Wave Life Sciences Ltd. — Director's Dealing 2025

Dec 11, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Wave Life Sciences Ltd. (WVE)
CIK: 0001631574
Period of Report: 2025-12-08

Reporting Person: Tan Aik Na (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-08	Ordinary Shares	S	7494	$12.75	Disposed	32894	Direct
2025-12-08	Ordinary Shares	S	7494	$15.00	Disposed	25400	Direct
2025-12-08	Ordinary Shares	M	32230	$5.37	Acquired	57630	Direct
2025-12-08	Ordinary Shares	S	15000	$12.75	Disposed	42630	Direct
2025-12-08	Ordinary Shares	S	17230	$15.00	Disposed	25400	Direct
2025-12-08	Ordinary Shares	M	45000	$4.585	Acquired	70400	Direct
2025-12-08	Ordinary Shares	S	20000	$12.75	Disposed	50400	Direct
2025-12-08	Ordinary Shares	S	25000	$15.00	Disposed	25400	Direct
2025-12-08	Ordinary Shares	M	21000	$3.50	Acquired	46400	Direct
2025-12-08	Ordinary Shares	S	21000	$12.75	Disposed	25400	Direct
2025-12-08	Ordinary Shares	M	21000	$5.97	Acquired	46400	Direct
2025-12-08	Ordinary Shares	S	21000	$12.75	Disposed	25400	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-12-08	Share Option (right to buy)	$5.37	M	32230	Disposed	2029-08-12	Ordinary Shares (32230)	Direct
2025-12-08	Share Option (right to buy)	$4.585	M	45000	Disposed	2028-08-07	Ordinary Shares (45000)	Direct
2025-12-08	Share Option (right to buy)	$3.50	M	21000	Disposed	2027-08-15	Ordinary Shares (21000)	Direct
2025-12-08	Share Option (right to buy)	$5.97	M	21000	Disposed	2026-08-16	Ordinary Shares (21000)	Direct

Footnotes

F1: The option exercise and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 6, 2025.

F2: These share options are fully vested.