other business partners choose Eckert & Ziegler. Developing and expanding their skills on an individual basis is therefore an essential investment in the company's future. Specific support and education is also of key strategic importance for the company because know-how, motivation, application and creativity among employees represent a crucial competitive advantage and will shape our expertise for the future.

Staff

Staff byareas 2007

n F&E 14%
n Production 40%
n QM 9%
n Sales and marketing 26%
n Administration 11%

In the year under review, the average number of people employed by the Group per month rose by 36 to 327. The main reason for this rise was the acquisition of Eckert & Ziegler EURO-PET Köln/Bonn GmbH.

In the period under review, staff costs amounted to EUR 14.5 million (2006: EUR 13.5 million). Roughly half of all employees hold a diploma from a university of applied science or a higher qualification. The Group invested TEUR 124 (2006: TEUR 116) in advanced training for employees.

In order to make it easier to combine family and professional life, Eckert & Ziegler offers, among other things, flexible daily and weekly working hours, parttime work and healthcare, and maintains employee contact with the company during periods of parental leave through a regular exchange of information, as well as running programs to assist people's return to work. The Group also promotes individual advanced training and education for employees with internal English courses and post-graduate studies in the areas of business management and medical physics.

In the 2007 fiscal year, numerous interns, students and graduates again took advantage of the opportunity afforded by their studies to familiarize themselves with Eckert & Ziegler AG as an interesting employer. A number of them were offered a permanent position after completion of their projects.

Eckert & Ziegler is a training company and believes that taking on trainees both helps it to retain its own employees and provides school leavers with professional prospects in an industry with a promising future. In 2007, the Group was able to provide permanent employment for all trainees who completed their training.

In an attempt to find a better balance between the interests of employees and the interests of the company, Eckert & Ziegler has created a monthly bonus system for many divisions within the company. In 2007, 88 employees, equating to roughly 27% of the workforce, participated in this. Furthermore, the proportion of employees who have a variable element to their pay but are not part of the management team was increased continuously.

In the year under review, the average time lost through sickness and illness in the Group was 1.91% and this was considerably lower than the state average and the average at a national level (Berlin-Brandenburg 3.7%, nationally 3.29%).

The Executive Board would like to take this opportunity to thank all members of staff for the commitment they have displayed and the efforts they have made. Thanks are also due to the works council, which, by liaising between the company's management and its workforce, has played its part in enabling many decisions to be implemented.

20th EANM AnnualCongress in Copenhagen

Annual General Meeting in Berlin

Tenth company anniversary

Marketing and Public Relations

In the 2007 fiscal year, marketing activities were again focused on boosting the profile of Eckert & Ziegler and promoting sales. The main tools used for this were once again the Internet, printed material as well as stands at congresses and trade fairs. The operating subsidiaries of Eckert & Ziegler AG were represented at 47 events in Germany and abroad.

The structure of the document database (SalesNET), which was introduced two years ago, has been continuously expanded and updated. Via the Internet it allows global access to relevant product information. A special facility is offered by a newly introduced notification service which enables users to easily find out information about product changes and innovations. From now on, important marketing documents will also be available in French, Polish and Spanish.

A public relations highlight was the company's tenth anniversary which Eckert & Ziegler AG celebrated in the summer of 2007 together with guests from the worlds of politics, business and culture at a Berlin club.

The Group continues to be committed to socio-political causes. The "Forschergarten" initiative, which was launched by Eckert & Ziegler and the "Gläsernes Labor" in Berlin-Buch and is intended to improve young children's natural science education, was honored as a "Ausgewählter Ort im Land der Ideen 2007" (2007 Selected Site in the Land of Ideas).

In November, together with the umbrella organization for the nuclear medicine federations in Europe, the EANM (European Association of Nuclear Medicine), a prize was awarded to young, talented practitioners of nuclear medicine. The "EANM Eckert & Ziegler Abstract Award" is intended to help to promote up-and-coming talent and features a travel grant.

34 Eckert & Ziegler . Annual Report 2007

Environment and Safety

In 2007, the emission of pollutants into the environment as a result of Group production activities was once again low. Radioactive materials are only processed within closed circuits, and the quantities are low. In addition, production is carried out under negative pressure, and the exhausted air is centrally filtered.

In order to improve safety in the workplace, efforts are therefore being focused primarily on avoiding and reducing exposure to radiation. In the year under review, despite increasing production volumes in all segments, optimization of processes and systems meant that staff exposure to radiation was kept at the very low level of previous years. In the therapy segment, the average value for 2007, the year under review, is in fact less than 1% of the legally stipulated value.

In 2007, high priority was given to the implementation of the law on the distribution, taking back and environmentally friendly disposal of electrical and electronic equipment. This includes demonstrating that none of the substances which are banned under the law are used to produce the equipment, guaranteeing that the equipment will be taken back and ensuring that the used devices will be recycled in accordance with the regulations.

A key element of health and safety in the workplace is an extensive range of instruction and training which is on offer: All employees receive instruction at least once a year about all of the potential risks and hazards in the area in which they work and they are familiarized with the necessary code of conduct. All working areas with an increased risk potential are supervised by employees who have the appropriate level of expertise to manage this risk potential. For example, at the Berlin plant a total of 29 employees are experts on radiation protection and are appointed as radiation pro-tection officers with the supervisory authority.

At the Berlin plant, there were a total of 23 further training courses (compared with 37 the previous year) in the year under review, 12 of these relating to safety in the work-place (compared with 12 the previous year) and 11 relating to radiation protection. The reduced number of radiation protection courses can be attributed to the fact that in the previous year more people were affected by the sequential update than in the year under review.

The level of safety in the workplace is demonstrated by the fact that, for seven years now, there have been no accidents at work whose causes could be attributed to the lack of protective equipment or technical defects. Apart from road accidents and trivial incidents, not a single workplace accident had to be documented and forwarded to the relevant authority in the period under review. As far as radiation protection is con-cerned, there were also no incidents which had to be reported.

The production facilities, supply units and other equipment are inspected at regular intervals for any defects which may have an impact on safety and new production facilities are approved and signed off by independent experts. This ensures that even the most minor defects or signs of wear can be identified in good time and the safety of plants can be maintained at the highest level. Before a newly created workplace is approved, the hazard which it poses is always evaluated first of all and this is then reevaluated at least every three years for existing workplaces as well.

Quality Management

As a manufacturer of medical products and radiopharmaceuticals, Eckert & Ziegler is legally obliged to maintain comprehensive, formalized quality assurance systems. Responsibility for this is borne primarily by the manufacturing subsidiary companies which are regularly inspected by external authorities, for instance TÜV or the German Calibration Service, to ensure compliance with the guidelines. In addition, for its own benefit, the company constantly seeks to improve on and exceed the required standards. In order to support this aim, it has concluded bonus agreements with a large number of managers and employees relating explicitly to quality targets.

The most important inspection audit in the year under review was conducted in June 2007 by TÜV Nord CERT GmbH for the leading business in the therapy sector, Eckert & Ziegler BEBIG GmbH. The audit confirmed that the quality assurance systems conform to the European and Canadian directives and standards. Specifically, the following certificates were authenticated as part of this.

  1. Certificate in accordance with Annex II of EC Directive 93/42/EEC. Area of validity: "Brachytherapy radiation sources, brachytherapy afterloading systems"

  2. Certificate in accordance with Annex 2 of EC Directive 90/385/EEC. Area of validity: Implantable seeds and accessories for brachytherapy

  3. Certificate for the management system in accordance with DIN EN ISO 9001:2000. Area of validity: "Development, manufacture and distribution of radioactive components for medical applications"

  4. Certificate in accordance with EN ISO 13485:2003. Area of validity: Development, manufacture and distribution of brachytherapy radiation sources, brachytherapy afterloading systems and blood irradiation equipment

  5. Certificate in accordance with Canadian standard CAN/CSA ISO 13485:2003 (Medical Devices Regulation). Area of validity: Development, manufacture and distribution of radioactive sources and equipment and accessories for brachytherapy

The certifications also apply to the products of STS Steuerungstechnik + Strahlenschutz GmbH, which is integrated into BEBIG's quality management system, and to Eckert & Ziegler Isotope Products GmbH (IPE), to the extent that BEBIG processes also apply to them.

In the year under review, an independent expert also confirmed that the Modular Lab synthesis equipment range meets the requirements which are placed on equipment used to manufacture pharmaceuticals at both a national and international level. Among other things, Modular Lab hereby satisfies the requirements of Good Automatic Production (GAMP4, 21 CFR Part 11).

Since a quality management system was first implemented in 1998, the Eckert & Ziegler Group has in each case received – with no notable objections – all certifications currently in force.

Quality control on contrast media using HPLC analysis

Consolidated Statements of Income 40
Consolidated Statements of Cash Flows 41
Consolidated Balance Sheets 42
Consolidated Statements of Shareholders' Equity 43
Notesto the Group Financial Statements 44
Other disclosuresrequired under HGB 74

Consolidated Financial Statements of the Eckert & Ziegler Group

Consolidated Statements of Income

Years ended December 31

2007 2006
(Amounts in thousand EUR except for per share data) Note TEUR TEUR
Revenue 6. 54,444 50,378
Cost of sales 7. -27,579 -26,464
Gross
profit
on
sales
26,865 23,914
Selling expenses 8. -10,231 -8,652
General and administrative expenses 9. -10,453 -10,307
Research and development expenses 10. -289 -333
Other income 13. 564 1,451
Other expense 14. -485 -196
Profit
fromoperations
5,971 5,877
Result from shares evaluated at equity 15. 9 -9
Other financial items 16. -292 -324
Earnings
beforeinterestand
tax(EBIT)
5,688 5,544
Interest yield 63 74
Interest paid -830 -870
Profit
beforetax
4,921 4,748
Income tax expense 18. -2,771 -1,611
Profit
fromcontinuing
operations
2,150 3,137
Profit from discontinued operations, net (including income from the
discontinuation and deconsolidation of Altmann GmbH & Co. KG
of EUR 398 thousand)
21. 0 -592
Profit
for
theyear
2,150 2,545
Of which: share of profit attributable to minority interest 19. 202 324
Of which: dividend to shareholders of Eckert & Ziegler AG 1,948 2,221
Earnings
per
share
20.
Basic 0.62 0.71
Diluted 0.61 0.70
Earnings
per
share

continuing
operations
Basic 0.62 0.90
Diluted 0.61 0.89
Earnings
per
share

discontinued
operations
Basic 0.00 -0.19
Diluted 0.00 -0.19
Average number of shares in circulation (basic)
in thousands
3,142 3,131
Average number of shares in circulation (diluted)
in thousands
3,171 3,167

Consolidated Statements of Cash Flows

Years ended December 31

2007 2006
Note TEUR TEUR
Cash
flows
fromoperating
activities:
39.
Profit for the year 2,150 2,545
Adjustments for:
Depreciation and amortization
(of which: EUR 64 thousand included as profit from discontinued operations) 3,731 4,601
Interest paid 767 796
Interest payments - 573 - 749
Tax on earnings 2,771 1,611
Tax on earnings paid - 1,854 - 2,405
Proceeds from grants less release of deferred
income from grants 37 - 551
Deferred tax - 10 113
Expense from share optionplan 104 117
Unrealized foreign currency gains/losses 265 341
Effect of foreign currency rate changes on operating cash flows 15 16
Long-term provisions, other non-current liabilities 517 128
Book gains on deconsolidation of Altmann - - 398
Losses on the disposal of non-current assets 18 71
Gains (-)/losses on the sale of securities 1 - 55
Other items - 128 - 7
Changes in current assets and liabilities:
Receivables 87 - 1,871
Inventories - 2,051 - 125
Prepaid expenses and other current assets - 8 - 60
Trade accounts payable and accounts
payable to related parties 146 318
Profit tax liabilities 31 - 457
Other Provisions 1,183 1,068
Deferred income - 11 2
Other liabilities - 557 - 488
Cash
inflows
generated
fromoperating
activities
6,631 4,561
Cash
flows
frominvesting
activities:
40.
Additions to non-current assets - 4,685 - 4,162
Sale of non-current assets 212 127
Acquisition of consolidated enterprises* - 188 - 25
Sale of shareholdings 15 -
Sale of securities 70 1,387
Cash
outflows
frominvesting
activities
- 4,576 - 2,673
Cash
flows
fromfinancing
activities:
41.
Dividends paid - 786 - 469
Distribution to minority interests - 272 - 251
Purchase/sale of own shares 21 22
Receipts from the take-up of long-term borrowings 294 -
Repayments of long-term borrowings - 1,203 - 2,575
Change in short-term borrowings - 250 1,325
Cash
outflows
(cash
inflows
in
previousyear)
fromfinancing
activities
- 2,196 - 1,948
Effect of exchange rates on cash and cash equivalents - 167 - 207
Net
decreasein
cash
and
cash
equivalents
- 308 - 267
Cash
and
cash
equivalentsat
beginning
of
period
4,683 4,950
Cash
and
cash
equivalentsatend
of
period
4,375 4,683

* Another part of the purchase price of MC Pharma GmbH involved the takeover of an additional loan liability amounting to EUR 181,000 with respect to the vendor. (See also explanations given under Point 42.)

Consolidated Balance Sheets

As of December 31, 2007 and 2006

2007 2006
Note TEUR TEUR
Assets
Non-currentassets,
total
Intangible assets 22. 18,234 17,985
Property, plant and equipment 23. 17,745 15,920
Equity investments 68 68
Financial investments reported according to the equity method 42. 0 6
Other loans 24. 44 48
Deferred tax assets 18. 3,081 4,118
Other assets 25. 1,630 2,036
Total
non-currentassets
40,802 40,181
Currentassets
Cash and cash equivalents 26. 4,375 4,683
Securities 27. 1,033 1,081
Trade accounts receivable 28. 11,459 11,110
Receivables from related people and companies 5 27
Inventories 29. 7,713 5,888
Other assets 30. 2,200 1,204
Total
currentassets
26,785 23,993
Totalassets 67,587 64,174
Equityand
liabilities
Shareholders'equity 31.
Subscribed capital 3,250 3,250
Capital reserve 29,750 29,632
Retained earnings 7,230 6,068
Other reserves -3,734 -2,679
Own shares -359 -366
Equity to which the shareholders in Eckert & Ziegler AG are entitled 36,137 35,905
Minority interest 354 424
Total
shareholders'equity
36,491 36,329
Non-current
liabilities
Long-term borrowings and finance lease obligations 32. 3,921 7,319
Deferred income from grants and other deferred income 33. 1,369 1,270
Deferred tax liabilities 18. 1,339 1,706
Rückstellungen für Pensionen 34. 98 129
Other non-current liabilities
Total
non-current
liabilities
35. 3,653
10,380
3,449
13,873
Current
liabilities
Short-term borrowings and and finance lease obligations 32. 8,256 3,365
Trade accounts payable 3,885 3,855
Advance payments received 290 331
Provisions 36. 5,139 3,971
Deferred income from grants and other deferred income
Current tax payable
33.
18.
935
578
960
300
Other current liabilities 37. 1,633 1,190
Total
current
liabilities
20,716 13,972
Totalequityand
liabilities
67,587 64,174

Consolidated Statements of Shareholders' Equity

As of December 31, 2007 and 2006

Subscribed capital Cumulative other equity items
Unrealized
Equity attrib- Group
share
Shares Nominal
value
Capital
reserve
Retained
earnings
gains/losses on
securities
Exchange
differences
Own
shares
utable to
shareholders
Minority holders
interest
equity
TEUR TEUR TEUR TEUR TEUR TEUR TEUR TEUR TEUR
Balance January 1, 2006
Dividends paid
Cost of share option plan
Application of own shares for
3,250,000 3,250 29,346
116
4,316
-469
41 -1,664 -434 34,855
-469
116
100 34,955
-469
116
acquisitions and to service
share option plan
Profit for the year
170 2,221 68 238
2,221
324 238
2,545
Unrealized gains/losses on
securities at balance sheet date
(after tax of EUR 14 thousand)
Reversal of unrealized
22 22 22
gains/losses on securities at
previous balance sheet date
-41 -41 -41
Total income for the period
Foreign currency translation
differences
0 0 286 2,221 -19 0
-1,037
68 2,556
-1,037
324 2,880
-1,037
Balance December 31, 2006 3,250,000 3,250 29,632 6,068 22 -2,701 -366 35,905 424 36,329
Shares value reserve earnings securities differences shares shareholders interest equity
TEUR TEUR TEUR TEUR TEUR TEUR TEUR TEUR TEUR
Balance January 1, 2007 3,250,000 3,250 29,632 6,068 22 -2,701 -366 35,905 424 36,329
Dividends paid -786 -786 -272 -1,058
Cost of share option plan 104 104 104
Application of own shares for
acquisitions and to service
share option plan 12 9 21 21
Acquisition of own shares 2 -2 0 0
Profit for the year 1,948 1,948 202 2,150
Unrealized gains/losses on
securities at balance sheet date
(after tax of EUR 18 thousand) 42 42 42
Reversal of unrealized
gains/losses on securities at
previous balance sheet date -22 -22 -22
Total income for the period 0 0 118 1,948 20 0 7 2,093 202 2,295
Foreign currency translation
differences
-1,075 -1,075 -1,075
Balance December 31, 2007 3,250,000 3,250 29,750 7,230 42 -3,776 -359 36,137 354 36,491

As of December 31, 2007 and 2006

Background, principles and practices

1. Organization and description of business activities

Eckert & Ziegler Strahlen- und Medizintechnik AG, Berlin (hereinafter referred to as "Eckert & Ziegler AG" or "the Company") is a holding company whose specialized subsidiaries are engaged worldwide in the processing of radioisotopes and the development, manufacture and sale of components based on isotope technology, radiation equipment and radiopharmaceuticals or of related products. The main areas of application for Group products are in medical technology, particularly in cancer therapy, as well as in nuclear-medical imaging and industrial radiometry. In these areas, the products of Eckert & Ziegler AG and its subsidiaries are aimed at radiation therapists, radio-oncologists and nuclear-medical specialists, among others.

The Company operates in a market characterized by rapid technological progress, heavy research expenditure, and constant new scientific discoveries. This market is subject to supervision by German Federal, State and local authorities. These regulatory authorities include the Regional Office for Health and Social Affairs Berlin (LAGeSo), the Technical Monitoring Agency (TÜV Nord CERT GmbH, Essen), the Federal Drug Office (BfArM) along with the corresponding foreign institutions, such as the US Food and Drug Administration (FDA) or the Nuclear Regulatory Commission (NRC). The Company is, therefore, directly affected by changes in technology and in products used in cancer treatment and for nuclear-medical imaging, by government regulations related to the industry in which Eckert & Ziegler AG operates, and by the general business environment within healthcare.

2. Reporting principles

The consolidated financial statements of Eckert & Ziegler AG as of December 31, 2007 have been prepared in accordance with International Financial Reporting Standards (IFRS). All the standards of the International Accounting Standards Board (IASB), London, applicable in the EU at the balance sheet date, as well as the relevant interpretations of the International Financial Reporting Interpretations Committee (IFRIC) and the Standing Interpretations Committee (SIC) have been followed. In addition, the supplementary applicable commercial provisions of Section 315a para. 1 HGB (German Commercial Code) have been observed. The Group financial statements, therefore,

convey a fair presentation of the net assets, financial position and result of operations of the Group. The reporting currency is the Euro. The amounts shown in the Group financial statements have been rounded to thousand Euros.

The financial statements of subsidiaries have been prepared as of the same date as the consolidated financial statements, this balance sheet date corresponding to that of Eckert & Ziegler AG. The annual financial statements cover the period under review from January 1 to December 31, 2007. The income statement has been prepared in accordance with the cost of sales method of presentation.

The Company is registered with the Commercial Register at Berlin-Charlottenburg under the number HRB 64 997 B and the consolidated financial statements and the Group management report as of December 31, 2007 were published in the electronic version of the Federal Official Gazette.

3. Accounting and valuation principles

Accounting and valuation policies – The reporting of assets and liabilities of the German and foreign subsidiaries included in the full consolidation is in line with standard accounting and valuation policies also used for comparative information with the previous year.

Reporting – In accordance with IAS 1.51 (Presentation of Financial Statements) separate classifications of current and non-current assets and current and noncurrent borrowings are shown on the face of the balance sheet.

Evaluations and estimates – For the preparation of consolidated financial statements in compliance with IFRS, it is necessary that estimates and assumptions are made that impact on the amount and disclosure of recognized asset values and liabilities, income and expense. Significant assumptions and estimates are made concerning useful life, earnings attainable from goodwill and non-current assets, realizability of receivables, the recognition and measurement of provisions and realizability of deferred tax assets in respect of loss carry-forwards. The assumptions and estimates are based on the available facts. Because of deviations in the development of these general conditions from the assumptions the amounts included may differ from the original estimates.

Goodwill – Goodwill represents the excess of the aggregate purchase price for an enterprise, or part of one, over the fair value of net assets acquired.

Other intangible assets – Under other intangible assets are shown customer relations, capitalized development costs, patents, trade marks, software, licenses and similar rights. Development costs have been capitalized as intangible assets if the conditions for the capitalization of self-generated intangible assets under IAS 38 have been satisfied cumulatively. Capitalized development costs comprise all directly or indirectly attributable costs incurred from the date on which all the criteria for capitalization have been met. After successful completion of the development project capitalized development costs are depreciated over the anticipated economic life of the product. Research costs, along with development costs not eligible for capitalization, are expensed as they arise.

Intangible assets other than intangible assets with unlimited economic lives are capitalized at acquisition or manufacturing cost and subject to normal straight-line amortization over their respective useful lives (2 to 20 years). Intangible assets with unlimited useful lives are reviewed on a yearly basis to establish whether or not that classification continues to apply.

Value impairment of non-financial assets – Under IFRS goodwill and other intangible assets with unlimited economic lives have to be subject to a test for impairment at least annually, and with other intangible assets and property, plant and equipment this has to be carried out only where there are definite indications that this may have occurred. An impairment loss has to be expensed in cases where the recoverable amount of the asset does not exceed its carrying amount. The recoverable amount is, in principle, to be determined for each asset individually. In cases where a determination on an individual asset basis is not possible, this has to be carried out on the basis of the cash-generating unit to which the asset belongs. The recoverable amount is the higher of net realizable value and utility value. Net realizable value is the amount obtainable from the sale under normal market conditions less the costs of disposal. The utility value is determined on the basis of discounted future net cash flows from the use of the asset. Cash flows used as the basis for the impairment test are estimated, and correspond to those used in long-term business plans.

These impairment tests for 2007 and 2006 showed that there was no need for any non-scheduled depreciation.

Property, plant and equipment – Property, plant and equipment is valued at acquisition or manufacturing cost less accumulated depreciation. The manufacturing costs of self-constructed plant and facilities include all the direct costs and attributable manufacturing overheads. To the extent applicable acquisition or manufacturing costs include the estimated costs of demolition or dismantlement of the asset and restoration of the site. Self-constructed assets mainly relate to production lines. Property, plant and equipment acquired under finance leases within the meaning of IAS 17 are capitalized and depreciated over the estimated useful life of the asset. Other property, plant and equipment and tenant's fixtures acquired through finance leases are depreciated either over the lifetime of the rental or lease or the estimated economic life of the underlying asset, if shorter.

Depreciation expense is determined on the basis of the straight-line method. The depreciation period is fixed in accordance with the foreseeable economic life. The following economic lives are assumed:

Buildings 25 to 45 years
Tenant's fixtures 10 to 15 years
Plant and machinery 4 to 10 years
Fixtures and fittings 3 to 12 years

Upon scrapping or sale the acquisition or manufacturing costs of the assets and the related accumulated depreciation are closed out, and any resulting gain or loss is credited or charged to income.

A significant portion of the Company's depreciable assets is used for the manufacture of its own products. The Executive Board regularly assesses the future usefulness of these assets, taking the business environment at the time into account. On the basis of this assessment no non-scheduled depreciation was necessary in 2007. The Executive Board believes that there was no impairment of utility as of December 31, 2007. It is possible, however, that its estimates concerning the utilization and realizability of the Company's depreciable assets could change in the short term owing to changes in the technological and regulatory environment.

Inventories – Inventories comprise raw materials, consumables and supplies, work in process and finished products. Inventories are stated at the lower of acquisition or manufacturing cost or net realizable value at the balance sheet date. Apart from direct costs, manufacturing costs include appropriate portions of material and manufacturing overheads as well as production-related depreciation, administration and

social costs. Financing costs are not treated as part of acquisition of manufacturing cost. Where necessary, the average cost method is applied in order to simplify valuation.

Write-offs for obsolete or excess inventory are made on the basis of an inventory analysis carried out by the Executive Board and future sales forecasts.

Trade accounts receivable – Trade accounts receivable, such as accounts receivable from the sale of goods and services, are non-derivative financial assets representing fixed or determinable payments and are not listed on any stock exchange or similar market. After their initial recognition in the accounts loans made and trade accounts receivable on the basis of the effective interest method are valued at their net book value less impairment of value. Gains or losses are reflected in the income statement when trade accounts receivable are written off or value-adjusted. Any interest amounts resulting from the application of the effective interest method are also recognized in the income statement.

Investments and marketable securities – Investments in quotes securities are not held for trading or held to maturity. They are, therefore, classified as availablefor-sale financial assets, and measured at fair value based on quoted market prices on the balance sheet date. Unrealized gains and losses arising from subsequent measurement of available-for-sale are entered directly into equity less attributable tax until the securities are sold or an objective impairment is incurred. At this point the cumulative gain or loss is to be recognized as profit or loss for the period.

Derivative financial instruments – Derivative financial instruments such as currency futures or swaps are in principle only used for hedge purposes. They are shown in the Group balance sheet at fair value, with changes in value being passed through the income statement. Apart from an interest-currency swap the Group holds an interest swap (see "Other non-current assets" for details). No further derivatives were held at the balance sheet date.

Liquid assets with restricted availability – Liquid assets with restricted availability refer to amounts paid into a fund by the US subsidiary Eckert & Ziegler Analytics Inc., Atlanta, USA, which are intended to ensure the fulfillment of its future obligations to restore any contaminated plant and facilities.

Certain other cash resources are also subject to restriction, as under the law governing the pre-retirement scheme credits under that scheme have to be protected against the risk of insolvency.

Claims under a life insurance policy serve as pension plan asset in respect of a pension commitment given to a former member of the Executive Board.

The US subsidiary Eckert & Ziegler Isotope Products Inc. has transferred part of their property, plant and equipment by way of security for a bank loan.

A parcel of land of EURO-PET Berlin Zyklotron GmbH has been encumbered with a land charge as security for a bank loan.

We refer to the sections on "Other loans", "Other noncurrent assets" and "Loans" for more details.

Liquid funds – The Company considers all highly liquid funds with a maturity of up to three months to be cash equivalents, to be shown under cash and cash equivalents. In view of their short-term nature the nominal value of these items is taken as their fair value.

Financial liabilities – Financial liabilities include, in particular, accounts payable for goods and services, amounts owed to banks and other liabilities. After their initial recognition in the accounts financial liabilities on the basis of the effective interest method are valued at their net asset value.

Retirement benefit obligation – The valuation of the liability for pensions is based upon the projected unit credit method in accordance with IAS 19, Employee Benefits. Under the projected unit credit method future salary and pension growth is taken into account when measuring the obligation. Actuarial gains and losses are only recognized if they exceed 10 percent of the present value of the obligation (or the plan assets if this is higher). The amount of the surplus is spread over the average expected remaining working period of the employees concerned. A part of the pension obligations is covered by plan assets. As required by IAS 19, the fair value of the amount so covered has been netted against the pension obligations.

Provisions – Provisions are established when there is a current obligation resulting from a past event. Provisions are created in the accounts when the level of their use tends to be more likely than unlikely and the amount used can be reliably estimated. The amount set aside is the best possible estimate of the expense required in order to fulfill the current obligation as of the balance sheet date.

Provisions for environmental restoration – The costs for the demolition and clearance of assets, and also the restoration of the site, are part of acquisition or manufacturing cost under IAS 16, providing the costs have to be provided for under IAS 37.

Provisions for environmental restoration are based on statutory and civil obligations to decontaminate radioactively contaminated assets and buildings, to determine by measurement that they are free from contamination and to allow them to be open to access and general use again without danger. Accordingly, the estimate of costs includes labor costs for the demolition of the facilities, for the preparation of waste so that it can be decontaminated, for the cleaning of rooms and for the disposal of waste by experts, as well as the costs for the disposal and decontamination of radioactive waste. In this, it is only the radioactive waste from the decontamination of assets that is taken into account. Waste that arises from normal production is regularly decontaminated and the associated costs are shown as a separate item within cost of goods sold. Under IAS 37 the environmental costs are measured at current value, i.e. under the assumption that this work is carried out by outside contractors. Provisions are established at the present value of the costs expected as of the balance sheet date. Various assumptions underlie the calculation of the restoration obligations, based on estimates. These include estimates on the labor hours, daily rates and expected material costs required. The amount of the provision allows for expected cost increases until the expense is incurred. The amount of the obligation is reviewed at each balance sheet date, and changes in measurement should be taken up accordingly as adjustments to non-current assets and provisions.

Leasing – If the conditions for a finance lease are satisfied the leased assets in use according to IAS 17 are capitalized as property, plant and equipment and depreciated in full over the life of the leasing agreement. The leasing liabilities are valued at the present value of the lease payments.

Revenue recognition – In accordance with IAS 18, revenue from product sales is realized when performance is complete (generally upon shipment), provided a contractual agreement exists, at a fixed and determinable price, and payment by the customer can be counted on. No guarantees or rights of return are granted to the customer beyond his statutory rights. Licensing fees are recognized in the period to which they relate. For transactions involving several part performances, the revenues are divided between the various performances on the basis of their fair values.

Revenues from operating leases are realized on a straight-line basis over the lifetime of the agreement.

Advertising – Expenditure on advertising and other sales-related costs are charged to expense as incurred.

Research and development – Research expenditure is recognized as expense in the period when it is incurred. Development costs are to be capitalized in accordance with IAS 38 (Intangible Assets) where cumulative conditions are met. Development costs that cannot be capitalized are expensed as they arise. Cost of goods sold includes, apart from costs of materials and labor, also the material and labor burden directly attributable to the development projects.

Income taxes – Deferred tax is calculated by means of the liability method under IAS 12 (Income Taxes). Under this method, deferred tax assets and liabilities are reported in order to reflect future tax impacts attributable to differences between the carrying amounts of assets and liabilities in the Group financial statements and their respective values for tax purposes, as well as from tax loss carry-forwards. Deferred tax assets and liabilities are measured on the basis of statutory tax rates expected to apply to taxable income in the years in which these temporary timing differences are expected to be reversed. The effects of a change in tax rates on deferred tax assets and liabilities are shown in the income statement for the financial year in which the legislative changes were approved. Deferred tax assets are only recognized if it is likely that these asset values will be realized. Deferred tax assets and liabilities are shown net if the corresponding criteria of IAS 12 are fulfilled.

Current income taxes are calculated on the basis of the year's respective national results for tax purposes and the national tax rules.

Share option plan/employee share option scheme –

Accounting for the employee share scheme is in line with IFRS 2 (Share-based Payment). Under this, the fair value of all share options issued has to be established at the time of issue, and spread as staff costs over the vesting period. The fair value of each option issued on the issue date is calculated by means of an option price model. The charge to staff costs is linked to an increase in capital reserves.

Investment grants and other subvention payments – In accordance with IAS 20.7, subvention payments are recognized only if the company satisfies the conditions for award of the grant. Funds that the company receives from public or private sources for investment

or development projects are recorded as deferred income in the financial year of receipt. Grants are offset direct against such expenditure in the period it is incurred. The deferred grants in the Group financial statements were received for the purchase of property, plant and equipment and development costs. They are released to income over the useful lives of the respective property, plant and equipment or intangible assets.

Earnings per share – Earnings or loss per share is calculated by dividing the profit allocated to the shareholders of Eckert & Ziegler AG by the average number of shares in circulation during the financial year. Diluted earnings per share reflect the potential dilution that would occur of all options to acquire shares were exercised at a price below the average share price during the period. It is computed by dividing profit for the year by the sum of the average number of shares in circulation during the financial year plus the diluted shares arising from the exercise of all the outstanding options (calculated by applying the treasury stock method).

New accounting standards

The Group financial statements comply with all the standards of the IASB mandatory in the EU at the balance sheet date, as well as the IFRIC and SIC statements in force. The Executive Board is not anticipating any material effects on future Group financial statements from changes to existing standards made by the IASB under further projects to further develop IFRS and to achieve convergence with US-GAAP, nor from new standards which do not come into force until after December 31, 2007. The following standards and interpretations are not applied in the present financial statements (see table below).

Companies included in the consolidation

In the consolidated financial statements of Eckert & Ziegler AG all companies are included where Eckert & Ziegler AG, either indirectly or directly, is able to determine the financial and business policies (control concept). The companies included in the consolidation as of December 31, 2007 are:

Share of
equity
Eckert & Ziegler BEBIG GmbH, Berlin 100%
Eckert & Ziegler BEBIG Iberia S.L., Madrid, Spain * 100%
Eckert & Ziegler BEBIG Italia s.r.l., Cinisello Balsamo, Italy * 100%
Eckert & Ziegler MMI GmbH, Berlin 100%
STS Steuerungstechnik + Strahlenschutz GmbH, Berlin * 100%
Eckert & Ziegler Isotope Products Inc., Burbank, USA ** 100%
Eckert & Ziegler CNL Scientific Resources Inc.,
San Francisco, USA * 100%
Eckert & Ziegler Analytics Inc., Atlanta, USA * 100%
Eckert & Ziegler Isotope Products GmbH, Berlin * 100%
Eckert & Ziegler Cesio s.r.o., Prague, CZ 80%
Eckert & Ziegler EURO-PET Berlin GmbH, Berlin * 70%
Eckert & Ziegler Radiopharma GmbH, Berlin 100%
Eckert & Ziegler Eurotope GmbH, Berlin * 100%
Eckert & Ziegler f-con Europe GmbH, Holzhausen * 61%
Eckert & Ziegler f-con Deutschland GmbH, Holzhausen * 61%
Eckert & Ziegler f-con Pharma Italia s.r.l.,
Cinisello Balsamo, Italy * 87%
Eckert & Ziegler EURO-PET Köln/Bonn GmbH, Bonn
(formerly: MC Pharma GmbH) * 61%

* indirect interest

** Eckert & Ziegler Isotope Products Inc. has given a commitment to its bank to abide by certain financial covenants. Eckert & Ziegler Isotope Products Inc. may pay a dividend to Eckert & Ziegler AG only if to do so does not breach those covenants.

Changes to companies included in the consolidation

In the financial year 2007 the following shares were acquired and the following changes were made to the companies included in the consolidation:

– Eckert & Ziegler EURO-PET Köln/Bonn GmbH, Bonn: In September 2007 Eckert & Ziegler f-con Deutschland GmbH acquired 100% of the shares of MC Pharma GmbH. The company was then renamed Eckert & Ziegler EURO-PET Köln/Bonn GmbH. – In September 2007 Eckert & Ziegler AG increased its stake in Eckert & Ziegler f-con Europe GmbH from 51% to 61%.

Standard
Description
Mandatory for
financial years
beginning on or after
Application
planned from
Effects on
future
financial
statements
IFRIC 11
IIFRS 2 – Group and Treasury Shares
Transactions Jan. 3, 2007 Jan. 1, 2008 Insignificant
IFRS 8
Operating Segments
Jan. 1, 2009 Jan. 1, 2009 Insignificant

– Also in September 2007 Eckert & Ziegler Cesio s.r.o. and SORAD spol s.r.o. were merged as Eckert & Ziegler Cesio s.r.o.

– In December 2007 Eckert & Ziegler BEBIG GmbH formed an independent marketing subsidiary, Eckert & Ziegler Iberia S.L., in Spain.

Consolidation principles

Consolidation of investments in subsidiaries is carried out in accordance with IFRS 3 (Business Combinations) under the purchase method. Under this, the assets and liabilities acquired are measured at fair value on the date of purchase. Next, the costs of acquiring the purchased shares are netted against the proportionate share of the newly valued shareholders' equity in the subsidiary. A positive difference resulting from this is included under intangible assets as goodwill, a negative difference is included affecting the operating result in the income statement. The initial consolidation is carried out as of the date of purchase.

All significant receivables and payables as well as transactions between related enterprises have been eliminated as part of the consolidation.

4. Currency translation

The financial statements of subsidiaries prepared in foreign currency and included in the Group consolidation are translated into euro in accordance with IAS 21. As the subsidiaries conduct their business affairs autonomously from a financial, economic and organizational standpoint, the functional currency of the companies included corresponds to their respective national currency. Assets and liabilities are translated at mid-market rates on the balance sheet date. To keep things simple, translation of the income statement is at the weighted average rate for the year. Until the subsidiary is disposed of, differences resulting from the translation of the financial statements are not passed through the income statement, but shown as a separate item within equity.

At initial recognition, foreign currency items are measured at historical rates in the annual financial statements of the companies included in the consolidated financial statements. Monetary items are expressed at the mid-market rate as of the balance sheet date. The resultant exchange gains and losses at the balance sheet date are recognized in the income statement. The following exchange rates were used in currency translation:

Average Average
Dec. 31, Dec. 31, rate rate
Currency Country 2007 2006 2007 2006
USA USD 1.471887 1.3203 1.365159 1.255010
CZ CZK 26.6677 27.5344 27.826474 28.236623

5. Limited comparability of group financial statements with the previous year

The changes in the companies included in consolidation during financial years 2007 and 2006 have affected the Group's net assets and result of operations, in part distorting the comparability of the consolidated balance sheet and income statement with the previous year.

In September 2007, Eckert & Ziegler f-con Deutschland GmbH purchased all of the shares in MC Pharma GmbH, Bonn (see the notes given under point 42).

Altmann was deconsolidated as of December 31, 2006, with the result that all balance sheet items of Altmann Therapie GmbH & Co. KG (Altmann in short) were eliminated from the consolidated balance sheet as of that date. Further, the income and expenses from Altmann's deconsolidation were included as profit from discontinued operations for the financial year 2006 (see the notes given under point 21).

Notes on the income statement

6. Revenue

The company generates its income mainly from the sale of goods and, to a lesser extent, from the provision of services and payments for the use of production premises. The revenues have once more gone up in the financial year 2007 from EUR 50,378 thousand to EUR 54,444 thousand. Almost 80% of the increase in growth was due to organic growth, about 20% of the growth coming from business entities newly acquired in financial year 2007.

The classification of revenue by geographical segments and business units is given in the section on segmental reporting.

7. Costs of goods sold

Cost of goods sold includes, apart from costs of materials, labor and depreciation directly attributable to sales, also a proportion of the material and labor

burden and earnings from the liquidation of prepaid expenses.

8. Selling expenses

Expenditure on advertising and other sales-related costs are charged to expense as incurred.

Selling expenses are broken down as follows:

2007 2006
TEUR TEUR
Staff costs 3,935 3,665
Shipping 1,953 1,930
Commission 1,419 787
Advertising 1,023 942
Depreciation and amortization 629 593
Other 1,272 735
Total 10,231 8,652

9. General and administration costs

General and administration costs include:

2007 2006
TEUR TEUR
Staff costs and subsidiary costs 5,453 5,260
Rents 632 568
Depreciation and amortization 1,319 1,259
Earnings from the liquidation
or prepaid expenses -470 -267
Consultancy 722 885
Communications 239 203
Investor relations 193 192
Insurance, subscriptions 371 394
Other 1,994 1,813
Total 10,453 10,307

1 See also point 22 in this document

10. Research and development costs not eligible for capitalization 1

The costs of research, and development costs not eligible for capitalization, have been expensed as incurred and amounted to EUR 289 thousand for 2007 and EUR 333 thousand for 2006. The costs in the research and development areas consist of the following:

  • directly attributable staff and material costs
  • depreciation and amortization
  • other directly attributable expense
  • proportionate burden

The costs of research and development of EUR 289 thousand (2006: EUR 333 thousand) include depreciation and amortization of EUR 155 thousand (2006: EUR 118 thousand), cost of materials of EUR 54 thousand (2006: EUR 108 thousand) and earnings from the liquidation of prepaid expenses of EUR 4 thousand (2006: EUR 3 thousand).

11. Payments to employees and number of employees

The items in the income statement include staff costs of EUR 16,812 thousand (2006: EUR 15,534 thousand).

Staff costs for the financial years 2007 and 2006 are as follows:

2007 2006
TEUR TEUR
Wages and salaries 14,650 13,660
Social security contributions
and expenditure on pensions and
old-age support 2,162 1,991
- of which for pensions 23 62

On average 312 persons were employed by Group companies during 2007. They were working in the following departments:

2007 2006
Production 125 101
R&D/equipment manufacture 43 40
Administration 33 26
Sales and marketing 82 79
Quality management 29 29
Total 312 275

Information on total earnings from current and previous board members and current members of the supervisory board is provided in the remuneration report in the Group management report.

12. Depreciation and amortization

The items in the income statement include depreciation and amortization of EUR 3,731 thousand (2006: EUR 4,537 thousand).

Amortization of intangible assets is included in the following items in the income statement:

2007
2006
TEUR
TEUR
Cost of goods sold
54
52
Selling expenses
192
227
General administrative costs
668
961
Research and dev. costs not
107
eligible for capitalization
69
Total
1,021
1,309

Depreciation of property, plant and equipment is included in the following items in the income statement:

2007 2006
TEUR TEUR
Cost of goods sold 1,574 2,515
Selling expenses 437 366
General administrative costs 651 298
Research and dev. costs not
eligible for capitalization 48 49
Total 2,710 3,228

13. Other operating income

Other operating income essentially includes income from the release of provisions, income from the release of impairment losses and, in reporting year 2007, income from the inclusion affecting the operating result of the negative difference in the first consolidation of Eckert & Ziegler EURO-PET Köln/Bonn GmbH of EUR 120 thousand. Income from the release of provisions in the reporting year was EUR 120 thousand (2006: EUR 127 thousand). In reporting year 2006, income from the repayment of loans from minority interests of EUR 516 thousand was included.

14. Other operating expenditure

Other operating expenditure essentially includes expenditure resulting from impairment losses from claims and losses from the sale of assets.

15. Result from shares valued at equity

On 12.31.2006, Pharmtrace klinische Entwicklung GmbH Berlin was included in the Group accounts using the equity method. In September, Eckert & Ziegler Radiopharma GmbH sold its 30%-share to Pharmtrace GmbH. The equity results were EUR 9 thousand (2006: EUR -9 thousand) and are included in the income statement in the result from shares valued at equity.

16. Remaining net result of financial activities

The remaining net result of financial activities consists of the following:

2007 2006
TEUR TEUR
Gains on currency exchange 595 353
Losses on currency exchange -968 -796
Income from holdings 4 4
Other remaining net result
of financial activities 77 115
Total -292 -324

The market valuation of a derivative security instrument for interest security produced, in 2007, a profit of EUR 77 thousand (2006: EUR 115 thousand), which is included in other remaining net result of financial activities. The market valuation of a derivative security instrument for interest and currency security produced, in 2007, a loss of EUR 13 thousand (2006: profit of EUR 91 thousand), which is included in losses on currency exchange (2006: gains on currency exchange).

17. Interest earnings

Interest and similar income in the financial year amounted to EUR 63 thousand (2006: EUR 74 thousand), while interest expenditure was EUR 830 thousand (2006: EUR 870 thousand).

18. Income tax expense

Under German tax laws income tax expense consists of corporation tax, trade tax and solidarity surcharge.

Loss carry-forwards mainly relate to German companies in the Eckert & Ziegler Group. Losses in Germany can be carried forward indefinitely.

The tax rate for the computation of the tax charge in Germany for corporation tax and trade tax during the financial year was 38.9 percent and 36.8 percent respectively. Tax rates in Germany are as follows:

2007 2006
Trade tax - basic rate 5% 5%
Trade tax -
rate of assessment 330% and 410% 330% and 410%
Corporation tax 25% 25%
Solidarity surcharge
on corporation tax 5.5% 5.5%

Income tax expense/income (-) is made up as follows for the financial years ended December 31, 2007 and 2006:

2007 2006
TEUR TEUR
Profit before tax:
Germany 782 204
Foreign subsidiaries 4,139 4,544
4,921 4,748
2007 2006
TEUR TEUR
Current tax:
Germany 291 92
Foreign subsidiaries 1,514 1,827
1,805 1,919
Deferred tax:
Germany 998 -320
Foreign subsidiaries -32 -365
966 -685
Total taxes: 2,771 1,234
Reclassification into discontinued operations 377
Tax expense as in income statement 2,771 1,611

Reconciliation of the Group's tax expense, based on the tax rates applicable in Germany, to the Group's actual reported tax charge is as follows:

2007 2006
TEUR TEUR
Tax expense based on German tax rates 1,914 1,847
Tax differences on the income
of foreign subsidiaries -279 -444
Actual tax for prior years 21 -28
Disallowable expenditure 243 317
Tax-free income -12 -99
Other items 8 18
Adjustments resulting from tax reform 876 0
Effective tax charge 2,771 1,611

mulgated in Germany. One of the announced changes is the reduction of the rate of corporation tax from 25% to 15% from January 1, 2008. Trade tax will no longer be deductible as a business expense and the basic rate of trade tax is reduced from 5% to 3.5%. The effects of the change in tax law on deferred taxes were to be accounted for in 2007. For German companies a rate of corporation tax of 15% (2006: 25%), a solidarity surcharge of 5.5% on corporation tax and a trade tax rate of 14% (2006: 17%) have therefore been applied. The change in the future tax rate has given rise to an impairment charge of EUR 876 thousand. For foreign companies the prevailing local rates of tax have been applied in calculating deferred taxes.

In 2007 the Enterprise Tax Reform Act 2008 was pro-

Deferred taxes are based upon the differences between the values of assets and liabilities in the consolidated financial statements and those in the tax accounts of individual Group companies, as well as in respect of available tax loss carry-forwards. Deferred tax assets and liabilities have been netted in the balance sheet to the extent permitted under IAS 12.

Deferred tax expense of EUR 1,094 thousand (2006: deferred tax expense of EUR 764 thousand) in respect of tax loss carry-forwards, while deferred tax income of EUR 128 thousand (2006: deferred tax expense of EUR 79 thousand) has been incurred on timing differences. An expense of EUR 74 thousand from currency translation has been offset against this deferred tax income.

During the year under review deferred tax expense of EUR 4 thousand (2006: deferred tax income of EUR 140 thousand) was netted directly within equity without affecting net income.

As part of the initial consolidation of EPK deferred tax assets of EUR 244 thousand and deferred tax liabilities of EUR 22 thousand were recorded. Total deferred tax income of EUR 3,169 thousand (2006: EUR 4,263 thousand) have been capitalized in respect of loss carry-forwards. Of that, EUR 3,136 thousand (2006: EUR 4,212 thousand) may be carried forward indefinitely; the rest is restricted to five years. Deferred tax assets of EUR 1,878 thousand relate to companies in the radiopharmacy segment which suffered another fiscal loss in 2007. Based on the objective in the planning models of continuing to expand activities in this segment and achieving economies of scale in fixed cost degression, the Executive Board anticipates that the deferred tax assets can be fully realized.

Deferred tax assets and liabilities at the individual balance sheet item level are shown in the following table:

Deferred Deferred
tax assets tax liabilities
2007 2006 2007 2006
TEUR TEUR TEUR TEUR
Tax loss
carry-forwards 3,169 4,263 0 0
Non-current assets 522 335 3,293 3,463
Share options 108 183 0 0
Securities 0 0 18 14
Receivables 48 101 133 138
Provisions 1,021 1,327 0 0
Other items 340 138 22 320
Sub-total 5,208 6,347 3,466 3,935
Offsets -2,127 -2,229 -2,127 -2,229
Balance in Group
balance sheet 3,081 4,118 1,339 1,706

The German tax authorities commenced a tax audit in 2004 of Eckert & Ziegler AG for the periods of assessment from 2000 to 2002 which is likely to be completed in the 2008 financial year. The effects of this audit cannot at present be reliably determined since sometimes mutually offsetting effects are at play and individual facts cannot as yet be definitively ascertained.

19. Profit/loss attributable to minority interest

Group profit after tax contains shares of profits amounting to EUR 202 thousand (2006: EUR 324 thousand) attributable to minority interests.

20. Earnings per share

Earnings per share have been calculated as follows:

At end of year
2007 2006
TEUR TEUR
Numerator for the calculation of
earnings and diluted earnings
per share - profit/loss for the year 1,948 2,221
Denominator for the calculation
of earnings per share - weighted
average number of shares (per 1000) 3,142 3,131
Effect of dilutive share options 29 36
Denominator for the calculation of
diluted earnings per share - weighted
average number of shares (per 1000) 3,171 3,167
Basic earnings per share (in EUR) 0.62 0.71
Diluted earnings per share (in EUR) 0.61 0.70

The average share price during the reporting period has been used to determine the dilutive effect of share options.

21. Profit from discontinued operations

The profit from discontinued operations for the previous years included income and expenses arising in connection with the investment in Altmann Therapie GmbH & Co. KG which are broken down as follows:

2007 2006
TEUR TEUR
Revenue 0 3
Cost of goods sold 0 -122
Gross profit on sales 0 -119
Selling expenses 0 -1
General and adminstration expenses 0 -499
Research and development expenses 0 -1,087
Other income 0 157
Other expense 0 -31
Profit fromoperations 0 -1,580
Absorption of losses by
limited partners of Altmann 0 213
Profit beforetax 0 -1,367
Income tax expense 0 377
Annual profit before deconsolidation 0 -990
Income from deconsolidation 0 398
Loss fromdiscontinued
operationsafter tax 0 -592

Notes to the consolidated balance sheet

22. Intangible assets

Under intangible assets are shown goodwill, customer relations, prohibitions to compete, patents and technologies, licenses and software, capitalized development costs as well as other intangible assets.

Intangible assets not subject to scheduled depreciation are mainly goodwill. In addition, other intangible assets with a book value of EUR 1,017 thousand (2006: EUR 753 thousand) are also not subject to any scheduled depreciation due to their unlimited economic lives. These are predominantly trade marks with an unlimited useful life, which are allocated to the segment "Nuclear Medicine and Industry", as well as operational licenses belonging to the segment "Radio Pharmacy". As at December, 31 of the financial years 2007 and 2006 the book values of the intangible assets with unlimited economic lives, which are

not subject to scheduled depreciation, include the following:

2007 2006
TEUR TEUR
Goodwill 9,948 10,773
Others 1,017 753
Total as of Dec. 31 10,965 11,526

The reduction in the value of the intangible assets with unlimited economic lives is mainly linked to the USD/Euro rate of exchange. Most of these intangible assets are included in the balance sheets of the American subsidiaries of Eckert & Ziegler AG, and were converted into the currency applicable to the financial statements (EUR) at the market rate prevailing at December 31 of the financial years 2007 and 2006.

The item Goodwill changed during 2007 and 2006 as follows:

2007 2006
TEUR TEUR
Balance as of Jan. 1 10,733 11,681
Additions 4 35
Currency conversion differences -829 -943
Total as of Dec. 31 9,948 10,773

The allocation of goodwill and the intangible assets with unlimited economic lives to business segments is as follows:

2007 2006
TEUR TEUR
Nuclear medicine and industry 9,950 10,859
Radio pharmacy 1,015 667
Total as of Dec. 31 10,965 11,526

The capitalized goodwill and intangible assets with unlimited economic lives were subjected to an impairment test in accordance with IFRS 3 and IAS 36 in 2007. In this conjunction the goodwill was allocated to cash generating units (CGU). The values attributable to the CGUs as at the reporting date equate to their utility values based on discounted future cash flows. The calculation is based on a current performance measurement for a period of five years. For the subsequent period a growth rate of 1% to 3% was applied to the cash flows. The cash flows were discounted at the Group-uniform weighted average cost of capital of 10.1%. In its determination of the discounting factors the Executive Board relied on external information on the Eckert & Ziegler Group. There was no need to adjust the values of the goodwill or the intangible assets with unlimited economic lives as at December 31, 2007.

The book values of the intangible assets subject to scheduled depreciation were as follows as at December 31 of the financial years 2007 and 2006:

a) Acquired intangible assets

Remaining
depreciation
2007 period 2006
TEUR TEUR
Customer relations 1,668 6-8 years 2,070
Licenses/Software 941 1-7 years 1,207
Patents/Technologies 418 6-17 years 616
Others 152 1-8 years 128
Prohibitions to compete 344 5-6 years 504
Total as of Dec. 31 3,523 4,525

b) Self-constructed intangible assets

2007 Remaining
depreciation
period
2006
TEUR TEUR
Capitalized
development costs 3,746 5-11 years 1,934
Total as of Dec. 31 3,746 1,934

During the financial year 2007 development costs totaling EUR 1,854 thousand (2006: EUR 1,483 thousand) were capitalized. The item development costs as at December 31, 2007 and 2006 included the following:

2007 2006
TEUR TEUR
Equipment for radio
pharmaceutical synthesis 2,362 1,493
Pulsed dose rate radiotherapy 1,120 379
Pharmgrade Generator 220 0
Others 44 62
Total as of Dec. 31 3,746 1,934

The completion of the "Pulsed Dose Rate Radiotherapy" unit is not on schedule and will probably be delayed until mid-2008. Consequently, the first substantial sales revenues from this new development are not anticipated until 2009 and as a result an impairment test was performed as at December 31, 2007. The total present value of the future cash flows generated by the use of the asset (utility value) was calculated on the basis of a discounting factor of 10%. It was established that this utility value exceeded the book value of the capitalized development costs thus obviating the need for any value adjustment. If the development is delayed further and sales are not achieved as planned there may be a need for a value adjustment in 2008. At present the Company assumes that the development will be completed on schedule and that no value adjustment will be required.

The equipment for the radio-pharmaceutical synthesis was completed in December 2007 and is scheduled to be depreciated over a period of 5 years. The other capitalized development costs are not currently being depreciated, as the development of the systems has not been finalized and the assets, therefore, cannot by used by the Company as yet. In the income statement the depreciation on intangible assets has been allocated on the basis of the functional area of the relevant intangible assets to manufacturing costs, sales costs, research and noncapitalized development costs or general administrative costs (see also notes under point 12).

The movements of the intangible assets between January 1 and December 31, 2007 are shown in the fixed asset movement schedule.

23. Property, plant and equipment

Movements in property, plant and equipment from January 1 to December 31, 2007 are shown in the non-current assets movement schedule.

Assets which have been acquired by way of finance leases are included in property, plant and equipment. Net book values of assets accounted for as finance leases amount as of December 31, 2007 to EUR 237 thousand (2006: EUR 316 thousand).

In addition to current replacement investments, the additions during financial year 2007 mainly concern expansion of existing production plant.

In line with IAS 23 the allowed alternative treatment has been applied in the recognition of borrowing costs. Under this, borrowing costs that are directly

attributable to the acquisition, construction or production of a qualifying asset are capitalized as part of the cost of the acquisition or manufacturing cost of that asset. Capitalized interest amounted to EUR 0 thousand and EUR 12 thousand in 2007 and 2006 respectively. Borrowing costs eligible for capitalization were based on a cost of capital of 11.56 percent.

Own work capitalized totaled EUR 0 thousand (2006: EUR 130 thousand) in the year. Net book values of the internally generated assets in property, plant and equipment amount, as of December 31, 2007 to EUR 1,507 thousand (2006: EUR 2,245 thousand).

24. Other loans

Other loans relate to rental deposits of EUR 29 thousand (2006: EUR 31 thousand) and cash paid into a decontamination fund of EUR 15 thousand (2006: EUR 17 thousand). Payments into the fund relate to future obligations to decommission and restore plant and facilities belonging to Eckert & Ziegler Analytics Inc., Atlanta, USA. These amounts are prescribed by law, are under state control and their access is therefore restricted.

25. Other non-current assets

Other non-current assets include an interest-currency swap of EUR 954 thousand (2006: EUR 967 thousand) and an interest swap of EUR 181 thousand (EUR 104 thousand shown under other current assets). These are derivatives recognized in accordance with IAS 39.9 as financial assets affecting the current period at fair value. Further information on these derivative financial instruments can be found in the notes under point 38.

Contractual rights to reimbursement in connection with environmental restoration provisions of EUR 352 thousand (2006: EUR 327 thousand) are shown under other assets.

In addition, cash equivalents of EUR 85 thousand (2006: EUR 141 thousand), which are intended to protect credits under the pre-retirement scheme against the risk of insolvency, as required by the law governing that scheme, are shown under other assets. The cash is subject to restricted access.

26. Cash and cash equivalents

Cash and cash equivalents of EUR 4,375 thousand (2006: EUR 4,683 thousand) are represented by checks, cash in hand and cash at banks maturing within three months.

27. Securities

All of the securities are classified as available for-sale financial assets. The following summary shows the composition of securities as of December 31,2007 and 2006:

Dec. 31, 2007
Unrealized Unrealized
Costs gains gains Fair Value
TEUR TEUR TEUR TEUR
Bonds 176 4 -2 178
Investment funds 797 68 -10 855
Total marketable
securities 973 72 -12 1,033
Dec. 31, 2006
Unrealized Unrealized
Costs gains gains Fair Value
TEUR TEUR TEUR TEUR
Bonds 248 6 -3 251
Investment funds 797 42 -9 830
Total marketable
securities 1,045 48 -12 1,081

The fair value of securities is determined by quoted prices.

Bonds have a remaining period to redemption of between 2 and 16 months as of December 31, 2007.

28. Trade accounts receivable

Trade accounts receivable consist of the following items as of December 31, 2007 and 2006:

2007 2006
TEUR TEUR
Trade accounts receivable 11,968 11,553
Less allowances -509 -443
Balance as of Dec. 31 11,459 11,110

29. Inventories

Inventories consist of the following items as of December 31, 2007 and 2006:

2007 2006
TEUR TEUR
Raw materials, consumables and supplies 6,073 4,826
Finished products 1,505 954
Work in progress 322 274
7,900 6,054
Less allowances for obsolescence -187 -166
Balance as of Dec. 31 7,713 5,888

Raw materials, consumables and supplies mainly consist of nuclides and components needed for the fabrication of end products.

Adjustments made on the basis of a comparison of net realizable value against book value increased by EUR 21 thousand.

30. Other short-term assets

The item Other Short-term Assets amounting to EUR 2,200 thousand (2006: EUR 1,204 thousand) mainly includes deferrals, prepayments made, amounts owed by tax authorities and loans made.

The directors of Eckert & Ziegler Cesio s.r.o., who are also minority shareholders, were each granted a loan by Eckert & Ziegler AG. As at December 31, 2007 the amounts owed, including interest, were EUR 499 thousand (2006: EUR 489 thousand). The loans are due for repayment on September 30, 2008 and were, therefore, re-classified as short-term assets.

31. Shareholders' equity and minority interest

The movements of the shareholders' equity and the minority interest are shown in the equity movement schedule.

On June 12, 2007 the Annual General Meeting resolved to use the net profit of Eckert & Ziegler for the previous year amounting to EUR 1,170 thousand to pay a total dividend of EUR 786 thousand or EUR 0.25 in respect of each eligible share certificate and to allocate an amount of EUR 385 thousand to other revenue reserves.

The share capital of the Company amounted to EUR 3,250,000.00 as at December 31, 2007 and is divided into 3,250,000 fully paid-up nonpar shares.

According to the German Aktiengesetz any dividend that may be distributed to the shareholders has to relate to the net profit for the year shown in the financial statements that are based on German commercial law. The AGM has been asked to pay the shareholders a dividend of EUR 786 thousand (0.25 EUR per share) out of the net profit of Eckert & Ziegler AG for 2007.

Authorized capital

Through a resolution of the shareholders' meeting on May 30, 2006 the Executive Board was authorized, with the approval of the Supervisory Board, to increase the company's nominal capital by up to EUR 1,625,000 by issuing up to 1,625,000 bearer shares for cash or non-cash contributions, while excluding the subscription rights of existing shareholders where relevant (authorized capital).The Executive Board is authorized, with the approval of the Supervisory Board, to determine any further rights attaching to the shares and the conditions for the share issue. The exclusion of subscription rights is permissible for capital increases with non-cash contributions, particularly for the acquisition of enterprises or parts thereof, equity investments in enterprises or patents. For capital increases against cash contributions, exclusion of subscription rights is only permissible to the extent that it is necessary for the equalization of highestranking amounts, or if the capital increase does not exceed 10 percent of the nominal capital, and the issue price of the new shares does not lie significantly below the stock market price of the shares at the time that the Executive Board determines the issue price. The authorization is valid until June 30, 2009.

Contingent capital

The nominal capital has been conditionally increased by up to a further EUR 300,000.00 (authorized but unissued share capital), split into a maximum of 300,000 shares. The increase in contingent capital is only implemented subject to the holders of share options, which the Executive Board was authorized to issue by the shareholders' meeting held on April 30, 1999, using their rights to subscribe to shares in the company and the company not fulfilling the option rights by the transfer of its shares or by making a cash payment.

Reserves

Reserves consist of unappropriated past earnings of consolidated Group companies.

In addition, reserves include adjustments resulting from the first application of the IFRS. Reserves also include conversion differences of EUR 3,776 thousand (2006: EUR 2,701 thousand) resulting from the conversion of the financial statements of the foreign subsidiary.

Also included in the reserves are value changes of the available-for-sale securities (after tax) amounting to EUR 42 thousand (2006: EUR 22 thousand) that do not affect the operating result. During the reporting period expenses of EUR 104 thousand (2006: EUR 116 thousand) associated with the issue of share options were also included in the reserves.

Own shares

As part of a share buyback scheme the company bought a total of 320,000 of its own shares in March 2003 (about 9.8 percent of nominal capital) at an average price of EUR 3.35 per share.

In October 2003, 5,503 of these shares were resold. The acquisition in 2004 of Eckert & Ziegler MMI GmbH and Eckert & Ziegler Isotope Products GmbH was financially partly using the company's own shares. To do so, a total of 139,648 of the company's own shares were applied. Up to now, 51,000 own shares (2007: 2,700 shares, 2006: 2,900 shares, 2005:32,000 shares, 2004: 13,400 shares) have been utilized to service share options under the employee share scheme. In financial year 2007, 200 of the company's own shares, which were used for servicing employee stock options, were repurchased on the Stock Exchange.

Transactions in own shares gave rise to a total profit in 2007 of EUR 12 thousand (2006: EUR 170 thousand), which was appropriated to the capital reserve for own shares with no effect on net income. The balance of own shares stood at 106,835 shares as of December 31, 2007. This corresponds theoretically to a share of 3.3% of the company's share capital.

Changes in the number of outstanding share options are shown in the Other Information section.

The number of shares in circulation in the 2007 and 2006 financial years was as follows:

2007 2006
Units Units
Balance as of Jan 1 3,140,665 3,120,551
Utilization of own shares to
service employee options or
for acqisitions 2,700 20,114
Return of own shares
(share buyback scheme) -200 0
Balance as of Dec. 31 3,143,165 3,140,665

32. Borrowings and financial leasings

Borrowings consist of the following items as of December 31, 2007 and 2006:

2007 2006
TEUR TEUR
Bank borrowings 5,803 7,283
Other borrowings 6,374 3,401
Balance as of Dec. 31 in total 12,177 10,684
- of which current 8,256 3,365
- of which non-current 3,921 7,319

The following table gives an overview of borrowings as of December 31 in each of the financial years:

2007 2006
Interest rate p.a. TEUR TEUR
Loans from former shareholders
resulting from takeover
of shares 4% to 6.5% 5,203 2,394
Loans from Deutsche
Industrie Bank AG (IKB) 8,6% plus 3% on
realization of profit 1,795 1,776
Loans from
Landesbank Berlin 4.85% to 5.72% 1,008 1,480
Loans from minority
interest shareholders 5.00% 852 811
Loan from
Comerica Bank (USA) 6.50% 504 784
Loan from
Deutsche Bank AG 3-month
EURIBOR + 1% 1,750 2,000
Other overdraft facilities variabel 50 131
Reconstruction credit loan
from Commerzbank AG 7.38% 306 454
Other loans 4.0% to 9.8% 709 854
Total borrowings as of Dec. 31 12,177 10,684

In the 2007 financial year borrowings increased again compared with the previous year. This increase can essentially be attributed to the acquisition of Eckert & Ziegler EURO-PET Köln/Bonn GmbH as part of which a loan of EUR 3,084 thousand payable by the company to the former shareholders was assumed. This loan is due for repayment by December 31, 2008.

The loan payable to the Deutsche Industriebank AG (IKB) in the original amount of EUR 2,812 thousand extends over 10 years and is repayable on June 30, 2008. Early redemption is possible subject to an early payment penalty. In the event of Eckert & Ziegler AG's insolvency, IKB has secured a subordination of its receivables.

The loans granted by the Landesbank Berlin to EURO-PET Berlin Zyklotron GmbH are secured by a mortgage of EUR 1,534 thousand on EURO-PET Berlin Zyklotron GmbH's business premises in Berlin and a guarantee from Eckert & Ziegler AG. The loan from Comerica Bank to Eckert & Ziegler Isotope Products, Inc. (IPL) is secured by an assignment of IPL's noncurrent assets.

IPL has been granted a credit line by a bank of up to USD 4,500 thousand (EUR 3,057 thousand). In addition, there is a further credit facility in the form of a guarantee for up to USD 1,875 thousand (EUR 1,274 thousand) which has been utilized as security for the decontamination plan.

Eckert und Ziegler AG and its German subsidiary have joint credit lines available of EUR 4,075 thousand of which EUR 1,800 thousand has been utilized.

The interest rate agreed for the loan of EUR 1,750 thousand granted by Deutsche Bank was the threemonth EURIBOR rate + 1 percent at the time of taking up the credit. The risk of an interest rate change was hedged by means of an interest swap, so that the effective rate is 4.5 percent.

The remaining periods to maturity of the borrowings on December 31, 2007 and 2006 are as follows:

2007 2006
TEUR TEUR
Up to 1 year 8,256 3,365
1 to 5 years 3,921 7,319
Over 5 years 0 0
Total borrowings as of Dec. 31 12,177 10,684

33. Deferred income from grants and other deferred income

The item "Deferred income from grants and other deferred income" is made up of the following as of December 31 in each of the years:

2007 2006
TEUR TEUR
Current deferred income from grants 859 873
Other deferred income 76 87
Current deferred income from
grants and other deferred income 935 960
Non-current deferred income
from grants 1,369 1,270
Balance as of Dec. 31 2,304 2,230

34. Retirement benefit obligations

Pension undertakings have been made for a former member of the Management Board as part of the company's old-age provision which is based on a defined benefit pension plan. Pension obligations are calculated in accordance with IAS 19 under the projected unit credit method by taking the present value of pension benefits earned up to the measurement date, including probable future increases in pensions. The determination of present value involves using a discount rate of 5.25 percent (2006: 4.5 percent). As the person concerned will already have left company service, the scale of the obligation changes annually merely with the interest compounded and with actuarial gains and losses. This produced the following obligations determined actuarially in each of the financial years ending December 31:

2007 2006
TEUR TEUR
Present values of defined benefit
retirement obligations 384 398
Plan assets at fair value -302 -253
Actuarial gains (+) and losses (-) 16 -16
Retirement benefit obligations as of Dec. 31 98 129

The amounts shown for retirement benefit obligations have changed as follows:

2007 2006
TEUR TEUR
Retirement benefit obligations
as of Jan. 1 129 128
Payments of pensions 18 16
Allocation of actuarial losses
(+) and gains (-) 0 18
Payments into the fund or
plan assets -27 -27
Interest receivable on plan assets -22 -6
Retirement benefit obligations as of Dec. 31 98 129

The following amounts were recognized in the income statement in each of the financial years:

2007 2006
TEUR TEUR
Interest expense 18 16
Allocation of actuarial
losses (+) and gains (-) 0 18
Income from the fund or
plan assets -22 -6
Total amounts recognized -4 28

A pension plan is also in place for a current board member and designed as an employee-financed contributory defined benefit (deferred compensation). The level of deferred compensation for the pension plan amounted to EUR 100 thousand in 2007 (2006: EUR 0 thousand). The defined benefit is financed through a fully covered relief fund.

35. Other non-current liabilities

The main element of other non-current liabilities is the provision pursuant to IAS 37.

The following table gives an overview of the movements in other non-current liabilities in 2007 and 2006.

2007 2006
TEUR TEUR
Environmental
restoration provisions 3,478 3,062
Other 175 387
Other non-current liabilities as of Dec. 31 3,653 3,449

Movements in the provisions for environmental restoration in 2007 are as follows:

2007 2006
TEUR TEUR
Environmental restoration
provisions as of Jan. 1 3,062 3,466
Additions/ retirements 405 -386
Compounding interest 146 151
Currency translation -135 -169
Environmnetal restoration
provisions as of Dec. 31 3,478 3,062

For valuation of environmental restoration provisions in 2007 an adjustment has been made to align discount rates to changes in the capital markets, in accordance with IFRIC 1. These adjusted interest rates lie between 4.0 and 4.7 percent. Retaining the previous year's interest rates of 4.5 to 4.7% would have resulted in a provision for environmental restoration which was EUR 8 thousand lower.

For some sites amounts have been paid into a fund whose use is restricted to future restoration. These payments are shown under other loans and amount to EUR 15 thousand (2006: EUR 17 thousand). Contractual rights to reimbursement in connection with obligations for restoration in an amount of EUR 352 thousand (2006: EUR 327 thousand) are shown under other non-current assets.

36. Provisions

Short-term provisions have changed in 2007 as follows (see table below):

37. Other current liabilities

Other current liabilities are composed of the following as of December 31 in each year:

2007 2006
TEUR TEUR
Liabilities to associated persons
and companies 0 6
Other short-term liabilities 1,633 1,184
Balance as of Dec. 31 1,633 1,190

The remaining short-term liabilities primarily include interest, wages and salaries, social security and payroll tax.

38. Additional information on financial instruments

This section gives an overview of the importance of financial instruments for Eckert & Ziegler AG and provides additional information on the balance sheet positions containing financial instruments.

Overview of financial assets and liabilities

The following table shows the book values of all categories of financial assets and liabilities:

2007 2006
TEUR TEUR
Financial assets
Cash and cash equivalents 4,375 4,683
zur Veräußerung verfügbare
Financial assets available for sale 1,033 1,081
Loans and receivables 13,364 12,786
Derivative financial instruments 1,135 1,071
19,907 19,621
Financial liabilities
Financial liabilities relating to
continued acquisition costs 18,160 16,445
18,160 16,445

Loans and receivables are made up as shown in table A on the next page.

2006 Utilized Addition Release 2007
TEUR TEUR TEUR TEUR TEUR
Accruals for profit-sharing and bonuses 1,127 1,091 1,477 36 1,477
Other staff-related accruals 713 712 830 1 830
Accruals for ground rent 226 0 9 0 235
Accruals for year-end audit 75 71 109 4 109
Accruals for Supervisory Board fees 62 62 64 0 64
Other provisions and accruals 1,768 1,689 2,424 79 2,424
Provisions as of Dec. 31 3,971 3,625 4,913 120 5,139

The financial liabilities relating to continued acquisition costs are composed as shown in table B (see below):

The breakdown of loan obligations and finance lease obligations is illustrated in point 32.

Fair values of financial assets and liabilities

The following table shows the fair values and the book values of the financial assets and liabilities which are valued at initial costs or continued initial costs:

2007 2006
Fair value book value Fair value book value
TEUR TEUR TEUR TEUR

Financial assets valued at initial costs or continued initial costs

Cash and cash
equivalents 4,375 4,375 4,683 4,683
Receivables from
goods and services
and other receivables 11,459 11,459 11,110 11,110
Other non-derivative
financial assets 1,905 1,905 1,676 1,676
17,739 17,739 17,469 17,469
2007 2006
Fair value book value Fair value book value
TEUR TEUR TEUR TEUR
Financial liabilities valued at initial costs or continued initial costs
Trade accounts payable 3,885 3,885 3,860 3,860
Obligations to credit
institutions and other
financial indebtedness 12,063 11,958 10,605 10,386
Obligations from
finance leasing 219 219 298 298
Other non-derivative
financial liabilies 2,098 2,098 1,901 1,901
18,265 18,160 16,664 16,445

The fair value of cash assets and cash asset equivalents, of short-term credits, of trade accounts payable and of other short-term liabilities is approximately equivalent to the book value. The reason for this is primarily the short term of such instruments.

The company determines the fair value of obligations to credit institutions and other financial indebtedness, obligations arising from finance leasing and other long-term financial obligations by deducting from the expected future payment flows the interest applying for similar financial debts with a comparable remaining term.

Table A

2007 2006
TEUR TEUR
Receivables for goods and services short-term 11 ,459 11,110
Claims against associated persons
and companies long-term (as of Dec. 31, 2007 short-term) 503 516
Claims against the Tax Office short-term 471 76
Claims in the event of recourse long-term 352 327
Other receivables long-term / short-term 579 757
13,364 12,786
Table B
2007 2006
TEUR TEUR
Loan obligations short-term 8,172 3,146
Loan obligations long-term 3,786 7,240
Finance lease obligations short-term 84 79
Finance lease obligations long-term 135 219
Trade accounts payable short-term 3,885 3,860
Liabilities to staff short-term 375 100
Other liabilities short-term 1,547 1,415
Other liabilities long-term 176 386
18,160 16,445

The following table shows the financial assets and liabilities valued at the fair value:

2007 2006
TEUR TEUR
Financial assets valued at the fair value
Financial assets available for sale 1,033 1,081
Derivative financial instruments 1,135 1,071
2,168 2,152

Risk analysis

In the course of its operational activities, the Group is exposed to credit, liquidity and market risks in the finance sector. Market risks relate in particular to interest rate changes and foreign exchange risks.

Credit risk

Credit risk or risk of non-payment is the risk that a customer or contractor of the Eckert & Ziegler group cannot meet its contractual obligations. The result of this is on the one hand the risk of depreciation of financial instruments due to issues of solvency and on the other hand the risk of partial or complete loss of contractually agreed payments.

For the Group a possible credit risk arises essentially from its receivables from goods and services. Exposure is primarily influenced by the size of the customer and region-specific regulations and customs for handling the reimbursement of medical services by public authorities.

In general a rating is obtained for new customers and initial deliveries are in principle made against cash in advance. For deliveries to customers who because of their size or location are regarded as permanently unreliable, cash in advance or letters of credit are used as a safeguard.

As part of the group-wide risk management, the credit risk is monitored by means of regular analysis of overdue payments of all receivables from goods and services..

Exposure:

The maximum loss risk corresponds to the book value of the financial assets on the balance-sheet date in an amount of EUR 15,532 thousand (2006: EUR 14,938 thousand).

With the exception of receivables for goods and services the balance sheet does not contain any overdue or depreciated financial assets. The Company estimates the loss risk of these other financial assets as very low.

The maximum credit exposure at the date of the annual accounts with respect to receivables from goods and services was, by geographical regions, as follows:

2007 2006
TEUR TEUR
Europe 7,449 7,236
North America 3,031 2,372
Other 983 1,529
11,463 11,137

The age structure of due, but not depreciated receivables is shown as at December 31, 2007 as follows:

2007
TEUR
Not due 6,331
1 to 90 days 3,157
Over 90 days 1,975
11,463

The overdue, but not yet depreciated receivables relate essentially to claims on doctors' practices and foreign clinics. On the basis of past experience, inpayment is expected at the above-mentioned level.

Customer-specific details are used to determine the depreciation on receivables from goods and services. The movement in depreciation on receivables from goods and services is shown below:

2007 2006
TEUR TEUR
443 512
90 34
-15 -96
-9 -7
509 443

Liquidity risk

The liquidity risk is the risk that the Group is not able to meet its financial obligations on time. The aim and function of liquidity management is to ensure that the provision of borrowed funds and capital resources is always adequate.

As part of financial planning, a liquidity forecast is produced from which among other things it is possible to identify the borrowed fund financing requirement in advance.

The Group generates its financial means mainly from its operating business. Eckert & Ziegler AG and its subsidiaries have at their disposal credit lines amounting to EUR 7,132 thousand (2006: EUR 6,027 thousand) if required for this purpose. In some cases new thirdparty financing is taken up according to the above framework conditions for extraordinary investments and acquisitions and to repay due loans.

As at the date of the annual accounts the consolidated balance sheet shows various short-term and long-term obligations also to credit institutions. For the future liquidity of the company, it is necessary for this third-party financing to continue and for it to be refinanced in the short term.

In principle it should be noted that the Group has an equity ratio of 54% and therefore in principle it is possible for the level of borrowing to increase. The Executive Board has not identified any effects from the subprime crisis on the Group. The Company has various

offers of new financing and refinancing from which it is apparent that future financing is ensured.

From the possibilities for third-party financing and the predicted liquidity requirement it can be deduced that the company has adequate financial means at the present time to be able to secure its existence and its further development. It also sees itself in a position to fulfil all its payment obligations even if a slight increase in the debt ratio were necessary in coming financial years in order to be able to ensure growth by means of additional acquisitions and finance development of new products.

Exposure:

The contractually agreed due dates for financial obligations including interest payments are shown in the tables A and B below:

An interest rate in 2007 of 4.76 per cent (2006: 4.49 per cent) is used as the basis for payment outflows for variable-interest-rate obligations.

Foreign exchange risks

The Group's international business activity exposes it to foreign exchange risks which result from the influ-

Table A 2007

Analysis of contractually agreed due dates Cash outflow
Total Up to 1 year 1 to 5 years Over 5 years
TEUR TEUR TEUR TEUR TEUR
Loan obligations fixed interest rate 10,151 11,315 6,662 4,507 146
Loan obligations variable interest rate 1,807 1,893 1,893 0 0
Finance lease obligations fixed interest rate 219 280 113 113 54
Trade accounts payable interest-free 3,885 3,885 3,885 0 0
Obligations to staff interest-free 375 375 375 0 0
Other liabilities interest-free 1,723 1,723 1,547 160 16
18,160 19,471 14,475 4,780 216
Table B 2006
--------- ------
Analysis of contractually agreed due dates Cash outflow
Total Up to 1 year 1 to 5 years Over 5 years
TEUR TEUR TEUR TEUR TEUR
Loan obligations fixed interest rate 8,255 9,543 2,110 7,333 100
Loan obligations variable interest rate 2,131 2,227 1,499 728 0
Finance lease obligations fixed interest rate 298 331 92 239 0
Trade accounts payable interest-free 3,860 3,860 3,860 0 0
Obligations to staff interest-free 100 100 100 0 0
Other liabilities interest-free 1,801 1,801 1,415 374 12
16,445 17,862 9,076 8,674 112

ence of exchange rate fluctuations on business and assets and liabilities denominated in foreign currency (transaction risks). The main foreign currency transactions in the Eckert & Ziegler Group concern the US dollar as a result of loan repayments of the American subsidiaries and export business of the German subsidiaries. The effect is only partially compensated by the operating activity of a subsidiary which buys mainly in US dollars and sells mainly in Euros. In addition to US dollars there are further surpluses of foreign currency as a result of exports in the foreign currencies, Japanese yen, Polish zloty and Swedish krone. In these currencies there are virtually no cost positions so that the complete conversion into foreign currency is exposed to the currency risk.

Various measures counter the above-described transaction risks. The loans to the American subsidiaries are in some cases secured by an interest-foreign currency swap on the following conditions:

Interest-currency swap
Transaction date: Feb. 8, 2001
Start date: Feb. 12, 2001
End date: Jan. 31, 2011

As at the balance-sheet date, the Company still has a payment obligation arising from this business amounting to USD 2,315 thousand (2006: USD 2,604 thousand)

at a fixed interest rate of 10.0% p.a. Against this it receives EUR 2,497 thousand (2006: EUR 2,809 thousand) at a fixed interest rate of 8.77% p.a. The fair value of this swap business as at 12.31.2007 is EUR 954 thousand (2006: EUR 967 thousand). The expenditure from the change in market valuation has been shown under foreign currency losses. The Company was notified of the fair value by the credit institution with which it had concluded the swap business. According to a statement by the credit institution, all EUR and/or USD cash flows have been discounted, added and balanced using the relevant zero interest rates (calculated from the current EUR and/or USD interest rate trends) to determine the current cash value of cross-currency swaps (EURUSD; fix against fix). For this purpose the USD cash flows have been converted into EUR using the current EUR-USD exchange rate. The resulting balances then show a positive and a negative cash value from the existing contractual relationship for the contractors.

Export business in Japanese yen and Polish zloty are guaranteed by means of foreign currency options and forward business. As at the balance-sheet date there were no open positions arising from foreign currency forward and option business.

Exposure:

The exposure of the Group in respect of transaction risk as at the date of the annual accounts was as follows (see table below):

Foreign currency exposure
Converted to thousand EUR 2007 2006
USD CHF SEK USD CHF YEN
Cash 212 118 242 60
Receivables from goods and services 977 44 18 452 40 181
Trade accounts payable -47 -61
Balance-sheet exposure 1,142 162 18 633 100 181
Contractual payment obligations
from interest-currency swap -1,573 -1,972
Net exposure -431 162 18 -1,339 100 181

Sensitivity analysis

As at the date of the annual accounts an increase in the Euro of 10% compared with the following currencies would have led – subject to otherwise unchanged assumptions – to the increases (decreases) in equity and the annual result indicated as follows:

Effect in thousand EUR 2007 2006
USD CHF SEK USD CHF YEN
Equity 0 0 0 0 0 0
Annual result 39 -15 -2 122 -9 -16

As at the date of the annual accounts, a reduction in the Euro of 10% compared to the above-mentioned currencies would have led to an identical, but opposite effect on the currencies mentioned.

The currency conversion rates indicated under item 4 have been used as the basis for the sensitivity analysis.

Interest rate risks

The Group is exposed to risks in interest rate changes essentially in the area of medium-term to long-term financial assets and liabilities subject to interest as a result of fluctuations in market interest rates.

No safeguarding measures have been taken for items which cause no payment effect in the event of interest rate changes.

In order to limit the risk of interest rate changes when procuring short-term credit the Company arranged an interest swap with a maturity of 12 years in October 2005. A purchase amount of EUR 2,000 thousand at a fixed interest rate of 3.53% was secured. For this Eckert & Ziegler AG pays a fixed quarterly amount of EUR 17,650 until October 2017. Against this, the bank pays variable amounts quarterly (in each case the 3 month EURIBOR) until the agreement has expired. The fair value of this swap business as at 12.31.2007 is EUR 181 thousand (2006: EUR 104 thousand) and is shown in the balance sheet under other long-term assets. The income from the change in market valuation has been shown in the profit and loss account under other sundry financial results. The credit institution with which the swap business was concluded notified the Company of the fair value. According to a statement by the credit institution, all payments to be made by the customer or the bank calculated from the valuation date to the end of the agreement have been discounted, added and balanced on the basis of the current interest structure trend in order to determine the current cash value of the interest swap. The variable interest payments (EURIBOR) were deducted on the basis of the forward interest rates for the corresponding period calculated from the current interest structure trend. The resulting balances then show a positive and a negative cash value from the existing contractual relationship for the contracting parties.

Exposure:

As at the balance-sheet date, the Company has the following medium-term and long-term interest-bearing assets and liabilities:

Medium-term and long-term

interest-bearing assets and liabilities 2007 2006
TEUR TEUR
Interest-bearing financial assets 3,020 2,968
of which variable interest rate 1,208 1,158
of which fixed interest rate 1,812 1,810
Interest-bearing financial liabilities 12,177 10,684
of which variable interest rate 1,807 2,131
of which fixed interest rate 10,370 8,553

Sensitivity of the fair values for fixed-interest financial instruments:

Assets available for sale amounting to EUR 178 thousand (2006: EUR 248 thousand) are shown under fixed-interest assets. A fall in the market interest rate in a margin of 100 base points would have led to an increase of the fair value by EUR 2 thousand (2006: EUR 3 thousand) which would have been recorded in equity. An increase in the market interest rate in a margin of 100 base points would have resulted in a reduction in the fair value or equity by EUR 2 thousand (2006: EUR 3 thousand).

Furthermore the interest and currency swap and the interest swap are shown under fixed-interest financial assets. A fall in the market interest rate by 100 base points would – with otherwise the same assumptions – result in a reduction of the fair value and hence the annual result by EUR 131 thousand (2006: EUR 141 thousand). An increase in the market interest rate by 100 base points would result in an increase in the fair value and/or the annual result by EUR 129 thousand (2006: EUR 117 thousand).

All other fixed-interest financial instruments are valued at continued acquisition costs. Therefore a change in the market interest rate would not have affected the valuation of these financial instruments as at the balance-sheet date.

Sensitivity of payment flows for variable-interest financial instruments:

Taking into account the interest swap arranged, a rise in the market interest rate of 100 base points as at the date of the annual accounts would result – subject to otherwise unchanged assumptions – in the increases (decreases) in the annual result given below:

Effect in thousand EUR 2007 2006
+100 -100 +100 -100
base base base base
points points points points
Interest result
for variable
interest financial
instruments -5 5 -13 13
Safeguarded by
interest swap 20 -20 20 -20
Net effect
on annual result 15 -15 7 -7

Capital management

Capital at risk forms the basis for capital management. All lendings, investments and guarantees which Eckert & Ziegler AG has given to and/or for subsidiaries are used for this purpose. The EBIT of the segment is compared with the capital at risk. The quotient from both values gives the return on capital at risk. The trend of this risk for the segments is observed by the Executive Board over the course of time and used for backward-oriented valuations and forward-oriented targets.

Eckert & Ziegler AG (parent company) is subject to the provisions of company and commercial law in Germany of minimum capitalisation in accordance with paragraph 92 of the AktG (Companies Law). According thereto an extraordinary general meeting must be called if the sum of the equity under commercial law of the parent company falls below 50% of the share capital. This did not occur in the financial year 2007.

Notes on the group cash flow statement

Cash and cash equivalents shown in the Group cash flow statement are represented by cash in hand, checks, cash at banks and all highly liquid cash equivalents maturing within three months.

The Group cash flow statement depicts how cash balances in the Eckert & Ziegler Group have changed by cash inflows and outflows in the course of the financial year. In accordance with IAS 7 (Cash Flow Statements) cash flows in the Group cash flow statement have been split under cash inflows from operating, investing and financing activities.

39. Operating activities

Starting with profit after tax the cash inflows and outflows are determined indirectly. Profit/loss after tax is adjusted for expense not involving the movement of cash and supplemented by changes in assets and equity and liabilities.

40. Investing activities

Cash flows from investing activities are derived from actual payment transactions. They include cash flows in connection with the acquisition and disposal of non-current assets and marketable securities which do not form part of cash and cash equivalents. Inflows and outflows of cash from the acquisition and disposal of enterprises are also shown here.

41. Financing activities

Cash flows from financing activities are derived from actual payment transactions and include not only the take-up and repayment of credits and other financial liabilities, but also cash flows between the Group and its shareholders, such as dividend payments, for example.

Changes in the balance sheet items which are considered as movements in the Group cash flow statement are adjusted to exclude non-cash effects of currency translation and changes in companies included in the consolidation. Further, investing and financing transactions that have not led to changes in cash and cash equivalents are not included in the cash flow statement. For these reasons changes to the balance sheet items concerned in the Group cash flow statement are not directly reconcilable to the corresponding amounts in the published consolidated balance sheet.

Other disclosures

42. Company acquisitions and disposals

a) Sale of shareholding in Pharmtrace GmbH

In September 2007 Eckert & Ziegler Radiopharma GmbH sold its 30 % shareholding in Pharmtrace klinische Entwicklung GmbH, Berlin (in short: Pharmtrace) to the other incorporators. Within the Group Pharmtrace was valued at equity. The sales price was EUR 15 thousand and the at equity book value amounted to EUR 6 thousand resulting in a gain from the sale of EUR 9 thousand.

b) Acquisition of MC Pharma GmbH

On September 17, 2007 Eckert & Ziegler f-con Europa GmbH acquired 100 % of the shares of MC Pharma GmbH, Bonn. Eckert & Ziegler AG holds 61 % of the voting shares in Eckert & Ziegler f-con Europe GmbH. The total purchase consideration amounted to EUR 843 thousand of which EUR 600 thousand was paid in cash. A part of the purchase price amounting to EUR 181 thousand was provided by the vendor as an additional loan repayable at the end of 2008. An amount of EUR 62 thousand was incurred as additional expenses in connection with the acquisition of the shares.

The acquisition was included in the consolidated accounts in accordance with the acquisition method whereby the results of the company are included in the present set of accounts as from the date of acquisition. The purchase price, which includes the additional expenses associated with the acquisition, was allocated to the assets acquired on the basis of their fair values at the time of the acquisition. This allocation of the purchase price produced a bad will of EUR 120 thousand, which was taken to income and appears under the item "Other Income" in the income statement. The allocation of the purchase price on the basis of the estimated fair values of the assets was as follows (see table A on the right):

As a result of the acquisition of MC Pharma GmbH cash amounting to EUR 474 thousand was obtained. Prior to the acquisition the book value of the net assets acquired amounted to EUR 672 thousand. The profit of Eckert & Ziegler EURO-PET Köln/Bonn GmbH included in these consolidated financial statements amounts to EUR 69 thousand. If the company had already been included in the consolidated accounts as from January 1, 2007 Group turnover would have been higher by EUR 2,245 thousand and the consolidated profit would have been higher by EUR 219 thousand.

c) Acquisitions and disposals since the balance sheet date

In February 2008 Eckert & Ziegler AG injected its shareholding in Eckert & Ziegler BEBIG GmbH as a non-cash capital contribution into International Brachytherapy S.A. (IBt), Seneffe (Belgium) and received in return as consideration resulting from a capital increase 38.5% of the common stock (or 29.9% of the voting stock) of IBt. In addition, it was granted an option to acquire additional voting stock. The nominal value of the 6.75 million shares of common stock newly issued in conjunction with the capital increase was fixed at EUR 3.47 per share or EUR 23.4 million in total.

Table A Market value
Book value at the
at the time Reval- time of
of acquisition uation acquisition
TEUR TEUR TEUR
Intangible assets 132 0 132
Property, plant and equipment 2,663 69 2,732
Inventories 25 0 25
Receivables 979 0 979
Non-current assets
and prepaid expenses 97 0 97
Money in the bank
and cash assets 474 0 474
Deferred tax receivables 0 244 244
Loan liabilities -3,237 0 -3,237
Provisions -226 0 -226
Liabilities -49 0 -49
Other current liabilities -186 0 -186
Deferred tax 0 -22 -22
Net identifiable
Assets 672 291 963
Badwill -120
Purchase price for the
company acquisition
843
Less money in the bank
and cash assets
acquired -474
Net cash flow from
acquisition of
subsidiaries
369

Details of the purchase price allocation and the presentation of the transactions in the consolidated accounts are currently being prepared. Owing to the complexity of the transactions and the proximity of the acquisition date to the due date for the presentation of the consolidated financial statements it was not practically possible to include these details in these consolidated financial statements.

43. Employee share scheme

On April 30, 1999, the annual general meeting authorized the Executive Board to set up a share option plan for employees and management of the company and its subsidiaries. The annual general meeting of May 20, 2003 made minor revisions to some details of the plan. The employee share scheme decided on by the Executive Board with the consent of the Supervisory Board provides for the granting of options to purchase a maximum of 300,000 shares from the authorized but unissued share capital, provided the company does not redeem the option rights by the transfer of its own shares or by making a cash payment. A single option entitles the holder to receive one share. The effective price for the initial tranche of options is equivalent to the share price fixed at the company's stock exchange flotation, while the effective price for subsequent tranches will be calculated from the average price of the Eckert & Ziegler's share on the last five trading days prior to the passing of the Executive Board resolution on the granting of options.

The earliest time when the options granted may be exercised is after a vesting period of two years, counting from the date of issue and only within specified exercise dates. In addition, exercise is dependent on reaching certain performance criteria. The increase in the company's share price in the period between the issue day and the first effective date must exceed the increase in the Neuer Markt Index (or after the termination of that index, the rise in the Technology All-Share Index) during the same period. Options must be exercised within five years of the vesting period. In the event of termination of employment, options not yet exercised lapse. If the performance criteria are met, the options granted in 2006 (8th tranche/tranche 2006) may be first exercised during the second quarter of 2008.

In 2007 the vesting period for the options granted in 2005 (7th tranche/tranche 2005) expired. It was established in the financial year that the performance criteria were not satisfied in relation to the

options granted in 2005. All options of these tranches have thus lapsed.

In 2006 the vesting period for the options granted in 2004 (6th tranche/tranche 2004) expired. It was established in 2006 that the performance criteria were satisfied in relation to the options granted in 2004. Thus, the exercise of the options is possible in principle. The first period for exercising options commenced on August 26, 2006, with the last possible date being August 26, 2011.

In 2005 the vesting period for the options granted in 2003 (5th tranche/tranche 2003) expired. It was established in 2005 that the performance criteria were satisfied in relation to the options granted in 2003. Thus, the exercise of the options is possible in principle. The first period for exercising options commenced on August 9, 2005, with the last possible date being July 25, 2010.

In 2004 it was established that the performance criteria were satisfied in relation to the options granted in 2002 (4th tranche/tranche 2002). Thus, the exercise of the options in this tranche is possible in principle. The first period for exercising options commenced on August 28, 2004, with the last possible date being August 25, 2009.

For the tranches issued in the years 2000 (2nd tranche/tranche 2000) and 2001 (3rd tranche/ tranche 2001) the performance criteria were not met; all options of these tranches have thus lapsed.

It was established in the financial year 2002 that the performance criteria were satisfied in relation to the options granted in 1999 (1st tranche/tranche 1999). Thus, the exercise of the options is possible in principle. The first period for exercising options commenced on March 28, 2002, with the last possible date being February 25, 2007. The remaining options in these tranches lapsed on that date.

Movements in the number of outstanding share options in the last two financial years are as follows:

2007 2006
Weighted Weighted
average average
effective effective
Options price Options price
Number EUR Number EUR
140,350 10.18 119,150 9.69
0 0.00 24,500 12.19
2,700 7.63 2,900 7.45
51,500 13.85 400 5.17
86,150 8.07 140,350 10.18
67,650 6.94 83,350 9.47

The weighted average share price on the dates on which share options were exercised in the year under review of the options exercised on the effective date in the year under review was EUR 11.69.

The following table gives an overview of the share options outstanding at December 31, 2007:

Outstanding
options on Remaining
Tranche Effective December 31, exercise
price 2007 period
EUR Number Years
4th Tranche/
Tranche 2002 5.04 11,600 1.65
5th Tranche/
Tranche 2003 5.30 11,050 2.57
6th Tranche/
Tranche 2004 7.84 45,000 3.65
8th Tranche/
Tranche 2006 12.19 18,500 5.37
86,150

In accounting for the employee share scheme the company applies the relevant standard for this, IFRS 2 (Share-based Payment). Under IFRS 2, share-based compensation payments that are made through equity instruments are to be measured at fair value. The fair value of each option exercised on the effective date is calculated by means of an option price model and recognized as staff costs over the vesting period. These staff costs entail an increase in capital reserve. In the financial years 2007 and 2006 staff costs arising from the application of IFRS 2 amounting to EUR 104 thousand and EUR 117 thousand respectively arose.

The option price for options granted in the respective financial years was calculated by means of a binomial model. The non-tradable aspect was reflected in the binomial model by an option take-up factor representative of the relevant behavior of option plan participants. Further, the conditions for exercising options were taken into account by a discount on the option price. In 2007 no new options were issued. The following assumptions were made in the calculation of option prices for the share options issued in 2006:

2006

Expected dividend income per share EUR 0.15
Risk-free interest rate 3.83%
Expected volatility 38.44%
Expected lifetime 2.18 years
Fair Value EUR 4.17

44. Leasing agreements

a) Financial commitments as lessee

The company has entered into capitalized leasing agreements (capital and finance leases) and noncapitalized leasing agreements (operating leases) relating to equipment, vehicles, and land and buildings. Rental and leasing expense amounted in the financial years ending December 31, 2007 and 2006 to EUR 1,038 thousand and EUR 838 thousand respectively.

The company has entered into a long-term operating lease in connection with the self-constructed administration and production building in Berlin (capital and finance lease). This lease results in annual payments of EUR 167 thousand, EUR 89 thousand of which, however, is offset against the construction costs of the building. The lease runs initially until December 31, 2014; on expiry of this period the company has the right to opt for an extension to the lease until the suspense account set up for the newly erected building has been cleared. This right can be exercized on several occasions and might only apply to parts of the building. The lease payments for all areas may not be increased before December 31, 2014; at this time the lease payments for newly created areas will be renegotiated.

The future minimum lease payments under non-cancelable operating leases (with initial or remaining lease terms in excess of one year) and future minimum capital lease payments as of December 31, 2007 are as follows:

Sundry rental
and leasing
agreements
Of which
financial
leases
Present values
of the financia
leases
TEUR TEUR TEUR
At the year-end
(December 31)
in each case
2008 1,182 113 85
2009 1,094 113 90
2010 770 54 44
2011 550 0 0
2012 521 0 0
Thereafter 1,011 0 0
Total minimum
rental or lease
payments 5,128 280 219

The finance leases are solely in respect of property, plant and equipment. The net book value of the assets on December 31, 2007 was EUR 237 thousand. In the year under review EUR 113 thousand was expensed in respect of finance leases. There are no conditional rental payments either in the year under review or in the future. Moreover, the leasing arrangements contain no sort of restrictions or obligations.

b) Future operating income as lessor

The company as lessor is recording income from operating leases from property, plant and equipment. The expected operating income will amount to EUR 40 thousand for 2008 to 2011 and EUR 23 thousand for 2012 respectively.

45. Sundry financial commitments and contingent liabilities

Before a participating interest had been taken in the company, Eckert & Ziegler f-con Deutschland GmbH had already given a guarantee to secure a lease of f-con Regensburg Betriebs GmbH in favor of Deutsche Leasing AG. f-con Pharma AG, Vienna, and CTI (Siemens) are also jointly liable on this guarantee. The guarantee is for EUR 4.8 million. It is not envisaged that Eckert & Ziegler f-con Deutschland GmbH will have to honor this guarantee.

With a lawsuit issued on January 17, 2006 against Eckert & Ziegler AG, HEK GmbH of Lübeck is demanding the payment of the sum of EUR 709,752.63 and the transfer of 35,450 shares. This claim is chiefly based on an earn-out arranged in a purchase agreement dated March 15, 2004 involving Eckert & Ziegler MMI

(formerly MCP Medical International GmbH). Eckert & Ziegler AG considers this claim to be unfounded, as the conditions for the payment of the earn-out have not arisen.

At the time of the report, Eckert & Ziegler AG, Eckert & Ziegler Bebig GmbH and Eckert & Ziegler Eurotope GmbH are undergoing an audit. The consequences of this audit are uncertain, particularly as there are various effects which will partially compensate for each other and there are individual matters which have not been finally clarified yet. It is possible that a one-sided interpretation by tax office staff could lead to a payment of tax arrears or the risk of litigation.

46. Segmental reporting

The Eckert & Ziegler Group has organized its business activities into three operational reporting units. These individual segments supply different products and are also separated organizationally by location.

The accounting principles applied to the individual segments are the same as those described in the summary of significant accounting policies (see Note 3). Segmental information is unconsolidated. This corresponds to the information used by the Executive Board as part of regular reporting. Intersegment transactions are accounted for at market prices.

The Nuclear Imaging and Industry segment manufactures and sells standards as well as radiation source materials for industrial and medical applications. Standards are radioisotopes for calibrating purposes. They are generally sold to scientific institutions. Industrial radiation source materials are used in various kinds of control and instrumentation for industrial equipment and other radiometrical devices, such as safety installations at airports. They are sold to manufacturers of the equipment or their operators. The medical radiation source materials include radioactive sources for the calibration of gamma cameras.

The Therapy segment is focused on product development, manufacture and market introduction as well as the sale of radioactive products for the treatment of cancer. The main priorities are the treatment of prostate cancer with radioactive iodine seeds. Low and high-dose rate radiotherapy equipment are another important component of the segment. The product range, which is directed mainly at radiotherapists, is complemented with iridium wire sources as well as different therapy accessories.

Nuclear Imaging
Dec. 1, 2007 and Industry Therapy Radiopharmacy Others Total
TEUR TEUR TEUR TEUR TEUR
Sales to external customers 24,966 20,822 8,629 27 54,444
Sales to other segments 76 520 20 974 1,590
Total segmental sales 25,042 21,342 8,649 1,001 56,034
Depreciation & amortization -1,159 -1,513 -937 -122 -3,731
Non-cash income and expense -98 43 -277 -766 -1,098
Segment profit
before minority interests 2,822 742 -925 -528 2,111
Segmental assets 27,820 18,740 17,384 37,982 101,926
Segmental liabilities -12,591 -15,410 -20,034 -5,215 -53,250
Capital investment 825 2,109 4,542 3 7,479
Nuclear Imaging
Dec. 1, 2006 and Industry Therapy Radiopharmacy Others Total
Dec. 1, 2006 and Industry Therapy Radiopharmacy Others Total
TEUR TEUR TEUR TEUR TEUR
Sales to external customers
Sales to other segments
25,172
478
19,836
234
5,362
9
8
936
50,378
1,657
Total segmental sales 25,650 20,070 5,371 944 52,035
Depreciation & amortization -1,319 -2,324 -492 -411 -4,546
Non-cash income and expense* 289 -30 881 -322 818
Segment profit from continuing
operations before
minority interests
3,194 833 -978 361 3,410
Segment profit from relinquished
operations 0 0 -670 78 -592
Segmental assets 28,392 21,806 7,034 38,126 95,358
Segmental liabilities -12,784 -17,761 -9,415 -6,979 -46,939
Capital investment 696 3,261 219 9 4,185

* Non-cash income and expense had to be corrected for 2006.

The segmental allocation was not correct.

With business premises in Berlin, Bonn and Milan, Radiopharmacy is the newest and fastest-growing segment in the Group. Products in the segment include radioactive contrast media for positron emission tomography (PET) and synthesis modules for manufacturing radio-pharmaceuticals. The equipment is used both in the practice of nuclear-medical diagnostics and research.

A further segment which represents the costs and operating income of the Berlin holding company is not operationally active.

Reconciliation to
Group financial statements 2007 2006
TEUR TEUR
Group net income/ loss
beforeminorityinterest
Total segments 2,111 3,410
Elimination of inter-segmental
gains (-) / losses 39 -273
Consolidated Group net income/
loss beforeminorityinterest 2,150 3,137
Segmentalassets
Total segments 101,926 95,358
Elimination of inter-segmental
shares, equity investments and
receivables -37,420 -35,302
Deferred tax assets 3,081 4,118
Consolidated totalassets 67,587 64,174
Segmental liabilities
Total segments 53,250 46,939
Elimination of inter-segmental liabilities -23,493 -20,801
Deferred tax liabilities 1,339 1,706
Consolidated liabilities 31,096 27,844

Total segmental turnover to external customers agree to the consolidated amounts in each case.

Sales by

geographic
region 2007 2006
(EUR in millions) EUR % EUR %
North America 19.0 35 18.4 36
Europe 30.8 56 26.1 52
Asia/Pacific 2.6 5 2.8 6
Others 2.0 4 3.1 6
Totals 54.4 100 50.4 100

The breakdown under geographical region is based on the location of the service recipient. Sales in North America relate almost exclusively to the US.

The following table shows the consolidated assets, liabilities (deducting deferred taxes) and investment by geographical region.

Assets, liabilities & investment by geographic region

Year 2007
TEUR TEUR TEUR
Assets Liabilities Investments
North America 20,958 6,372 623
Europe 43,491 23,352 3,839
Totals 64,449 29,724 4,462

Assets, liabilities & investment by geographic region

Year 2006
TEUR TEUR TEUR
Assets Liabilities Investments
North America 22,722 7,117 683
Europe 37,333 19,021 3,495
Totals 60,055 26,138 4,178

Major customers

In the segment 'Therapy', approximately EUR 1.3 million of sales were to one major customer during 2007 (equates to approximately 2% of the consolidated Group sales).

47. Related persons and enterprises

Under IAS 24, transactions with persons or enterprises which Eckert & Ziegler AG controls or is controlled by are to be disclosed. Transactions by Eckert & Ziegler AG with related persons and enterprises are performed under the conditions for outside third parties.

a) Management members in key positions

Executive Board

Dr. Andreas Eckert (Chief Executive Officer, responsible for the divisions Management, Investor Relations, Finance, Business Development as well as the Nuclear Medicine and Industry segment), Berlin, businessman

In other committees: Chairman of the Board of Directors Eckert & Ziegler Isotope Products Inc. (IPL), Burbank, USA

Dr. Edgar Löffler (member of the Executive Board, responsible for the Therapy segment), Berlin, medical physicist

In other committees: Member of the Board of Directors Eckert & Ziegler Isotope Products Inc. (IPL), Burbank, USA

until December 31, 2007:

Dr. Andreas Hey (member of the Executive Board, responsible for the Radiopharmacy segment), Berlin, physician

In other committees: Member of the Board of Directors Eckert & Ziegler Isotope Products Inc. (IPL), Burbank, USA

from March 1, 2008:

Dr. André Heß (member of the Executive Board, responsible for the Radiopharmacy segment), Berlin, certified chemist and industrial engineer In other committees: None

Supervisory Board

The following were members of the Supervisory Board during 2007:

Prof. Dr. Wolfgang Maennig (Chairman), Berlin, university professor

In other control committees: Ecodasa AG, Berlin; Berliner Verkehrsbetriebe (BVG) AöR, Berlin; Hamburgisches WeltWirtschaftsInstitut (HWWI) GmbH, Hamburg

Ralf Hennig, Berlin (Vice-Chairman), management consultant In other control committees: None

Prof. Dr. Ronald Frohne, Berlin, lawyer and auditor, honorary professor

In other control committees: Würzburger Versicherungs-Aktiengesellschaft, Würzburg; TAG Tegernsee Immobilien- und Beteiligungs-Aktiengesellschaft, Hamburg; Medienboard Berlin-Brandenburg GmbH, Potsdam; TELLUX Beteiligungsgesellschaft mbH,

Munich; Scholz & Friends AG, Berlin; AGICOA – Association de Gestion Internationale Collective des Oeuvres Audiovisuelles, Geneva; CAB (The Feature Film Producers' Association for the Distribution of Fees in Pursuance of Section 35 of the Danish Copyright Act), Copenhagen

Prof. Dr. Nikolaus Fuchs, Berlin, management consultant and honorary professor In other control committees: None

Hans-Jörg Hinke, Berlin, businessman In other control committees: None

Frank Perschmann, Berlin, businessman In other control committees: None For the remuneration of Executive Board and Supervisory Board we refer you to the Management Report.

As of December 31, 2007, there were no advance payments or loans in existence to members of the Executive Board or Supervisory Boards of Eckert & Ziegler AG.

b) Other related persons and enterprises

– Eckert Strategieberatung und Kapitalbeteiligungsgesellschaft mbH ("Eckert Consult") which holds 37.9 percent of the shares in Eckert & Ziegler AG and whose sole shareholder is Dr. Andreas Eckert, Chief Executive Officer of Eckert & Ziegler AG.

– NEMOD Verwaltungs GmbH, formerly: jojumarie Intelligente Instrumente GmbH ("jojumarie GmbH"), in which Eckert Consult has an indirect holding (via Nemod Immuntherapie GmbH). Dr. Eckert is one of the general managers of NEMOD Verwaltungs GmbH.

– Glycotope GmbH which is 37.41 percent owned by Eckert Consult.

– Mr. I. Simmer and Mr. J. Sadlo, general managers and, at the same time, minority interest shareholders of the subsidiary, Eckert & Ziegler Cesio s.r.o.

– Mr. A. Schmidt, general manager and, at the same time, minority interest shareholder of the subsidiary, Eckert & Ziegler f-con Europe GmbH.

– Dr. Stabell, general manager and, at the same time, minority interest shareholder of Eckert & Ziegler EURO-PET Berlin GmbH.

In 2007 and 2006, the following transactions were conducted with these related persons and enterprises:

Eckert & Ziegler AG provided various administrative services in the year under review for Nemod Immuntherapie GmbH and Nemod Verwaltungs GmbH. For this, expenses of EUR 4.0 thousand were billed.

Since January 1, 2004, an agreement between Glycotope and Eckert & Ziegler BEBIG GmbH has been in force, whereby Eckert & Ziegler BEBIG GmbH renders IT and payroll services. The monthly fee is based on the actual costs incurred. In the year under review, Eckert & Ziegler BEBIG GmbH received EUR 13 thousand for services rendered.

In 2004, Eckert & Ziegler AG granted the general managers and minority interest shareholders of Eckert & Ziegler Cesio s.r.o., Mr. I. Simmer and Mr. J. Sadlo, loans of EUR 234 thousand each. The loans bear interest at 2 percent and are due to be repaid with interest on September 30, 2008.

Mr. Schmidt granted the subsidiary, Eckert & Ziegler f-con Europe GmbH, two loans. As of December 31, 2007, the loan amounted to EUR 455 thousand including interest.

Dr. Stabell receives goods deliveries from the subsidiary, Eckert & Ziegler EURO-PET Berlin GmbH, at market prices. Invoices amounted to EUR 30 thousand for the financial year. As of December 31, 2007, receivables stood at EUR 4 thousand.

The balances which the Eckert & Ziegler Group has with related persons and enterprises in respect of accounts receivable, loan receivables, accounts payable and loan payables as of December 31, 2007 and 2006, are as follows:

2007 2006
TEUR TEUR
Trade accounts receivable from
related persons and enterprises 12 27
Loans receivable from related
persons and enterprises 499 489
Trade accounts payable to
related persons and enterprises 10 6
Borrowings from related persons 455 177

48. Post-balance sheet events

In February 2008, Eckert & Ziegler AG transferred the shares of its implant business in Eckert & Ziegler BEBIG GmbH as a non-cash investment to International Brachytherapy S.A. (IBt), Seneffe (Belgium), and for this received 38.5 percent of IBt's ordinary shares

(which equates to 29.9 percent of the voting rights) from a capital increase.

Other disclosures required under HGB

49. Other operating income/expense

Other operating income/expense contains income and expense relating to other accounting periods of EUR 194 thousand (2006: EUR 268 thousand) and EUR 39 thousand (2006: EUR 173 thousand) respectively. The income consists of the release of provisions and income from the sale of non-current assets. The expense represents losses from the disposal of noncurrent assets.

50. Cost of materials

In financial year 2007, the cost of materials amounted to EUR 16,928 thousand (2006: EUR 16,349 thousand).

51. Auditors' fees

In financial year 2007, audit fees of EUR 185 thousand (2006: EUR 165 thousand) were charged in respect of the audit of the annual consolidated financial statements as well as fees of EUR 5 thousand for consultation relating to the preparation for a planned due diligence process.The auditors did not carry out any other functions.

52. Other information

By virtue of its inclusion in the consolidated financial statements of Eckert & Ziegler AG, Eckert & Ziegler BEBIG GmbH avails itself of the exempting clause of Section 264 para. 3 HGB under which an audit of the financial statements required by Section 316 HGB may be dispensed with.

53. Declaration under the German Corporate Governance Code in accordance with section 161 AktG (declaration of conformity)

The declaration prescribed by Section 161 AktG for Eckert & Ziegler AG as a quoted company concerning observance of the recommendations of the German Corporate Governance Code has been furnished by the Executive Board and Supervisory Board and is available permanently to shareholders through the company's website.

Executive Board and Supervisory Board, Dec. 31, 2007

Stock Stock options
Dr. Andreas Eckert
(Eckert Consult GmbH)
Executive Board 2,010
(1,230,446)
10,000
(0)
Dr. Andreas Hey Executive Board 0 0
Dr. Edgar Löffler Executive Board 10,250 16,000
Prof. Dr. Wolfgang Maennig Supervisory Board 0 0
Ralf Hennig Supervisory Board 141 0
Prof. Dr. Ronald Frohne Supervisory Board 0 0
Prof. Dr. Nikolaus Fuchs Supervisory Board 0 0
Hans-Jörg Hinke Supervisory Board 0 0
Frank Perschmann Supervisory Board 1,000 0

In the financial Year from January 1 to December 31, 2007

Costs
Balance Additions from Other Currency Balance
Jan. 1, 2007 company acquisitions Additions Disposal Transfers translation Dec. 31, 2007
TEUR TEUR TEUR TEUR TEUR TEUR TEUR
Non-currentassets
I. Intangibleassets
1. Goodwill 11,414 0 4 0 0 -929 10,489
2. Other intangible assets 12,513 132 2,228 8 0 -541 14,324
23,927 132 2,232 8 0 -1,470 24,813
II. Property, plantand equipment
1. Buildings on 8,044 0 367 95 268 -317 8,267
third-party land
2. Plant and 22,845 2,648 1,451 446 141 -372 26,267
machinery
3. Other plant and equipment,
fixtures and fittings
2,609 14 471 42 0 -89 2,963
4. Plants under construction 934 0 164 0 -409 -91 598
34,432 2,662 2,453 583 0 -869 38,095
Balance
Currency
Balance
Balance
Balance
Jan. 1, 2007
Additions
Disposal
Transfers
translation
Dec. 31, 2007
Jan. 1, 2007
Dec. 31, 2007
TEUR
TEUR
TEUR
TEUR
TEUR
TEUR
TEUR
TEUR
641
0
0
0
-100
541
10,773
9,948
5,301
1,021
0
0
-284
6,038
7,212
8,286
5,942
1,021
0
0
-384
6,579
17,985
18,234
2,072
367
7
0
-100
2,332
5,972
5,935
14,430
1,970
383
0
-268
15,749
8,415
10,518
2,010
373
40
0
-74
2,269
599
694
0
0
0
0
0
0
934
598
18,512
2,710
430
0
-442
20,350
15,920
17,745
24,454
3,731
430
0
-826
26,929
33,905
35,979

Statement by the Executive Board

The Executive Board of Eckert & Ziegler AG is responsible for preparing the accompanying consolidated financial statements. We have installed effective controlling and monitoring systems to guarantee compliance with accounting principles and the adequacy of reporting. These systems include the use of uniform guidelines group-wide, the use of reliable software and the selection and training of qualified personnel. With a view to the requirements of the German Business Monitoring and Transparency Act (KonTraG) we have integrated the Groups' early warning systems into a risk management system. This enables the Executive Board to identify significant risks at an early stage and to initiate appropriate measures.

The KPMG Deutsche Treuhand-Gesellschaft audited the consolidated financial statements, which were prepared in accordance with International Financial Reporting Standards (IFRS) as well as the Group management report and issued the following auditors' report.

The Supervisory Board has audited the annual financial statements and the management report of Eckert & Ziegler Strahlen- und Medizintechnik AG, the consolidated financial statements of the Eckert & Ziegler

Group, the Group management report for the Eckert & Ziegler Group and the auditors' reports. The Supervisory Board discussed all of these with the Executive Board and the auditors.

It acknowledged its agreement with the findings of the audit and has approved the annual and consolidated financial statements presented to it.

Berlin, March 26, 2008

Eckert & Ziegler Strahlen- und Medizintechnik AG

The Executive Board

Dr. Andreas Eckert Dr. Edgar Löffler

Dr. André Heß

Assurance from the legal representatives

To the best of our knowledge, and in accordance with the applicable reporting principles, the consolidated financial statements give a true and fair view of the assets, liabilities, financial position and profit or loss of the group, and the group management report includes a fair review of the development and performance of the business and the position of the group, together with a description of the principal opportunities and risks associated with the expected development of the group.

Berlin, March 14, 2008

The Executive Board

Dr. Andreas Eckert Dr. Edgar Löffler Dr. André Heß

Auditors' Report

We have audited the consolidated financial statements, comprising the balance sheet, the income statement, the statement of changes in shareholders' equity, the cash flow statement, the notes to the financial statements as well as the Group management report prepared by Eckert & Ziegler Strahlenund Medizintechnik AG, Berlin, for the business year from 1 January 2007 to 31 December 2007. Preparation of the consolidated financial statements and the Group management report in accordance with the IFRS as they are to be applied in the EU, and supplementing this in accordance with the commercial law regulations of § 315a paragraph 1 of the German Commercial Code (Handelsgesetzbuch – HGB) is the responsibility of the legal representatives of the Company. Our responsibility is to express an opinion on these consolidated financial statements and the Group management report based on our audit.

We conducted our audit of the consolidated financial statements in accordance with §317 of the HGB and the German generally accepted standards for the audit of financial statements promulgated by the German Auditors' Institute (Institut der Wirtschaftsprüfer – IDW). These standards require that we plan and perform the audit such that misstatements and infringements materially affecting the presentation of the net assets, financial position, and results of operations reported in the consolidated financial statements and in the Group management report in accordance with the applicable accounting regulations are detected with reasonable assurance. Knowledge of the business activities and the economic and legal environment of the Group and evaluations of possible misstatements are taken into account in the determination of audit procedures. The effectiveness of the accounting-related internal control system and the evidence supporting the disclosures in the consolidated financial statements and the Group management report are examined primarily on a test basis within the framework of the audit. The audit

comprises assessing the annual financial statements of the companies included in the consolidated financial statements, the determination of the scope of consolidation, the accounting and consolidation principles used, and the significant estimates made by the legal representatives, as well as evaluating the overall presentation of the consolidated financial statements and Group management report. We believe that our audit provides a reasonable basis for our opinion.

Our audit has not led to any reservations.

Berlin, March 14, 2008

KPMG Deutsche Treuhand-Gesellschaft Aktiengesellschaft Wirtschaftsprüfungsgesellschaft

Dr. Kronner Wirtschaftprüfer

Brandt Wirtschaftsprüfer

To increase public trust of the management and to monitor German joint-stock corporations which are listed on the stock exchange, the commission appointed by the German federal government presents recommendations for responsible corporate management in the German Corporate Governance Code, which is updated regularly.

In addition to legal regulations, the German Corporate Governance Code contains internationally and nationally recognized standards for good and responsible corporate management.

Eckert & Ziegler AG welcomes the substance and aims of the German Corporate Governance Code. Since its establishment, its principles have shaped responsible and transparent corporate management of Executive Board and Supervisory Board actions.

In the reporting year, too, the company adhered in the main to the recommendations of the German Corporate Governance Code. Only for well-founded reasons were there exceptions to the recommendations.

As a company listed on the stock exchange, Eckert & Ziegler is obliged in accordance with § 161 of the German Stock Companies Law to submit an annual declaration of compliance with the German Corporate Governance Code. This declaration must make it clear that the German Corporate Governance Code has been and is being complied with or which recommendations have not been or are not being applied:

Declaration on the Corporate Governance Code as per § 161 of the German Stock Companies Law

The Executive Board and Supervisory Board of Eckert & Ziegler Strahlen- und Medizintechnik AG hereby declare the following in accordance with §161 of the German Stock Companies Law:

Eckert & Ziegler Strahlen- und Medizintechnik AG will comply with the recommendations of the German Corporate Governance Code – the version of June 14, 2007 – with the following exceptions:

Deductible amount with the D&O insurance:

The D&O insurance policy taken out for the Executive Board and the Supervisory Board provides for no deductible amount.

Formation of commissions:

The Supervisory Board has established no commissions, in particular no auditing commission or nomination commission.

Executive Board remuneration:

There is currently no regulation concerning Executive Board remuneration through components with a long-term incentive effect and risk character.

Age limit for members of the Executive Board and Supervisory Board:

No age limits have been set either for members of the Executive Board or for members of the Supervisory Board.

Supervisory Board remuneration:

The members of the Supervisory Board receive no performance-based remuneration.

Since the declaration of compliance on December 3, 2006, Eckert & Ziegler Strahlen- und Medizintechnik AG has complied in full with the recommendations of the German Corporate Governance Code – the version of June 12, 2006 – excluding the exceptions stated in the Declaration.

Berlin, December 3, 2007

For the Executive Board:

Dr. Andreas Eckert

Dr. Edgar Löffler

For the Supervisory Board:

Prof. Dr. Wolfgang Maennig

Declaration of exceptions to the recommendations of the German Corporate Governance Code

The Executive Board takes the following stance – also on behalf of the Supervisory Board – in relation to the exceptions to the recommendations of the German Corporate Governance Code specified in the declaration of compliance of December 3, 2007:

Deductible amount with the D&O insurance

The agreement of a deductible amount with the D&O insurance (liability insurance for members of the Executive Board and Supervisory Board) has been dispensed with as it is not apparent that this fundamentally boosts the motivation and sense of responsibility of the members of the boards. In addition, there are currently no generally recognized principles for the appropriateness of such an arrangement.

Formation of commissions

The need to form commissions, in particular an auditing commission or nomination commission, is not viewed as a matter of priority by the Supervisory Board because of the small number of members on the Supervisory Board and the specific circumstances of the company. All of the duties conferred on such committees are therefore undertaken by the Supervisory Board itself.

Executive Board remuneration

On the basis of the experience gained with the earlier share option program, in particular in relation to how it was received by employees, no comparable follow-up program has so far been concluded for senior managers.

Age limit for members of the Executive Board and Supervisory Board

The Executive and Supervisory Boards are of the opinion that a general age limit for members of the Executive Board and Supervisory Board does not represent an appropriate criterion for searching for and excluding members of these bodies. Rather, when it comes to appointing people to the Executive Board and Supervisory Board, the fundamentally important factor is whether the members have the necessary knowledge, skills and specialist experience required.

Supervisory Board remuneration

The Executive and Supervisory Boards are of the opinion that remuneration linked to the profits of the business is not compatible with the legally prescribed function of the Supervisory Board as an independent monitoring body or with the associated requisite neutrality of interest.

Monitoring and consulting with the Executive Board

The Executive Board regularly and fully informed the Supervisory Board in fiscal year 2007 about the course of business, business policies, planning, and risk management for Eckert & Ziegler Strahlen- und Medizintechnik AG as well as for the enterprises for which it holds equity investments. The Supervisory Board was directly involved in all decisions of key importance to the business.

A total of five meetings of the Supervisory Board were held during the year under review. In addition to the meetings, the Executive Board promptly informed and consulted with the Supervisory Board regarding emergent issues. In regularly occurring individual discussions, the Chief Executive Officer informed the Chairman of the Supervisory Board about important developments and upcoming decisions. There were no Supervisory Board committees during the period under review.

Approvals of Executive Board decision proposals followed careful consideration of all relevant documents and intensive discussions with the Executive Board.

The Supervisory Board in its advisory capacity focused on the following main topics:

  • Strategic focus, in particular in
  • the area of radiopharmacy
  • Restructuring within the Group
  • Acquisitions
  • Risk management

Examination of the 2007 annual financial statement

The annual financial statements for Eckert & Ziegler Strahlen- und Medizintechnik AG, the consolidated financial statements for the Eckert & Ziegler Group, the management report for Eckert & Ziegler Strahlenund Medizintechnik AG, the management report for the Eckert & Ziegler Group, the Executive Board's proposal to the annual general meeting on the appropriation of the year's retained earnings, and the reports by the auditors, namely KPMG Deutsche Treuhand-Gesellschaft Aktiengesellschaft Wirtschaftsprüfungsgesellschaft of Berlin, were all submitted to the Supervisory Board and supplied to each of its members.

Representatives of the auditing company took part in the Supervisory Board meeting held on March 26, 2008 to evaluate the financial statements, and reported on the main audit findings. The auditors confirmed in their report that all legal requirements have been complied with, and they issued an unconditional accounts certification. The Supervisory Board acknowledged the findings of the audit with assent.

Following its concluding examination, the Supervisory Board had no reservations regarding the audited financial statements or any of the other documents submitted. It hereby approves the annual and consolidated statements presented to it.

Other

Supervisory Board member Prof. Dr. Ronald Frohne was able to participate in only two meetings of the Supervisory Board during fiscal year 2007 due to professional commitments abroad.

A word of thanks

The Supervisory Board thanks the members of the Executive Board and senior management as well as the employees of the companies belonging to the Eckert & Ziegler Group for their strong commitment and performance in fiscal year 2007.

Berlin, March 2008

The Supervisory Board

Prof. Dr. Wolfgang Maennig Chairman

of Eckert & Ziegler Aktiengesellschaft for the years ended December 31

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2007 2006
TEUR TEUR
1.
Net sales
1,001 2,040
2.
Other operating income
344 817
1,345 2,857
3.
Staff costs
a) Wages and salaries -1,355 -1,380
b) Social security and old-age provision -108 -136
- of which for pensions TEUR -21 (previous year: TEUR -25) -1,463 -1,516
4.
Depreciation and amortization
a) intangible assets of non-current assets
and property, plant and equipment -209 -498
b) on current assets if these exceed the normal
depreciation applied in the company 0 -778
-209 -1,276
5.
Other operating expense
-741 -882
6.
Income from equity investments
890 352
7.
Income arising from profit or loss takeover agreements
0 1,512
8.
Income from other securities and from loans included
under long-term investments 316 384
9.
Interest receivable and similar income
1,471 1,419
10. Write-downs on long-term investments and
on marketable securities -355 -361
11. Expense from absorption of losses 0 -1,077
12. Interest payable and similar expense -282 -313
13. Net income/loss (-) fromordinaryactivities 972 1,099
14. Income tax expense -30 5
15. Net income/loss (-) for theyear 942 1,104
16. Release of treasury stock 7 67
17. Unappropriated retained earnings/losses (-) 949 1,171

Assets of Eckert & Ziegler Aktiengesellschaft as of December 31

2007 2006
TEUR TEUR
Assets
A. Non-currentassets
I. Intangible assets
Patents, licenses, trade marks and
similar rights and software 649 854
II.
Property, plant and equipment
Other plant and equipment, fixtures and fittings 16 18
III. Long-term investments
1. Shares in affiliates 11,472 11,546
2. Loans to affiliates 3,769 4,606
15,241 16,152
Total non-current assets 15,906 17,024
B. Currentassets
II.
Receivables and other assets
1. Trade accounts receivable 4 2
2. Amounts due from affiliates 19,686 18,918
3. Other assets 809 997
20,499 19,917
II.
Securities
1. Own shares 360 366
2. Other securities 965 1,038
1,325 1,404
III. Cash at bank 493 999
Total current assets 22,317 22,320
C. Prepaid and deferred expenses 13 26
D. Deferred tax 77 87
Total assets 38,313 39,457
2007 2006
TEUR TEUR
Liabilitiesand Shareholders'equity
A. Shareholders'equity
I.
Common stock
3,250 3,250
Nominal amount of authorized but unissued common stock EUR 300 thousand
II.
Additional paid-in capital
27,166 27,166
III. Retained earnings
2. Treasury stock 360 366
4. Other retained earnings 1,069 684
1,429 1,050
IV. Unappropriated retained earnings/losses (-) 949 1,171
Total shareholders' equity 32,794 32,637
B. Deferred incomefromgovernment grants 157 206
C. Reserves
1.
Pension reserves
2.
Tax reserves Steuerrückstellungen
356
10
335
0
3.
Other reserves and accruals
634 550
1,000 885
D. Liabilities
1.
Bank borrowings
1,750 2,000
2.
Trade accounts payable
14 27
3.
Amounts due to affiliates
364 1,521
4.
Other liabilities
2,234 2,181
(of which for taxes EUR 95; 2006 TEUR 57)
(of which for social security TEUR 0;
2006 TEUR 0)
Total liabilities 4,362 5,729
Total liabilities and shareholders' equity 38,313 39,457

Afterloading therapy Short-term radiation in cancer treatment in which a mostly wire-bonded radioactive source is propelled electrically for a brief period into the target tumor area by means of a tube-like catheter or by cannulas. Several sessions are usually necessary.

Eye applicator Anatomically formed radiation source for radiation treatment of eye tumors.

Blood radiation equipment BIOBEAM blood radiation equipment works by means of gamma rays directed at blood, blood components and biological material. It is particularly suited for use in immune hematology, transfusion medicine and radio-biological research.

Brachytherapy Contact treatment mainly in the form of irradiation with a minimal distance between the source of radiation and the tissue which is to be irradiated.

D&O Insurance Directors' and officers' liability insurance. Liability insurance for the company management of a joint-stock corporation; in this case it is for the members of the Executive Board and Supervisory Board. It is invoked if claims for compensation arise through management's failure to exercise the duty of care expected from a duly conscientious businessman.

DOTA-peptides Peptides which bind to very specific cell receptors (e.g. in specific tumors) and induce regulative effects there.

Flood source An emission source with an extended emission range (e.g. Perflexion™).

Fluoroethylcholine A newly developed, highly specific radioactive agent for precise diagnosis of prostate cancer which is used in positron emission tomography (PET).

Fluorodeoxyglucose (FDG) Glucose marker. Radioactively labeled glucose (sugar).

Gamma camera Camera for imaging diagnosis in nuclear medicine. It is used in scintigraphy.

IFRS (Abbreviation for International Financial Reporting Standards) Standards to which the present Group financial statements were drawn up.

Implants Natural or synthetic elements implanted in the body (here they are synonymous with seeds).

Implantation Placement or insertion of foreign materials into an organism.

Incontinence Inability to control the release of urine and/or stools.

Interstitial A small space in a tissue or interstice between tissues (interstitium).

Iridium source Iridium-192 is a radioactive isotope for medical source materials whose main characteristic is that a high dosage can be concentrated in a small volume. These kinds of sources are therefore used predominantly as a short-term implant in afterloading.

Isotope Chemical element having the same atomic number but different atomic weight. Isotopes can be stable or can disintegrate when subject to ionizing radiation (radioactive isotopes).

Iodine-125 Radioisotope of iodine. Low-energy photon radiation is used therapeutically.

Calibration Referencing of measuring instruments to specified standards.

Calibrated-reference emitters Radioactive sources used as a reference standard for measuring instruments.

Cobalt sources (CO-60) Radioactive source with the radioactive nuclide Co-60 which is well suited for radiating the surface of tumors. The MultiSource® cancer radiation system uses cobalt-60 sources.

Contrast medium Medicinal product which improves the representation of structures and functions of the body in imaging processes.

Nuclear Imaging Imaging for nuclear medical purposes.

Nuclear medicine Specialist medical area concerned with the diagnostic and therapeutic use of open, usually ephemeral radionuclides.

Oncology Specialist medical area which deals with the origin and treatment of malignant tumors.

Ophthalmology Science of the eye and eye diseases.

Peptide Organic chemical compound derived from linking several amino acids.

Permanent implants Implants intended to remain in the organism/body permanently.

PET scanner Device used for positron emission tomography (PET), a specialized imaging process in nuclear medicine.

PET tracers Radioactively marked substances introduced into living organisms to diagnose cancer in the framework of PET examinations.

Photon Tiny energy package.

Positron Elementary particle with the mass of an electron, but with positive charge.

Positron emission tomography (PET)Nuclear medical examination for producing sectional images using photons created by positron decay.

Prostate Prostate gland. Chestnut-size organ situated around theneck of the male urethra.

Radioactivity Property of unstable nuclides emitting spontaneously or through disintegration of the atomic nuclei alpha and beta rays or electromagnetic waves (gamma rays).

Radiochemistry Field of nuclear chemistry concerned with the production of radionuclides.

Radiodiagnostics Diagnostic radiopharmaceuticals. See also Radiopharmaceuticals.

Radiography Conventional X-raying.

Radioisotope See Radionuclide.

Radionuclide Radioactive isotope.

Radio-oncology Also radiotherapy. An area of medicine dealing with the treatment of malignant tumors by means of ionizing rays.

Radiopharmaceuticals Substances and medications which, because of their radioactive nuclides, are effective as diagnostic and therapeutic agents in nuclear medicine.

RadiopharmacyDevelopment and production of radiopharmaceuticals.

Raw isotope Radioactive starting substance for producing radiation sources.

Seed Small metal pins containing radioisotopes for interstitial radiation therapy.

SPECT Abbreviation for Single Photon Emission Computer Tomography. Imaging method in nuclear medicine, and also PET.

Emitter Here: device that transmits radioactive rays. Sometimes also referred to as "source".

Synthesis modules Here: components of the modular equipment system of the product Modular-Lab for automated synthesis of radiopharmaceuticals and radioactive chemicals.

Scintigraphy Nuclear medical imaging method used mainly with gamma rays for functional diagnostics.

Scintillator Fluorescent material for detecting charged particles and gamma rays.

Therapy accessories Microprocessor-controlled devices used in treatments carried out using radioactive material, e.g. block and compensator cutting equipment and crucibles.

Cyclotron Circular particle accelerator for production of radioactivesubstances.

Eckert & Ziegler Strahlen- und Medizintechnik AG

Nuclear Medicine and Industry segment Therapy segment

88 Eckert & Ziegler . Annual Report 2007

Radiopharmaceutical segment

Financial Calendar

March 28, 2008 Annual Report 2007

March 28, 2008 Balance Press Conference in Berlin

April 15, 2008 Medtech Day in Frankfurt

May 6, 2008 Quarterly Report I/2008

June 11, 2008 Annual General Meeting in Berlin

August 5, 2008 Quarterly Report II/2008

November 4, 2008 Quarterly Report III/2008

November 2008 German Equity Capital Forum in Frankfurt

Contact

Eckert & Ziegler Strahlen- und Medizintechnik AG

Thomas Scheuch Investor Relations

Robert-Rössle-Str. 10 13125 Berlin Germany www.ezag.de

Telephone +49 (0) 30 94 10 84 - 0 Telefax +49 (0) 30 94 10 84 - 112 E-mail [email protected]

ISIN DE0005659700 WKN 565 970

Imprint

Publisher Eckert & Ziegler Strahlen- und Medizintechnik AG, Berlin

Photography Thomas Lotzow, Berlin Archive Achim Gaasterland, Köln Tobias Schneider, Berlin Archiv BBB Management GmbH, Berlin

Layout RWS Group GmbH, Berlin

Printed by Stock Printservice, Berlin

Eckert & Ziegler . Annual Report 2007

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