Schrodinger, Inc. — Director's Dealing 2021

May 7, 2021

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Schrodinger, Inc. (SDGR)
CIK: 0001490978
Period of Report: 2021-05-05

Reporting Person: Abel Robert Lorne (See Remarks)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2021-05-05	Common Stock	M	13377	$1.57	Acquired	13377	Direct
2021-05-05	Common Stock	M	2496	$1.57	Acquired	15873	Direct
2021-05-05	Common Stock	S	6429	$68.972	Disposed	9444	Direct
2021-05-05	Common Stock	S	8490	$69.973	Disposed	954	Direct
2021-05-05	Common Stock	S	954	$71.017	Disposed	0	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2021-05-05	Stock Option (right to buy)	$1.57	M	13377	Disposed	2024-05-18	Common Stock (13377)	Direct
2021-05-05	Stock Option (right to buy)	$1.57	M	2496	Disposed	2025-07-19	Common Stock (2496)	Direct

Footnotes

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 17, 2020.

F2: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $68.50 to $69.47, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) through (4) of this Form 4.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $69.51 to $70.36, inclusive.

F4: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.61 to $71.17, inclusive.

F5: This option was granted on May 19, 2014 and is fully vested.

F6: The option was granted on July 20, 2015 and is fully vested.