Kalaris Therapeutics, Inc.
Developing next-gen, long-acting anti-VEGF therapies for prevalent retinal diseases.
KLRS | NDAQ
Overview
Corporate Details
- ISIN(s):
- US0198181036
- LEI:
- Country:
- United States of America
- Address:
- 628 MIDDLEFIELD ROAD, 94301 PALO ALTO
- Website:
- https://kalaristx.com/
- Sector:
- Manufacturing
- Industry:
- Manufacture of pharmaceuticals, medicinal chemical and botanical products
Description
Kalaris Therapeutics, Inc. is a clinical-stage biopharmaceutical company dedicated to developing and commercializing treatments for prevalent retinal diseases. The company's lead product candidate is TH103, a fully humanized, recombinant fusion protein designed as a next-generation anti-VEGF agent for intravitreal delivery. Co-developed by Dr. Napoleone Ferrara, known for his work on Avastin and Lucentis, TH103 acts as a soluble decoy receptor. A key feature is its high affinity for heparan sulfate proteoglycans (HSPG), which may act as a molecular anchor to extend its intraocular retention. This mechanism aims to reduce the frequency of injections for patients with neovascular retinal diseases, such as age-related macular degeneration.
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Filings
| Date | Filing | Language | Size | Actions | |
|---|---|---|---|---|---|
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Market Data
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Financials & KPIs
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Insider Transactions
| Date | Insider Name | Position | Type | Shares | Value |
|---|---|---|---|---|---|
| No insider transactions recorded for this company. | |||||
