PYC THERAPEUTICS LIMITED — Director's Dealing 2010

Dec 16, 2010

Appendix 3Y

Change of Director’s Interest Notice

Name of entity PHYLOGICA LIMITED ABN 48 098 391 961

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	JOHN DOUGLAS WILSON
Date of last notice	5 November 2009

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	INDIRECT
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	MAINZ CONSULTANTS LTD GILLESPIE NOMINEES LTD DIRECTOR AND SHAREHOLDER
Date of change	16 DECEMBER 2010
No. of securities held prior to change	INDIRECT 300,000 UNLISTED OPTIONS 618,337 ESOP OPTIONS 10,000 CONVERTIBLE NOTES
Class	ESOP OPTIONS
Number acquired	500,000
Number disposed	NIL
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	NIL
No. of securities held after change	INDIRECT 300,000 UNLISTED OPTIONS 1,118,337 ESOP OPTIONS 10,000 CONVERTIBLE NOTES
Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy-back	APPROVED BY SHAREHOLDERS AT GENERAL MEETING ON 30 NOVEMBER 2010

1

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract Nature of interest Name of registered holder (if issued securities) Date of change No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed Interest acquired Interest disposed Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation Interest after change

2

• See chapter 19 for defined terms.

Appendix 3Y Page

11/3/2002

Appendix 3Y

Change of Director’s Interest Notice

Name of entity PHYLOGICA LIMITED ABN 48 098 391 961

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	NICHOLAS WOOLF
Date of last notice	4 OCTOBER 2010

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	DIRECT
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.
Date of change	16 DECEMBER 2010
No. of securities held prior to change	600,000 SHARES
Class	ORDINARY SHARES AND ESOP OPTIONS
Number acquired	524,500 SHARES 1,400,000 ESOP OPTIONS
Number disposed	NIL
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	8 CENTS PER SHARE NIL PER ESOP OPTION
No. of securities held after change	1,124,500 SHARES 1,400,000 ESOP OPTIONS
Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy-back	APPROVED BY SHAREHOLDERS AT GENERAL MEETING ON 30 NOVEMBER 2010

1

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract Nature of interest Name of registered holder (if issued securities) Date of change No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed Interest acquired Interest disposed Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation Interest after change

2

• See chapter 19 for defined terms.

Appendix 3Y Page

11/3/2002