Zymeworks Inc. — Director's Dealing 2025

Feb 18, 2025

SEC Form 3 — Initial Statement of Beneficial Ownership

Issuer: Zymeworks Inc. (ZYME)
CIK: 0001937653
Period of Report: 2025-02-17

Reporting Person: NODELMAN OLEG (Director, 10% Owner)

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	15720161	Indirect

Holdings (Derivative)

Security	Exercise Price	Expiration	Underlying	Shares	Ownership
Pre-Funded Warrants	$0.0001		Common Stock (5086521)		Indirect

Footnotes

F1: Mr. Nodelman is the manager and controlling owner of EcoR1 Capital, LLC which is the investment adviser and general partner of private funds. The funds hold these securities directy for the benefit of their investors. Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1 Capital, LLC. Mr. Nodelman disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

F2: The pre-funded warrants do not have an expiration date.

F3: Each pre-funded warrant is exercisable to purchase one share of Common Stock, except that the pre-funded warrants cannot be exercised if, after giving effect or immediately prior to such exercise, the reporting person, together with its affiliates and any other persons whose beneficial ownership of shares of Common Stock would be aggregated with the reporting person for purposes of Section 13(d) of the Securities Exchange Act of 1934, would beneficially own more than 19.99% of the total number of issued and outstanding shares of Common Stock or voting power of the Company following such exercise.